KR20070038509A - 레티노산의 아미노, 아미노산 또는 펩타이드 결합체 - Google Patents

레티노산의 아미노, 아미노산 또는 펩타이드 결합체 Download PDF

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Publication number
KR20070038509A
KR20070038509A KR1020077000471A KR20077000471A KR20070038509A KR 20070038509 A KR20070038509 A KR 20070038509A KR 1020077000471 A KR1020077000471 A KR 1020077000471A KR 20077000471 A KR20077000471 A KR 20077000471A KR 20070038509 A KR20070038509 A KR 20070038509A
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KR
South Korea
Prior art keywords
residue
alkyl
peptide
residues
pag
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Ceased
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KR1020077000471A
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English (en)
Korean (ko)
Inventor
라파엘 뷰머
조켄 클록
주어겐 에이치 볼하르트
필립 엠마뉴엘 마일란
스테판 스톡클리
Original Assignee
디에스엠 아이피 어셋츠 비.브이.
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Publication of KR20070038509A publication Critical patent/KR20070038509A/ko
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Birds (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Pyrrole Compounds (AREA)
KR1020077000471A 2004-07-09 2005-07-01 레티노산의 아미노, 아미노산 또는 펩타이드 결합체 Ceased KR20070038509A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04016239.8 2004-07-09
EP04016239 2004-07-09

Publications (1)

Publication Number Publication Date
KR20070038509A true KR20070038509A (ko) 2007-04-10

Family

ID=35062952

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077000471A Ceased KR20070038509A (ko) 2004-07-09 2005-07-01 레티노산의 아미노, 아미노산 또는 펩타이드 결합체

Country Status (7)

Country Link
US (1) US20070270472A1 (https=)
EP (1) EP1765773A2 (https=)
JP (1) JP2008515770A (https=)
KR (1) KR20070038509A (https=)
CN (1) CN101048375B (https=)
BR (1) BRPI0513145A (https=)
WO (1) WO2006005455A2 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101224809B1 (ko) * 2012-04-24 2013-01-21 주식회사 아이피어리스 레티노산 유도체, 이의 제조 방법 및 이를 포함하는 화장품 조성물
KR20180124411A (ko) * 2017-05-11 2018-11-21 (주)케어젠 이소트레티노인과 펩타이드의 결합체
KR20200009380A (ko) * 2018-07-18 2020-01-30 주식회사 코리아나화장품 초유 및 오르니틴을 유효성분으로 함유하는 피부 주름 개선용 화장료 조성물
KR20210092483A (ko) 2020-01-16 2021-07-26 맹창남 모발 및 두피상태 개선용 화장료 조성물
KR20250136628A (ko) 2024-03-08 2025-09-16 주식회사 에이치엔컴퍼니 모발 개선용 화장료 조성물

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WO2007079394A2 (en) * 2005-12-30 2007-07-12 Revance Therapeutics, Inc. Arginine heteromers for topical administration
WO2009051213A1 (ja) * 2007-10-19 2009-04-23 The University Of Tokyo 白斑治療剤および色素沈着促進方法
TWI550063B (zh) * 2009-09-29 2016-09-21 Shiseido Co Ltd Antioxidant composition
JP5864615B2 (ja) * 2011-01-25 2016-02-17 ザ プロクター アンド ギャンブルカンパニー リポソーム及びそれを含むパーソナルケア組成物
EP2745904B1 (en) 2012-12-21 2015-12-16 Dionex Corporation HILIC/Anion-Exchange/Cation-Exchange Multimodal Media
US9511144B2 (en) 2013-03-14 2016-12-06 The Proctor & Gamble Company Cosmetic compositions and methods providing enhanced penetration of skin care actives
WO2015023926A1 (en) * 2013-08-15 2015-02-19 Mary Kay Inc. Topical skin compositions for treating wrinkles
FR3054130B1 (fr) * 2016-07-22 2019-04-26 Syntivia Procede de traitement cosmetique de la peau
US11148998B2 (en) 2017-05-23 2021-10-19 The Regents Of The University Of Michigan Dimethyl-nonatetraenyl-trimethyl-cyclohexyl compounds and uses thereof
CN110785161B (zh) 2017-06-23 2023-06-20 宝洁公司 用于改善皮肤外观的组合物和方法
CN112437657A (zh) 2018-07-03 2021-03-02 宝洁公司 处理皮肤状况的方法
US10959933B1 (en) 2020-06-01 2021-03-30 The Procter & Gamble Company Low pH skin care composition and methods of using the same
JP7590462B2 (ja) 2020-06-01 2024-11-26 ザ プロクター アンド ギャンブル カンパニー ビタミンｂ３化合物の皮膚への浸透を改善する方法
CN117384073A (zh) * 2022-07-11 2024-01-12 南京毓浠医药技术有限公司 一种维a酸醇胺类复合物及其制备方法和应用
CN118121574A (zh) * 2022-12-02 2024-06-04 南京毓浠医药技术有限公司 一种含维a酸组合物及其制备方法和用途
CN118126119B (zh) * 2024-05-10 2024-08-06 荷本世新(北京)生物科技有限公司 维a酸多肽衍生物及其制备方法和用途
CN121517355A (zh) * 2026-01-15 2026-02-13 珀莱雅化妆品股份有限公司 一种吡哆胺衍生物、制备方法及其应用

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CH529742A (de) * 1970-02-02 1972-10-31 Hoffmann La Roche Verfahren zur Herstellung von Vitamin-A-Säureamiden
US3950418A (en) * 1970-02-02 1976-04-13 Hoffmann-La Roche Inc. Vitamin A acid amides
DE2300107C2 (de) * 1973-01-03 1982-03-11 Basf Ag, 6700 Ludwigshafen Vitamin A-Säureanilid-4-carbonsäureäthylester, Verfahren zu seiner Herstellung und diesen enthaltende Zubereitungen
US4108880A (en) * 1975-11-03 1978-08-22 Johnson & Johnson Esters of retinoic acid
CH661516A5 (de) * 1983-12-08 1987-07-31 Hoffmann La Roche Phenylnonatetraenoylzuckerderivate.
US5559149A (en) * 1990-01-29 1996-09-24 Johnson & Johnson Consumer Products, Inc. Skin care compositions containing retinoids
DE4032187C2 (de) * 1990-10-10 1995-03-30 Gradinger F Hermes Pharma N-Retinoyl-L-aminomercapto-Verbindungen und Zwischenprodukte, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19523079A1 (de) * 1995-06-26 1997-01-02 Basf Ag Ester und Amide der 9(Z)-Retinsäure
KR100297061B1 (ko) * 1998-03-30 2001-09-22 성재갑 폴리에톡실화 레틴아미드 유도체 및 그의 제조방법
US6692754B1 (en) * 1999-03-02 2004-02-17 Kyowa Hakko Kogyo Co., Ltd. Cosmetic composition
JP2001039997A (ja) * 1999-07-29 2001-02-13 Lion Corp 安定化されたレチノイン酸類の誘導体、ならびにそれらを含有する外用剤組成物
JP4221547B2 (ja) * 2001-01-26 2009-02-12 ライオン株式会社 レチノイン酸類またはその誘導体を含有する組成物
KR100439627B1 (ko) * 2001-06-18 2004-07-12 주식회사 엘지생활건강 피부주름 예방 및 치료용 조성물
US20050239749A1 (en) * 2002-07-25 2005-10-27 Lion Corporation External preparation
CN1197847C (zh) * 2002-09-02 2005-04-20 复旦大学 化合物n－全反式维甲酰胺衍生物及其制备方法和应用
JP4256389B2 (ja) * 2003-11-17 2009-04-22 セダーマ テトラペプチドとトリペプチドの混合物を含む組成物

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101224809B1 (ko) * 2012-04-24 2013-01-21 주식회사 아이피어리스 레티노산 유도체, 이의 제조 방법 및 이를 포함하는 화장품 조성물
KR20180124411A (ko) * 2017-05-11 2018-11-21 (주)케어젠 이소트레티노인과 펩타이드의 결합체
WO2018208124A3 (ko) * 2017-05-11 2019-03-28 (주)케어젠 이소트레티노인과 펩타이드의 결합체
AU2018264739B2 (en) * 2017-05-11 2020-08-27 Caregen Co., Ltd. Conjugate of isotretinoin and peptide
US11351266B2 (en) 2017-05-11 2022-06-07 Caregen Co., Ltd. Conjugate of isotretinoin and peptide
US12005123B2 (en) 2017-05-11 2024-06-11 Caregen Co., Ltd. Conjugate of isotretinoin and peptide
KR20200009380A (ko) * 2018-07-18 2020-01-30 주식회사 코리아나화장품 초유 및 오르니틴을 유효성분으로 함유하는 피부 주름 개선용 화장료 조성물
KR20210092483A (ko) 2020-01-16 2021-07-26 맹창남 모발 및 두피상태 개선용 화장료 조성물
KR20250136628A (ko) 2024-03-08 2025-09-16 주식회사 에이치엔컴퍼니 모발 개선용 화장료 조성물

Also Published As

Publication number Publication date
CN101048375A (zh) 2007-10-03
CN101048375B (zh) 2012-12-05
US20070270472A1 (en) 2007-11-22
EP1765773A2 (en) 2007-03-28
WO2006005455A2 (en) 2006-01-19
JP2008515770A (ja) 2008-05-15
BRPI0513145A (pt) 2008-04-29
WO2006005455A3 (en) 2008-02-07

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