KR20140139563A - 캡슐화된 디에틸렌트리아민펜타아세테이트 입자들의 경구 전달을 위한 조성물 및 방법 - Google Patents

캡슐화된 디에틸렌트리아민펜타아세테이트 입자들의 경구 전달을 위한 조성물 및 방법 Download PDF

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Publication number
KR20140139563A
KR20140139563A KR1020147028955A KR20147028955A KR20140139563A KR 20140139563 A KR20140139563 A KR 20140139563A KR 1020147028955 A KR1020147028955 A KR 1020147028955A KR 20147028955 A KR20147028955 A KR 20147028955A KR 20140139563 A KR20140139563 A KR 20140139563A
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KR
South Korea
Prior art keywords
dtpa
composition
particles
less
average diameter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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KR1020147028955A
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English (en)
Korean (ko)
Inventor
제임스 데이비드 탈톤
Original Assignee
나노테라퓨틱스, 인코포레이티드
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Publication date
Application filed by 나노테라퓨틱스, 인코포레이티드 filed Critical 나노테라퓨틱스, 인코포레이티드
Publication of KR20140139563A publication Critical patent/KR20140139563A/ko
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/315—Zinc compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020147028955A 2012-03-22 2013-03-14 캡슐화된 디에틸렌트리아민펜타아세테이트 입자들의 경구 전달을 위한 조성물 및 방법 Ceased KR20140139563A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261614333P 2012-03-22 2012-03-22
US61/614,333 2012-03-22
US201361771873P 2013-03-03 2013-03-03
US61/771,873 2013-03-03
PCT/US2013/031336 WO2013142258A1 (en) 2012-03-22 2013-03-14 Compositions and methods for oral delivery of encapsulated diethylenetriaminepentaacetate particles

Publications (1)

Publication Number Publication Date
KR20140139563A true KR20140139563A (ko) 2014-12-05

Family

ID=48014341

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147028955A Ceased KR20140139563A (ko) 2012-03-22 2013-03-14 캡슐화된 디에틸렌트리아민펜타아세테이트 입자들의 경구 전달을 위한 조성물 및 방법

Country Status (8)

Country Link
US (1) US9040091B2 (https=)
EP (1) EP2827853A1 (https=)
JP (1) JP2015510935A (https=)
KR (1) KR20140139563A (https=)
AU (1) AU2013235491A1 (https=)
CA (1) CA2867701C (https=)
MX (1) MX2014011123A (https=)
WO (1) WO2013142258A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160135204A (ko) * 2014-02-18 2016-11-25 메데시스 파마 방사성 핵종 및 금속의 킬레이트제를 전달하기 위한 역-미셀계의 이용

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3002416C (en) 2015-10-23 2023-10-24 Vifor (International) Ag Benzimidazolyl derivatives for use as ferroportin inhibitors
JP2018052884A (ja) * 2016-09-29 2018-04-05 菊川　正 放射線核種キレート化剤を内包する経口投与剤
JOP20180036A1 (ar) 2017-04-18 2019-01-30 Vifor Int Ag أملاح لمثبطات فروبورتين جديدة
TW202102478A (zh) 2019-04-01 2021-01-16 瑞士商威佛（國際）股份有限公司 新穎的鐵螯合物
EP4719356A1 (en) 2023-06-05 2026-04-08 Nanopharmaceutics, Inc. Compositions and methods for oral delivery of sustained release crystalline prx-3140

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
NZ248813A (en) 1992-11-25 1995-06-27 Eastman Kodak Co Polymeric grinding media used in grinding pharmaceutical substances
TW384224B (en) 1994-05-25 2000-03-11 Nano Sys Llc Method of preparing submicron particles of a therapeutic or diagnostic agent
US5510118A (en) 1995-02-14 1996-04-23 Nanosystems Llc Process for preparing therapeutic compositions containing nanoparticles
UA76810C2 (uk) * 2001-12-10 2006-09-15 Мерк Енд Ко., Інк. Фармацевтична композиція антагоніста рецептора тахікініну у формі наночастинок
US7910086B1 (en) * 2005-01-04 2011-03-22 Gp Medical, Inc. Nanoparticles for protein drug delivery
JP2009500163A (ja) * 2005-07-07 2009-01-08 ナノセラピューティクス・インコーポレイテッド 粉末を製粉および調製する方法及びそれにより得られる組成物
JP4975047B2 (ja) * 2006-02-17 2012-07-11 エスアールアイ インターナショナル 放射性核種のキレート化のための経口ｄｔｐａ
WO2011133198A1 (en) * 2010-04-21 2011-10-27 Hosheng Tu A pharmaceutical composition of nanoparticles

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160135204A (ko) * 2014-02-18 2016-11-25 메데시스 파마 방사성 핵종 및 금속의 킬레이트제를 전달하기 위한 역-미셀계의 이용

Also Published As

Publication number Publication date
MX2014011123A (es) 2014-12-05
EP2827853A1 (en) 2015-01-28
US20130251815A1 (en) 2013-09-26
CA2867701A1 (en) 2013-09-26
AU2013235491A1 (en) 2014-09-11
JP2015510935A (ja) 2015-04-13
US9040091B2 (en) 2015-05-26
CA2867701C (en) 2020-10-27
WO2013142258A1 (en) 2013-09-26

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