AU2012211309B2 - Use of (S) - esmolol for controlling venous irritation associated with the treatment of a cardiac disorder - Google Patents
Use of (S) - esmolol for controlling venous irritation associated with the treatment of a cardiac disorder Download PDFInfo
- Publication number
- AU2012211309B2 AU2012211309B2 AU2012211309A AU2012211309A AU2012211309B2 AU 2012211309 B2 AU2012211309 B2 AU 2012211309B2 AU 2012211309 A AU2012211309 A AU 2012211309A AU 2012211309 A AU2012211309 A AU 2012211309A AU 2012211309 B2 AU2012211309 B2 AU 2012211309B2
- Authority
- AU
- Australia
- Prior art keywords
- subject
- hydroxy
- phenylpropionate
- composition
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 208000020446 Cardiac disease Diseases 0.000 title claims abstract description 10
- 208000019622 heart disease Diseases 0.000 title claims abstract description 10
- 230000007794 irritation Effects 0.000 title claims description 82
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- 125000002572 propoxy group Chemical group [*]OC([H])([H])C(C([H])([H])[H])([H])[H] 0.000 claims abstract description 113
- 150000003839 salts Chemical class 0.000 claims abstract description 111
- DYUMLJSJISTVPV-UHFFFAOYSA-N phenyl propanoate Chemical compound CCC(=O)OC1=CC=CC=C1 DYUMLJSJISTVPV-UHFFFAOYSA-N 0.000 claims abstract description 92
- 238000000034 method Methods 0.000 claims abstract description 74
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- GXLJZLBKWSJXFP-UHFFFAOYSA-N phenyl propanoate;hydrochloride Chemical compound Cl.CCC(=O)OC1=CC=CC=C1 GXLJZLBKWSJXFP-UHFFFAOYSA-N 0.000 claims abstract description 23
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161436995P | 2011-01-27 | 2011-01-27 | |
| US61/436,995 | 2011-01-27 | ||
| PCT/US2012/022679 WO2012103305A1 (en) | 2011-01-27 | 2012-01-26 | Use of (s) - esmolol for controlling venous irritation associated with the treatment of a cardiac disorder |
Publications (2)
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| AU2012211309A1 AU2012211309A1 (en) | 2013-05-02 |
| AU2012211309B2 true AU2012211309B2 (en) | 2014-10-09 |
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| US (1) | US8829047B2 (enExample) |
| EP (1) | EP2667866B1 (enExample) |
| JP (1) | JP2014511365A (enExample) |
| KR (1) | KR20140019334A (enExample) |
| CN (1) | CN103347513A (enExample) |
| AU (1) | AU2012211309B2 (enExample) |
| BR (1) | BR112013018598A2 (enExample) |
| CA (1) | CA2825716A1 (enExample) |
| MX (1) | MX2013008715A (enExample) |
| WO (1) | WO2012103305A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8686036B2 (en) | 2011-01-27 | 2014-04-01 | Baxter International Inc. | Methods of controlling heart rate while minimizing and/or controlling hypotension |
| US10314594B2 (en) | 2012-12-14 | 2019-06-11 | Corquest Medical, Inc. | Assembly and method for left atrial appendage occlusion |
| US10813630B2 (en) | 2011-08-09 | 2020-10-27 | Corquest Medical, Inc. | Closure system for atrial wall |
| US10307167B2 (en) | 2012-12-14 | 2019-06-04 | Corquest Medical, Inc. | Assembly and method for left atrial appendage occlusion |
| US20140142689A1 (en) | 2012-11-21 | 2014-05-22 | Didier De Canniere | Device and method of treating heart valve malfunction |
| US9566443B2 (en) | 2013-11-26 | 2017-02-14 | Corquest Medical, Inc. | System for treating heart valve malfunction including mitral regurgitation |
| US10842626B2 (en) | 2014-12-09 | 2020-11-24 | Didier De Canniere | Intracardiac device to correct mitral regurgitation |
| CA3244889A1 (en) | 2022-03-08 | 2023-09-14 | Equashield Medical Ltd | FLUID TRANSFER STATION IN A ROBOTIC PHARMACEUTICAL PREPARATION SYSTEM |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5977409A (en) * | 1997-04-15 | 1999-11-02 | University Of Toledo | Method of using α-substituted benzylamine chiral auxiliary synthetic reagents |
| WO2002076446A1 (en) * | 2001-01-12 | 2002-10-03 | Baxter International Inc. | Esmolol formulation |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0720861B2 (ja) | 1984-04-09 | 1995-03-08 | ザ デュポン マーク ファーマソウテイカル カンパニー | 心臓障害の処置または予防用の医薬組成物および方法 |
| EP0248879A4 (en) * | 1985-12-04 | 1990-02-26 | Du Pont | PRODUCTION OF ARYLOXYPROPANOLAMINES AND ARYLÄTHANOLAMINES. |
| WO1988001614A1 (en) | 1986-09-02 | 1988-03-10 | E.I. Du Pont De Nemours And Company | RESOLUTION OF dl-METHYL 3-[4-(2-HYDROXY-3-ISOPROPYLAMINO)PROPOXY]PHENYLPROPIONATE [(dl-ESMOLOL)] |
| US4857552A (en) | 1988-06-08 | 1989-08-15 | E. I. Du Pont De Nemours And Co. | Stable pharmaceutical composition |
| US5998019A (en) | 1993-11-16 | 1999-12-07 | Baxter International Inc. | Multi-layered polymer structure for medical products |
| US5849843A (en) | 1993-11-16 | 1998-12-15 | Baxter International Inc. | Polymeric compositions for medical packaging and devices |
| US6310094B1 (en) * | 2001-01-12 | 2001-10-30 | Baxter International Inc. | Ready-to-use esmolol solution |
| WO2005014042A1 (ja) | 2003-08-08 | 2005-02-17 | Ono Pharmaceutical Co., Ltd. | 短時間型β遮断薬を有効成分とする心拍数減少剤 |
| US20080293814A1 (en) * | 2007-05-22 | 2008-11-27 | Deepak Tiwari | Concentrate esmolol |
| CN101323580A (zh) | 2008-07-25 | 2008-12-17 | 河北科技大学 | 手性芳氧丙醇胺类化合物及其盐的合成方法 |
| CN101881755B (zh) | 2009-05-04 | 2013-05-29 | 南京海辰药业有限公司 | 通过高效液相色谱法检测盐酸艾司洛尔光学异构体的方法 |
| CN101891636A (zh) | 2009-05-21 | 2010-11-24 | 南京海辰药业有限公司 | 制备盐酸艾司洛尔光学异构体的新方法 |
| CN102106846A (zh) | 2009-12-23 | 2011-06-29 | 南京海辰药业有限公司 | 左旋盐酸艾司洛尔药物组合物及其制备方法 |
| US8686036B2 (en) | 2011-01-27 | 2014-04-01 | Baxter International Inc. | Methods of controlling heart rate while minimizing and/or controlling hypotension |
-
2012
- 2012-01-26 EP EP20120702940 patent/EP2667866B1/en not_active Not-in-force
- 2012-01-26 CA CA2825716A patent/CA2825716A1/en not_active Abandoned
- 2012-01-26 MX MX2013008715A patent/MX2013008715A/es active IP Right Grant
- 2012-01-26 JP JP2013551325A patent/JP2014511365A/ja not_active Withdrawn
- 2012-01-26 KR KR1020137022490A patent/KR20140019334A/ko not_active Withdrawn
- 2012-01-26 BR BR112013018598A patent/BR112013018598A2/pt not_active IP Right Cessation
- 2012-01-26 WO PCT/US2012/022679 patent/WO2012103305A1/en not_active Ceased
- 2012-01-26 US US13/358,949 patent/US8829047B2/en active Active
- 2012-01-26 AU AU2012211309A patent/AU2012211309B2/en not_active Ceased
- 2012-01-26 CN CN2012800067439A patent/CN103347513A/zh active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5977409A (en) * | 1997-04-15 | 1999-11-02 | University Of Toledo | Method of using α-substituted benzylamine chiral auxiliary synthetic reagents |
| WO2002076446A1 (en) * | 2001-01-12 | 2002-10-03 | Baxter International Inc. | Esmolol formulation |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012103305A1 (en) | 2012-08-02 |
| JP2014511365A (ja) | 2014-05-15 |
| BR112013018598A2 (pt) | 2016-10-18 |
| KR20140019334A (ko) | 2014-02-14 |
| CN103347513A (zh) | 2013-10-09 |
| US8829047B2 (en) | 2014-09-09 |
| MX2013008715A (es) | 2013-08-29 |
| US20120277309A1 (en) | 2012-11-01 |
| CA2825716A1 (en) | 2012-08-02 |
| AU2012211309A1 (en) | 2013-05-02 |
| EP2667866A1 (en) | 2013-12-04 |
| EP2667866B1 (en) | 2015-05-20 |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |