KR20100024494A - 퀴나졸리논 화합물 및 이의 사용 방법 - Google Patents

퀴나졸리논 화합물 및 이의 사용 방법 Download PDF

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Publication number
KR20100024494A
KR20100024494A KR1020107001013A KR20107001013A KR20100024494A KR 20100024494 A KR20100024494 A KR 20100024494A KR 1020107001013 A KR1020107001013 A KR 1020107001013A KR 20107001013 A KR20107001013 A KR 20107001013A KR 20100024494 A KR20100024494 A KR 20100024494A
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KR
South Korea
Prior art keywords
chloro
compound
oxo
propyl
phenylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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KR1020107001013A
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English (en)
Korean (ko)
Inventor
지펭 리우
시드 엠. 알리
마크 에이. 에쉬웰
핑 이
유솅 관
시-청 응
로시오 펠마
댄 요하네스
Original Assignee
아르퀼 인코포레이티드
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Application filed by 아르퀼 인코포레이티드 filed Critical 아르퀼 인코포레이티드
Publication of KR20100024494A publication Critical patent/KR20100024494A/ko
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020107001013A 2007-06-22 2008-06-19 퀴나졸리논 화합물 및 이의 사용 방법 Withdrawn KR20100024494A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94583807P 2007-06-22 2007-06-22
US60/945,838 2007-06-22

Publications (1)

Publication Number Publication Date
KR20100024494A true KR20100024494A (ko) 2010-03-05

Family

ID=39846620

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107001013A Withdrawn KR20100024494A (ko) 2007-06-22 2008-06-19 퀴나졸리논 화합물 및 이의 사용 방법

Country Status (13)

Country Link
US (1) US8232285B2 (https=)
EP (1) EP2173724B1 (https=)
JP (1) JP2010530885A (https=)
KR (1) KR20100024494A (https=)
CN (1) CN101801937A (https=)
AU (1) AU2008268613A1 (https=)
BR (1) BRPI0813355A2 (https=)
CA (1) CA2704282A1 (https=)
IL (1) IL202740A0 (https=)
MX (1) MX2009013815A (https=)
TW (1) TW200918069A (https=)
WO (1) WO2009002808A2 (https=)
ZA (1) ZA201000183B (https=)

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WO2015051241A1 (en) 2013-10-04 2015-04-09 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
MX2021012208A (es) 2013-10-04 2023-01-19 Infinity Pharmaceuticals Inc Compuestos heterocíclicos y usos de los mismos.
US20150132575A1 (en) * 2013-11-14 2015-05-14 Honeywell International Inc. Luminescent fibers, articles including the same, and methods of forming the same
NZ724368A (en) 2014-03-19 2023-07-28 Infinity Pharmaceuticals Inc Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
WO2016054491A1 (en) 2014-10-03 2016-04-07 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
EP4585268A3 (en) 2015-09-14 2025-10-15 Twelve Therapeutics, Inc. Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same
US10759806B2 (en) 2016-03-17 2020-09-01 Infinity Pharmaceuticals, Inc. Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as PI3K kinase inhibitors
WO2017214269A1 (en) 2016-06-08 2017-12-14 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
TW201825465A (zh) 2016-09-23 2018-07-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201813963A (zh) 2016-09-23 2018-04-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201815787A (zh) 2016-09-23 2018-05-01 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
EP3790878A1 (en) * 2018-05-11 2021-03-17 The United States of America, as represented by the Secretary, Department of Health and Human Services Quinoline compounds and their preparation and use as antimalarial agents
CN113354590A (zh) * 2020-03-05 2021-09-07 宁波康柏睿格医药科技有限公司 拮抗nod1/2受体信号通路的喹唑啉酮类化合物

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Also Published As

Publication number Publication date
EP2173724B1 (en) 2012-12-05
WO2009002808A3 (en) 2009-07-23
WO2009002808A2 (en) 2008-12-31
CN101801937A (zh) 2010-08-11
BRPI0813355A2 (pt) 2014-12-30
ZA201000183B (en) 2011-03-30
US20090130097A1 (en) 2009-05-21
AU2008268613A1 (en) 2008-12-31
IL202740A0 (en) 2010-06-30
US8232285B2 (en) 2012-07-31
TW200918069A (en) 2009-05-01
MX2009013815A (es) 2010-03-01
JP2010530885A (ja) 2010-09-16
CA2704282A1 (en) 2008-12-31
EP2173724A2 (en) 2010-04-14

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20100115

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid