KR20130048281A - 확장기 기능장애 또는 확장기 심부전의 예방 또는 치료를 위한 레닌 억제제의 용도 - Google Patents
확장기 기능장애 또는 확장기 심부전의 예방 또는 치료를 위한 레닌 억제제의 용도 Download PDFInfo
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- KR20130048281A KR20130048281A KR1020137010963A KR20137010963A KR20130048281A KR 20130048281 A KR20130048281 A KR 20130048281A KR 1020137010963 A KR1020137010963 A KR 1020137010963A KR 20137010963 A KR20137010963 A KR 20137010963A KR 20130048281 A KR20130048281 A KR 20130048281A
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61720204P | 2004-10-08 | 2004-10-08 | |
| US60/617,202 | 2004-10-08 | ||
| US66789905P | 2005-04-01 | 2005-04-01 | |
| US60/667,899 | 2005-04-01 | ||
| PCT/US2005/035914 WO2006041974A1 (en) | 2004-10-08 | 2005-10-06 | Use of renin inhibitors for the prevention or treatment of diastolic dysfunction or diastolic heart failure |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077007885A Division KR20070101843A (ko) | 2004-10-08 | 2005-10-06 | 확장기 기능장애 또는 확장기 심부전의 예방 또는 치료를위한 레닌 억제제의 용도 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20130048281A true KR20130048281A (ko) | 2013-05-09 |
Family
ID=35789048
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077007885A Ceased KR20070101843A (ko) | 2004-10-08 | 2005-10-06 | 확장기 기능장애 또는 확장기 심부전의 예방 또는 치료를위한 레닌 억제제의 용도 |
| KR1020137010963A Withdrawn KR20130048281A (ko) | 2004-10-08 | 2005-10-06 | 확장기 기능장애 또는 확장기 심부전의 예방 또는 치료를 위한 레닌 억제제의 용도 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077007885A Ceased KR20070101843A (ko) | 2004-10-08 | 2005-10-06 | 확장기 기능장애 또는 확장기 심부전의 예방 또는 치료를위한 레닌 억제제의 용도 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20080085914A1 (enExample) |
| EP (2) | EP1799199B1 (enExample) |
| JP (1) | JP2008515903A (enExample) |
| KR (2) | KR20070101843A (enExample) |
| CN (1) | CN101102755B (enExample) |
| AT (1) | ATE551052T1 (enExample) |
| AU (2) | AU2005294318A1 (enExample) |
| BR (1) | BRPI0516128A (enExample) |
| CA (1) | CA2580862A1 (enExample) |
| ES (1) | ES2384637T3 (enExample) |
| MX (1) | MX2007004020A (enExample) |
| PL (1) | PL1799199T3 (enExample) |
| PT (1) | PT1799199E (enExample) |
| RU (1) | RU2407523C2 (enExample) |
| WO (1) | WO2006041974A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1972335A1 (en) * | 2007-03-23 | 2008-09-24 | Krka | Solid dosage forms comprising aliskiren and pharmaceutically acceptable salts thereof |
| MX2009010427A (es) | 2007-03-27 | 2009-10-20 | Calpis Co Ltd | Agente profilactico para la insuficiencia cardiaca. |
| ATE505203T1 (de) * | 2007-09-28 | 2011-04-15 | Novartis Ag | Pharmazeutische kombination aus aliskiren und valsartan |
| AU2008309058B2 (en) * | 2007-09-28 | 2012-08-09 | Novartis Ag | Galenical formulations of Aliskiren and Valsartan |
| MX2011007779A (es) * | 2009-01-28 | 2011-08-12 | Novartis Ag | Formulaciones galenicas de compuestos organicos. |
| EP2216020A1 (en) * | 2009-02-05 | 2010-08-11 | KRKA, tovarna zdravil, d.d., Novo mesto | Moisture-activated granulation process |
| EP2340820A1 (en) * | 2009-12-16 | 2011-07-06 | KRKA, tovarna zdravil, d.d., Novo mesto | Moisture-activated granulation process |
| EP2393489B1 (en) * | 2009-02-05 | 2014-10-08 | Krka, tovarna zdravil, d.d., Novo mesto | Moisture-activated granulation process |
| US20120107397A1 (en) * | 2009-07-03 | 2012-05-03 | Hetero Research Foundation | Pharmaceutical compositions of valsartan |
| US20110268797A1 (en) * | 2010-04-30 | 2011-11-03 | Sanovel IIac Sanayi Ve Ticaret Anonim Sirketi | Multicoated aliskiren formulations |
| FR2961105B1 (fr) * | 2010-06-15 | 2013-02-08 | Servier Lab | Utilisation de l'association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion de l'angiotensine pour le traitement de l'insuffisance cardiaque |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1334092C (en) | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
| ATE190051T1 (de) | 1989-06-14 | 2000-03-15 | Smithkline Beecham Corp | Imidazoalkensäure |
| DE122010000024I1 (de) | 1990-02-19 | 2010-07-08 | Novartis Ag | Acylverbindungen |
| PT97078B (pt) | 1990-03-20 | 1997-07-31 | Sanofi Sa | Processo para a preparacao de derivados heterociclicos n-substituidos e de composicoes farmaceuticas que os contem |
| US5196444A (en) | 1990-04-27 | 1993-03-23 | Takeda Chemical Industries, Ltd. | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof |
| KR970005839B1 (ko) * | 1990-05-11 | 1997-04-21 | 화이자 인코포레이티드 | 상승 치료효과를 얻기 위한 조성물 및 방법 |
