KR20150083115A - 리보조절인자 조성물 및 사용 방법 - Google Patents

리보조절인자 조성물 및 사용 방법 Download PDF

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KR20150083115A
KR20150083115A KR1020157014990A KR20157014990A KR20150083115A KR 20150083115 A KR20150083115 A KR 20150083115A KR 1020157014990 A KR1020157014990 A KR 1020157014990A KR 20157014990 A KR20157014990 A KR 20157014990A KR 20150083115 A KR20150083115 A KR 20150083115A
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rna
domain
factor
tarna
sequence
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알렉산더 에이. 그린
펭 이인
제임스 제이. 콜린스
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프레지던트 앤드 펠로우즈 오브 하바드 칼리지
트러스티스 오브 보스턴 유니버시티
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    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12N2320/10—Applications; Uses in screening processes
    • C12N2320/12—Applications; Uses in screening processes in functional genomics, i.e. for the determination of gene function

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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KR1020157014990A 2012-11-06 2013-11-06 리보조절인자 조성물 및 사용 방법 Withdrawn KR20150083115A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261722825P 2012-11-06 2012-11-06
US61/722,825 2012-11-06
US201361843934P 2013-07-09 2013-07-09
US61/843,934 2013-07-09

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KR20150083115A true KR20150083115A (ko) 2015-07-16

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US (2) US9550987B2 (https=)
EP (2) EP2917349B1 (https=)
JP (2) JP6130923B2 (https=)
KR (1) KR20150083115A (https=)
CN (2) CN108004238A (https=)
WO (1) WO2014074648A2 (https=)

Cited By (5)

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KR20190143037A (ko) * 2018-06-19 2019-12-30 서울대학교산학협력단 박테리아에서의 고품질 재조합 단백질 생산을 위해 전사 완료 후 번역이 개시되는 유전자 발현 카세트
KR20200028684A (ko) 2018-09-07 2020-03-17 한국화학연구원 중동호흡기증후군 바이러스 진단을 위한 세포-유리 시스템 및 이의 이용방법
KR20200145063A (ko) * 2019-06-20 2020-12-30 한국화학연구원 구제역 바이러스 진단을 위한 리보조절인자 및 이의 용도
KR20210050041A (ko) * 2019-10-25 2021-05-07 한국화학연구원 리보조절인자를 이용한 바이러스 진단을 위한 fet 통합 센서 및 이의 이용 방법
US12139715B2 (en) 2018-06-19 2024-11-12 Seoul National University R&Db Foundation Gene expression cassette capable of initiating translation after completion of transcription for producing high-quality recombinant protein in bacteria

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EP2633071B1 (en) 2010-10-27 2016-10-12 President and Fellows of Harvard College Compositions of toehold primer duplexes and methods of use
US9796748B2 (en) 2011-05-02 2017-10-24 President And Fellows Of Harvard College Spatial sequestration of dynamic nucleic acid circuits
US9550987B2 (en) 2012-11-06 2017-01-24 President And Fellows Of Harvard College Riboregulator compositions and methods of use
EP3077551B1 (en) 2013-12-06 2020-04-01 President and Fellows of Harvard College Paper-based synthetic gene networks
WO2016011089A1 (en) 2014-07-14 2016-01-21 President And Fellows Of Harvard College Compositions comprising riboregulators and methods of use thereof
US10041109B2 (en) * 2015-04-17 2018-08-07 TotemID Inc. Method for detection of a nucleic acid target sequence
WO2017040829A1 (en) * 2015-09-02 2017-03-09 President And Fellows Of Harvard College Riboregulators regulated by external stimuli and methods of use thereof
WO2017087530A1 (en) * 2015-11-16 2017-05-26 President And Fellows Of Harvard College Compositions comprising riboregulators and methods of use thereof
EP4239079B1 (en) 2016-02-17 2025-12-17 President And Fellows Of Harvard College Molecular programming tools
US10550440B2 (en) 2016-02-26 2020-02-04 Arizona Board Of Regents On Behalf Of Arizona State University Synthetic translation-sensing riboswitches and uses thereof
WO2017205668A1 (en) 2016-05-25 2017-11-30 Arizona Board Of Regents On Behalf Of Arizona State University Portable, low-cost pathogen detection and strain identification platform
IL290679B2 (en) 2016-07-05 2023-10-01 California Inst Of Techn Hybridization chain reaction based on a minimal initiator
WO2018026765A1 (en) * 2016-08-01 2018-02-08 Arizona Board Of Regents On Behalf Of Arizona State University Synthetic near-threshold translational repressors
WO2018026762A1 (en) * 2016-08-01 2018-02-08 Arizona Board Of Regents On Behalf Of Arizona State University Ultraspecific riboregulators having robust single-nucleotide specificity and in vitro and in vivo uses thereof
US11802318B2 (en) 2016-08-04 2023-10-31 Arizona Board Of Regents On Behalf Of Arizona State University Loop-mediated synthetic riboregulators
CA3034617A1 (en) 2016-08-30 2018-03-08 California Institute Of Technology Immunohistochemistry via hybridization chain reaction
WO2018053366A1 (en) * 2016-09-15 2018-03-22 President And Fellows Of Harvard College Prokaryote-inducible programmable therapy
EP3516079B1 (en) 2016-09-20 2022-06-22 President and Fellows of Harvard College Molecular product authentication systems
CN107841510B (zh) * 2016-09-20 2021-02-09 中国科学院青岛生物能源与过程研究所 一种原核细胞转录后水平控制不同基因表达比例的方法
EP3638789A4 (en) * 2017-06-12 2021-03-10 California Institute of Technology CONDITIONAL GUIDE RNAS
CN107365782A (zh) * 2017-08-29 2017-11-21 廊坊梅花生物技术开发有限公司 一种基因工程菌及其应用
CN111630178A (zh) * 2017-12-22 2020-09-04 多伦多大学管理委员会 用于在无细胞系统中使用葡萄糖计检测目标分析物的合成生物电路
US11125743B2 (en) * 2018-02-20 2021-09-21 Arizona Board Of Regents On Behalf Of Arizona State University Detection of norovirus using norovirus-specific toehold switches
CN112189055B (zh) 2018-03-22 2024-07-19 哈佛学院院长及董事 用于分子认证的方法和组合物
KR20210043605A (ko) * 2018-08-14 2021-04-21 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 핵산의 체외 검출
US11624702B2 (en) 2018-09-05 2023-04-11 Georgia Tech Research Corporation Systems and methods for quantifying analytes with minimal inter-sample variability
CN109811071A (zh) * 2019-02-22 2019-05-28 中国科学院长春应用化学研究所 一种基于血糖仪检测的免标记、免分离便携式基因检测方法
GB2582594B (en) * 2019-03-26 2023-07-19 Nanovery Ltd Apparatus, System and Method
JP2022552375A (ja) * 2019-10-15 2022-12-15 コーネル・ユニバーシティー 遺伝子治療発現カセットからの発現レベルを調節するための方法
US20230022775A1 (en) * 2019-12-13 2023-01-26 President And Fellows Of Harvard College Riboregulators and methods of use thereof
WO2021219891A1 (en) 2020-05-01 2021-11-04 Enteromics Ltd. Ingestible and modular capsule for sample collection, monitoring, and/or data detection
US11952637B2 (en) 2020-06-12 2024-04-09 Arizona Board Of Regents On Behalf Of Arizona State University Rapid low-cost detection of SARS-CoV-2 using isothermal amplification and sensing methods
EP3971292A1 (en) 2020-09-22 2022-03-23 Moirai Biodesign, S.L. Rna molecule, use thereof and a process for detecting a disease by using thereof
ES2968046T3 (es) 2020-07-27 2024-05-06 Moirai Biodesign S L Molécula de ARN, uso de la misma y procedimiento de detección de una enfermedad mediante el uso de la misma
WO2022164796A1 (en) 2021-01-26 2022-08-04 California Institute Of Technology Allosteric conditional guide rnas for cell-selective regulation of crispr/cas
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WO2004046321A2 (en) 2002-11-15 2004-06-03 Trustees Of Boston University Cis/trans riboregulators
WO2006088165A1 (ja) * 2005-02-18 2006-08-24 Kyoto University 遺伝子検出用試薬及びその利用
US7745594B2 (en) * 2005-07-21 2010-06-29 California Institute Of Technology Nucleic acid-based logic circuits
EP2500427B1 (en) * 2007-11-22 2014-07-30 Japan Science and Technology Agency Translation regulation system in cell or artifical cell model by using low-molecular-weight RNA
US9550987B2 (en) 2012-11-06 2017-01-24 President And Fellows Of Harvard College Riboregulator compositions and methods of use

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190143037A (ko) * 2018-06-19 2019-12-30 서울대학교산학협력단 박테리아에서의 고품질 재조합 단백질 생산을 위해 전사 완료 후 번역이 개시되는 유전자 발현 카세트
US12139715B2 (en) 2018-06-19 2024-11-12 Seoul National University R&Db Foundation Gene expression cassette capable of initiating translation after completion of transcription for producing high-quality recombinant protein in bacteria
KR20200028684A (ko) 2018-09-07 2020-03-17 한국화학연구원 중동호흡기증후군 바이러스 진단을 위한 세포-유리 시스템 및 이의 이용방법
KR20200145063A (ko) * 2019-06-20 2020-12-30 한국화학연구원 구제역 바이러스 진단을 위한 리보조절인자 및 이의 용도
KR20210050041A (ko) * 2019-10-25 2021-05-07 한국화학연구원 리보조절인자를 이용한 바이러스 진단을 위한 fet 통합 센서 및 이의 이용 방법

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WO2014074648A2 (en) 2014-05-15
JP6130923B2 (ja) 2017-05-17
EP2917349A2 (en) 2015-09-16
CN104968786A (zh) 2015-10-07
EP3216870A1 (en) 2017-09-13
JP2017118881A (ja) 2017-07-06
CN108004238A (zh) 2018-05-08
US20150275203A1 (en) 2015-10-01
WO2014074648A3 (en) 2014-08-28
US20170175111A1 (en) 2017-06-22
EP2917349B1 (en) 2017-04-26
HK1212729A1 (en) 2016-06-17
US9550987B2 (en) 2017-01-24
JP2015533297A (ja) 2015-11-24
CN104968786B (zh) 2017-10-10

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