KR20090118925A - 아미노레불린산 및 그것의 유도체의 용도 - Google Patents

아미노레불린산 및 그것의 유도체의 용도 Download PDF

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Publication number
KR20090118925A
KR20090118925A KR1020097016703A KR20097016703A KR20090118925A KR 20090118925 A KR20090118925 A KR 20090118925A KR 1020097016703 A KR1020097016703 A KR 1020097016703A KR 20097016703 A KR20097016703 A KR 20097016703A KR 20090118925 A KR20090118925 A KR 20090118925A
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KR
South Korea
Prior art keywords
aminolevulinic acid
photodynamic therapy
acid ester
composition
side effects
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020097016703A
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English (en)
Korean (ko)
Inventor
한스 크리스티앙 울프
아슬락 고달
조 클라베네스
Original Assignee
포토큐어 에이에스에이
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Application filed by 포토큐어 에이에스에이 filed Critical 포토큐어 에이에스에이
Publication of KR20090118925A publication Critical patent/KR20090118925A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/00615-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0616Skin treatment other than tanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/065Light sources therefor
    • A61N2005/0651Diodes
    • A61N2005/0652Arrays of diodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662Visible light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662Visible light
    • A61N2005/0663Coloured light

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020097016703A 2007-01-11 2008-01-11 아미노레불린산 및 그것의 유도체의 용도 Ceased KR20090118925A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0700580.4A GB0700580D0 (en) 2007-01-11 2007-01-11 Use
GB0700580.4 2007-01-11

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020147014684A Division KR20140076641A (ko) 2007-01-11 2008-01-11 아미노레불린산 및 그것의 유도체의 용도

Publications (1)

Publication Number Publication Date
KR20090118925A true KR20090118925A (ko) 2009-11-18

Family

ID=37809842

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020097016703A Ceased KR20090118925A (ko) 2007-01-11 2008-01-11 아미노레불린산 및 그것의 유도체의 용도
KR1020147014684A Ceased KR20140076641A (ko) 2007-01-11 2008-01-11 아미노레불린산 및 그것의 유도체의 용도

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020147014684A Ceased KR20140076641A (ko) 2007-01-11 2008-01-11 아미노레불린산 및 그것의 유도체의 용도

Country Status (13)

Country Link
US (4) US8759396B2 (enExample)
EP (3) EP2120921B1 (enExample)
JP (2) JP5814508B2 (enExample)
KR (2) KR20090118925A (enExample)
CN (3) CN101631541A (enExample)
CA (2) CA2784250C (enExample)
DK (1) DK2120921T3 (enExample)
ES (2) ES2900528T3 (enExample)
GB (1) GB0700580D0 (enExample)
PL (1) PL2120921T3 (enExample)
PT (1) PT2120921E (enExample)
SI (1) SI2120921T1 (enExample)
WO (1) WO2008084241A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101254758B1 (ko) * 2011-02-28 2013-04-15 부산대학교병원 광역동치료의 광증감제로 사용하기 위한 이디티에이를 이용한 아미노레불리닉산 테트라머
KR101254752B1 (ko) * 2011-02-28 2013-04-15 부산대학교 산학협력단 광역동치료의 광증감제로 사용하기 위한 구연산을 이용한 아미노레불리닉산 트라이머
WO2015002347A1 (ko) * 2013-07-02 2015-01-08 제너럴바이오(주) 광역동 치료 후처치를 위한 칼란코에 추출물이 포함된 항산화 액상 조성물

Families Citing this family (25)

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US20110224598A1 (en) * 2010-03-12 2011-09-15 Daniel Barolet Radiant near infrared light emitting diode exposure as skin preparation
GB0900461D0 (en) * 2009-01-12 2009-02-11 Photocure Asa Photodynamic therapy device
CN102458388B (zh) * 2009-06-11 2016-09-28 光治疗Asa公司 半固体组合物及药物制品
JP2013521251A (ja) * 2010-03-01 2013-06-10 フォトキュア エイエスエイ 美容組成物
CN104152530B (zh) 2010-12-24 2017-09-19 爱科来株式会社 癌细胞的检测方法
CN102617378B (zh) * 2011-01-26 2016-04-27 上海泺安医药技术有限公司 一种2-(3’-氨基-2’-氧-丙基)丙二酸酯盐及制备
CN102179010B (zh) * 2011-05-27 2013-01-09 吉林大学 脑胶质瘤光动力直接照射治疗装置
WO2013092505A1 (en) 2011-12-19 2013-06-27 Photocure Asa Irradiation apparatus
WO2013111719A1 (ja) * 2012-01-26 2013-08-01 Sbiファーマ株式会社 光線力学的診断剤、及び、フォトブリーチング防止剤
US20140067024A1 (en) 2012-08-30 2014-03-06 Photocure Asa Dual panel photodynamic therapy lamp
GB201306369D0 (en) 2013-04-09 2013-05-22 Photocure As Irradiation device
BR112016014073A2 (pt) * 2013-12-20 2017-08-08 Galderma Res & Dev Tratamento fotodinâmico de pulso de pele fotodanificada
PL229756B1 (pl) 2014-11-12 2018-08-31 Tarchominskie Zaklady Farmaceutyczne Polfa Spólka Akcyjna Krem do stosowania w diagnostyce i terapii z zastosowaniem metody fotodynamicznej
JP6289666B2 (ja) * 2014-11-19 2018-03-07 シャープ株式会社 光線力学治療装置
US10603508B2 (en) 2015-10-15 2020-03-31 Dusa Pharmaceuticals, Inc. Adjustable illuminators and methods for photodynamic therapy and diagnosis
EP3851161A1 (en) 2015-10-15 2021-07-21 DUSA Pharmaceuticals, Inc. Adjustable illuminator for photodynamic therapy and diagnosis
AU2016372575B2 (en) 2015-12-17 2022-12-08 Photocure Asa Method of photodynamic therapy (PDT) for bladder cancer
US10632324B2 (en) 2017-04-27 2020-04-28 9127-4910 Quebec Inc. Method for the treatment of skin tissues
AU2018302103B2 (en) * 2017-07-17 2024-03-07 Sun Pharmaceutical Industries, Inc. Photodynamic therapy method for skin disorders
US10357567B1 (en) 2018-01-12 2019-07-23 Dusa Pharmaceuticals, Inc. Methods for photodynamic therapy
WO2020038583A1 (en) * 2018-08-23 2020-02-27 Biofrontera Bioscience Gmbh Photodynamic therapy comprising two light exposures at different wavelengths
WO2020218577A1 (ja) 2019-04-26 2020-10-29 ネオファーマジャパン株式会社 フラビウイルス感染症治療剤
AU2020303417B2 (en) * 2019-06-25 2025-08-28 Sun Pharmaceutical Industries, Inc. Methods for reducing pain during photodynamic therapy of actinic keratosis
WO2022014654A1 (ja) * 2020-07-15 2022-01-20 ネオファーマジャパン株式会社 アフリカ豚熱(African Swine Fever:ASF)の治療及び/又は予防剤
CN113620828B (zh) * 2021-08-17 2025-04-01 湖南复瑞生物医药技术有限责任公司 一种5-氨基酮戊酸酯化物、用途和农药组合物