| IE920540A1 (en) | 1991-02-21 | 1992-08-26 | Sankyo Co | 1-biphenylmethylimidazole derivatives, their preparation and¹their therapetuic use |
| DE4121975A1 (de) | 1991-07-03 | 1993-01-07 | Basf Ag | Thermoplastische formmassen auf der basis von polycarbonaten, styrol/acrylnitril-polymerisaten und polyolefinen |
| TW226375B (enExample) | 1991-10-24 | 1994-07-11 | American Home Prod | |
| MY119161A (en) | 1994-04-18 | 2005-04-30 | Novartis Ag | Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities |
| US6376672B1 (en) | 1999-04-27 | 2002-04-23 | Hoffmann-La Roche Inc. | Naphthalenylmethoxypiperidines as renin inhibitors |
| US6197959B1 (en) | 1999-04-27 | 2001-03-06 | Hoffmann-La Roche Inc. | Piperidine derivatives |
| US8168616B1 (en) * | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
| CA2430924A1 (en) * | 2000-12-01 | 2002-06-06 | Novartis Ag | Angiotensin receptor antagonist composition for the treatment of sexual dysfunction associated with hypertension and another condition |
| US7019010B2 (en) * | 2001-09-27 | 2006-03-28 | Novertis Ag | Combinations |
| GB0212410D0 (en) * | 2002-05-29 | 2002-07-10 | Novartis Ag | Organic compounds |
| GB0212412D0 (en) * | 2002-05-29 | 2002-07-10 | Novartis Ag | Combination of organic compounds |
| JP2005537822A (ja) * | 2002-06-28 | 2005-12-15 | ノバルティス アクチエンゲゼルシャフト | 有機化合物の使用 |
| CN1882528A (zh) * | 2003-11-26 | 2006-12-20 | 诺瓦提斯公司 | 有机化合物 |
| CA2546264A1 (en) * | 2003-11-26 | 2005-06-09 | Novartis Ag | 4-phenylpiperidine derivatives as renin inhibitors |
| GB0327839D0 (en) * | 2003-12-01 | 2003-12-31 | Novartis Ag | Organic compounds |
| PE20050596A1 (es) * | 2003-12-19 | 2005-10-18 | Novartis Ag | Microemulsion que comprende un inhibidor renina |
| MY146830A (en) * | 2005-02-11 | 2012-09-28 | Novartis Ag | Combination of organic compounds |
-
2005
- 2005-10-06 WO PCT/US2005/035914 patent/WO2006041974A1/en not_active Ceased
- 2005-10-06 RU RU2007116863/15A patent/RU2407523C2/ru not_active IP Right Cessation
- 2005-10-06 CN CN2005800340394A patent/CN101102755B/zh not_active Expired - Fee Related
- 2005-10-06 US US11/576,495 patent/US20080085914A1/en not_active Abandoned
- 2005-10-06 BR BRPI0516128-2A patent/BRPI0516128A/pt not_active IP Right Cessation
- 2005-10-06 PL PL05810560T patent/PL1799199T3/pl unknown
- 2005-10-06 EP EP05810560A patent/EP1799199B1/en not_active Revoked
- 2005-10-06 AT AT05810560T patent/ATE551052T1/de active
- 2005-10-06 ES ES05810560T patent/ES2384637T3/es not_active Expired - Lifetime
- 2005-10-06 EP EP10008427A patent/EP2248520A3/en not_active Withdrawn
- 2005-10-06 KR KR1020077007885A patent/KR20070101843A/ko not_active Ceased
- 2005-10-06 PT PT05810560T patent/PT1799199E/pt unknown
- 2005-10-06 MX MX2007004020A patent/MX2007004020A/es active IP Right Grant
- 2005-10-06 JP JP2007535795A patent/JP2008515903A/ja not_active Ceased
- 2005-10-06 KR KR1020137010963A patent/KR20130048281A/ko not_active Withdrawn
- 2005-10-06 CA CA002580862A patent/CA2580862A1/en not_active Abandoned
- 2005-10-06 AU AU2005294318A patent/AU2005294318A1/en not_active Abandoned
-
2010
- 2010-03-04 AU AU2010200833A patent/AU2010200833B2/en not_active Ceased
-
2012
- 2012-12-10 US US13/709,549 patent/US20130196977A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20130196977A1 (en) | 2013-08-01 |
| PL1799199T3 (pl) | 2012-09-28 |
| CN101102755A (zh) | 2008-01-09 |
| AU2010200833A1 (en) | 2010-04-01 |
| PT1799199E (pt) | 2012-07-03 |
| US20080085914A1 (en) | 2008-04-10 |
| RU2007116863A (ru) | 2008-11-20 |
| MX2007004020A (es) | 2007-05-24 |
| EP2248520A2 (en) | 2010-11-10 |
| BRPI0516128A (pt) | 2008-08-26 |
| ES2384637T3 (es) | 2012-07-10 |
| EP2248520A3 (en) | 2010-11-17 |
| JP2008515903A (ja) | 2008-05-15 |
| EP1799199B1 (en) | 2012-03-28 |
| CN101102755B (zh) | 2013-01-02 |
| ATE551052T1 (de) | 2012-04-15 |
| CA2580862A1 (en) | 2006-04-20 |
| AU2010200833B2 (en) | 2011-07-14 |
| EP1799199A1 (en) | 2007-06-27 |
| KR20070101843A (ko) | 2007-10-17 |
| AU2005294318A1 (en) | 2006-04-20 |
| WO2006041974A1 (en) | 2006-04-20 |
| RU2407523C2 (ru) | 2010-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A107 | Divisional application of patent | ||
| PA0104 | Divisional application for international application |
Comment text: Divisional Application for International Patent Patent event code: PA01041R01D Patent event date: 20130429 |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |