KR20070051260A - Herbal composition - Google Patents

Abstract

The present invention is a tuja (tuja oxydentalis); American Zigong (Pittoraca decandra); Fragrance violets (viola odorata); Red shamrock (tripoleum pratense); Celandine (Kellydonium Mazu); And an extract from Calendula (Calendula Offinalilis); A formulation containing said herbal composition; And the use of said herbal composition for the prevention and / or treatment of skin diseases and / or conditions.

Tuja, American Lichen, Scent Violet, Red Shamrock, Celandine, Calendula, Herbal Composition

Description

Herb composition {HERBAL COMPOSITION}

The present invention relates to herbal compositions. In particular, the present invention relates to herbal compositions suitable for the treatment of various skin diseases and / or conditions.

The upper skin surface consists of various layers including the epidermis, dermis and subcutaneous. Environmental exposure can cause discoloration, pigmentation and other changes in the upper layer of the skin. Changes include aging and sun spots, freckles, melanoma, blemishes and other skin diseases and / or abnormalities.

Sun spots and other skin discolorations are thought to be caused by cumulative sun exposure. Areas of the body where sun spots are prone to occur are the scalp, neck, face, ears, back of the hand and forearms. Once sun spots appear, they tend not to disappear without treatment, regardless of the degree of sun protection that is subsequently taken.

Freckles are one of the most common skin discolorations in the population. Sun-induced freckles are medium brown in color and are usually wider and darker than natural freckles. The edges of sun-induced freckles are also irregular in shape, but are generally uniform in pigment throughout the lesion. Sun-induced freckles have been associated with non-melanoma and melanoma skin tumors.

Melanoma is a malignant tumor originating from melanocytes or cells producing melanin pigments that color the skin. Most melanoma is black or brown. However, melanoma sometimes stops pigment production. In this case, the melanoma no longer darkens, but the skin is colored pink, red or purple.

Blemishes are skin diseases that manifest themselves as brown patches on the face of an adult. Usually it affects both sides of the face. The most common related sites are the cheeks, the comparison, the forehead and the upper lip. Spots usually appear in women, but can also occur in men. Dark-skinned races tend to show more signs than other races.

Actinic keratosis and actinic keratosis are both types of sun-induced skin abnormalities. Both types of keratosis have scaly skin surfaces or form hard and thick ridges. The base of keratosis can be light or dark tan, pink, red, or a combination of these colors. Keratinosis can produce rough, dry patches on the skin, which in turn irritates and reddens the surrounding area.

Actinic keratosis is often a precancerous keratinous lesion, usually caused as a result of frequent exposure to sunlight. People with white, blond or red hair are particularly susceptible to actinic keratosis. People with dark skin are rarely affected. Actinic keratosis is often pink, with poor edges and often peels off like a scale or feels hard and thick when touched.

Sun keratosis is more common in the population. Sun keratosis is usually brown in color and sometimes resembles a wart. It is usually not considered to be precancerous.

Sunbeam keratosis is gradual and usually can range from 1/8 to 1/4 in. Sun keratosis often appears on parts of the body that are exposed to sunlight, such as the face, ears, scalp, neck, back of the hands, forearms, shoulders, and lips.

If left untreated, sun keratosis grows large and invades the surrounding tissues and, in rare cases, metastasizes to internal organs. Actinic keratosis appears to be easier to metastasize to internal organs.

Current orthodox treatments for the aforementioned skin diseases include the use of cryotherapy (freezing), cauterization (bearing), surgical resection (cutting) or esclorotic (erosive) applicators, creams and lotions.

The orthodox treatment is invasive, recovery can be painful and usually causes scarring. If caustic agents are used, care should be taken to avoid contact with healthy skin as blisters may occur. Accordingly, there is a need to provide improved therapies for treating skin diseases and / or abnormalities, or at least provide alternative treatment options that are useful to the public.

Summary of the Invention

According to a first aspect of the invention, there is provided a herbal composition comprising an extract from:

Tuja (tuja oxydentalis);

American Zigong (Pittoraca decandra);

Fragrance violets (viola odorata);

Red shamrock (tripoleum pratense);

Celandine (Kellydonium Mazu); And

Calendula (Calendula Offisinalis).

The herbal composition is iris (Iris Versicala), rake (gallium afariine), Goldenseal (Hydrastis canadensis), Sasapras (Sasapras alvidum), Yellow Dog (Lumex Crispers), Eki Nasea (Echinacea Angustifolia or Purpurea), Myrrh (Comipora Mall Mall), Pasqueflower (Anemone Fulsatilla), Aloe (Aloe Vera), Garlic (Alium Sativa), U.S. ), Hyunsam (Skropularia nodosa), Nettle (Eurica dioka), Pile water (Ranulculus picaria), Hypericum (Hyperricum perforatum), Corydalis (Pugaria officinalis) ), Slippery Elm (Ulmnus Pulva), Hemomyelum (Santinaria canadensis), Burdock (Arcium Rapha), Ginger (Gingerberg Offisinalis), and St. Mary's Thistle (Silybum Marianum) It may also include one or more extracts.

A second aspect of the present invention provides the above methods of prophylaxis and / or treatment, comprising administering a therapeutically effective amount of a herbal composition as defined above to a patient in need of prophylaxis and / or treatment of skin diseases and / or conditions.

A third aspect of the present invention provides the use of a herbal composition as defined above for the manufacture of a medicament for the prophylaxis and / or treatment of skin diseases and / or conditions.

A fourth aspect of the present invention provides the use of a herbal composition as defined above for the prophylaxis and / or treatment of skin diseases and / or conditions.

A fifth aspect of the present invention provides a herbal composition as defined above for use in the prophylaxis and / or treatment of skin diseases and / or conditions.

A sixth aspect of the present invention provides an agent comprising the herbal composition as defined above for the prophylaxis and / or treatment of skin diseases and / or conditions.

The herbal composition may be administered with one or more carriers for convenience. Thus, the seventh aspect of the present invention provides a herbal composition as defined above with one or more carriers.

The herbal composition is suitably administered topically and / or orally.

In this specification, unless otherwise indicated, for purposes of expressing a contextual terminology or a required implementation, the words "comprising" and the like are intended to be counted, that is, the presence of the described features is specified, but various In embodiments it is used in the sense that it does not exclude the presence or addition of additional features.

As used herein, the singular forms "a" and "the" are to be understood to include the plural aspects unless the context clearly dictates otherwise. Thus, for example, reference to “extract” includes not only a single extract but also two or more extracts and the like.

As used herein, the term "extract" should take the broadest possible meaning. "Extracts" may include, for example, tinctures, fluid extracts or solid extracts, tars and infused oils.

The herbal composition may comprise one or more different kinds of extracts, for example extracts in the form of tinctures, tars and leaching oils. Furthermore, the different herbs can be processed to form extracts by different means. Similarly, the herbal composition may comprise a mixture of extracts of two or more types of specific herbs.

Tinctures can be prepared from water based infusion and decoction. Alternative bases for the extract include acetact (to make vinegar extract), glycetact (to make glycerin extract), mel (to make honey extract), oxymel (honey and vinegar), or syrup (sugar To prepare an extract).

Tinctures are prepared by methods well known in the art. However, fresh plant tinctures are prepared simply by first obtaining air dried herbs as is known in the art. The dried herbs are then further dried in an oven at a temperature of 60 to 70 ° C. The oven dried herbs are then suspended in solution in a storage container. In a preferred form, the solution is a mixture of alcohol and water. To make up a 1: 5 tincture, 75 grams of oven dried herbs are suspended in 375 ml of the solution in a storage container (herb weight x 5 to obtain a ratio of 1: 5). The storage container is left to stand for about six weeks and periodically shaken. The mixture is then filtered and the recovered solution provides the tincture agent used.

Other herbal extraction methods are well known in the art. For example, tinctures can be prepared using low temperature leaching techniques.

The tincture can also be purchased in a ready-to-use formulation from a herb supplier, for example MediHerb Pty Ltd (124 McEvoy Street, Warwick, Queensland 4370, Australia).

Leachate oil can be prepared by brewing or macering the herb in oil. Boiling or softening the herbs in oil dissolves the herbs, which makes the resulting leach oils particularly suitable for topical application.

The oil used in the preparation of the leach oil may be a nonvolatile oil or a vegetable oil. Nonvolatile oils are nonvolatile animal or vegetable oils.

Examples of nonvolatile and vegetable oils include almond oil (including sweet almond oil), coconut oil, corn oil, peanut oil, olive oil (extra virgin olive oil), safflower oil, sesame oil, soybean oil, castor oil, malt oil and There is cod liver oil.

Low temperature compressed oils are particularly preferred. Processes for the preparation of cold press oils are well known in the art. In general, the method includes a simple milling and filtration process.

The leaching process generally includes the following steps:

• wither the herbal plant material overnight;

Placing the withered herbal plant material in a container, eg a jar, covered with a selected oil;

Cover the jar with a lid and gently shake to remove any bubbles around the herbal plant material;

Remove the lid from the jar and cover the jar with calico to allow moisture to leak out but prevent foreign objects such as dust and insects from falling into the oil and herb plant material mixture;

Put the jar in a warm place for 2-3 weeks, covered with a brown paper bag to block light;

The oil and herb plant material mixture is filtered through a muslin or filter paper into a second jar and left to rest for 1 week to sink any water from the herb plant material to the bottom;

Pour out the oil and allow it to stand still so that no moisture remains under the oil;

Pour out the leach oil and store it in a cool place in a dark glass container.

To prepare a thicker oil leachate, plenty of fresh herbs are added to the leachate and the process is repeated.

Dried herbs can be used in the same way.

This general leaching process can be used to produce various oils.

Tar is a very thick decoction and is further reduced by evaporation.

The extract can be prepared from any part of the herb plant, for example leaves, roots, flowers, bark, stems or rhizomes, seeds and fruits. Usually, however, certain parts of the herb plant are used to prepare the extract.

Tusa extract is usually prepared from the leaves. In a preferred embodiment of the present invention, the tuja extract is prepared as a tincture agent. The herbal composition preferably comprises about 0.5 to about 20% of a tuza extract, more preferably about 6 to about 10% of a tuza extract, and most preferably about 8% of a tuza extract.

US pore extracts are usually prepared from roots. In a preferred embodiment of the present invention, the US Pore Extract is prepared as a tincture agent. The herbal composition preferably comprises about 1 to about 20% of the US pore extract, more preferably about 14 to about 18% of the US pore extract, and most preferably about 16% of the US pore extract.

Fragrance violets are usually made from leaves. In a preferred embodiment of the present invention, the fragrant violet extract is prepared as a tincture agent. The herbal composition preferably comprises about 0.5 to about 12% of a fragrant violet extract, more preferably about 6 to about 10% of a fragrant violet extract, and most preferably about 8% of a fragrant violet extract.

Red shamrock extracts are usually prepared from flowers. In a preferred embodiment of the present invention, the red shamrock extract is prepared as tar. When the red shamrock extract is in the form of tar, the herbal composition is preferably about 1 to about 30% red shamrock extract, more preferably about 14 to about 18% red shamrock extract, and most preferably about Contains 16% red shamrock extract. The red shamrock extract may also be in the form of tinctures. When the herbal extract is in the form of a tincture, the herbal composition is preferably about 0.5 to about 20% red shamrock extract, more preferably about 2 to about 6% red shamrock extract, and most preferably about 4% red shamrock extract.

Celandine extract is usually prepared from the leaves. In a preferred embodiment of the present invention, the celandine extract is prepared as a tincture agent. The herbal composition preferably comprises about 0.2 to about 10% celandine extract, more preferably about 3 to about 4% celandine extract, and most preferably about 2% celandine extract.

Calendula extract is usually prepared from flowers. In a preferred form of the invention, the calendula extract is leached in oil. However, the calendula extract can also be prepared as a tincture agent. The herbal composition preferably comprises about 1 to about 16% calendula extract, more preferably about 6 to about 10% calendula extract, and most preferably about 8% calendula extract.

Table 1 illustrates the herbal composition of a preferred embodiment of the present invention.

Generic name Authorized Name Hub part Formulation Tuja Tuja Occidentalis leaf Tincture American seat ball Pitolaca Decandra Root Tincture Fragrance violet Viola odorata leaf Tincture Red shamrock Tripoleum Pratense Flower tar celandine Kellydonium Mazu leaf Tincture Calendula Calendula Officinalis Flower Leaching oil

In addition to the aforementioned herbal extracts, the herbal composition may also include one or more additional herbal extracts, which further may support the prevention and / or treatment of skin diseases and / or conditions. Examples include Iris (Iris Versicala), Rake (Gallium Aparine), Goldenseal (Hyrastis canadensis), Sasapras (Sasapras alvidum), Yellow Dog (Lumex Crispers), Echinacea (Echinacea Angustifolia or Purpurea), Myrrh (Comipora Mall Mall), Pasqueflower (Anemone Fulsatilla), Aloe (Aloe Vera), Garlic (Alium Sativa), U.S. Genus (Geranium Maculatum), Hyunsam (Skropularia nodosa), Nettle (Eurica dioka), Pylon (Ranulculus picaria), Hypericum (Hypericum perforatum), Corydalis (Pugaria Officinalis), One or more of Slippery Elm (Ulmner's Pulva), Hemomyelum (Santinaria canadensis), Burdock (Arcium Rapha), Ginger (Gingerberg Offisinalis), and St. Mary's Thistle (Siliboom Marianum) There is an extract.

The herbal composition may comprise from about 0.1% to about 30%, more preferably from about 0.1% to about 10% of each of the additional herbal extracts mentioned above.

Such skin diseases and / or abnormalities include skin pigmentation disease and benign and malignant skin proliferation.

Skin pigmentation disease is a disease in which the skin is typically lighter, darker, smeared or bumpy than natural. Skin pigmentation disease may exist at birth or appear in later life. Skin pigmentation disease can also be caused by sunlight. Examples of skin pigmentation diseases include, but are not limited to, aging and sun spots; freckles; Pigment loss after sun damage; freckles; And discoloration.

Cutaneous abnormalities include benign and malignant skin hyperplasia. Examples of benign and malignant skin proliferation include, but are not limited to, skin cancer or tumors such as basal cell carcinoma, squamous cell carcinoma, malignant melanoma; Actinic keratosis and sun keratosis; Skin lesions; And bumpy skin cell development. Any one of these skin abnormalities may or may not be pigmented.

While not wishing to be bound by any particular theory or hypothesis, the inventors believe that the surprising and unexpected effects exhibited by the herbal composition are generated from the synergy between the individual components. Since the additional herbal extracts mentioned above each have their own individual therapeutic action, the synergy between the individual components of the herbal composition can be further enhanced by the addition of one or more of the additional herbal extracts in the herbal composition. .

As used herein, the term “patient” refers to any animal having symptoms associated with or caused by a viral infection that requires treatment with the herbal composition. The patient can be an animal, for example a mammal, preferably a human, or a non-human primate or non-primate such as those used for animal model testing. Although the herbal composition is specifically contemplated as suitable for use in human medical treatment, the composition may also be used in veterinary treatment, such as companion animals such as dogs and cats, and domestic animals such as horses, ponies, It is also applicable to the treatment of donkeys, mules, llamas, alpacas, pigs, cows and sheep, or zoo animals such as primates, felines, canines, bovines and ungulates.

In general, the terms "treating", "treatment", etc., as used herein, mean affecting a patient, tissue, or cell to obtain the desired pharmacological and / or physiological effect. The effect may be prophylactic in connection with completely or partially preventing one or more skin diseases and / or abnormalities and / or may be therapeutic in connection with partial or complete healing of one or more skin diseases and / or abnormalities. As used herein, "treatment" includes any prophylaxis or treatment of skin diseases and / or conditions in an animal, eg, a mammal, more particularly a human,

(a) preventing one or more of the above mentioned skin diseases and / or abnormalities from occurring in a patient who is predisposed to such symptoms but has not yet seen the skin diseases and / or abnormalities;

(b) inhibit the occurrence of one or more of the aforementioned skin diseases and / or abnormalities; or

(c) alleviate, alleviate or ameliorate, ie, reverse the effects of one or more of the aforementioned skin diseases and / or conditions

It includes.

