MX2009006346A - Derivados de 8-etinilxantina como antagonistas de receptores de a2a selectivos. - Google Patents
Derivados de 8-etinilxantina como antagonistas de receptores de a2a selectivos.Info
- Publication number
- MX2009006346A MX2009006346A MX2009006346A MX2009006346A MX2009006346A MX 2009006346 A MX2009006346 A MX 2009006346A MX 2009006346 A MX2009006346 A MX 2009006346A MX 2009006346 A MX2009006346 A MX 2009006346A MX 2009006346 A MX2009006346 A MX 2009006346A
- Authority
- MX
- Mexico
- Prior art keywords
- ethinylxanthine
- selective
- derivatives
- receptor antagonists
- dopamine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se revelan compuestos novedosos de la fórmula general (la) y sus sales, isómeros, diastereómeros o enantiómeros de los mismos farmacéuticamente aceptables (la) (ver fórmula (Ia)) y su uso como medicamentos, por ejemplo, en el tratamiento de trastornos del movimiento relacionados con dopamina.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06026739A EP1939197A1 (en) | 2006-12-22 | 2006-12-22 | 8-ethinylxanthine derivatives as selective A2A receptor antagonists |
US94524807P | 2007-06-20 | 2007-06-20 | |
PCT/EP2007/011172 WO2008077557A1 (en) | 2006-12-22 | 2007-12-19 | 8-ethinylxanthine derivatives as selective a2a receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009006346A true MX2009006346A (es) | 2010-03-03 |
Family
ID=41294864
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009006346A MX2009006346A (es) | 2006-12-22 | 2007-12-19 | Derivados de 8-etinilxantina como antagonistas de receptores de a2a selectivos. |
Country Status (7)
Country | Link |
---|---|
JP (1) | JP2010513353A (es) |
KR (1) | KR20090094465A (es) |
CL (1) | CL2007003778A1 (es) |
DO (1) | DOP2009000145A (es) |
MX (1) | MX2009006346A (es) |
PE (1) | PE20081543A1 (es) |
TW (1) | TW200848421A (es) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992006976A1 (fr) * | 1990-10-18 | 1992-04-30 | Kyowa Hakko Kogyo Co., Ltd. | Derive de xanthine |
CA2093403C (en) * | 1992-04-08 | 1999-08-10 | Fumio Suzuki | Therapeutic agent for parkinson's disease |
JP2613355B2 (ja) * | 1992-09-28 | 1997-05-28 | 協和醗酵工業株式会社 | パーキンソン氏病治療剤 |
AU6781194A (en) * | 1993-05-03 | 1994-11-21 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists |
US5703085A (en) * | 1994-02-23 | 1997-12-30 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivatives |
-
2007
- 2007-12-19 MX MX2009006346A patent/MX2009006346A/es not_active Application Discontinuation
- 2007-12-19 JP JP2009541873A patent/JP2010513353A/ja active Pending
- 2007-12-19 KR KR1020097015362A patent/KR20090094465A/ko not_active Application Discontinuation
- 2007-12-21 TW TW096149381A patent/TW200848421A/zh unknown
- 2007-12-21 CL CL2007003778A patent/CL2007003778A1/es unknown
-
2008
- 2008-01-02 PE PE2008000028A patent/PE20081543A1/es not_active Application Discontinuation
-
2009
- 2009-06-17 DO DO2009000145A patent/DOP2009000145A/es unknown
Also Published As
Publication number | Publication date |
---|---|
KR20090094465A (ko) | 2009-09-07 |
JP2010513353A (ja) | 2010-04-30 |
TW200848421A (en) | 2008-12-16 |
PE20081543A1 (es) | 2009-01-04 |
CL2007003778A1 (es) | 2009-03-27 |
DOP2009000145A (es) | 2009-07-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2008077557A8 (en) | 8-ethinylxanthine derivatives as selective a2a receptor antagonists | |
EA017278B9 (ru) | Соединения азаиндазола и способы применения | |
MY148429A (en) | Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with benzyl groups, method for producing drugs containing said compounds and use thereof | |
NO20084129L (no) | Pyridin(3,4-B)Pyrazinoner | |
TNSN08326A1 (en) | Azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments | |
WO2008012622A3 (en) | Azabenzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor | |
MX2009004662A (es) | Compuestos de pirazolina como antagonistas receptores de mineralocorticoides. | |
MX2012004848A (es) | Compuestos heterociclicos triciclicos. | |
MX2009000169A (es) | Derivados de purinona como agonistas de hm74a. | |
GEP20125538B (en) | 2,3-dihydrobenzo(1,4) dioxin-2-ylmethyl derivatives as alpha2c antagonists for use in the treatment of peripheric and central nervous system diseases | |
NO20076695L (no) | Nye MCHR1-antagonister og deres anvendelse for behandling av MCHR1-medierte tilstander og forstyrrelser | |
PL1807434T3 (pl) | Tienopirydyny jako allosteryczne środki wzmacniające receptor M4 muskarynowy | |
MXPA06009475A (es) | Derivados de quinazolina y usos terapeuticos de los mismos. | |
MX2007006387A (es) | Derivados de piridina 3-substituidos como antagonistas h3. | |
MY149854A (en) | Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments | |
MX2010006230A (es) | Derivados de arilamida substituidos con triazol y su uso como antagonistas de receptor purinergico p2x3 y/o p2x2/3. | |
DE602006018713D1 (de) | Als agonisten für den nikotinischen acetylcholinrezeptor geeignete azabicycloalkanderivate | |
ATE496918T1 (de) | Als a2b-adenosinrezeptorantagonisten geeignete 5- phenyl-6-pyridin-4-yl-1,3-dihydro-2h-imidazoä4, - büpyridin-2-onderivate | |
MX2009013501A (es) | Compuestos piperidinicos y sus usos. | |
JO3319B1 (ar) | مركبات 3- (ايميدازول) - بيرازولو (3,4 - b ) بيريدين | |
NO20080033L (no) | Kinolinderivater som NK3-antagonister | |
ZA200709090B (en) | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility | |
ZA200709094B (en) | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility | |
NO20065551L (no) | Anvendelse av opoid reseptor antagonistforbindelser for forhindring og/eller behandling av sykdommer assosiert med malet calcineurin | |
ZA200709096B (en) | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |