KR20140130724A - 매트릭스 메탈로프로테이나제 9에 대한 항체 - Google Patents
매트릭스 메탈로프로테이나제 9에 대한 항체 Download PDFInfo
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- KR20140130724A KR20140130724A KR1020147026786A KR20147026786A KR20140130724A KR 20140130724 A KR20140130724 A KR 20140130724A KR 1020147026786 A KR1020147026786 A KR 1020147026786A KR 20147026786 A KR20147026786 A KR 20147026786A KR 20140130724 A KR20140130724 A KR 20140130724A
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96486—Metalloendopeptidases (3.4.24)
- G01N2333/96491—Metalloendopeptidases (3.4.24) with definite EC number
- G01N2333/96494—Matrix metalloproteases, e. g. 3.4.24.7
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Publications (1)
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| KR20140130724A true KR20140130724A (ko) | 2014-11-11 |
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Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011293125B2 (en) | 2010-08-27 | 2015-02-05 | Gilead Sciences, Inc. | Antibodies to matrix metalloproteinase 9 |
| CA2865501A1 (en) * | 2012-02-29 | 2013-09-06 | Gilead Biologics, Inc. | Antibodies to matrix metalloproteinase 9 |
| BR112014021477A2 (pt) | 2012-02-29 | 2018-06-12 | Gilead Sciences Inc | anticorpos para metaloproteinase de matriz 9 |
| CN106062001A (zh) * | 2014-02-27 | 2016-10-26 | 吉利德科学公司 | 基质金属蛋白酶9的抗体及其使用方法 |
| EP2985296A1 (en) * | 2014-08-13 | 2016-02-17 | Calypso Biotech SA | Antibodies specific for MMP9 |
| EP2985295A1 (en) * | 2014-08-13 | 2016-02-17 | Calypso Biotech SA | Antibodies specific for MMP9 |
| CN105037553B (zh) * | 2015-08-20 | 2018-04-17 | 内蒙古蒙元生物基因科技有限公司 | 一种能够检测癌症的免疫球蛋白 |
| JP2019513737A (ja) | 2016-04-08 | 2019-05-30 | ギリアード サイエンシーズ， インコーポレイテッド | がん、炎症性疾患および自己免疫疾患を処置するための組成物および方法 |
| US10326830B1 (en) * | 2016-09-02 | 2019-06-18 | Amazon Technologies, Inc. | Multipath tunneling to a service offered at several datacenters |
| US10894837B2 (en) | 2016-12-16 | 2021-01-19 | Université De Bordeaux | MMP9 inhibitors and uses thereof in the prevention or treatment of a depigmenting disorder |
| US10941178B2 (en) | 2017-03-17 | 2021-03-09 | Gilead Sciences, Inc. | Method of purifying an antibody |
| WO2019017338A1 (ja) | 2017-07-18 | 2019-01-24 | 第一三共株式会社 | 活性型ｍｍｐ－９結合ペプチド |
| CN110885375B (zh) * | 2019-12-20 | 2021-07-02 | 南京融捷康生物科技有限公司 | 特异性针对mmp-9蛋白锌离子结合结构域的单域抗体及产品与应用 |
| CN111785321B (zh) * | 2020-06-12 | 2022-04-05 | 浙江工业大学 | 一种基于深度卷积神经网络的dna绑定残基预测方法 |
| CN117327186B (zh) * | 2023-07-12 | 2024-03-12 | 北京达成生物科技有限公司 | 结合mmp3蛋白的双特异性抗体及其用途 |
| WO2025076280A1 (en) | 2023-10-05 | 2025-04-10 | Ashibio, Inc. | Methods and compositions for treating mmp-9 mediated disorders |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| KR100272077B1 (ko) | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| GB9022788D0 (en) | 1990-10-19 | 1990-12-05 | Cortecs Ltd | Pharmaceutical formulations |
| AU3178993A (en) | 1991-11-25 | 1993-06-28 | Enzon, Inc. | Multivalent antigen-binding proteins |
| DE60042487D1 (de) * | 1999-07-13 | 2009-08-13 | Univ Southern California | Methode und zusammensetzung zur angiogenese-inhibierung mit antagonisten gegen mmp-9 und beta1-integrine |
| CN1459505A (zh) * | 2002-05-21 | 2003-12-03 | 赵平 | 中国汉族人基质金属蛋白酶－9基因重构、表达、纯化及其医学应用 |
| EP1545611B1 (en) * | 2002-09-06 | 2016-11-09 | Alexion Pharmaceuticals, Inc. | Method of treatment of asthma using antibodies to complement component c5 |
| US8957187B2 (en) * | 2005-12-02 | 2015-02-17 | Genentech, Inc. | Binding polypeptides and uses thereof |
| WO2008154439A1 (en) * | 2007-06-08 | 2008-12-18 | Irm Llc | Methods and compositions for inducing apoptosis in cancer cells |
| US8008445B2 (en) * | 2008-03-03 | 2011-08-30 | Dyax Corp. | Metalloproteinase 9 binding proteins |
| JP2011517320A (ja) * | 2008-03-03 | 2011-06-02 | ダイアックス コーポレーション | メタロプロテアーゼ９結合タンパク質およびメタロプロテアーゼ２結合タンパク質 |
| EP2350305A4 (en) * | 2008-10-22 | 2013-03-06 | Dyax Corp | COMBINATION TREATMENTS WITH PROTEASE BINDING PROTEINS FOR INFLAMMATORY DISEASES |
| US20110286916A1 (en) * | 2008-11-20 | 2011-11-24 | Jose Miguel Aste-Amezaga | Generation and characterization of anti-notch antibodies for therapeutic and diagnostic use |
| WO2011092700A1 (en) * | 2010-01-27 | 2011-08-04 | Yeda Research And Development Co. Ltd. | Antibodies that inhibit metalloproteins |
| AU2011293125B2 (en) | 2010-08-27 | 2015-02-05 | Gilead Sciences, Inc. | Antibodies to matrix metalloproteinase 9 |
| BR112014021477A2 (pt) | 2012-02-29 | 2018-06-12 | Gilead Sciences Inc | anticorpos para metaloproteinase de matriz 9 |
| CA2865501A1 (en) | 2012-02-29 | 2013-09-06 | Gilead Biologics, Inc. | Antibodies to matrix metalloproteinase 9 |
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2012
- 2012-02-29 BR BR112014021477A patent/BR112014021477A2/pt not_active IP Right Cessation
- 2012-02-29 CN CN201280072749.6A patent/CN104395345A/zh active Pending
- 2012-02-29 JP JP2014559872A patent/JP6067756B2/ja not_active Expired - Fee Related
- 2012-02-29 IN IN8011DEN2014 patent/IN2014DN08011A/en unknown
- 2012-02-29 EP EP12708473.9A patent/EP2820048B1/en active Active
- 2012-02-29 HK HK15108571.3A patent/HK1208036A1/xx unknown
- 2012-02-29 KR KR1020147026786A patent/KR20140130724A/ko not_active Ceased
- 2012-02-29 WO PCT/US2012/027160 patent/WO2013130078A1/en not_active Ceased
- 2012-02-29 SG SG11201405305PA patent/SG11201405305PA/en unknown
- 2012-02-29 EA EA201491575A patent/EA201491575A1/ru unknown
- 2012-02-29 US US14/382,301 patent/US9550836B2/en active Active
- 2012-02-29 AP AP2014007907A patent/AP2014007907A0/xx unknown
- 2012-02-29 AU AU2012318302A patent/AU2012318302C1/en not_active Ceased
- 2012-02-29 CA CA2865530A patent/CA2865530C/en not_active Expired - Fee Related
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- 2012-02-29 MX MX2014010449A patent/MX2014010449A/es unknown
- 2012-02-29 MD MDA20140107A patent/MD20140107A2/ro not_active Application Discontinuation
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2014
- 2014-08-27 PH PH12014501931A patent/PH12014501931A1/en unknown
- 2014-08-27 ZA ZA2014/06319A patent/ZA201406319B/en unknown
- 2014-08-28 CL CL2014002282A patent/CL2014002282A1/es unknown
- 2014-08-29 CO CO14190943A patent/CO7061040A2/es unknown
- 2014-09-24 CR CR20140443A patent/CR20140443A/es unknown
- 2014-09-26 EC ECIEPI201420504A patent/ECSP14020504A/es unknown
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2015
- 2015-10-13 AU AU2015242967A patent/AU2015242967B2/en not_active Ceased
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2016
- 2016-12-12 US US15/376,232 patent/US20170183421A1/en not_active Abandoned
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2017
- 2017-08-16 AU AU2017216508A patent/AU2017216508B2/en not_active Ceased
- 2017-11-17 AU AU2017261626A patent/AU2017261626A1/en not_active Abandoned
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2019
- 2019-01-10 US US16/245,169 patent/US10800857B2/en active Active
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2020
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