As used herein, an "effective amount" means the amount of the herbal composition for treating and / or preventing one or more of the aforementioned skin diseases and / or conditions in order to obtain the desired therapeutic response.

The term "therapeutically effective amount" means the amount of the herbal composition for obtaining the desired therapeutic response, eg for preventing and / or treating one or more of the aforementioned skin diseases and / or conditions.

The herbal composition may be administered with one or more carriers for convenience. Carriers are useful in the preparation of formulations comprising the herbal compositions, and may be administered with the compositions while allowing individual components to perform their respective functions, and are generally safe, nontoxic, biologically or otherwise undesirable. It does not contain substances. Carriers will also include those suitable for veterinary use as well as human use. Examples of carriers include dispersants, suspending agents, emulsifiers, stabilizers, wetting agents, binders, lubricants, disintegrants, solvents, media, retarders, fillers, aqueous and oily bases, non-aqueous vehicles, ie edible oils, and the like.

The herbal composition may also contain preservatives, sweeteners, colorants, flavors, thickeners and / or gelling agents, buffers and the like. Those skilled in the art will be able to identify additional additives that may be desirable, for example, for cosmetic reasons, fit, or shelf life.

As will be appreciated by those skilled in the art related to the present invention, the herbal composition may be converted to a conventional formulation. Examples of formulations include, but are not limited to, solutions, emulsions, suspensions, powders, granules, natural and synthetic substances, pills, capsules, tablets, cachets, pastilles, lozenges, tablets, softeners, pastes, containing individual components of the herbal composition. Ointments, creams, plasters, diluents, lotions, transdermal patches, enemas, suppositories, pessaries, sprays (sprays or aerosols), gargles, syrups and / or elixirs. In a preferred form of the invention, the herbal composition is converted to a formulation suitable for topical administration.

The choice of carrier and / or additives can be dictated to some extent by the intended dosage form of the herbal composition and the mode of administration of the herbal composition.

Formulations comprising such herbal compositions can be prepared by a number of standard techniques in the art, for example by mixing herbal extracts with one or more carriers and / or additives until all the ingredients are well blended. The formulations can be stored in suitable containers, bowls and the like.

Formulations suitable for oral administration are conveniently presented in discrete units, for example, in capsules, cachets or tablets each containing a predetermined amount of the herbal composition; As a powder or granules; It can be provided as a solution, a suspension or an emulsion. The herbal composition may also be provided as a ingot, soft or paste. Tablets and capsules for oral administration may contain conventional carriers such as binders, fillers, lubricants, disintegrants or wetting agents. The tablets may be coated according to methods well known in the art. Oral liquid formulations are, for example, in the form of aqueous or oily suspensions, emulsions, syrups or elixirs or as dry products, for example powders or granules, which are formulated by water or another suitable vehicle, for example orange juice, before use. Can be provided. Suitable carriers for such liquid formulations may include, for example, ethyl alcohol, vinegar, glycerin, honey, sugar or water. Such liquid formulations may also contain conventional additives such as suspending agents, emulsifying agents, non-aqueous vehicles, which may include edible oils or preservatives.

For topical administration to the skin, the herbal composition may be formulated as an ointment, cream, plaster, diluent, lotion, or as a transdermal patch. Ointments and creams may, for example, be formulated with an aqueous or oily base with the addition of suitable thickening and / or gelling agents. Examples of oily bases include, but are not limited to, vitamin E creams or lotions, glue creams, extra virgin olive oil, sweet almond oil, jojoba oil, apricot oil, peanut oil, fruit and vegetable oils, beeswax, lanolin and honey. Lotions and diluents may be formulated with an aqueous or oily base, which will generally also contain one or more emulsifiers, stabilizers, dispersants, suspending agents, thickeners or coloring agents.

Topical formulations in the form of a cream include about 40 ml of tuza extract in the form of tincture; About 80 ml of US pore extract in tincture form; About 40 ml of fragrance violet in tincture form; About 20 ml of red shamrock extract in tincture form and about 80 ml of red shamrock extract in tar form; About 10 ml of celandine extract in the form of tincture; And about 10 mL of calendula extract in leach oil form to about 200 mL of a suitable cream base (approximately about 40%). The components can be blended by mixing, stirring and / or heating, as known in the art. The cream based topical formulation can then be dispensed into a container suitable for use.

