KR20130112571A - Manufacture method of transparent cinnamon extract and an insecticide ingredient using thereof - Google Patents

Abstract

PURPOSE: A method for preparing a transparent cinnamon extract and an insecticidal composition thereby are provided to obtain a fresh indoor environment regardless of a place or a condition through spraying the transparent cinnamon extract. CONSTITUTION: An insecticidal composition contains a transparent cinnamon extract. A method for preparing the extract comprises the steps of: heating/eluting cinnamon bark by hot water extraction using water or a mixture solvent containing water and 25-45 volume% of ethanol; separating the extract into solids and the solvent; and distilling the solvent by simple batch distillation or fractional distillation.

Description

Manufacturing method of transparent cinnamon extract and an insecticide ingredient using

The present invention solids of cinnamon bark present in the water during the extraction process through a solvent extraction step and a filtration step of heating and eluting cinnamon used as a spice of sikhae, a traditional drink of Korea by water or a mixed solvent of water and alcohol Separating the extraction solvent and the extraction solvent provided in the above step to obtain a transparent cinnamon extract containing the active ingredient of cinnamon through the distillation process, by using it for the removal of mosquitoes and insecticides of house ticks The present invention is to provide a cinnamon extract that is applied to prevent the contamination by spraying on.

The cinnamon extract provided herein prevents access to mosquitoes and flies in the summer without harm to the human body, sprays on clothes or bedding, and is effective in killing ticks of the house, regardless of places or environments such as indoors or outdoors. It is an invention that can be provided as a spray solvent for insects without providing a healthy and comfortable indoor environment.

Cinnamon is one of the world's three major spices along with pepper and cloves. It is dried cinnamon and liver of the cinnamon tree belonging to the camphor tree, and has been used as a flavoring agent for confectionery and beverages since ancient times. The frequency of use is high.

Cinnamon is a spice which is generally superior to nutritional ingredients. It is reported that Carvacrol among the essential components of cinnamon inhibits the growth of Escherichia coli and Staphylococus aureus, Is used as a food additive in addition to the herbal medicine effect, and it is known that it is effective for preventing tooth decay by insecticidal action against ticks and house worms.

As a prior art for providing an insect repellent using the extract of cinnamon as described in Korean Patent Laid-Open Publication No. 2011-0107513, deodorizing functions such as pine oil, cypress oil, eucalyptus, lavender, lemon, apple, cinnamon, camphor tree and cedar Antimicrobial deodorant for distilling and purifying excellent natural plants to extract essential oil in the form of oil, diluting the extracted oil in essential oil by distillation by steam distillation process to have the pyrophoric property, and then aging the processed essential oil to produce The production method is limited, the invention has the advantage of providing a pesticide harmless to the human body by using a natural plant, but the extract is provided in the form of an oil, any method without applying treatment with an emulsifier Can not be mixed at all, and oil-based insect repellents and deodorants When sprayed on a silver place, there is a problem that can not be applied to the use of the present application in that there is a possibility of harming the aesthetics by the occurrence of grease.

Korean Laid-Open Patent Publication No. 2011-0045440 discloses a liquid extract 55-60% by weight of the active ingredient extracted from Artemisia spp. Having a moisture content of 1-3% by weight, and a liquid extract 10-15% by weight of cinnamon. %, Palm oil 20-30% by weight, jojoba oil (Jojoba oil) 5% by weight, 1 to 2% by weight of the super-aging maturation solution has been proposed as a mosquito repellent composition, the invention is the human body It is harmless to mosquitoes and has an advantage of being able to combat mosquitoes by environmentally friendly methods as it shows excellent repellent activity against mosquitoes, but the present invention extracts the stock solution from mugwort and cinnamon and mixes another natural oil to mosquito repellent As it is applied, not only has a unique color of natural products, but also consists of oil-based mosquito repellent composition, so the use and technical composition of the present cinnamon extract is completely different.

In addition, Korean Laid-Open Patent Publication No. 2010-0110919 proposes a disposable absorbent article to which an encapsulated natural plant extract is applied, which exhibits an insect repellent effect. It has the advantage that it can be released for a long time to maintain the insect repellent effect, but when used in the purpose of spraying as the present application has a problem that may be stained by the inherent color of the natural product and the present invention is to include a natural plant extract in a disposable absorbent article On the other hand, the present application is a transparent liquid cinnamon extract and a method using the same for the insect repellent and deodorizing effect is completely different in the technical configuration.

