KR20140058543A - 신규 피롤로 피리미딘 유도체 - Google Patents
신규 피롤로 피리미딘 유도체 Download PDFInfo
- Publication number
- KR20140058543A KR20140058543A KR1020147002986A KR20147002986A KR20140058543A KR 20140058543 A KR20140058543 A KR 20140058543A KR 1020147002986 A KR1020147002986 A KR 1020147002986A KR 20147002986 A KR20147002986 A KR 20147002986A KR 20140058543 A KR20140058543 A KR 20140058543A
- Authority
- KR
- South Korea
- Prior art keywords
- pyrimidin
- pyrrolo
- phenyl
- methyl
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- QKIUAMUSENSFQQ-UHFFFAOYSA-N dimethylazanide Chemical compound C[N-]C QKIUAMUSENSFQQ-UHFFFAOYSA-N 0.000 claims description 91
- 229910052739 hydrogen Inorganic materials 0.000 claims description 87
- 239000001257 hydrogen Substances 0.000 claims description 86
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- 229910052736 halogen Chemical group 0.000 claims description 62
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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| US201161505560P | 2011-07-08 | 2011-07-08 | |
| US61/505,560 | 2011-07-08 | ||
| PCT/IB2012/001699 WO2013008095A1 (en) | 2011-07-08 | 2012-07-07 | Novel pyrrolo pyrimidine derivatives |
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| KR20140058543A true KR20140058543A (ko) | 2014-05-14 |
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| KR1020147002986A Withdrawn KR20140058543A (ko) | 2011-07-08 | 2012-07-07 | 신규 피롤로 피리미딘 유도체 |
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| US (1) | US9233111B2 (https=) |
| EP (1) | EP2729466B1 (https=) |
| JP (1) | JP6145451B2 (https=) |
| KR (1) | KR20140058543A (https=) |
| CN (1) | CN103732596B (https=) |
| AU (1) | AU2012282229B2 (https=) |
| BR (1) | BR112014000314A2 (https=) |
| CA (1) | CA2841111A1 (https=) |
| EA (1) | EA201490229A1 (https=) |
| ES (1) | ES2548414T3 (https=) |
| MX (1) | MX2014000338A (https=) |
| WO (1) | WO2013008095A1 (https=) |
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| KR20180051220A (ko) * | 2016-11-08 | 2018-05-16 | 주식회사 대웅제약 | 신규한 피롤로피리미딘 유도체 및 이를 포함하는 약학적 조성물 |
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| MX391121B (es) | 2011-10-19 | 2025-03-19 | Pharmacyclics Llc | Uso de inhibidores de la tirosina cinasa de bruton (btk). |
| EP2780341B1 (en) | 2011-11-14 | 2019-02-13 | Chia Tai Tianqing Pharmaceutical Group Co.,Ltd | Kinase modulating compounds, compositions containing the same and use thereof |
-
2012
- 2012-07-07 ES ES12761655.5T patent/ES2548414T3/es active Active
- 2012-07-07 EA EA201490229A patent/EA201490229A1/ru unknown
- 2012-07-07 AU AU2012282229A patent/AU2012282229B2/en not_active Expired - Fee Related
- 2012-07-07 KR KR1020147002986A patent/KR20140058543A/ko not_active Withdrawn
- 2012-07-07 JP JP2014517980A patent/JP6145451B2/ja not_active Expired - Fee Related
- 2012-07-07 MX MX2014000338A patent/MX2014000338A/es unknown
- 2012-07-07 BR BR112014000314A patent/BR112014000314A2/pt not_active IP Right Cessation
- 2012-07-07 US US14/130,536 patent/US9233111B2/en not_active Expired - Fee Related
- 2012-07-07 CN CN201280033935.9A patent/CN103732596B/zh not_active Expired - Fee Related
- 2012-07-07 EP EP12761655.5A patent/EP2729466B1/en not_active Not-in-force
- 2012-07-07 WO PCT/IB2012/001699 patent/WO2013008095A1/en not_active Ceased
- 2012-07-07 CA CA2841111A patent/CA2841111A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20180051220A (ko) * | 2016-11-08 | 2018-05-16 | 주식회사 대웅제약 | 신규한 피롤로피리미딘 유도체 및 이를 포함하는 약학적 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| US9233111B2 (en) | 2016-01-12 |
| EP2729466B1 (en) | 2015-08-19 |
| ES2548414T3 (es) | 2015-10-16 |
| AU2012282229A1 (en) | 2014-01-16 |
| US20140243306A1 (en) | 2014-08-28 |
| EP2729466A1 (en) | 2014-05-14 |
| CA2841111A1 (en) | 2013-01-17 |
| JP2014520793A (ja) | 2014-08-25 |
| CN103732596B (zh) | 2016-06-01 |
| BR112014000314A2 (pt) | 2017-01-10 |
| JP6145451B2 (ja) | 2017-06-14 |
| CN103732596A (zh) | 2014-04-16 |
| MX2014000338A (es) | 2014-05-01 |
| WO2013008095A1 (en) | 2013-01-17 |
| AU2012282229B2 (en) | 2015-05-07 |
| EA201490229A1 (ru) | 2014-05-30 |
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