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US5955490A (en) 1989-07-28 1999-09-21 Queen's University At Kingston Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US5079262A (en) 1989-07-28 1992-01-07 Queen's University At Kingston Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid
US5234940A (en) 1989-07-28 1993-08-10 Queen's University Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
US5422093A (en) 1989-07-28 1995-06-06 Queen's University Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
US7530461B2 (en) * 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
CZ291132B6 (cs) 1995-03-10 2002-12-11 Photocure Asa Estery kyselin 5-aminolevulových a farmaceutický prostředek s jejich obsahem
GB9700396D0 (en) * 1997-01-10 1997-02-26 Photocure As Photochemotherapeutic compositions
AUPQ044499A0 (en) 1999-05-19 1999-06-10 Commonwealth Scientific And Industrial Research Organisation Control of wool growth
GB0018528D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Compounds
GB0018527D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Composition
CA2422865C (en) * 2000-08-16 2012-10-16 The General Hospital Corporation D/B/A Massachusetts General Hospital Aminolevulinic acid photodynamic therapy for treating sebaceous gland disorders
US6723750B2 (en) * 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
WO2003086460A2 (en) 2002-04-05 2003-10-23 Candela Corporation High fluence rate activation of photosensitizers for dermatological applications
US20040048842A1 (en) * 2002-09-10 2004-03-11 Mcmillan Kathleen Method of treating skin disorders
AU2003301267A1 (en) 2002-10-18 2004-05-04 The Regents Of The University Of California Photodynamic therapy for ocular neovascularization
US20050209330A1 (en) 2004-03-22 2005-09-22 Syneron Medical Ltd. Method of treatment of skin
US20050209331A1 (en) 2004-03-22 2005-09-22 Syneron Medical Ltd. Method of treatment of skin
GB0406917D0 (en) 2004-03-26 2004-04-28 Photocure Asa Compounds
GB0424833D0 (en) * 2004-11-10 2004-12-15 Photocure Asa Method
GB0609809D0 (en) * 2006-05-17 2006-06-28 Photocure Asa Product

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101254758B1 (ko) * 2011-02-28 2013-04-15 부산대학교병원 광역동치료의 광증감제로 사용하기 위한 이디티에이를 이용한 아미노레불리닉산 테트라머
KR101254752B1 (ko) * 2011-02-28 2013-04-15 부산대학교 산학협력단 광역동치료의 광증감제로 사용하기 위한 구연산을 이용한 아미노레불리닉산 트라이머
WO2015002347A1 (ko) * 2013-07-02 2015-01-08 제너럴바이오(주) 광역동 치료 후처치를 위한 칼란코에 추출물이 포함된 항산화 액상 조성물

Also Published As

Publication number Publication date
US20100137439A1 (en) 2010-06-03
DK2120921T3 (en) 2015-08-24
WO2008084241A3 (en) 2008-09-18
ES2546381T3 (es) 2015-09-23
WO2008084241A2 (en) 2008-07-17
CA2675334A1 (en) 2008-07-17
JP5827702B2 (ja) 2015-12-02
PT2120921E (pt) 2015-09-30
US20150150972A1 (en) 2015-06-04
EP2754439A2 (en) 2014-07-16
US20160030565A1 (en) 2016-02-04
ES2900528T3 (es) 2022-03-17
SI2120921T1 (sl) 2015-10-30
CN104069493A (zh) 2014-10-01
JP2014094963A (ja) 2014-05-22
JP2010515714A (ja) 2010-05-13
CN104524576A (zh) 2015-04-22
US10543272B2 (en) 2020-01-28
EP2754439A3 (en) 2014-10-01
EP2120921A2 (en) 2009-11-25
CA2675334C (en) 2014-02-25
EP2120921B1 (en) 2015-06-17
CA2784250A1 (en) 2008-07-17
CA2784250C (en) 2016-03-15
GB0700580D0 (en) 2007-02-21
CN101631541A (zh) 2010-01-20
EP2754439B1 (en) 2021-10-13
JP5814508B2 (ja) 2015-11-17
KR20140076641A (ko) 2014-06-20
US20130090592A1 (en) 2013-04-11
PL2120921T3 (pl) 2015-12-31
US8759396B2 (en) 2014-06-24
EP2659888A1 (en) 2013-11-06

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