KR20120104177A - 암을 치료하기 위한 톨 유사 수용체 및 효능제의 용도 - Google Patents

암을 치료하기 위한 톨 유사 수용체 및 효능제의 용도 Download PDF

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KR20120104177A
KR20120104177A KR1020127008759A KR20127008759A KR20120104177A KR 20120104177 A KR20120104177 A KR 20120104177A KR 1020127008759 A KR1020127008759 A KR 1020127008759A KR 20127008759 A KR20127008759 A KR 20127008759A KR 20120104177 A KR20120104177 A KR 20120104177A
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hours
vector
mammal
flagellin
toll
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Korean (ko)
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안드레이 브이. 구드코프
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파나셀라 랩스, 아이엔씨.
로스웰 파크 캔서 인스티튜트
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    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K38/18—Growth factors; Growth regulators
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    • A61K38/22—Hormones
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    • A61P31/12—Antivirals
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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KR1020127008759A 2009-10-06 2010-10-06 암을 치료하기 위한 톨 유사 수용체 및 효능제의 용도 Ceased KR20120104177A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24925309P 2009-10-06 2009-10-06
US61/249,253 2009-10-06
US24959609P 2009-10-07 2009-10-07
US61/249,596 2009-10-07

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KR20120104177A true KR20120104177A (ko) 2012-09-20

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KR1020127008759A Ceased KR20120104177A (ko) 2009-10-06 2010-10-06 암을 치료하기 위한 톨 유사 수용체 및 효능제의 용도

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US (1) US9205095B2 (OSRAM)
EP (1) EP2486134B1 (OSRAM)
JP (2) JP5796014B2 (OSRAM)
KR (1) KR20120104177A (OSRAM)
CN (1) CN104136614B (OSRAM)
AP (1) AP2012006253A0 (OSRAM)
AU (1) AU2010303464B2 (OSRAM)
BR (1) BR112012011331B8 (OSRAM)
CA (1) CA2777198C (OSRAM)
EA (1) EA021842B1 (OSRAM)
ES (1) ES2457518T3 (OSRAM)
IL (1) IL219060A (OSRAM)
MX (1) MX2012004095A (OSRAM)
MY (1) MY163110A (OSRAM)
WO (1) WO2011044246A1 (OSRAM)
ZA (1) ZA201202500B (OSRAM)

Cited By (3)

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KR101634380B1 (ko) 2015-06-23 2016-06-28 한국생산기술연구원 Tlr5 아고니스트 단백질의 생산방법
KR20210098544A (ko) * 2016-12-28 2021-08-10 에이에스엠엘 네델란즈 비.브이. 메트롤로지 이미지와 디자인 사이의 시뮬레이션-지원 정렬
WO2021246666A1 (ko) * 2020-06-04 2021-12-09 가톨릭대학교 산학협력단 플라젤린으로부터 유도된 tlr5 작용제를 유효성분으로 포함하는 항암제 조성물

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EP1838340B1 (en) 2004-12-22 2018-04-04 Cleveland Clinic Foundation Flagellin related polypeptides and uses thereof
CN102170911B (zh) 2008-08-01 2014-07-02 克里夫兰生物实验室公司 用于治疗再灌注损伤的方法
KR20140030132A (ko) 2011-01-10 2014-03-11 클리브랜드 바이오랩스, 아이엔씨. 암을 치료하기 위한 톨-유사 수용체 효능제의 용도
WO2014098649A1 (en) * 2012-12-18 2014-06-26 Obschestvo S Ogranichennoy Otvetstvennostyu "Panacela Labs" Compositions and methods using toll-like receptor 5 and toll-like receptor agonist
WO2015080631A1 (en) * 2013-11-27 2015-06-04 Obschestvo S Ogranichennoy Otvetstvennost`Yu "Panacela Labs" Improved expression vector for toll-like receptor and agonist and use for treating cancer
US10202426B2 (en) 2014-07-30 2019-02-12 Genome Protection, Inc. Flagellin compositions and uses
US10537626B2 (en) 2014-10-07 2020-01-21 Cytlimic Inc. HSP70-derived peptide, pharmaceutical composition for treating or preventing cancer using same, immunity inducer, and method for producing antigen presenting cell
US10183056B2 (en) 2014-10-16 2019-01-22 Cleveland Biolabs, Inc. Methods and compositions for the treatment of radiation-related disorders
JP6898225B2 (ja) 2015-03-09 2021-07-07 サイトリミック株式会社 Ｇｐｃ３由来のペプチド、これを用いた癌の治療又は予防のための医薬組成物、免疫誘導剤、及び抗原提示細胞の製造方法
EP3797794A1 (en) 2015-04-07 2021-03-31 Cytlimic Inc. Medicine comprising a toll like receptor 3 agonist and a lag-3 protein
CN105801709B (zh) * 2016-04-29 2019-10-08 北京纽莱福生物科技有限公司 CBLB502-Fc融合蛋白及其制备方法
AU2017342189B2 (en) 2016-10-11 2023-09-21 Nec Corporation Medicine
WO2018088933A1 (en) * 2016-11-14 2018-05-17 Limited Liability Company "Panacela Labs" Anti-tumor effects of a viral vector encoding a toll-like receptor and a toll-like receptor agonist
WO2018210279A1 (zh) * 2017-05-16 2018-11-22 科济生物医药（上海）有限公司 Toll样受体激动剂与免疫效应细胞的联用
UY37816A (es) 2017-07-20 2019-02-28 Spogen Biotech Inc Polipéptidos bioactivos para mejorar la protección, crecimiento y productividad en plantas
EP3768285A1 (en) 2018-03-19 2021-01-27 4D Pharma Research Limited Compositions comprising bacterial strains
US12440536B2 (en) 2018-05-18 2025-10-14 The University Of Hong Kong Compositions of toll-like receptor 5 (TLR5) agonist and methods of use thereof
WO2020041720A1 (en) 2018-08-24 2020-02-27 Codiak Biosciences, Inc. Extracellular vesicles targeting dendritic cells and uses thereof
EP3921432A1 (en) 2019-02-04 2021-12-15 Codiak BioSciences, Inc. Membrane protein scaffolds for exosome engineering
US12233356B2 (en) 2019-03-21 2025-02-25 Lonza Sales Ag Process for preparing extracellular vesicles
CA3133314A1 (en) 2019-03-21 2020-09-24 Codiak Biosciences, Inc. Extracellular vesicle conjugates and uses thereof
US12502427B2 (en) 2019-03-21 2025-12-23 Lonza Sales Ag Extracellular vesicles for vaccine delivery
US20220251200A1 (en) 2019-07-03 2022-08-11 Codiak Biosciences, Inc. Extracellular vesicles targeting t cells and uses thereof
JP2022549328A (ja) 2019-09-25 2022-11-24 コディアック バイオサイエンシーズ， インコーポレイテッド 細胞外小胞組成物
US20230114434A1 (en) 2020-03-13 2023-04-13 Codiak Biosciences, Inc. Extracellular vesicles for treating neurological disorders
JP2023518414A (ja) 2020-03-20 2023-05-01 コディアック バイオサイエンシーズ， インコーポレイテッド 治療のための細胞外小胞
WO2021237100A1 (en) 2020-05-21 2021-11-25 Codiak Biosciences, Inc. Methods of targeting extracellular vesicles to lung
WO2021248133A1 (en) 2020-06-05 2021-12-09 Codiak Biosciences, Inc. Anti-transferrin extracellular vesicles
US20240241020A1 (en) 2020-09-23 2024-07-18 Lonza Sales Ag Process for preparing extracellular vesicles
US20240082389A1 (en) 2020-09-23 2024-03-14 Lonza Sales Ag Methods of producing extracellular vesicles
WO2022066883A1 (en) 2020-09-23 2022-03-31 Codiak Biosciences, Inc. Extracellular vesicles comprising kras antigens and uses thereof
WO2025196053A1 (en) * 2024-03-18 2025-09-25 Istituto Europeo Di Oncologia S.R.L. Flagellin-related peptides and uses thereof
EP4620482A1 (en) * 2024-03-18 2025-09-24 Istituto Europeo di Oncologia S.r.l. Flagellin-related peptides and uses thereof

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US8703146B2 (en) * 2001-04-20 2014-04-22 Institute For Systems Biology Toll-like receptor 5 ligands and methods of use
EP1838340B1 (en) * 2004-12-22 2018-04-04 Cleveland Clinic Foundation Flagellin related polypeptides and uses thereof
CA2594612A1 (en) * 2005-01-19 2006-07-27 Vaxinnate Corporation Compositions comprising pathogen-associated molecular patterns and antigens and their use to stimulate an immune response
WO2009102818A1 (en) * 2008-02-11 2009-08-20 Cleveland Biolabs, Inc. Method for reducing the effects of chemotheraphy using flagellin related polypeptides

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101634380B1 (ko) 2015-06-23 2016-06-28 한국생산기술연구원 Tlr5 아고니스트 단백질의 생산방법
US10711049B2 (en) 2015-06-23 2020-07-14 Korea Institute Of Industrial Technology Method for producing TLR5 agonist protein
KR20210098544A (ko) * 2016-12-28 2021-08-10 에이에스엠엘 네델란즈 비.브이. 메트롤로지 이미지와 디자인 사이의 시뮬레이션-지원 정렬
WO2021246666A1 (ko) * 2020-06-04 2021-12-09 가톨릭대학교 산학협력단 플라젤린으로부터 유도된 tlr5 작용제를 유효성분으로 포함하는 항암제 조성물

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IL219060A (en) 2017-02-28
BR112012011331B1 (pt) 2021-03-02
CA2777198A1 (en) 2011-04-14
ES2457518T3 (es) 2014-04-28
WO2011044246A1 (en) 2011-04-14
EP2486134A4 (en) 2013-02-13
EP2486134A1 (en) 2012-08-15
BR112012011331A2 (pt) 2015-09-15
AU2010303464A1 (en) 2012-04-12
CN104136614B (zh) 2018-04-06
AP2012006253A0 (en) 2012-06-30
CA2777198C (en) 2018-07-24
EA021842B1 (ru) 2015-09-30
US9205095B2 (en) 2015-12-08
JP2013506437A (ja) 2013-02-28
CN104136614A (zh) 2014-11-05
BR112012011331B8 (pt) 2021-05-25
EP2486134B1 (en) 2014-01-08
ZA201202500B (en) 2013-06-26
MX2012004095A (es) 2012-09-12
JP2015165821A (ja) 2015-09-24
EA201290140A1 (ru) 2012-11-30
MY163110A (en) 2017-08-15
HK1199058A1 (en) 2015-06-19
IL219060A0 (en) 2012-06-28
US20120208871A1 (en) 2012-08-16
JP5796014B2 (ja) 2015-10-21
AU2010303464B2 (en) 2014-05-01

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