KR20150002801A - 섬유모세포 성장 인자 21 단백질의 치료 용도 - Google Patents

섬유모세포 성장 인자 21 단백질의 치료 용도 Download PDF

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Publication number
KR20150002801A
KR20150002801A KR1020147031701A KR20147031701A KR20150002801A KR 20150002801 A KR20150002801 A KR 20150002801A KR 1020147031701 A KR1020147031701 A KR 1020147031701A KR 20147031701 A KR20147031701 A KR 20147031701A KR 20150002801 A KR20150002801 A KR 20150002801A
Authority
KR
South Korea
Prior art keywords
seq
fgf21 protein
bone
fgf21
pro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020147031701A
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English (en)
Korean (ko)
Inventor
얀훼이 린다 마
아르만도 라파엘 이리자리 로비라
빈센트 루이스 레이놀즈
Original Assignee
일라이 릴리 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48483225&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20150002801(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 일라이 릴리 앤드 캄파니 filed Critical 일라이 릴리 앤드 캄파니
Publication of KR20150002801A publication Critical patent/KR20150002801A/ko
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020147031701A 2012-05-15 2013-05-09 섬유모세포 성장 인자 21 단백질의 치료 용도 Withdrawn KR20150002801A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261646974P 2012-05-15 2012-05-15
US61/646,974 2012-05-15
US201361786939P 2013-03-15 2013-03-15
US61/786,939 2013-03-15
PCT/US2013/040275 WO2013173158A1 (en) 2012-05-15 2013-05-09 Therapeutic uses of fibroblast growth factor 21 proteins

Publications (1)

Publication Number Publication Date
KR20150002801A true KR20150002801A (ko) 2015-01-07

Family

ID=48483225

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147031701A Withdrawn KR20150002801A (ko) 2012-05-15 2013-05-09 섬유모세포 성장 인자 21 단백질의 치료 용도

Country Status (21)

Country Link
US (1) US20150141335A1 (OSRAM)
EP (1) EP2852398A1 (OSRAM)
JP (1) JP2015522539A (OSRAM)
KR (1) KR20150002801A (OSRAM)
CN (1) CN104302311A (OSRAM)
AU (1) AU2013263188A1 (OSRAM)
BR (1) BR112014028413A2 (OSRAM)
CA (1) CA2869320A1 (OSRAM)
CL (1) CL2014002846A1 (OSRAM)
CO (1) CO7131381A2 (OSRAM)
EA (1) EA201491856A1 (OSRAM)
HK (1) HK1202800A1 (OSRAM)
IL (1) IL235482A0 (OSRAM)
MA (1) MA37506B1 (OSRAM)
MX (1) MX2014013913A (OSRAM)
PE (1) PE20142432A1 (OSRAM)
PH (1) PH12014502537A1 (OSRAM)
SG (1) SG11201407655TA (OSRAM)
TN (1) TN2014000409A1 (OSRAM)
WO (1) WO2013173158A1 (OSRAM)
ZA (1) ZA201407532B (OSRAM)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013006486A2 (en) 2011-07-01 2013-01-10 Ngm Biopharmaceuticals, Inc. Compositions, uses and methods for treatment of metabolic disorders and diseases
WO2014085365A2 (en) 2012-11-28 2014-06-05 Ngm Biopharmaceuticals, Inc. Compositions and methods for treatment of metabolic disorders and diseases
US9290557B2 (en) 2012-11-28 2016-03-22 Ngm Biopharmaceuticals, Inc. Compositions comprising variants and fusions of FGF19 polypeptides
US9273107B2 (en) 2012-12-27 2016-03-01 Ngm Biopharmaceuticals, Inc. Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
IL292303A (en) 2012-12-27 2022-06-01 Ngm Biopharmaceuticals Inc Methods for modulating bile acid homeostatsis and treatment of bile acid disorders and disease
SG11201602870YA (en) 2013-10-28 2016-05-30 Ngm Biopharmaceuticals Inc Cancer models and associated methods
PL3097122T3 (pl) 2014-01-24 2020-10-19 Ngm Biopharmaceuticals, Inc. Przeciwciała wiążące domenę 2 beta klotho oraz sposoby ich stosowania
WO2015183890A2 (en) 2014-05-28 2015-12-03 Ngm Biopharmaceuticals, Inc. Methods and compositions for the treatment of metabolic disorders and diseases
WO2015195509A2 (en) 2014-06-16 2015-12-23 Ngm Biopharmaceuticals, Inc. Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
WO2016039339A1 (ja) * 2014-09-08 2016-03-17 国立大学法人大阪大学 脱髄疾患の予防又は治療剤
WO2016065106A1 (en) 2014-10-23 2016-04-28 Ngm Biopharmaceuticals, Inc. Pharmaceutical compositions comprising peptide variants and methods of use thereof
WO2016073855A1 (en) 2014-11-07 2016-05-12 Ngm Biopharmaceuticals, Inc. Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders
US10800843B2 (en) 2015-07-29 2020-10-13 Ngm Biopharmaceuticals, Inc. Beta klotho-binding proteins
AU2016353988B2 (en) 2015-11-09 2019-09-26 Ngm Biopharmaceuticals, Inc. Methods for treatment of bile acid-related disorders
WO2018039557A1 (en) 2016-08-26 2018-03-01 Ngm Biopharmaceuticals, Inc. Methods of treating fibroblast growth factor 19-mediated cancers and tumors
CN108324928B (zh) * 2018-03-05 2020-09-08 哈尔滨医科大学 重组人成纤维细胞生长因子-5在促骨折愈合中的应用
EP3935075A4 (en) 2019-03-05 2023-01-18 Sunshine Lake Pharma Co., Ltd. POLYPEPTIDE MOLECULE AND APPLICATION THEREOF
WO2021139744A1 (en) 2020-01-11 2021-07-15 Beijing Ql Biopharmaceutical Co., Ltd. Conjugates of fusion proteins of glp-1 and fgf21
KR20240034235A (ko) 2021-07-14 2024-03-13 베이징 큐엘 바이오파마슈티컬 컴퍼니 리미티드 대사 장애를 위한 융합 폴리펩타이드

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101476472B1 (ko) * 2007-03-30 2015-01-05 암브룩스, 인코포레이티드 변형된 fgf-21 폴리펩티드 및 그 용도
AR087973A1 (es) * 2011-10-04 2014-04-30 Lilly Co Eli Variantes del factor 21 del crecimiento de fibroblastos

Also Published As

Publication number Publication date
CA2869320A1 (en) 2013-11-21
ZA201407532B (en) 2016-05-25
MX2014013913A (es) 2015-02-17
JP2015522539A (ja) 2015-08-06
US20150141335A1 (en) 2015-05-21
CL2014002846A1 (es) 2015-01-30
PE20142432A1 (es) 2015-01-22
TN2014000409A1 (en) 2015-12-21
PH12014502537A1 (en) 2015-01-21
SG11201407655TA (en) 2014-12-30
EA201491856A1 (ru) 2015-03-31
AU2013263188A1 (en) 2014-10-16
MA37506B1 (fr) 2017-03-31
CN104302311A (zh) 2015-01-21
MA37506A1 (fr) 2016-01-29
WO2013173158A1 (en) 2013-11-21
BR112014028413A2 (pt) 2017-11-07
CO7131381A2 (es) 2014-12-01
HK1202800A1 (en) 2015-10-09
IL235482A0 (en) 2014-12-31
EP2852398A1 (en) 2015-04-01

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A201 Request for examination
PA0105 International application

Patent event date: 20141112

Patent event code: PA01051R01D

Comment text: International Patent Application

PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20141112

Comment text: Request for Examination of Application

PG1501 Laying open of application
PC1202 Submission of document of withdrawal before decision of registration

Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment)

Patent event code: PC12021R01D

Patent event date: 20150604

WITB Written withdrawal of application