Formulations suitable for topical administration to the oral cavity include lozenges comprising the herbal composition, including flavor bases such as sucrose and gum arabic or tragacanth; Pastilles comprising the herbal composition in an inert base such as gelatin or sucrose and gum arabic; And dentifrice in a suitable liquid carrier.

In use, the herbal composition will be administered to a patient in need, purpose, or as advised by a medical practitioner, pharmacist, physician, medical herbalist, naturopath or veterinarian. The selection of the herbal extracts may also be carried out according to the specific needs of the patient.

As will be appreciated, the dose administered, duration of administration, and general dosing regimen may include the patient's resistance to some active ingredients, weight, metabolism, route of administration chosen, severity of symptoms, and age and / or general health of the patient. It can vary from patient to patient depending on the variable. In general, when converting the herbal composition into a formulation suitable for topical administration, a dosage regimen common to the topical treatment is applied to the affected area about 3 times a day. Topical treatments may also be supplemented by oral administration.

Treatment is preferably initiated before or when the skin disease and / or abnormalities appear, and is continued until the skin disease and / or abnormalities no longer exist.

The invention will now be further described with reference to the following non-limiting examples.

Example

Patient A

Personal Content:

A woman in her late forties with a fat white blond hair. She was too exposed to daylight in adolescence and early adulthood.

Status (s):

Aging spots appeared on the back of the hand, forearm and forehead. Some of the aging spots were itchy and scaly.

Recommended Orthodox Treatment:

Removal by cauterization.

Patient B

Personal Content:

A woman in her late sixties, very fat. She was very active in her outdoor life and was exposed to too much sunlight, making her skin burned properly.

Status (s):

There has been a sharp increase in sun-induced skin abnormalities including basal cell carcinoma as well as rays and sun keratosis and sun spots.

Recommended Orthodox Treatment:

Removal by cauterization.

Patient C

Personal Content:

Flirty white mid 70s woman. She lived a very active outdoor life.

Status (s):

There has been a sharp increase in sun-induced skin abnormalities including basal cell carcinoma as well as rays and sun keratosis and sun spots.

Recommended Orthodox Treatment:

Removal by cauterization.

Patient D

Personal Content:

Fat white man in mid 80s.

Status (s):

Melanoma appeared in the nose.

Recommended Orthodox Treatment:

Surgical Resection (Cutting).

Patient E

Personal Content:

Blond early forties women with olive skin. She lived a very active outdoor life.

Status (s):

Sun spots appeared on the face.

Recommended Orthodox Treatment:

Did not find orthodox treatment.

Patient F

Personal Content:

Fat white man in his late sixties. He lived in the open air.

Status (s):

Sun spots and actinic keratosis were present.

Recommended Orthodox Treatment:

Surgical excision is recommended because of the rapid change in nasal keratosis.

Patient G

Personal Content:

Men in their mid 50s with very white skin. He spent most of his adult life working outdoors.

Status (s):

There is a 12-year history of basal cell carcinoma and two squamous cell carcinomas.

Recommended Orthodox Treatment:

Surgical excision (cutting), ablation (resistance) removal and / or use of corrosive (erosive) creams.

cure

Each patient was treated with a herbal composition according to the invention.

The herbal composition was prepared as a topical formulation in the form of a cream by mixing the following ingredients:

About 40 ml of tuza extract in tincture form;

About 80 ml of US pore extract in tincture form;

About 40 ml of fragrance violet extract in the form of a tincture;

About 20 ml of red shamrock extract in tincture form and about 80 ml of red shamrock extract in tar form;

About 10 ml of celandine extract in the form of tincture;

About 10 ml of calendula extract in leach oil form; And

About 200 ml of a glucated cream base containing sweet almond oil, glucose and water.

Each patient was prescribed to apply the cream at least three times daily to the affected area.

result

Patient A applied the cream for a period of 3 months as prescribed. At the end of this period, all signs of aging spots disappeared, leaving normal and healthy skin, ie no scars.

Patient B applied the cream as prescribed. Skin abnormalities and sun spots disappeared, leaving normal and healthy skin, ie no scars. There were no signs of any new skin abnormalities.

Patient C applied the cream as prescribed. Skin abnormalities and sun spots disappeared, leaving normal and healthy skin instead, ie no scars. The cream was used for a period of time to prevent new sun spots from appearing.

Patient D applied the cream as prescribed for a period of two weeks. After this time, the melanoma decreased and disappeared, leaving a normal and healthy skin instead, ie no scars. No recurrence of melanoma has been reported.

Patient E applied the cream as prescribed. After a period of one month, sun spots disappeared, leaving normal and healthy skin, ie no scars.

Patient F applied the cream as prescribed and within 1 month of treatment the sun spots and actinic keratosis disappeared, leaving normal and healthy skin, ie no scars.

Patient G applied the cream as prescribed. Skin abnormalities disappeared in a short time.

In the above description, reference is made to certain components or wholes of the invention that are known to be equivalent, such equivalents being cited in the invention as described separately.

While the present invention has been disclosed by way of examples and with reference to possible embodiments thereof, it is, of course, possible to make changes or improvements to the invention without departing from the scope of the invention.

Claims (46)

Tuja (tuja oxydentalis); American Zigong (Pittoraca decandra); Fragrance violets (viola odorata); Red shamrock (tripoleum pratense); Celandine (Kellydonium Mazu); And Calendula (Calendula Offisinalis) Herbal composition comprising an extract from. The herbal composition of claim 1 comprising from about 0.5 to about 20% of a tuza extract. The herbal composition of claim 1 or claim 2 comprising about 1 to about 20% of the US periwinkle extract. 4. A herbal composition according to any one of claims 1 to 3, comprising from about 0.5 to about 12% fragrance violet extract. The method according to any one of claims 1 to 4, wherein when the red shamrock extract is in the form of tar, about 1 to about 30% of the red shamrock extract, and / or the red shamrock extract is in the form of a tincture agent. If desired, comprising about 0.5 to about 20% of said red shamrock extract. 6. The herbal composition according to any one of claims 1 to 5, comprising from about 0.2 to about 10% celandine extract. 7. The herbal composition according to any one of claims 1 to 6, comprising about 1 to about 16% calendula extract. 8. The herbal composition according to any one of claims 1 to 7, which comprises about 6 to about 10% tusa extract. 9. A herbal composition according to any one of claims 1 to 8, comprising about 14 to about 18% of the US pore extract. 10. The herbal composition according to any one of claims 1 to 9, comprising about 6 to about 10% fragrance violet extract. The method according to claim 1, wherein when the red shamrock extract is in the form of tar, about 14 to about 18% of the red shamrock extract, and / or the red shamrock extract is in the form of a tincture agent. If desired, comprising about 2 to about 6% of said red shamrock extract. 12. The herbal composition according to any one of claims 1 to 11, comprising from about 3 to about 4% celandine extract. 13. The herbal composition according to any one of claims 1 to 12, comprising about 6 to about 10% calendula extract. 14. The herbal composition according to any one of claims 1 to 13, comprising about 8% tusa extract. 15. The herbal composition according to any one of claims 1 to 14, comprising about 16% of the US periwinkle extract. 16. The herbal composition according to any one of claims 1 to 15, comprising about 8% fragrance violet extract. The method of claim 1, wherein when the red shamrock extract is in the form of tar, about 16% of the red shamrock extract, and / or the red shamrock extract is in the form of a tincture agent, Herb composition comprising 4% of the red shamrock extract. 18. The herbal composition according to any one of claims 1 to 17, comprising about 2% celandine extract. 19. The herbal composition according to any one of claims 1 to 18, comprising about 8% calendula extract. The method according to any one of claims 1 to 19, irises, rakes, golden seals, sasafras, yellow dogs, echinacea, myrrh, pasqueflower, aloe, garlic, American algae, hyunsam, nettle, pylon A herbal composition also comprising an extract of at least one of Hypericum, Corydalis, Slippery Elm, Blood Root, Burdock, Ginger and St. Mary's Thistle. 