KR20100091965A - 신규 아밀로이드 친화성 화합물 - Google Patents

신규 아밀로이드 친화성 화합물 Download PDF

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Publication number
KR20100091965A
KR20100091965A KR1020107010117A KR20107010117A KR20100091965A KR 20100091965 A KR20100091965 A KR 20100091965A KR 1020107010117 A KR1020107010117 A KR 1020107010117A KR 20107010117 A KR20107010117 A KR 20107010117A KR 20100091965 A KR20100091965 A KR 20100091965A
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KR
South Korea
Prior art keywords
group
substituent
pyridine
iodine
methylimidazo
Prior art date
Application number
KR1020107010117A
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English (en)
Korean (ko)
Inventor
시게유키 타니후지
다이사쿠 나카무라
신야 타카사키
유키 오쿠무라
Original Assignee
니혼 메디피직스 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 니혼 메디피직스 가부시키가이샤 filed Critical 니혼 메디피직스 가부시키가이샤
Publication of KR20100091965A publication Critical patent/KR20100091965A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
KR1020107010117A 2007-10-24 2008-10-24 신규 아밀로이드 친화성 화합물 KR20100091965A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007276826 2007-10-24
JPJP-P-2007-276826 2007-10-24

Publications (1)

Publication Number Publication Date
KR20100091965A true KR20100091965A (ko) 2010-08-19

Family

ID=40579598

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107010117A KR20100091965A (ko) 2007-10-24 2008-10-24 신규 아밀로이드 친화성 화합물

Country Status (9)

Country Link
US (1) US20100249418A1 (fr)
EP (1) EP2213672A4 (fr)
JP (1) JPWO2009054496A1 (fr)
KR (1) KR20100091965A (fr)
CN (1) CN101903381A (fr)
AU (1) AU2008314870A1 (fr)
CA (1) CA2703649A1 (fr)
TW (1) TW200918102A (fr)
WO (1) WO2009054496A1 (fr)

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TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
JP5238496B2 (ja) * 2006-05-19 2013-07-17 日本メジフィジックス株式会社 新規アミロイド親和性化合物
CN101501033B (zh) * 2006-06-21 2012-08-01 通用电气医疗有限公司 对淀粉状蛋白具有亲和性的化合物
EP2080526A4 (fr) * 2006-11-09 2012-11-07 Nihon Mediphysics Co Ltd Agent d'imagerie de diagnostic radioactif
EP2098523A4 (fr) * 2006-11-17 2011-09-21 Nihon Mediphysics Co Ltd Composés inédits présentant une affinité pour la substance amyloïde
CN101595108A (zh) * 2006-11-30 2009-12-02 日本医事物理股份有限公司 对淀粉状蛋白具有亲和性的新化合物
WO2008099800A1 (fr) 2007-02-13 2008-08-21 Nihon Medi-Physics Co., Ltd. Procédé de fabrication d'un agent d'imagerie de diagnostic par rayonnement
EP2213671A4 (fr) * 2007-10-26 2012-02-22 Nihon Mediphysics Co Ltd Nouveau composé présentant une affinité pour l'amyloïde
JPWO2009057576A1 (ja) * 2007-10-30 2011-03-10 日本メジフィジックス株式会社 新規アミロイド親和性化合物の使用及び製造方法
EP2216052A4 (fr) * 2007-10-30 2012-11-21 Nihon Mediphysics Co Ltd Utilisation d'un nouveau composé présentant une affinité pour les substances amyloïdes et procédé de production dudit composé
US9149546B2 (en) 2011-05-20 2015-10-06 Nihon Medi-Physics Co., Ltd. Compound having affinity for amyloid
WO2012176587A1 (fr) 2011-06-24 2012-12-27 日本メジフィジックス株式会社 Nouveau composé ayant une affinité pour l'amyloïde

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JP5238496B2 (ja) * 2006-05-19 2013-07-17 日本メジフィジックス株式会社 新規アミロイド親和性化合物
CN101501033B (zh) * 2006-06-21 2012-08-01 通用电气医疗有限公司 对淀粉状蛋白具有亲和性的化合物
CN101595108A (zh) * 2006-11-30 2009-12-02 日本医事物理股份有限公司 对淀粉状蛋白具有亲和性的新化合物
EP2213671A4 (fr) * 2007-10-26 2012-02-22 Nihon Mediphysics Co Ltd Nouveau composé présentant une affinité pour l'amyloïde
JPWO2009057576A1 (ja) * 2007-10-30 2011-03-10 日本メジフィジックス株式会社 新規アミロイド親和性化合物の使用及び製造方法
JPWO2009057578A1 (ja) * 2007-10-30 2011-03-10 日本メジフィジックス株式会社 新規アミロイド親和性化合物の使用及び製造方法
JP5774982B2 (ja) * 2008-05-19 2015-09-09 サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． イミダゾ［１，２−ａ］ピリジン化合物

Also Published As

Publication number Publication date
EP2213672A1 (fr) 2010-08-04
CA2703649A1 (fr) 2009-04-30
WO2009054496A1 (fr) 2009-04-30
EP2213672A4 (fr) 2012-05-02
TW200918102A (en) 2009-05-01
US20100249418A1 (en) 2010-09-30
AU2008314870A1 (en) 2009-04-30
CN101903381A (zh) 2010-12-01
JPWO2009054496A1 (ja) 2011-03-10

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