KR20090130019A - 톨-유사 수용체 3(ｔｌｒ３)의 제한적인 작용제 - Google Patents
톨-유사 수용체 3(ｔｌｒ３)의 제한적인 작용제 Download PDFInfo
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- KR20090130019A KR20090130019A KR1020097020751A KR20097020751A KR20090130019A KR 20090130019 A KR20090130019 A KR 20090130019A KR 1020097020751 A KR1020097020751 A KR 1020097020751A KR 20097020751 A KR20097020751 A KR 20097020751A KR 20090130019 A KR20090130019 A KR 20090130019A
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- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C12N2760/00011—Details
- C12N2760/12011—Bunyaviridae
- C12N2760/12211—Phlebovirus, e.g. Rift Valley fever virus
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- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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| EP (1) | EP2134172A4 (https=) |
| JP (1) | JP2010520284A (https=) |
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| NZ (1) | NZ579433A (https=) |
| WO (1) | WO2008109083A2 (https=) |
| ZA (1) | ZA200905954B (https=) |
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| WO2007067517A2 (en) | 2005-12-07 | 2007-06-14 | Hemispherx Biopharma | Dsrnas as influenza virus vaccine adjuvants or immuno-stimulants |
| WO2009102496A2 (en) * | 2008-02-15 | 2009-08-20 | Hemispherx Biopharma, Inc. | Selective agonist of toll-like receptor 3 |
| US8722874B2 (en) | 2008-10-23 | 2014-05-13 | Hemispherx Biopharma, Inc. | Double-stranded ribonucleic acids with rugged physico-chemical structure and highly specific biologic activity |
| AU2009308105B2 (en) * | 2008-10-23 | 2016-07-07 | Aim Immunotech Inc. | Double-stranded ribonucleic acids with rugged physico-chemical structure and highly specific biologic activity |
| US20100160413A1 (en) * | 2008-10-23 | 2010-06-24 | Hemispherx Biopharma, Inc. | Double-stranded ribonucleic acids with rugged physico-chemical structure and highly specific biologic activity |
| RS55861B1 (sr) * | 2008-10-31 | 2017-08-31 | Janssen Biotech Inc | Antagonisti toll-like receptora 3 |
| US9090897B2 (en) * | 2009-12-18 | 2015-07-28 | Bavarian Nordic A/S | Production of IFN-lambda by conventional dendritic cells |
| CN101780279B (zh) * | 2009-12-22 | 2012-07-11 | 中山大学中山眼科中心 | Toll-like receptor-3激动剂在制备促进伤口愈合的药物中的应用 |
| EP2558069A1 (en) | 2010-04-13 | 2013-02-20 | Novartis AG | Benzonapthyridine compositions and uses thereof |
| CA2802721C (en) * | 2010-06-25 | 2015-08-18 | Idera Pharmaceuticals, Inc. | Novel agonists of toll-like receptor 3 and methods of their use |
| US10105305B2 (en) | 2014-02-19 | 2018-10-23 | The Johns Hopkins University | Compositions and methods for promoting skin regeneration and hair growth |
| EP3321362A1 (en) | 2016-11-10 | 2018-05-16 | Centre Leon Berard | Tlr3 agonist for use for inducing apoptosis in senescent cancer cells |
| EP3558350A1 (en) | 2016-12-22 | 2019-10-30 | Intervet International B.V. | Eimeria vaccine with improved efficacy |
| CN112703011A (zh) | 2018-08-06 | 2021-04-23 | 国家医疗保健研究所 | 用于治疗癌症的方法和组合物 |
| WO2020232226A1 (en) | 2019-05-16 | 2020-11-19 | The Johns Hopkins University | Compositions and methods for skin rejuvenation |
| CN117320722A (zh) | 2021-04-28 | 2023-12-29 | 埃尼奥制药公司 | 使用fxr激动剂作为联合治疗强烈增强tlr3激动剂的作用 |
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| US6080726A (en) * | 1985-08-12 | 2000-06-27 | University Of Maryland | Anti-viral and immuno stimulator polynucleotide duplex and use thereof |
| US5063209A (en) * | 1985-08-26 | 1991-11-05 | Hem Research, Inc. | Modulation of aids virus-related events by double-stranded RNAs |
| IE72103B1 (en) * | 1987-08-12 | 1997-03-12 | Hem Res Inc | Promotion of host defense by systemic dsRNA treatment |
| US5683986A (en) * | 1987-08-12 | 1997-11-04 | Hemispherx Biopharma Inc. | Elaboration of host defense mediators into biological fluids by systemic dsRNA treatment |
| US5976800A (en) * | 1996-06-28 | 1999-11-02 | The Regents Of The University Of California | Enhancement of cancer cell death |
| GB0119346D0 (en) * | 2001-08-08 | 2001-10-03 | Bioclones Proprietary Ltd | Process for the maturation of dendritic cells |
| US20060211752A1 (en) * | 2004-03-16 | 2006-09-21 | Kohn Leonard D | Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression |
| CA2587676A1 (en) * | 2004-11-19 | 2006-05-26 | Institut Gustave Roussy | Improved treatment of cancer by double-stranded rna |
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| EP2134172A2 (en) | 2009-12-23 |
| ZA200905954B (en) | 2011-10-26 |
| EP2134172A4 (en) | 2011-06-01 |
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| US20100183638A1 (en) | 2010-07-22 |
| WO2008109083A2 (en) | 2008-09-12 |
| CA2680134A1 (en) | 2008-09-12 |
| NZ579433A (en) | 2012-05-25 |
| AU2008223446B2 (en) | 2012-02-02 |
| CN101652062A (zh) | 2010-02-17 |
| JP2010520284A (ja) | 2010-06-10 |
| WO2008109083A3 (en) | 2008-11-27 |
| AU2008223446A1 (en) | 2008-09-12 |
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