KR20140034898A - 헤테로시클릭 술폰아미드 유도체 - Google Patents

헤테로시클릭 술폰아미드 유도체 Download PDF

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Publication number
KR20140034898A
KR20140034898A KR1020147000283A KR20147000283A KR20140034898A KR 20140034898 A KR20140034898 A KR 20140034898A KR 1020147000283 A KR1020147000283 A KR 1020147000283A KR 20147000283 A KR20147000283 A KR 20147000283A KR 20140034898 A KR20140034898 A KR 20140034898A
Authority
KR
South Korea
Prior art keywords
compounds
fluoro
compound
difluoro
iodophenyl
Prior art date
Application number
KR1020147000283A
Other languages
English (en)
Korean (ko)
Inventor
라물루 포두투리
찬 왕
시앙린 자오
Original Assignee
노파르티스 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20140034898A publication Critical patent/KR20140034898A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
KR1020147000283A 2011-06-09 2012-06-06 헤테로시클릭 술폰아미드 유도체 KR20140034898A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN1634DE2011 2011-06-09
IN1634/DEL/11 2011-06-09
CN201210175145.6 2012-05-31
CN201210175145 2012-05-31
PCT/IB2012/052860 WO2012168884A1 (en) 2011-06-09 2012-06-06 Heterocyclic sulfonamide derivatives

Publications (1)

Publication Number Publication Date
KR20140034898A true KR20140034898A (ko) 2014-03-20

Family

ID=46384435

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147000283A KR20140034898A (ko) 2011-06-09 2012-06-06 헤테로시클릭 술폰아미드 유도체

Country Status (10)

Country Link
EP (1) EP2718276A1 (ru)
JP (1) JP2014517004A (ru)
KR (1) KR20140034898A (ru)
AU (1) AU2012265844A1 (ru)
BR (1) BR112013031201A2 (ru)
CA (1) CA2838029A1 (ru)
EA (1) EA201391820A1 (ru)
IN (1) IN2014DN00123A (ru)
MX (1) MX2013014398A (ru)
WO (1) WO2012168884A1 (ru)

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JPWO2013094546A1 (ja) * 2011-12-19 2015-04-27 住友化学株式会社 スルホン酸塩の製造方法
EP3251673A1 (en) 2012-12-13 2017-12-06 IP Gesellschaft für Management mbH Combination therapy comprising a cdk4/6 inhibitor and a pi3k inhibitor for use in the treatment of cancer
CN104886052B (zh) * 2015-06-02 2016-08-31 吉林省八达农药有限公司 一种环丙磺酰胺的应用
TW201906832A (zh) * 2017-05-25 2019-02-16 美商亞瑞克西斯製藥公司 用於癌症治療之化合物及其使用方法
WO2019183385A1 (en) * 2018-03-22 2019-09-26 University Of Rochester Mapk/erk inhibition for ovarian and other cancers

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Also Published As

Publication number Publication date
BR112013031201A2 (pt) 2017-01-31
JP2014517004A (ja) 2014-07-17
CA2838029A1 (en) 2012-12-13
IN2014DN00123A (ru) 2015-05-22
WO2012168884A1 (en) 2012-12-13
EP2718276A1 (en) 2014-04-16
AU2012265844A1 (en) 2013-05-02
MX2013014398A (es) 2014-03-21
EA201391820A1 (ru) 2014-12-30

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