21. The method according to any one of claims 1 to 20, comprising from about 0.1% to about 30% of irises, rakes, golden seals, sasapras, yellow dogs, echinacea, myrrh, pasqueflower, aloe, garlic, Herbal composition comprising extracts of one or more of American Crabweed, Hyunsam, Nettle, Pilewort, Hypericum, Corydalis, Slippery Elm, Blood Root, Burdock, Ginger and St. Mary's Thistle. 22. The method according to any one of claims 1 to 21, comprising from about 0.1% to about 10% of irises, rakes, golden seals, sasafras, yellow dogs, echinacea, myrrh, pasqueflower, aloe, garlic, Herbal composition comprising extracts of one or more of American Crabweed, Hyunsam, Nettle, Pilewort, Hypericum, Corydalis, Slippery Elm, Blood Root, Burdock, Ginger and St. Mary's Thistle. 23. The herbal composition according to any one of claims 1 to 22, wherein the extract is in the form of tinctures, fluid extracts or solid extracts, tars, leach oils or mixtures thereof. 24. The extract according to any one of claims 1 to 23, wherein the tuja extract is in the form of a tincture agent, the US periwinkle extract is in the form of a tincture agent, the fragrance violet extract is in the form of a tincture agent, and the red shamrock extract is formed of tar. The herbaceous composition is in the form of a celandine extract is in the form of tincture, calendula extract in oil or in the form of tincture. 25. The herbal composition according to any one of claims 1 to 24, further comprising a red shamrock extract in the form of a tincture. 26. A herbal formulation comprising a herbal composition according to any one of claims 1 to 25 together with one or more carriers. 27. A herbal formulation according to claim 26 in the form of a topical formulation. The herbal formulation according to claim 27, wherein the topical formulation is a cream. 27. A herbal formulation according to claim 26 in the form of an oral formulation. 30. The herbal formulation of claim 29, wherein the oral formulation is a solution. A therapeutically effective amount of a herbal composition according to any one of claims 1 to 25 or a herbal formulation according to any one of claims 26 to 30 for a patient in need of preventing and / or treating skin diseases and / or conditions. Administering to said method of preventing and / or treating. 32. The method of claim 31, wherein the skin disease is a skin pigmentation disease. 33. The method of claim 32, wherein the skin pigmentation disorder is selected from the group consisting of aging or sun spots; freckles; Pigment loss after sun damage; freckles; Or discoloration method. 32. The method of claim 31, wherein the skin abnormality is benign or malignant skin proliferation. The method of claim 34, wherein the benign or malignant skin proliferation is selected from the group consisting of skin cancer or a tumor; Actinic keratosis; Solar keratosis; Skin lesions; Or bumpy skin cell development. 36. The method of claim 35, wherein the skin cancer or tumor is basal cell carcinoma; Squamous cell carcinoma; Or malignant melanoma. 37. The method of claim 35 or 36, wherein the benign or malignant skin proliferation is colored or uncolored. 38. The method of any one of claims 31-37, wherein the patient is an animal, mammal or human. 39. The method of any one of claims 31-38, wherein the herbal composition or herbal formulation is in the form of a topical formulation. The method of claim 39, wherein the topical formulation is in the form of a cream. 41. The method of claim 40, wherein the cream is applied about three times a day. 42. The method of any one of claims 31 to 41, wherein the herbal composition or herbal formulation is administered topically and / or orally. 26. A herbal composition according to any one of claims 1 to 25 or a herbal according to any one of claims 26 to 30 for the manufacture of a medicament for the prophylaxis and / or treatment of skin diseases and / or conditions. Use of the formulation. Use of the herbal composition according to any one of claims 1 to 25 or the herbal formulation according to any one of claims 26 to 30 for the prevention and / or treatment of skin diseases and / or conditions. 26. A herbal composition according to any one of claims 1 to 25 or a herbal formulation according to any one of claims 26 to 30 for use in the prophylaxis and / or treatment of skin diseases and / or conditions. An agent comprising the herbal composition according to any one of claims 1 to 25 or the herbal formulation according to any one of claims 26 to 30 for the prevention and / or treatment of skin diseases and / or conditions. .