Korean Laid-Open Patent Publication No. 2010-0058032 discloses the prevention of Parkinson's disease, which contains an extract of Cinnamomum cassia, a fraction thereof or a trans-cinnamaldehyde isolated from cinnamon as an active ingredient. And propose a therapeutic composition, the invention cited in the present invention for the prevention and treatment of Parkinson's disease is a composition that can be drinking irrespective of the color of the cinnamon tree extract to obtain a transparent liquid cinnamon extract in the present invention It is different from the purpose, and also in the technical configuration.

In Korean Patent Publication No. 2009-0110038, it is composed of 25 ~ 35% by weight, 15 ~ 25% by weight of cinnamon bark and 5 ~ 15% by weight of red ginseng, mixed, and made by the extraction step by a mixed solvent A method for preparing a composition has been proposed, and the present invention is a technique for obtaining a natural composition of mosquitoes by extracting an active ingredient by a solvent extraction method after mixing natural products in an appropriate ratio. When sprayed for the purpose of insect repellent present in each of these will leave stains on clean clothing or bedding, which can not be used for the purposes of the present application.

In Korean Patent Publication No. 2009-0022941, DEET (N, N-diethyl) is applied to mosquito repellent for skin application to prevent humans or livestock from accessing mosquitoes for a long time, and to provide antibacterial activity to human skin or animal hair epidermis. -m-toluamide) or a mosquito repellent by the method of encapsulating the distilled tomato distillate and a method for producing the same, the mosquito repellent and red color by the composition of DEET and tomato, which is a mosquito dislike Although there are similar parts to the present application in the part which constitutes the transparent mosquito repellent by distillation method, the present invention proposes the transparent mosquito repellent of tomato, whereas the present suggests the transparent cinnamon extract. As a result, the manufacturing process may be different, and as a result, the technical configuration may be different.

As described above, cinnamon is a natural product that can be used in the food field, and it is harmless to the human body and has an effective herbal and insecticidal effect. Therefore, it can be used as an environmentally friendly insect repellent. Although cinnamon extract eluted in hot water is used, cinnamon eluate has a brown color peculiar to natural products. Therefore, cinnamon extract eluted in a solvent is used to kill house ticks that inhabit bedding or walls, or to enter mosquitoes on human skin. In order to prevent clothing, bedding, wall, skin, etc. when sprayed with a stain of brown foreign matters had a problem that you have to wash immediately.

The present application is made in view of all the problems of the existing known technology investigated in the background art, brown cinnamon extracted with a solvent to combat the ticks inhabiting clothes or bedding or walls or mosquitoes entering the room When spraying the extract, the effective ingredient of cinnamon is not compromised since the solid brown foreign matter can cause stains on clothing, bedding and walls after the solvent has evaporated, which can damage the appearance of clean clothing, bedding and walls. The invention started with the problem of removing the colored component in the extract to provide a repellent of the transparent liquid cinnamon extract component.

The present application provides a transparent cinnamon extract that removes the colored material contained in the cinnamon extract without damaging the active ingredient of cinnamon to prevent mosquito access to the human body by the active ingredient of cinnamon or spray to remove house mites contaminated with indoor space. It is an object of the invention to provide a natural insect repellent sprayed by means.

We use brown cinnamon extract to obtain clear natural insect repellent by a specific distillation method to prevent dusting of mosquitoes approaching the human body or to remove dust mites inhabiting indoor bedding, clothing and walls. It is an object of the present invention to provide an environmentally friendly natural insect repellent and a spray / spray method that does not cause brown stains on clothes, bedding and walls when sprayed.

In the present application, cinnamon not only functions as a spice with excellent functionality, but also can be used as a beverage, herbal medicine, and pest control agent because it has oriental medicine effect and insecticidal effect, but sprays the extract solution of cinnamon onto clothing, wallpaper and skin surface. In order to solve the problem of visual discomfort because the brown cinnamon extract is contaminated with clean clothes, bedding, and the surface of the wall with brown foreign matter, the active ingredient of cinnamon is preserved and colored components are removed. It is an invention of the technical idea to provide a method for obtaining a transparent cinnamon extract by the classification process and a natural insect repellent using the same.

The present invention is a means for obtaining a transparent cinnamon extract while preserving the active ingredient of cinnamon, solvent extraction step of heating and eluting cinnamon bark with a solvent containing water in order to extract the active ingredient of cinnamon in the liquid phase, and during the extraction process A solid cinnamon extract containing an active ingredient of cinnamon can be obtained through a solid-liquid separation step of separating the solid content of the cinnamon bark and the extraction solvent present in water, and an extraction solvent having undergone the solid-liquid separation step. Check the completed invention.

The technical idea of the present application is applied to obtain the brown cinnamon extract as a transparent cinnamon extract is that the colored extract extracted from the bark of evergreen cassia of all camphoraceae can be obtained the same as the technical idea of the present application .

The solvent extraction step for extracting the active ingredient of cinnamon in the liquid phase is a method for extracting an active ingredient that can provide insect repellent effect by dissolving the solid of the cinnamon skin using a liquid solvent, the solvent is included The cinnamon shell is added to the reactor, and the extraction process may be performed by a hot water extraction method.

Solvent for extracting the active ingredient of cinnamon of the present invention can increase the extraction efficiency according to the polarity (Porarity) of the active ingredient is used alone or water and ethanol of 25 ~ 45 v% concentration range It is possible to use a mixed solvent included, wherein the hot water extraction method is preferably extracted in the range of 40 to 125 ℃ with a pressure of 2.5 kgf / cm ² at normal pressure.

In case of performing hot water extraction by atmospheric pressure, the volatile active ingredient of cinnamon is lost during the extraction process, and the insect repellent effect may be lowered. Therefore, in order to prevent this, it is preferable to apply a condenser to the outlet of the reactor. When hot water extraction is performed, it is unlikely that a condenser will be installed since the possibility of volatile active ingredient being discharged to the outside is unlikely.

The step of separating the solids and the extraction solvent of the cinnamon bark existing in the water during the extraction process is not particularly limited, but if the extracted solvent contains a large amount of solids of the cinnamon bark by the solids contained in the solvent during the distillation process It is preferable to use a physical filtration method as much as possible to obtain a brown extract having no solid content because it is inconvenient to wash the extraction reactor afterwards because it adheres to the inner surface of the evaporation vessel.

The distillation step is the most important experimental operation for purifying a liquid containing impurities. It is a means of separating each active ingredient from a mixture by using a difference in volatility, and brown cinnamon obtained by a method of extracting hot water present in a liquid phase. The extract is an important process to obtain a transparent cinnamon extract without damaging or losing the active ingredient of cinnamon.

The distillation method applicable herein is a simple batch distillation or small glass eggs which can directly cool water vapor generated by heating brown cinnamon extraction under pressure conditions of atmospheric pressure to reduced pressure to obtain a transparent cinnamon extract. The method of fractional distillation, in which the evaporation and liquefaction of the mixture is repeated and distilled by using the temperature change according to the height of the fractional distillation tube installed on the filled reactor, can be used. It is preferable to use a distillation method by a liquid ash distillation method of normal pressure or reduced pressure as a means having a simple and economical in order to obtain a.

Although the cinnamon extract has an insect repellent effect such as house mites and mosquito repellents, the present invention provides an effect of improving and eliminating the problem that the cinnamon extract has a brown color, so that stains such as clean clothes, beddings, and walls cannot be used. .

The present application provides a transparent cinnamon extract without damaging or losing the active ingredient of cinnamon, which is intended to prevent mosquito access to the human body or to combat house ticks contaminated with indoor space. It provides an eco-friendly, high-value natural insect repellent of the type that does not cause brown stains even when sprayed on all object surfaces, thereby maximizing the environmental and health benefits.

1 is a photographic example applied to obtain a transparent cinnamon extract using a rotary evaporator in a brown cinnamon extract in an embodiment to which the technical idea of the present application is applied.

Prior to describing the embodiments of the invention for embodying the technical idea of the present application by way of example, the terms or words used in the specification or claims of the present application shall not be construed as being limited to a common or dictionary meaning, It should be understood that the scope of protection of the present application should be interpreted as meanings and concepts corresponding to the technical spirit of the present invention, and the embodiments described herein may have various equivalents and modifications that can variously substitute them. will be.

Hereinafter, the present invention was applied to the present invention, and the cinnamon bark was compared to the result of applying the brown cinnamon extract eluted by the hot water extraction method to obtain a transparent cinnamon extract by distillation means.

Example 1 (Hot water extraction process of cinnamon 1: atmospheric mixed solvent extraction)

In order to extract the active ingredient of cinnamon after purchasing cinnamon peel in the traditional market, various hot water extraction methods were used and compared.

As a solvent for extracting the active ingredient of cinnamon, a mixed solvent in which ethanol is 30 v% was used. At this time, cinnamon was added 35 parts by weight of ground cinnamon peel based on 100 parts by weight of the mixed solvent.

A round flask containing an extract sample is mounted on a heating mantle, a condenser is mounted on the spout of a round flask, and after cooling water flows, it is extracted for 6 hours at atmospheric pressure of 65 ° C. and cooled. After filtration to prepare a brown cinnamon extract.

Example 2 (thermal water extraction process of cinnamon 2: atmospheric pressure mixed solvent extraction by Soxhlet extraction device)

As a solvent for extracting the active ingredient of cinnamon, a mixed solvent in which ethanol became 30 v% was used.

First, a round flask is mounted on the mantle, a Soxhlet is installed in the spout of the round flask, and after cooling water flows, it is extracted for 6 hours at a normal pressure of 65 ° C., and then filtered and then brown cinnamon extract. Was prepared.

At this time, cinnamon was refluxed after measuring 35 parts by weight of ground cinnamon peel in a thimble based on 100 parts by weight of the mixed solvent.

Example 3 (Hot Water Extraction Step 3: Extraction of Pressurized Hot Water Using Water Solvent)

Distilled water was used as a solvent for extracting the active ingredient of cinnamon. At this time, based on 100 parts by weight of distilled water, 35 parts by weight of crushed cinnamon peel was put in a pressure cooker, heated for 1 hour, extracted, and cooled. After filtration to prepare a brown cinnamon extract.

Example 4 (Hot water extraction process of cinnamon 4: Atmospheric hot water extraction using a water solvent)

Distilled water was used as a solvent for extracting the active ingredient of cinnamon, and cinnamon was added 35 parts by weight of ground cinnamon peel to the round flask based on 100 parts by weight of distilled water.

A round flask containing an extract sample is mounted on a heating mantle, a condenser is mounted on the spout of a round flask, and after cooling water flows, it is extracted for 6 hours at 100 ° C and cooled. After filtration to prepare a brown cinnamon extract.

Examples 5 to 8 (Decompression distillation using a rotary evaporator)

Adjust the temperature of the water bath of the rotary evaporation concentrator to 70 ° C, transfer the brown cinnamon extract made in Examples 1 to 4 to the round flask, install it in the rotary evaporation concentrator, and rotate and reduce the pressure while operating the cooling water. The distillate by the evaporation concentrator was obtained.

Examples 9-12 (atmospheric distillation using a simple batch distillation method)

The brown cinnamon extract made in Examples 1 to 4 was transferred to a round flask, mounted on a mantle, and a condenser was collected through an elbow to collect an active ingredient of volatilized cinnamon from the outside. After adjusting so that it might be below a spout, it boiled at 100 degreeC and obtained the distillate by the liquid ash distillation method under the conditions of normal pressure.

Cinnamon distillates made in Examples 5-12 and cinnamon made in Examples 1 to 4 to check brown stains on the surface of the subjects when sprayed onto the subjects and dried after using the prepared cinnamon extracts as insect repellents. Each extract was sprayed uniformly onto white copy paper and white cloth using a household sprayer, and then dried, and the color was checked by the sensory method.

A total of 13 persons (8 males and 6 females) participated in the sensory test to distinguish the brown color, and the mean age was 32.6 years.

Comparative Examples 1 to 4

The cinnamon extract prepared in Examples 1 to 4 was carried out in the same manner as in Examples 13 to 20, except that the extract was selected as the test substance.

Table 1 shows the results of Comparative Examples 1 to 4 and Examples 13 to 20.

division Brown stain Example 5 White copy paper invisible White cloth invisible Example 6 White copy paper invisible White cloth invisible Example 7 White copy paper invisible White cloth invisible Example 8 White copy paper invisible White cloth invisible Example 9 White copy paper invisible White cloth invisible Example 10 White copy paper invisible White cloth invisible Example 11 White copy paper invisible White cloth invisible Example 12 White copy paper invisible White cloth invisible Comparative Example 1 White copy paper Obvious White cloth Obvious Comparative Example 2 White copy paper Obvious White cloth Obvious Comparative Example 3 White copy paper Obvious White cloth Obvious Comparative Example 4 White copy paper Obvious White cloth Obvious

As can be seen from the results of Table 1, the cinnamon extract of Comparative Examples 1 to 4, which was not subjected to any distillation process, was sprayed onto white copy paper and white cloth, and when dried, it was confirmed that the brown color appeared clearly. All of the transparent cinnamon extracts after the distillation process were sprayed onto white copy paper and white cloth, and when dried, no brown color was observed.

Experimental example for confirming insect repellent effect

In Example 5 to Example 8 of the present application by using a rotary evaporation concentration apparatus, cinnamon extract, a distillate obtained in a transparent liquid phase, was prepared in the form of an aerosol, respectively, to test the mosquito repelling effect.

After applying the sample provided as a result of Example 5 to Example 8 evenly between the fingers and elbows of healthy adult men who voluntarily participated in the experiment, air-dried for 2 minutes and the arm of the experimenter and the subject's arm that did not apply anything As a comparative example, mosquitoes that absorb blood for 30 minutes at a time of 30 minutes at the same time were netted in a 50 × 50 × 50 cm 3 Bioassay cage containing 100 female red mosquitoes. The numbers were recorded and compared and the results are shown in Table 2 below.

division  Vampire Mosquito  30 minutes  60 minutes  90 minutes  120 minutes  150 minutes  180 minutes  Example 5  0  0  0  One  One  2  Example 6  0  0  0  0  One  3  Example 7  0  0  0  0  0  2  Example 8  0  0  0  0  One  2  Comparative example  11  12  12  11  12  12

As shown in Table 2, the arms of the experimenters coated with the cinnamon extract according to Examples 5 to 8 of the present invention showed an excellent mosquito repellent effect overall, a significant difference from the experimenters did not apply the cinnamon extract Could be confirmed.

Therefore, when the technical idea of the present application is applied, it can be used as an insect repellent by using the active ingredient of cinnamon and also sprayed as a clear cinnamon extract can be obtained when certain distillation conditions are satisfied to prepare a transparent cinnamon extract. After drying, it was confirmed that brown stains did not occur. Accordingly, the purpose of preventing the access of mosquitoes to the human body or to combat the house mites contaminated with indoor space was to prevent clothing, bedding, walls, human body and indoors. The invention was completed by confirming that it is possible to provide an environmentally friendly high-value natural insect repellent of the type that does not occur brown stain even when sprayed on the surface of all the object.

FIG. 1 is a photographic view of a device in which a brown cinnamon extract was applied to an experiment to obtain a transparent cinnamon extract using a rotary evaporator in the application of an embodiment of the present application, which is commonly used in a laboratory. Separate code description is omitted.

Claims (3)

In the insect repellent composition provided as a cinnamon extract,
Cinnamon bark is heated or eluted with water alone or mixed with water and a mixed solvent containing ethanol in the concentration range of 25 to 45 v%, but at a pressure of 2.5 to 2.5 kgf / cm ² and a range of 40 to 125 ° C. Solvent extraction step to which the hot water extraction method is applied
Solid and liquid separation step for separating the solids and the extraction solvent of cinnamon bark present in the solvent during the extraction process;
Transparent cinnamon through the distillation step of the extraction solvent obtained through the solid-liquid separation step is selected from the method of simple batch distillation or fractional distillation under the pressure conditions of the atmospheric pressure ~ decompression state Insect repellent composition, characterized in that provided as an extract. In the manufacturing method of obtaining a transparent insect repellent composition from a cinnamon extract,
The extraction process of heating / eluting cinnamon bark with water alone or with a mixed solvent containing water and ethanol in the concentration range of 25 to 45 v% is performed under normal pressure or 2.5 kgf / cm ² and temperature of 40 ~ 125 ℃. A first step process in which hot water extraction is performed in a range;
A second step of applying a solid-liquid separation process for separating solids and extractant of cinnamon bark present in water during the extraction process by physical filtration;
A third step in which the distillation step of the extraction solvent obtained through the solid-liquid separation step is selected from a simple batch distillation method or a fractional distillation method under a pressure condition at atmospheric pressure or reduced pressure; Method for producing a insect repellent composition comprising the step of obtaining a transparent cinnamon extract. In the method of using the cinnamon extract provided in a transparent liquid,
Extraction process of heating / eluting cinnamon bark with water alone or mixed solvent containing water and ethanol in the range of 25 ~ 45 v% concentration;
Solid and liquid separation process for separating the solids and extracting solvent of cinnamon bark in water after the extraction process and
Method of using a transparent cinnamon extract, characterized in that the transparent cinnamon extract obtained through the distillation process of the extraction solvent obtained through the solid-liquid separation step as a mosquito repellent or an insect repellent insect repellent inhabiting clothes, bedding, wall .

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