KR20090094465A - 선택적 ａ2ａ 수용체 안타고니스토로서의 8-알키닐잔틴 유도체 - Google Patents

선택적 ａ2ａ 수용체 안타고니스토로서의 8-알키닐잔틴 유도체 Download PDF

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Publication number
KR20090094465A
KR20090094465A KR1020097015362A KR20097015362A KR20090094465A KR 20090094465 A KR20090094465 A KR 20090094465A KR 1020097015362 A KR1020097015362 A KR 1020097015362A KR 20097015362 A KR20097015362 A KR 20097015362A KR 20090094465 A KR20090094465 A KR 20090094465A
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KR
South Korea
Prior art keywords
methyl
alkyl
ynyl
prop
dihydropurine
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KR1020097015362A
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English (en)
Korean (ko)
Inventor
크리슈타 뮐러
외르크 호케마이어
니콜라이 츠베트코프
요아힘 부르빌
Original Assignee
슈바르츠 파르마 악티엔게젤샤프트
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41294864&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20090094465(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP06026739A external-priority patent/EP1939197A1/en
Application filed by 슈바르츠 파르마 악티엔게젤샤프트 filed Critical 슈바르츠 파르마 악티엔게젤샤프트
Publication of KR20090094465A publication Critical patent/KR20090094465A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020097015362A 2006-12-22 2007-12-19 선택적 ａ2ａ 수용체 안타고니스토로서의 8-알키닐잔틴 유도체 KR20090094465A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP06026739.0 2006-12-22
EP06026739A EP1939197A1 (en) 2006-12-22 2006-12-22 8-ethinylxanthine derivatives as selective A2A receptor antagonists
US94524807P 2007-06-20 2007-06-20
US60/945,248 2007-06-20

Publications (1)

Publication Number Publication Date
KR20090094465A true KR20090094465A (ko) 2009-09-07

Family

ID=41294864

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097015362A KR20090094465A (ko) 2006-12-22 2007-12-19 선택적 ａ2ａ 수용체 안타고니스토로서의 8-알키닐잔틴 유도체

Country Status (7)

Country Link
JP (1) JP2010513353A (es)
KR (1) KR20090094465A (es)
CL (1) CL2007003778A1 (es)
DO (1) DOP2009000145A (es)
MX (1) MX2009006346A (es)
PE (1) PE20081543A1 (es)
TW (1) TW200848421A (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE176470T1 (de) * 1990-10-18 1999-02-15 Kyowa Hakko Kogyo Kk Xanthinderivate
CA2093403C (en) * 1992-04-08 1999-08-10 Fumio Suzuki Therapeutic agent for parkinson's disease
JP2613355B2 (ja) * 1992-09-28 1997-05-28 協和醗酵工業株式会社 パーキンソン氏病治療剤
WO1994025462A1 (en) * 1993-05-03 1994-11-10 The United States Of America, Represented By The 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists
DE69526822T2 (de) * 1994-02-23 2003-01-23 Kyowa Hakko Kogyo K.K., Tokio/Tokyo Xanthin-derivate

Also Published As

Publication number Publication date
CL2007003778A1 (es) 2009-03-27
MX2009006346A (es) 2010-03-03
JP2010513353A (ja) 2010-04-30
DOP2009000145A (es) 2009-07-15
PE20081543A1 (es) 2009-01-04
TW200848421A (en) 2008-12-16

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