KR20050103221A - 개선된 방사성금속 착물 조성물 - Google Patents

개선된 방사성금속 착물 조성물 Download PDF

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Publication number
KR20050103221A
KR20050103221A KR1020057014518A KR20057014518A KR20050103221A KR 20050103221 A KR20050103221 A KR 20050103221A KR 1020057014518 A KR1020057014518 A KR 1020057014518A KR 20057014518 A KR20057014518 A KR 20057014518A KR 20050103221 A KR20050103221 A KR 20050103221A
Authority
KR
South Korea
Prior art keywords
formula
biocompatible
conjugate
radiopharmaceutical
stabilized composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020057014518A
Other languages
English (en)
Korean (ko)
Inventor
데이비드 맥길
잉그리드 헨리크센
Original Assignee
지이 헬쓰케어 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 지이 헬쓰케어 리미티드 filed Critical 지이 헬쓰케어 리미티드
Publication of KR20050103221A publication Critical patent/KR20050103221A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020057014518A 2003-02-07 2004-02-09 개선된 방사성금속 착물 조성물 Withdrawn KR20050103221A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03002809A EP1444990A1 (en) 2003-02-07 2003-02-07 Improved Radiometal Complex Compositions
EP03002809.6 2003-02-07

Publications (1)

Publication Number Publication Date
KR20050103221A true KR20050103221A (ko) 2005-10-27

Family

ID=32605351

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057014518A Withdrawn KR20050103221A (ko) 2003-02-07 2004-02-09 개선된 방사성금속 착물 조성물

Country Status (16)

Country Link
US (1) US20070020177A1 (https=)
EP (2) EP1444990A1 (https=)
JP (2) JP2006528205A (https=)
KR (1) KR20050103221A (https=)
CN (1) CN100548387C (https=)
AT (1) ATE487498T1 (https=)
AU (1) AU2004210191B2 (https=)
BR (1) BRPI0407056A (https=)
CA (1) CA2514307A1 (https=)
DE (1) DE602004029983D1 (https=)
ES (1) ES2355100T3 (https=)
MX (1) MXPA05008356A (https=)
NO (1) NO20053754L (https=)
RU (1) RU2005123799A (https=)
WO (1) WO2004069285A1 (https=)
ZA (1) ZA200506728B (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1444990A1 (en) * 2003-02-07 2004-08-11 Amersham plc Improved Radiometal Complex Compositions
US8741261B2 (en) * 2003-12-18 2014-06-03 Ge Healthcare Limited Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via isocyanate using azides and carbon-isotope monoxide
US7667011B2 (en) 2004-12-03 2010-02-23 Bengt Langstrom Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled acids by photo-induced free radical carbonylation
GB0428020D0 (en) 2004-12-22 2005-01-26 Amersham Health As Stabilisation of radiopharmaceutical precursors
ES2386364T3 (es) * 2005-02-01 2012-08-17 Ge Healthcare Limited Procedimiento de uso de monóxido de carbono [11C] en la síntesis de marcado de compuestos marcados por 11C por carbonilación de radical libre inducida térmicamente
US20060217537A1 (en) * 2005-03-22 2006-09-28 Bengt Langstrom Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via ketene using diazo compounds and carbon-isotope monoxide
CA2610252A1 (en) * 2005-06-14 2006-12-21 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic imaging agent
US8273861B2 (en) 2005-08-31 2012-09-25 Ge Healthcare Limited Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled ketones by photo-induced free radical carbonylation
WO2008056481A1 (en) * 2006-11-09 2008-05-15 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic imaging agent
RU2366434C1 (ru) * 2007-12-07 2009-09-10 Институт неорганической химии им. А.В. Николаева Сибирского отделения Российской Академии наук Гексаядерные кластерные комплексы рения на основе радиоактивных изотопов, обладающие противоопухолевыми свойствами
GB0922023D0 (en) * 2009-12-17 2010-02-03 Ge Healthcare Ltd Preparation of n-monofluoroalkyl compounds
US9951324B2 (en) 2010-02-25 2018-04-24 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
EP2598175B1 (en) 2010-07-27 2020-05-20 Serac Healthcare Limited Radiopharmaceutical compositions
BR112015011118B1 (pt) * 2012-11-15 2022-12-13 Endocyte, Inc Conjugado; composição farmacêutica; e uso de um conjugado
JP2016510342A (ja) * 2013-02-15 2016-04-07 トーマス・ジェファーソン・ユニバーシティＴｈｏｍａｓ Ｊｅｆｆｅｒｓｏｎ Ｕｎｉｖｅｒｓｉｔｙ 腫瘍画像化のためのキット
LT4095130T (lt) 2013-10-18 2024-04-25 Novartis Ag Žymėti prostatos specifinio membranos antigeno (psma) inhibitoriai, jų naudojimas kaip vizualizavimo medžiagų ir farmacinių medžiagų prostatos vėžiui gydyti
BR112016010927A2 (pt) 2013-11-14 2017-08-08 Endocyte Inc Conjugado de fórmula
US20150375901A1 (en) * 2014-06-30 2015-12-31 Karen J. Orlich Reusable, eco-friendly container for storing and dispensing food and beverage
US10188759B2 (en) 2015-01-07 2019-01-29 Endocyte, Inc. Conjugates for imaging
RU2624237C1 (ru) * 2016-10-26 2017-07-03 Федеральное государственное бюджетное учреждение "Государственный научный центр Российской Федерации - Федеральный медицинский биофизический центр имени А.И. Бурназяна" Радиофармацевтическая композиция для радиосиновэктомии и способ ее получения
US10478824B2 (en) 2017-08-21 2019-11-19 Bliss Industries, Llc System and method for installing hammers
US10207274B1 (en) 2017-08-21 2019-02-19 Roger Young Non-forged hammermill hammer
US12138630B2 (en) 2017-08-21 2024-11-12 Bliss Industries, Llc Hammermill hammer
USD905136S1 (en) 2018-03-05 2020-12-15 Bliss Industries, Llc Hammermill hammer
US10610870B2 (en) 2017-08-21 2020-04-07 Bliss Industries, Llc Hot and cold forming hammer and method of assembly
US10486160B2 (en) 2017-08-21 2019-11-26 Bliss Industries, Llc Method of replacing hammers and spacers
USD839934S1 (en) 2017-12-06 2019-02-05 Roger Young Swing hammer
USD861048S1 (en) 2017-12-06 2019-09-24 Roger Young Swing hammer
USD840447S1 (en) 2017-12-06 2019-02-12 Roger Young Swing hammer
US12208102B2 (en) 2018-04-17 2025-01-28 Endocyte, Inc. Methods of treating cancer
CN114096264B (zh) 2019-05-20 2025-03-14 因多塞特股份有限公司 制备psma缀合物的方法
WO2022156908A1 (en) * 2021-01-25 2022-07-28 Vrije Universiteit Brussel Method for preparing a lyophilized composition

