KR20140019334A - 심장 질환의 치료와 관련된 정맥 자극을 조절하기 위한 (s)-에스모롤의 용도 - Google Patents

심장 질환의 치료와 관련된 정맥 자극을 조절하기 위한 (s)-에스모롤의 용도 Download PDF

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Publication number
KR20140019334A
KR20140019334A KR1020137022490A KR20137022490A KR20140019334A KR 20140019334 A KR20140019334 A KR 20140019334A KR 1020137022490 A KR1020137022490 A KR 1020137022490A KR 20137022490 A KR20137022490 A KR 20137022490A KR 20140019334 A KR20140019334 A KR 20140019334A
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KR
South Korea
Prior art keywords
subject
composition
isopropylamino
propoxy
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020137022490A
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English (en)
Korean (ko)
Inventor
제롬 에이치 개스
제프 맥키
바렛 래비노
Original Assignee
백스터 인터내셔널 인코포레이티드
박스터 헬쓰케어 에스에이
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Application filed by 백스터 인터내셔널 인코포레이티드, 박스터 헬쓰케어 에스에이 filed Critical 백스터 인터내셔널 인코포레이티드
Publication of KR20140019334A publication Critical patent/KR20140019334A/ko
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020137022490A 2011-01-27 2012-01-26 심장 질환의 치료와 관련된 정맥 자극을 조절하기 위한 (s)-에스모롤의 용도 Withdrawn KR20140019334A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161436995P 2011-01-27 2011-01-27
US61/436,995 2011-01-27
PCT/US2012/022679 WO2012103305A1 (en) 2011-01-27 2012-01-26 Use of (s) - esmolol for controlling venous irritation associated with the treatment of a cardiac disorder

Publications (1)

Publication Number Publication Date
KR20140019334A true KR20140019334A (ko) 2014-02-14

Family

ID=45567140

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020137022490A Withdrawn KR20140019334A (ko) 2011-01-27 2012-01-26 심장 질환의 치료와 관련된 정맥 자극을 조절하기 위한 (s)-에스모롤의 용도

Country Status (10)

Country Link
US (1) US8829047B2 (enExample)
EP (1) EP2667866B1 (enExample)
JP (1) JP2014511365A (enExample)
KR (1) KR20140019334A (enExample)
CN (1) CN103347513A (enExample)
AU (1) AU2012211309B2 (enExample)
BR (1) BR112013018598A2 (enExample)
CA (1) CA2825716A1 (enExample)
MX (1) MX2013008715A (enExample)
WO (1) WO2012103305A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012211318C1 (en) 2011-01-27 2016-08-04 Baxter Healthcare S.A. Methods of treating tachycardia and/or controlling heart rate while minimizing and/or controlling hypotension
US10307167B2 (en) 2012-12-14 2019-06-04 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10314594B2 (en) 2012-12-14 2019-06-11 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10813630B2 (en) 2011-08-09 2020-10-27 Corquest Medical, Inc. Closure system for atrial wall
US20140142689A1 (en) 2012-11-21 2014-05-22 Didier De Canniere Device and method of treating heart valve malfunction
US9566443B2 (en) 2013-11-26 2017-02-14 Corquest Medical, Inc. System for treating heart valve malfunction including mitral regurgitation
US10842626B2 (en) 2014-12-09 2020-11-24 Didier De Canniere Intracardiac device to correct mitral regurgitation
EP4490042A4 (en) 2022-03-08 2026-03-04 Equashield Medical Ltd FLUID TRANSFER STATION IN A ROBOTIC PHARMACEUTICAL PREPARATION SYSTEM

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU575153B2 (en) 1984-04-09 1988-07-21 Du Pont Merck Pharmaceutical Company, The Pharmaceutical compositions and method for treatment for prophylaxis of cardiac disorders
JPS63502585A (ja) 1985-12-04 1988-09-29 ザ デュポン メルク ファーマシュウティカル カンパニー アリルオキシプロパノ−ルアミン類及びアリルエタノ−ルアミン類の合成法
AU607437B2 (en) 1986-09-02 1991-03-07 Du Pont Pharmaceuticals Company Resolution of dl-methyl 3-(4-(2-hydroxy-3-isopropylamino) propoxy)phenylpropionate((dl-esmolol))
US4857552A (en) 1988-06-08 1989-08-15 E. I. Du Pont De Nemours And Co. Stable pharmaceutical composition
US5849843A (en) 1993-11-16 1998-12-15 Baxter International Inc. Polymeric compositions for medical packaging and devices
US5998019A (en) 1993-11-16 1999-12-07 Baxter International Inc. Multi-layered polymer structure for medical products
US5977409A (en) * 1997-04-15 1999-11-02 University Of Toledo Method of using α-substituted benzylamine chiral auxiliary synthetic reagents
TWI277414B (en) * 2001-01-12 2007-04-01 Baxter Int Esmolol formulation
US6310094B1 (en) * 2001-01-12 2001-10-30 Baxter International Inc. Ready-to-use esmolol solution
ATE533509T1 (de) 2003-08-08 2011-12-15 Ono Pharmaceutical Co Herzverlangsamender arzneistoff mit beta-blockern mit kurzzeitwirkung als wirkstoff
US20080293814A1 (en) * 2007-05-22 2008-11-27 Deepak Tiwari Concentrate esmolol
CN101323580A (zh) 2008-07-25 2008-12-17 河北科技大学 手性芳氧丙醇胺类化合物及其盐的合成方法
CN101881755B (zh) 2009-05-04 2013-05-29 南京海辰药业有限公司 通过高效液相色谱法检测盐酸艾司洛尔光学异构体的方法
CN101891636A (zh) 2009-05-21 2010-11-24 南京海辰药业有限公司 制备盐酸艾司洛尔光学异构体的新方法
CN102106846A (zh) 2009-12-23 2011-06-29 南京海辰药业有限公司 左旋盐酸艾司洛尔药物组合物及其制备方法
AU2012211318C1 (en) 2011-01-27 2016-08-04 Baxter Healthcare S.A. Methods of treating tachycardia and/or controlling heart rate while minimizing and/or controlling hypotension

Also Published As

Publication number Publication date
BR112013018598A2 (pt) 2016-10-18
EP2667866A1 (en) 2013-12-04
MX2013008715A (es) 2013-08-29
JP2014511365A (ja) 2014-05-15
US20120277309A1 (en) 2012-11-01
AU2012211309B2 (en) 2014-10-09
WO2012103305A1 (en) 2012-08-02
CA2825716A1 (en) 2012-08-02
CN103347513A (zh) 2013-10-09
US8829047B2 (en) 2014-09-09
AU2012211309A1 (en) 2013-05-02
EP2667866B1 (en) 2015-05-20

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20130826

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid