KR20100041849A - Cd200에 대한 항체와 면역 반응의 저해에서 이들의 용도 - Google Patents

Cd200에 대한 항체와 면역 반응의 저해에서 이들의 용도 Download PDF

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Publication number
KR20100041849A
KR20100041849A KR1020107003921A KR20107003921A KR20100041849A KR 20100041849 A KR20100041849 A KR 20100041849A KR 1020107003921 A KR1020107003921 A KR 1020107003921A KR 20107003921 A KR20107003921 A KR 20107003921A KR 20100041849 A KR20100041849 A KR 20100041849A
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Korean (ko)
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러셀 피. 로데르
수잔 파스 맥나이트
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알렉시온 파마슈티칼스, 인코포레이티드
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Publication of KR20100041849A publication Critical patent/KR20100041849A/ko
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
KR1020107003921A 2007-07-25 2008-07-25 Cd200에 대한 항체와 면역 반응의 저해에서 이들의 용도 Abandoned KR20100041849A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96202207P 2007-07-25 2007-07-25
US60/962,022 2007-07-25

Publications (1)

Publication Number Publication Date
KR20100041849A true KR20100041849A (ko) 2010-04-22

Family

ID=40001380

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107003921A Abandoned KR20100041849A (ko) 2007-07-25 2008-07-25 Cd200에 대한 항체와 면역 반응의 저해에서 이들의 용도

Country Status (9)

Country Link
US (3) US8252285B2 (cg-RX-API-DMAC7.html)
EP (1) EP2178561A1 (cg-RX-API-DMAC7.html)
JP (4) JP2010534243A (cg-RX-API-DMAC7.html)
KR (1) KR20100041849A (cg-RX-API-DMAC7.html)
AU (1) AU2008279619B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0814644A2 (cg-RX-API-DMAC7.html)
CA (1) CA2697159C (cg-RX-API-DMAC7.html)
MX (1) MX2010000981A (cg-RX-API-DMAC7.html)
WO (1) WO2009014745A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018199378A1 (ko) * 2017-04-27 2018-11-01 서울대학교 산학협력단 이종 각막 이식에서 항 cd20 단일클론항체 및 타클로리무스의 복합면역억제 방법

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010000981A (es) * 2007-07-25 2010-05-21 Alexion Pharma Inc Anticuerpos para cd200 y usos de los mismos para inhibir respuestas inmune.
NZ601580A (en) 2010-02-11 2014-11-28 Alexion Pharma Inc Therapeutic methods using anti-cd200 antibodies
CA2826453A1 (en) * 2011-02-03 2012-08-09 Alexion Pharmaceuticals, Inc. Use of an anti-cd200 antibody for prolonging the survival of allografts
EP2718321A4 (en) 2011-06-10 2015-01-28 Canada Minister Nat Defence ANTI-RICIN ANTIBODIES AND ITS USES
WO2012178137A1 (en) 2011-06-24 2012-12-27 Gillies Stephen D Light chain immunoglobulin fusion proteins and methods of use thereof
US9737598B2 (en) * 2014-06-30 2017-08-22 Regents Of The University Of Minnesota CD200 inhibitors and methods of use thereof
JP2018504104A (ja) * 2014-12-17 2018-02-15 セレクティスCellectis 非T細胞伝達ドメインを発現する阻害性キメラ抗原受容体(iCARまたはN−CAR)
EP3370763B1 (en) 2015-11-03 2024-04-10 Regents of the University of Minnesota Cd200 inhibitors and methods of use thereof
RU2769282C2 (ru) 2016-06-20 2022-03-30 Кимаб Лимитед Анти-PD-L1 и IL-2 цитокины
WO2018102594A1 (en) * 2016-12-01 2018-06-07 Alexion Pharmaceuticals, Inc. Methods of treating solid tumors with anti-cd200 antibodies
US11761963B2 (en) 2017-09-27 2023-09-19 Alexion Pharmaceuticals, Inc. Biomarker signature for predicting tumor response to anti-CD200 therapy
US11802154B2 (en) 2017-12-20 2023-10-31 Alexion Pharmaceuticals, Inc. Humanized anti-CD200 antibodies and uses thereof
US12139533B2 (en) 2017-12-20 2024-11-12 Alexion Pharmaceuticals, Inc. Liquid formulations of anti-CD200 antibodies
AU2020208192A1 (en) 2019-01-14 2021-08-05 Regents Of The University Of Minnesota CD200AR ligands for cancer immunotherapy
EP4296280A1 (en) 2022-06-21 2023-12-27 F. Hoffmann-La Roche AG Cd123 and cd200 as markers for the diagnosis and immune-eradication of leukemic stem cells (lscs)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223729B2 (en) * 1997-11-07 2007-05-29 Trillium Therapeutics Inc. Methods of treating allergy by administering a CD200 protein
ES2260852T3 (es) * 1997-11-07 2006-11-01 Trillium Therapeutics Inc. Metodos y composiciones para inmunomodulacion.
US20060057651A1 (en) * 2000-12-08 2006-03-16 Bowdish Katherine S Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
WO2004060295A2 (en) 2002-12-27 2004-07-22 Schering Corporation Methods of inducing and maintaining immune tolerance
PL2463305T3 (pl) * 2006-01-12 2017-02-28 Alexion Pharmaceuticals, Inc. Przeciwciała przeciw OX-2/CD200 i ich zastosowania
MX2010000981A (es) 2007-07-25 2010-05-21 Alexion Pharma Inc Anticuerpos para cd200 y usos de los mismos para inhibir respuestas inmune.
AU2008279618B2 (en) 2007-07-25 2014-05-22 Alexion Pharmaceuticals, Inc. Methods and compositions for treating autoimmune disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018199378A1 (ko) * 2017-04-27 2018-11-01 서울대학교 산학협력단 이종 각막 이식에서 항 cd20 단일클론항체 및 타클로리무스의 복합면역억제 방법

Also Published As

Publication number Publication date
BRPI0814644A2 (pt) 2015-01-27
CA2697159A1 (en) 2009-01-29
US20120321625A1 (en) 2012-12-20
AU2008279619B2 (en) 2013-11-14
CA2697159C (en) 2017-02-14
JP2015172090A (ja) 2015-10-01
US20100291085A1 (en) 2010-11-18
JP2016117762A (ja) 2016-06-30
WO2009014745A1 (en) 2009-01-29
US8252285B2 (en) 2012-08-28
US8637014B2 (en) 2014-01-28
EP2178561A1 (en) 2010-04-28
JP5926702B2 (ja) 2016-05-25
USRE46323E1 (en) 2017-02-28
AU2008279619A1 (en) 2009-01-29
JP2010534243A (ja) 2010-11-04
JP2013163695A (ja) 2013-08-22
MX2010000981A (es) 2010-05-21

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