KR20110013450A - 간엽 줄기 세포 및 골-형성 세포 - Google Patents
간엽 줄기 세포 및 골-형성 세포 Download PDFInfo
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- KR20110013450A KR20110013450A KR20107027373A KR20107027373A KR20110013450A KR 20110013450 A KR20110013450 A KR 20110013450A KR 20107027373 A KR20107027373 A KR 20107027373A KR 20107027373 A KR20107027373 A KR 20107027373A KR 20110013450 A KR20110013450 A KR 20110013450A
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- cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/12—Phosphorus-containing materials, e.g. apatite
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
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- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
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- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0664—Dental pulp stem cells, Dental follicle stem cells
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- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
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- C12N5/0662—Stem cells
- C12N5/0666—Mesenchymal stem cells from hair follicles
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- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
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- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs
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- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
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- Engineering & Computer Science (AREA)
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- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Botany (AREA)
- Ceramic Engineering (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08155764 | 2008-05-07 | ||
| EP08155764.7 | 2008-05-07 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167013649A Division KR20160065213A (ko) | 2008-05-07 | 2009-05-07 | 간엽 줄기 세포 및 골-형성 세포 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20110013450A true KR20110013450A (ko) | 2011-02-09 |
Family
ID=39769308
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20107027373A Ceased KR20110013450A (ko) | 2008-05-07 | 2009-05-07 | 간엽 줄기 세포 및 골-형성 세포 |
| KR1020167013649A Ceased KR20160065213A (ko) | 2008-05-07 | 2009-05-07 | 간엽 줄기 세포 및 골-형성 세포 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167013649A Ceased KR20160065213A (ko) | 2008-05-07 | 2009-05-07 | 간엽 줄기 세포 및 골-형성 세포 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9371515B2 (enExample) |
| EP (1) | EP2291516B1 (enExample) |
| JP (2) | JP6097479B2 (enExample) |
| KR (2) | KR20110013450A (enExample) |
| CN (1) | CN102016008A (enExample) |
| AU (1) | AU2009245751B2 (enExample) |
| BE (1) | BE1018748A3 (enExample) |
| CA (1) | CA2722625A1 (enExample) |
| WO (1) | WO2009135905A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110013450A (ko) * | 2008-05-07 | 2011-02-09 | 본 테라퓨틱스 소시에테아노님 | 간엽 줄기 세포 및 골-형성 세포 |
| US9192695B2 (en) | 2008-11-20 | 2015-11-24 | Allosource | Allografts combined with tissue derived stem cells for bone healing |
| WO2011155649A1 (en) * | 2010-06-11 | 2011-12-15 | University-Industry Cooperation Group Of Kyunghee University | Agent for osteogenesis using substance-p and preparation process thereof |
| KR102108245B1 (ko) * | 2011-11-30 | 2020-05-08 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 중간엽 간질 세포 및 이에 관련된 용도 |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| CN102827807B (zh) * | 2012-09-19 | 2014-04-16 | 北京京蒙高科干细胞技术有限公司 | 一种间充质干细胞无血清培养基 |
| WO2014113704A2 (en) * | 2013-01-18 | 2014-07-24 | Escape Therapeutics, Inc. | Enhanced differentiation of mesenchymal stem cells |
| KR102312720B1 (ko) | 2013-03-15 | 2021-10-13 | 알로소스 | 연조직 회복 및 재생을 위한 세포 재배치된 콜라겐 매트릭스 |
| KR101528305B1 (ko) * | 2013-06-25 | 2015-06-11 | 사회복지법인 삼성생명공익재단 | 중간엽 줄기세포로부터 유래된, 내피세포의 특성을 포함하는 신규한 줄기세포 |
| DK3083944T3 (da) * | 2013-12-19 | 2021-02-15 | Univ Liege | Pattedyrsmuskelafledte stamceller |
| WO2015155777A1 (en) * | 2014-04-10 | 2015-10-15 | Bonus Therapeutics Ltd. | Bone repair compositions |
| CA3017772C (en) | 2016-03-16 | 2023-02-21 | Cynata Therapeutics Limited | Colony forming medium and use thereof |
| WO2019006328A1 (en) | 2017-06-30 | 2019-01-03 | Allosource | CELL BONE GRAFTS, AND METHODS OF MAKING AND USING |
| KR20210076018A (ko) * | 2018-09-25 | 2021-06-23 | 본 테라퓨틱스 소시에테아노님 | 체외 분화 세포의 골형성능을 판정하기 위한 방법 및 용도 |
| KR20240089678A (ko) * | 2021-11-18 | 2024-06-20 | 고쿠리츠 다이가쿠호우징 도쿄이카시카다이가쿠 | 간엽계 줄기세포를 포함하는 세포 집단, 세포 시트 및 세포 시트의 제조 방법 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US5837539A (en) | 1990-11-16 | 1998-11-17 | Osiris Therapeutics, Inc. | Monoclonal antibodies for human mesenchymal stem cells |
| US5811094A (en) | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
| CN1104257C (zh) | 1993-03-29 | 2003-04-02 | 津莫吉尼蒂克斯公司 | 含pdgf和维生素d的刺激成骨细胞生长的组合物 |
| US5972703A (en) | 1994-08-12 | 1999-10-26 | The Regents Of The University Of Michigan | Bone precursor cells: compositions and methods |
| US5736396A (en) | 1995-01-24 | 1998-04-07 | Case Western Reserve University | Lineage-directed induction of human mesenchymal stem cell differentiation |
| US5827740A (en) | 1996-07-30 | 1998-10-27 | Osiris Therapeutics, Inc. | Adipogenic differentiation of human mesenchymal stem cells |
| WO2000007639A1 (en) | 1998-08-07 | 2000-02-17 | Tissue Engineering, Inc. | Bone precursor compositions |
| EP1099754A1 (en) * | 1999-11-10 | 2001-05-16 | Universiteit Leiden | Mesenchymal stem cells and/or progenitor cells, their isolation and use |
| US20030032034A1 (en) * | 2001-03-05 | 2003-02-13 | Tang Y. Tom | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| DE10158680B4 (de) * | 2001-11-30 | 2004-04-08 | Universitätsklinikum Hamburg-Eppendorf | Verfahren zur ex vivo-Expansion und -Differenzierung von multipotenten Stammzellen |
| US20050019910A1 (en) * | 2001-12-13 | 2005-01-27 | Mutsumi Takagi | Human cell culture medium and culture method |
| US7470538B2 (en) | 2002-12-05 | 2008-12-30 | Case Western Reserve University | Cell-based therapies for ischemia |
| US20060205071A1 (en) * | 2003-07-17 | 2006-09-14 | Gamida-Cell Ltd. | Methods for ex-vivo expanding stem/progenitor cells |
| US9074190B2 (en) * | 2003-10-07 | 2015-07-07 | Biomaster, Inc. | Cell differentiation of adipose-derived precursor cells |
| JP2005287479A (ja) | 2004-03-31 | 2005-10-20 | Kazuhisa Maeda | 組織幹細胞採取方法及びそれを利用した装置 |
| US20060134781A1 (en) * | 2004-12-07 | 2006-06-22 | Bacterin International, Inc. | Three-dimensional cell culture system |
| JP2006230316A (ja) | 2005-02-25 | 2006-09-07 | Japan Health Science Foundation | 瘢痕のない創傷治癒能を有する細胞およびその調製方法 |
| JPWO2006134951A1 (ja) * | 2005-06-13 | 2009-01-08 | 株式会社バイオマスター | 脂肪由来幹細胞の長期培養増殖法 |
| US7989205B2 (en) * | 2005-10-06 | 2011-08-02 | American Cryostem Corporation | Cell culture media, kits and methods of use |
| CZ301148B6 (cs) * | 2006-01-25 | 2009-11-18 | Univerzita Karlova V Praze | Zpusob pestování lidských mezenchymových kmenových bunek, zejména pro lécbu nehojících se fraktur, a bioreaktor k provádení tohoto zpusobu |
| US8337827B2 (en) * | 2006-02-16 | 2012-12-25 | Universite Libre de Bruxelies | Method for osteogenic differentiation of bone marrow stem cells (BMSC) and uses thereof |
| JP5155530B2 (ja) * | 2006-07-25 | 2013-03-06 | 株式会社カネカ | 成体幹細胞分離・培養システム |
| WO2008018190A1 (en) * | 2006-08-09 | 2008-02-14 | Biomaster, Inc. | Fat-derived neural crest cells |
| KR20110013450A (ko) * | 2008-05-07 | 2011-02-09 | 본 테라퓨틱스 소시에테아노님 | 간엽 줄기 세포 및 골-형성 세포 |
-
2009
- 2009-05-07 KR KR20107027373A patent/KR20110013450A/ko not_active Ceased
- 2009-05-07 CN CN2009801164561A patent/CN102016008A/zh active Pending
- 2009-05-07 EP EP09742123.4A patent/EP2291516B1/en active Active
- 2009-05-07 WO PCT/EP2009/055549 patent/WO2009135905A2/en not_active Ceased
- 2009-05-07 KR KR1020167013649A patent/KR20160065213A/ko not_active Ceased
- 2009-05-07 CA CA 2722625 patent/CA2722625A1/en not_active Abandoned
- 2009-05-07 BE BE2009/0286A patent/BE1018748A3/fr not_active IP Right Cessation
- 2009-05-07 US US12/991,120 patent/US9371515B2/en active Active
- 2009-05-07 AU AU2009245751A patent/AU2009245751B2/en not_active Ceased
- 2009-05-07 JP JP2011507925A patent/JP6097479B2/ja not_active Expired - Fee Related
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2013
- 2013-03-12 US US13/797,179 patent/US20140093480A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| JP6097479B2 (ja) | 2017-03-15 |
| JP2011520434A (ja) | 2011-07-21 |
| BE1018748A3 (fr) | 2011-08-02 |
| EP2291516B1 (en) | 2019-01-02 |
| AU2009245751B2 (en) | 2014-09-18 |
| EP2291516A2 (en) | 2011-03-09 |
| KR20160065213A (ko) | 2016-06-08 |
| JP2017099386A (ja) | 2017-06-08 |
| US20170290859A1 (en) | 2017-10-12 |
| US20110262404A1 (en) | 2011-10-27 |
| CN102016008A (zh) | 2011-04-13 |
| US20140093480A1 (en) | 2014-04-03 |
| CA2722625A1 (en) | 2009-11-12 |
| WO2009135905A2 (en) | 2009-11-12 |
| US9371515B2 (en) | 2016-06-21 |
| AU2009245751A1 (en) | 2009-11-12 |
| WO2009135905A3 (en) | 2010-02-25 |
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