KR20120106788A - 프로스트글란딘 효능제 약물의 안정한 수성 조성물 및 그의 사용방법 - Google Patents

프로스트글란딘 효능제 약물의 안정한 수성 조성물 및 그의 사용방법 Download PDF

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Publication number
KR20120106788A
KR20120106788A KR1020127017676A KR20127017676A KR20120106788A KR 20120106788 A KR20120106788 A KR 20120106788A KR 1020127017676 A KR1020127017676 A KR 1020127017676A KR 20127017676 A KR20127017676 A KR 20127017676A KR 20120106788 A KR20120106788 A KR 20120106788A
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South Korea
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composition
carboxylic acid
alkyl
disease
prostanoid
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Ceased
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KR1020127017676A
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English (en)
Korean (ko)
Inventor
로버트 엠. 버크
화 빈 아이엠
Original Assignee
알러간, 인코포레이티드
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43503864&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20120106788(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 알러간, 인코포레이티드 filed Critical 알러간, 인코포레이티드
Publication of KR20120106788A publication Critical patent/KR20120106788A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/559Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing hetero atoms other than oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020127017676A 2009-12-09 2010-11-05 프로스트글란딘 효능제 약물의 안정한 수성 조성물 및 그의 사용방법 Ceased KR20120106788A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26789709P 2009-12-09 2009-12-09
US61/267,897 2009-12-09

Publications (1)

Publication Number Publication Date
KR20120106788A true KR20120106788A (ko) 2012-09-26

Family

ID=43503864

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127017676A Ceased KR20120106788A (ko) 2009-12-09 2010-11-05 프로스트글란딘 효능제 약물의 안정한 수성 조성물 및 그의 사용방법

Country Status (16)

Country Link
US (2) US20110136872A1 (cg-RX-API-DMAC7.html)
EP (1) EP2509582A1 (cg-RX-API-DMAC7.html)
JP (2) JP5955774B2 (cg-RX-API-DMAC7.html)
KR (1) KR20120106788A (cg-RX-API-DMAC7.html)
CN (1) CN102762195B (cg-RX-API-DMAC7.html)
AR (1) AR078929A1 (cg-RX-API-DMAC7.html)
AU (1) AU2010328555B2 (cg-RX-API-DMAC7.html)
CA (1) CA2783707A1 (cg-RX-API-DMAC7.html)
CL (1) CL2012001545A1 (cg-RX-API-DMAC7.html)
IL (1) IL220240A0 (cg-RX-API-DMAC7.html)
MX (1) MX2012006622A (cg-RX-API-DMAC7.html)
NZ (1) NZ600577A (cg-RX-API-DMAC7.html)
RU (1) RU2012127869A (cg-RX-API-DMAC7.html)
SG (1) SG181600A1 (cg-RX-API-DMAC7.html)
TW (1) TW201138766A (cg-RX-API-DMAC7.html)
WO (1) WO2011071620A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012113019A1 (de) 2012-09-25 2014-03-27 Lg Display Co., Ltd. Anzeigevorrichtung und Verfahren zum Detektieren von Leitungsdefekten der Anzeigevorrichtung

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102304111B1 (ko) 2012-08-27 2021-09-23 알레간 인코포레이티드 베타-클로로시클로펜탄의 친수성 에스테르 전구약물의 이용에 의한 감소된 중심 각막 비후
TR201902864T4 (tr) * 2014-02-20 2019-03-21 Allergan Inc Beta-klorosiklopentanların hidrofilik ester ön ilaçlarının kullanımı ile azaltılmış merkezi korneal kalınlaşma.
EP3201192B1 (en) 2014-10-02 2019-08-21 Allergan, Inc. Ester prodrugs of gamma-lactams and their use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5028624A (en) * 1989-07-27 1991-07-02 Allergan, Inc. Intraocular pressure reducing 9,15-diacyl prostaglandins
CA2021316C (en) * 1989-07-27 2000-10-24 Ming Fai Chan Intraocular pressure reducing 11-acyl prostaglandins
US4994274A (en) * 1989-07-27 1991-02-19 Allergan, Inc. Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using
US5034413A (en) 1989-07-27 1991-07-23 Allergan, Inc. Intraocular pressure reducing 9,11-diacyl prostaglandins
EP1109546A1 (en) * 1998-07-21 2001-06-27 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
EP1321144B1 (en) * 2000-09-13 2010-12-08 Santen Pharmaceutical Co., Ltd. Eye drops
KR20100132557A (ko) * 2002-08-23 2010-12-17 산텐 세이야꾸 가부시키가이샤 라타노프로스트를 유효 성분으로 하는 점안액의 안정화 방법
DE602004018990D1 (de) * 2004-05-26 2009-02-26 Bayardo Arturo Jimenez Verfahren zur herstellung einer latanoprost-augenlösung und so hergestellte lösung
US20050276867A1 (en) * 2004-06-09 2005-12-15 Allergan, Inc. Stabilized compositions comprising a therapeutically active agent and an oxidizing preservative
MX2007010818A (es) * 2005-03-10 2007-11-12 Allergan Inc Gamma lactamas sustituidas como agentes terapeuticos.
JPWO2008096804A1 (ja) * 2007-02-07 2010-05-27 テイカ製薬株式会社 ラタノプロスト含有点眼剤
MX2010011636A (es) * 2008-04-24 2010-11-25 Allergan Inc Gamma lactamas sustituidas como agentes terapeuticos.
EP2127638A1 (en) * 2008-05-30 2009-12-02 Santen Pharmaceutical Co., Ltd Method and composition for treating ocular hypertension and glaucoma

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012113019A1 (de) 2012-09-25 2014-03-27 Lg Display Co., Ltd. Anzeigevorrichtung und Verfahren zum Detektieren von Leitungsdefekten der Anzeigevorrichtung

Also Published As

Publication number Publication date
JP2016056207A (ja) 2016-04-21
MX2012006622A (es) 2012-08-15
CL2012001545A1 (es) 2012-08-31
CN102762195A (zh) 2012-10-31
JP5955774B2 (ja) 2016-07-20
IL220240A0 (en) 2012-07-31
NZ600577A (en) 2014-10-31
CN102762195B (zh) 2016-05-18
EP2509582A1 (en) 2012-10-17
AR078929A1 (es) 2011-12-14
AU2010328555A1 (en) 2012-07-05
US20110136872A1 (en) 2011-06-09
US20160220677A1 (en) 2016-08-04
AU2010328555B2 (en) 2016-05-26
WO2011071620A1 (en) 2011-06-16
TW201138766A (en) 2011-11-16
JP2013513606A (ja) 2013-04-22
CA2783707A1 (en) 2011-06-16
SG181600A1 (en) 2012-07-30
RU2012127869A (ru) 2014-01-20

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