KR20060064620A - 개선된 글루코스 데히드로게나제 폴리펩티드 및 관련폴리뉴클레오티드 - Google Patents

개선된 글루코스 데히드로게나제 폴리펩티드 및 관련폴리뉴클레오티드 Download PDF

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KR20060064620A
KR20060064620A KR1020067002919A KR20067002919A KR20060064620A KR 20060064620 A KR20060064620 A KR 20060064620A KR 1020067002919 A KR1020067002919 A KR 1020067002919A KR 20067002919 A KR20067002919 A KR 20067002919A KR 20060064620 A KR20060064620 A KR 20060064620A
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gly
val
lys
glu
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앵크 크레버
리사 마리 뉴먼
에스 크리스토퍼 데이비스
스테판 제이 젠느
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코덱시스, 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)

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  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
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  • Biotechnology (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020067002919A 2003-08-11 2004-08-11 개선된 글루코스 데히드로게나제 폴리펩티드 및 관련폴리뉴클레오티드 Ceased KR20060064620A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49430003P 2003-08-11 2003-08-11
US60/494,300 2003-08-11
US54565704P 2004-02-18 2004-02-18
US60/545,657 2004-02-18

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KR20060064620A true KR20060064620A (ko) 2006-06-13

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KR1020067002919A Ceased KR20060064620A (ko) 2003-08-11 2004-08-11 개선된 글루코스 데히드로게나제 폴리펩티드 및 관련폴리뉴클레오티드

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Country Link
US (2) US7816111B2 (https=)
EP (1) EP1660648B1 (https=)
JP (1) JP2007502114A (https=)
KR (1) KR20060064620A (https=)
AU (1) AU2004288134B2 (https=)
BR (1) BRPI0413492A (https=)
CA (1) CA2535147A1 (https=)
IL (1) IL173260A0 (https=)
MX (1) MXPA06001719A (https=)
NO (1) NO20060543L (https=)
WO (1) WO2005045016A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
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KR20140032393A (ko) * 2011-03-30 2014-03-14 유니티카 가부시끼가이샤 개변형 글루코스 데히드로게나제

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EP2365073A1 (en) 2005-03-25 2011-09-14 Ikeda Food Research Co. Ltd. Coenzyme-linked glucose dehydrogenase and polynucleotide encoding the same
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WO2008042876A2 (en) 2006-10-02 2008-04-10 Codexis, Inc. Compositions and methods for producing stereoisomerically pure statins and synthetic intermediates therefor
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CN106232619B (zh) 2013-11-13 2022-09-09 科德克希思公司 工程化的亚胺还原酶和用于酮和胺化合物的还原胺化的方法
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WO2016130412A1 (en) 2015-02-10 2016-08-18 Codexis, Inc. Ketoreductase polypeptides for the synthesis of chiral compounds
CA3035874C (en) 2016-10-05 2025-09-09 F. Hoffmann-La Roche Ag DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTICAL DIAGNOSTIC TEST ELEMENTS, AS WELL AS THEIR METHODS OF USE
EP3339431A1 (en) * 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Glucose dehydrogenase variants with improved properties
JP2021506252A (ja) * 2017-12-13 2021-02-22 コデクシス， インコーポレイテッド アミドカップリングのためのカルボキシエステラーゼポリペプチド
ES2975412T3 (es) 2018-06-21 2024-07-05 Fis Fabbrica Italiana Sintetici Spa Proceso enzimático para la preparación de droxidopa
JP6480629B1 (ja) * 2018-08-07 2019-03-13 キッコーマン株式会社 グルコースデヒドロゲナーゼの組換え製造方法
WO2020123563A1 (en) * 2018-12-10 2020-06-18 The Regents Of The University Of California Engineered polypeptides that exhibit increased catalytic efficiency for unnatural cofactors and uses thereof
CN114096662B (zh) * 2019-05-01 2025-04-15 科德克希思公司 工程化葡萄糖脱氢酶和用于酮和胺化合物的还原胺化的方法
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140032393A (ko) * 2011-03-30 2014-03-14 유니티카 가부시끼가이샤 개변형 글루코스 데히드로게나제

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WO2005045016A3 (en) 2005-11-10
US20100304459A1 (en) 2010-12-02
NO20060543L (no) 2006-03-13
JP2007502114A (ja) 2007-02-08
CA2535147A1 (en) 2005-05-19
US7939309B2 (en) 2011-05-10
US7816111B2 (en) 2010-10-19
US20050095619A1 (en) 2005-05-05
MXPA06001719A (es) 2006-05-19
EP1660648B1 (en) 2013-10-09
WO2005045016A2 (en) 2005-05-19
AU2004288134A1 (en) 2005-05-19
EP1660648A2 (en) 2006-05-31
BRPI0413492A (pt) 2006-10-17
AU2004288134B2 (en) 2009-12-17
IL173260A0 (en) 2006-06-11

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