KR20120103557A - 파킨슨씨병 치료용 조성물 및 치료방법 - Google Patents

파킨슨씨병 치료용 조성물 및 치료방법 Download PDF

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Publication number
KR20120103557A
KR20120103557A KR1020127005095A KR20127005095A KR20120103557A KR 20120103557 A KR20120103557 A KR 20120103557A KR 1020127005095 A KR1020127005095 A KR 1020127005095A KR 20127005095 A KR20127005095 A KR 20127005095A KR 20120103557 A KR20120103557 A KR 20120103557A
Authority
KR
South Korea
Prior art keywords
dopamine
receptor
days
disease
parkinson
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020127005095A
Other languages
English (en)
Korean (ko)
Inventor
필립 시맨
Original Assignee
클레라 아이엔씨.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 클레라 아이엔씨. filed Critical 클레라 아이엔씨.
Publication of KR20120103557A publication Critical patent/KR20120103557A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4515—Non condensed piperidines, e.g. piperocaine having a butyrophenone group in position 1, e.g. haloperidol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020127005095A 2009-07-31 2010-07-30 파킨슨씨병 치료용 조성물 및 치료방법 Ceased KR20120103557A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23026409P 2009-07-31 2009-07-31
US61/230,264 2009-07-31

Publications (1)

Publication Number Publication Date
KR20120103557A true KR20120103557A (ko) 2012-09-19

Family

ID=43528672

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127005095A Ceased KR20120103557A (ko) 2009-07-31 2010-07-30 파킨슨씨병 치료용 조성물 및 치료방법

Country Status (12)

Country Link
US (1) US9192605B2 (https=)
EP (1) EP2459194A4 (https=)
JP (1) JP5756105B2 (https=)
KR (1) KR20120103557A (https=)
CN (1) CN102548555A (https=)
AU (1) AU2010278645A1 (https=)
BR (1) BR112012008193A2 (https=)
CA (1) CA2769149A1 (https=)
IL (1) IL217149A0 (https=)
MX (1) MX2012001290A (https=)
NZ (1) NZ598247A (https=)
WO (1) WO2011011886A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3178035A1 (en) * 2012-12-24 2014-07-03 Neurogastrx, Inc. Methods for treating gi tract disorders
JP6371716B2 (ja) * 2014-04-01 2018-08-08 東京エレクトロン株式会社 基板液処理装置及び基板液処理方法並びに基板液処理プログラムを記録したコンピュータ読み取り可能な記録媒体
US9844554B2 (en) 2014-06-24 2017-12-19 Neurogastrx, Inc. Prodrugs of metopimazine
US10836757B1 (en) 2020-04-02 2020-11-17 Neurogastrx, Inc. Polymorphic forms of metopimazine
CN114601928B (zh) * 2022-04-02 2023-03-17 首都医科大学 一种钙超载介导神经元死亡的标志物及应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1219667B (it) 1988-06-21 1990-05-24 Polifarma Spa Impiego di uridina nel trattamento farmacologico di disturbi dovuti ad alterato equilibrio dopaminergico
RU2057529C1 (ru) * 1994-05-30 1996-04-10 Алексей Михайлович Коршунов Способ лечения синдрома паркинсонизма
US20010056101A1 (en) * 1998-06-29 2001-12-27 Carol A. Tamminga Use of dopamine receptor antagonists in combination with partial dopamine agonist to prevent tolerance in treating nervous disorders related to dopamine dysfunction
DE10111486A1 (de) * 2001-03-09 2002-10-02 Ralph R Dawirs Verwendung einer oder mehrerer neuroaktiver Substanzen zur Behandlung der Parkinsonschen Krankheit
ES2286453T3 (es) 2002-09-17 2007-12-01 Motac Neuroscience Limited Tratamiento de la discinesia.
JP2006505589A (ja) 2002-10-22 2006-02-16 ドラッグアビューズ サイエンシズ エス．アー．エス． 選択的ドーパミンｄ１受容体アゴニストを使用した認知障害の治療法
EP1812081A1 (en) * 2004-11-03 2007-08-01 Clera Inc. Method to detect dopamine receptors in the functional d2high state
NZ586963A (en) * 2008-02-05 2012-11-30 Clera Inc Use of dopamine d2 receptor inhibitors for alleviating depression or improving cognition

Also Published As

Publication number Publication date
EP2459194A4 (en) 2012-12-19
US9192605B2 (en) 2015-11-24
EP2459194A1 (en) 2012-06-06
IL217149A0 (en) 2012-02-29
CA2769149A1 (en) 2011-02-03
AU2010278645A1 (en) 2012-03-08
JP5756105B2 (ja) 2015-07-29
MX2012001290A (es) 2012-06-12
JP2013500943A (ja) 2013-01-10
NZ598247A (en) 2014-01-31
BR112012008193A2 (pt) 2016-03-01
WO2011011886A1 (en) 2011-02-03
US20120115910A1 (en) 2012-05-10
CN102548555A (zh) 2012-07-04

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Patent event date: 20120227

Patent event code: PA01051R01D

Comment text: International Patent Application

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Patent event code: PA02012R01D

Patent event date: 20150728

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Patent event code: PE06011S01I