KR20080085035A - 암 치료를 위해 감마-방사선 조사와 병용되는 ｔｐｐ ｉｉ저해제의 용도 - Google Patents
암 치료를 위해 감마-방사선 조사와 병용되는 ｔｐｐ ｉｉ저해제의 용도 Download PDFInfo
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- KR20080085035A KR20080085035A KR1020087017003A KR20087017003A KR20080085035A KR 20080085035 A KR20080085035 A KR 20080085035A KR 1020087017003 A KR1020087017003 A KR 1020087017003A KR 20087017003 A KR20087017003 A KR 20087017003A KR 20080085035 A KR20080085035 A KR 20080085035A
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- phenyl
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- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
- 231100000041 toxicology testing Toxicity 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
- 230000026683 transduction Effects 0.000 description 1
- 125000001425 triazolyl group Chemical group 0.000 description 1
- IMNIMPAHZVJRPE-UHFFFAOYSA-N triethylenediamine Chemical compound C1CN2CCN1CC2 IMNIMPAHZVJRPE-UHFFFAOYSA-N 0.000 description 1
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- 230000006663 ubiquitin-proteasome pathway Effects 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
- A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Organic Chemistry (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75908806P | 2006-01-13 | 2006-01-13 | |
| US60/759,088 | 2006-01-13 |
Publications (1)
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|---|---|
| KR20080085035A true KR20080085035A (ko) | 2008-09-22 |
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Family Applications (1)
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| KR1020087017003A Withdrawn KR20080085035A (ko) | 2006-01-13 | 2007-01-15 | 암 치료를 위해 감마-방사선 조사와 병용되는 ｔｐｐ ｉｉ저해제의 용도 |
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| US (2) | US20100168038A1 (https=) |
| EP (2) | EP1971357A2 (https=) |
| JP (2) | JP2009523156A (https=) |
| KR (1) | KR20080085035A (https=) |
| CN (1) | CN101370509A (https=) |
| AU (1) | AU2007204314A1 (https=) |
| CA (1) | CA2636533A1 (https=) |
| WO (2) | WO2007080194A2 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2009000297A1 (en) * | 2007-06-25 | 2008-12-31 | Oncoreg Ab | Tpp ii inhibitors for use in combination with chemotherapy for the treatment of cancer |
| EP2170364A2 (en) * | 2007-06-25 | 2010-04-07 | Oncoreg AB | Tpp ii inhibitors for use in the treatment of autoimmune and inflammatory diseases and transplant rejection |
| US8779002B2 (en) * | 2007-10-15 | 2014-07-15 | Salk Institute For Biological Studies | Methods for treating a variety of diseases and conditions, and compounds useful therefor |
| MX2012006877A (es) | 2009-12-18 | 2012-08-31 | Idenix Pharmaceuticals Inc | Inhibidores de virus de hepatitis c de arileno o heteroarileno 5, 5 - fusionado. |
| WO2011159685A2 (en) * | 2010-06-16 | 2011-12-22 | The Regents Of The University Of Michigan | Inhibition of wdr5 interaction with its binding partners and therapeutic methods |
| AU2011348220B2 (en) * | 2010-12-22 | 2017-09-07 | The Salk Institute For Biological Studies | Cyclic CRF antagonist peptides |
| DK3049428T3 (en) | 2013-09-23 | 2019-03-04 | Dr August Wolff Gmbh & Co Kg Arzneimittel | ANTI-INFLAMMATORY TRIPEPTIDES |
| EP3171941B1 (en) * | 2014-07-24 | 2021-03-24 | Naurex Inc. | N-methyl-d-aspartate receptor modulators and methods of making and using same |
| CN111603560A (zh) * | 2020-06-22 | 2020-09-01 | 泉州台商投资区秋鑫茶业有限公司 | 茶叶γ-氨基丁酸在肿瘤放射治疗上的应用 |
| BR112023018676A2 (pt) | 2021-03-18 | 2023-10-10 | Seagen Inc | Conjugado anticorpo-fármaco, composição farmacêutica, métodos de tratamento de uma doença ou condição e de um câncer, e, composição de conjugado ligante-fármaco |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| MC2306A1 (fr) * | 1990-08-22 | 1993-09-27 | Syntello Vaccine Dev Kb | Peptides bloquant les infections par le virus de l'immunodeficience humaine et methode de leur utilisation |
| US5627035A (en) * | 1990-08-22 | 1997-05-06 | Syntello Vaccine Development Ab | Peptides that block human immunodeficiency virus and methods of use thereof |
| US6335360B1 (en) * | 1997-12-23 | 2002-01-01 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Tripeptidyl peptidase inhibitors |
| US6258932B1 (en) * | 1999-08-09 | 2001-07-10 | Tripep Ab | Peptides that block viral infectivity and methods of use thereof |
| DE10105039A1 (de) * | 2001-02-05 | 2002-08-08 | Tell Pharm Ag Hergiswil | Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
| WO2003024995A1 (en) * | 2001-09-19 | 2003-03-27 | Tripep Ab | Molecules that block viral infectivity and methods of use thereof |
| US20040097422A1 (en) * | 2002-06-14 | 2004-05-20 | Karl Munger | Methods of use for tripeptidyl peptidase II inhibitors as anticancer agents |
| EP1716247A1 (en) * | 2004-01-31 | 2006-11-02 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with tripeptidyl-peptidase 2 (tpp2) |
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- 2007-01-15 WO PCT/EP2007/050364 patent/WO2007088099A2/en not_active Ceased
- 2007-01-15 KR KR1020087017003A patent/KR20080085035A/ko not_active Withdrawn
Also Published As
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| WO2007088099A2 (en) | 2007-08-09 |
| WO2007080194A3 (en) | 2008-02-14 |
| JP2009523156A (ja) | 2009-06-18 |
| WO2007088099A3 (en) | 2007-11-08 |
| EP1971357A2 (en) | 2008-09-24 |
| JP2009523157A (ja) | 2009-06-18 |
| US20100168038A1 (en) | 2010-07-01 |
| AU2007204314A1 (en) | 2007-07-19 |
| CA2636533A1 (en) | 2007-07-19 |
| EP2160196A2 (en) | 2010-03-10 |
| US20090227521A1 (en) | 2009-09-10 |
| WO2007080194A2 (en) | 2007-07-19 |
| CN101370509A (zh) | 2009-02-18 |
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