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364920A (en) * 1975-04-30 1982-12-21 Medi-Physics, Inc. Stable diagnostic reagents
US4233284A (en) * 1978-03-31 1980-11-11 The Procter & Gamble Company Stabilized radiographic scanning agents
US4497744A (en) * 1978-03-31 1985-02-05 Mallinckrodt, Inc. Gentisic acid salts as radiographic scanning agent stabilizers
DE78642T1 (de) * 1981-10-30 1983-10-27 Amersham International Plc, Amersham, Buckinghamshire Radiopharmazeutische zubereitung auf grund von technetium-99m und reagenz zur herstellung derselben.
US6241963B1 (en) * 1995-10-19 2001-06-05 The Trustees Of The University Of Pennsylvania Dopamine and serotonin transporter ligands and imaging agents
US7105678B2 (en) * 1995-11-03 2006-09-12 Organix, Inc. Boat tropanes
US6171576B1 (en) 1995-11-03 2001-01-09 Organix Inc. Dopamine transporter imaging agent
US5961955A (en) * 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope
US20020111486A1 (en) * 1999-12-03 2002-08-15 Tamagnan Gilles Denis Transition metal-cyclopentadienyl-tropane conjugates
GB0031592D0 (en) * 2000-12-28 2001-02-07 Nycomed Amersham Plc Stabilised radiopharmaceutical compositions
FR2833952B1 (fr) 2001-12-26 2004-03-26 Schering Ag Derive du tropane, produit de chelation comprenant ce derive de tropane et un metal ou un complexe de metal et radiopharmaceutique
EP1444990A1 (en) * 2003-02-07 2004-08-11 Amersham plc Improved Radiometal Complex Compositions

Also Published As

Publication number Publication date
RU2005123799A (ru) 2006-03-27
WO2004069285A1 (en) 2004-08-19
US20070020177A1 (en) 2007-01-25
JP2011132258A (ja) 2011-07-07
BRPI0407056A (pt) 2006-01-17
ATE487498T1 (de) 2010-11-15
JP2006528205A (ja) 2006-12-14
EP1590007B1 (en) 2010-11-10
NO20053754D0 (no) 2005-08-05
EP1444990A1 (en) 2004-08-11
MXPA05008356A (es) 2006-03-13
AU2004210191B2 (en) 2007-08-23
ZA200506728B (en) 2006-10-25
CN100548387C (zh) 2009-10-14
CA2514307A1 (en) 2004-08-19
CN1767859A (zh) 2006-05-03
DE602004029983D1 (de) 2010-12-23
NO20053754L (no) 2005-10-05
AU2004210191A1 (en) 2004-08-19
ES2355100T3 (es) 2011-03-22
EP1590007A1 (en) 2005-11-02

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20050805

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid