BRPI0407056A - Composição estabilizada, e precursora, composto radiofarmacêutico, kit e método para a preparação do mesmo, uso do composto radiofarmacêutico, e, método de formação de imagem diagnóstica do corpo de mamìfero - Google Patents

Composição estabilizada, e precursora, composto radiofarmacêutico, kit e método para a preparação do mesmo, uso do composto radiofarmacêutico, e, método de formação de imagem diagnóstica do corpo de mamìfero

Info

Publication number
BRPI0407056A
BRPI0407056A BR0407056-9A BRPI0407056A BRPI0407056A BR PI0407056 A BRPI0407056 A BR PI0407056A BR PI0407056 A BRPI0407056 A BR PI0407056A BR PI0407056 A BRPI0407056 A BR PI0407056A
Authority
BR
Brazil
Prior art keywords
radiopharmaceutical compound
preparation
kit
precursor composition
diagnostic imaging
Prior art date
Application number
BR0407056-9A
Other languages
English (en)
Inventor
David Mcgill
Ingrid Henriksen
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of BRPI0407056A publication Critical patent/BRPI0407056A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"COMPOSIçãO ESTABILIZADA, E PERCURSORA, COMPOSTO RADIOFARMACêUTICO, KIT E MéTODO PARA A PREPARAçãO DO MESMO, USO DO COMPOSTO RADIOFARMACêUTICO, E, MéTODO DE FORMAçãO DE IMAGEM DIAGNóSTICA DO CORPO DE MAMìFERO" A presente invenção refere-se a composições de complexo metálicas de tecnécio e rênio, estabilizadas, compreendendo um radioprotetor e um complexo de radiometal de um conjugado de agente quelante tetradentado-tropano, em que o complexo de radiometal é neutro. São também descritos compostos radiofarmacêuticos, compreendendo as composições de complexo metálicas estabilizadas, e kits para a preparação dos compostos radiofarmacêuticos
BR0407056-9A 2003-02-07 2004-02-09 Composição estabilizada, e precursora, composto radiofarmacêutico, kit e método para a preparação do mesmo, uso do composto radiofarmacêutico, e, método de formação de imagem diagnóstica do corpo de mamìfero BRPI0407056A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03002809A EP1444990A1 (en) 2003-02-07 2003-02-07 Improved Radiometal Complex Compositions
PCT/GB2004/000443 WO2004069285A1 (en) 2003-02-07 2004-02-09 Improved radiometal complex compositions

Publications (1)

Publication Number Publication Date
BRPI0407056A true BRPI0407056A (pt) 2006-01-17

Family

ID=32605351

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0407056-9A BRPI0407056A (pt) 2003-02-07 2004-02-09 Composição estabilizada, e precursora, composto radiofarmacêutico, kit e método para a preparação do mesmo, uso do composto radiofarmacêutico, e, método de formação de imagem diagnóstica do corpo de mamìfero

Country Status (16)

Country Link
US (1) US20070020177A1 (pt)
EP (2) EP1444990A1 (pt)
JP (2) JP2006528205A (pt)
KR (1) KR20050103221A (pt)
CN (1) CN100548387C (pt)
AT (1) ATE487498T1 (pt)
AU (1) AU2004210191B2 (pt)
BR (1) BRPI0407056A (pt)
CA (1) CA2514307A1 (pt)
DE (1) DE602004029983D1 (pt)
ES (1) ES2355100T3 (pt)
MX (1) MXPA05008356A (pt)
NO (1) NO20053754L (pt)
RU (1) RU2005123799A (pt)
WO (1) WO2004069285A1 (pt)
ZA (1) ZA200506728B (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1444990A1 (en) * 2003-02-07 2004-08-11 Amersham plc Improved Radiometal Complex Compositions
US8741261B2 (en) * 2003-12-18 2014-06-03 Ge Healthcare Limited Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via isocyanate using azides and carbon-isotope monoxide
WO2006134424A2 (en) * 2004-12-03 2006-12-21 Ge Healthcare Limited Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled acids by photo-induced free radical carbonylation
GB0428020D0 (en) 2004-12-22 2005-01-26 Amersham Health As Stabilisation of radiopharmaceutical precursors
ES2386364T3 (es) * 2005-02-01 2012-08-17 Ge Healthcare Limited Procedimiento de uso de monóxido de carbono [11C] en la síntesis de marcado de compuestos marcados por 11C por carbonilación de radical libre inducida térmicamente
EP1863749A2 (en) * 2005-03-22 2007-12-12 GE Healthcare Limited Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via ketene using diazo compounds and carbon-isotope monoxide
CN101198359B (zh) * 2005-06-14 2011-06-22 日本医事物理股份有限公司 放射性诊断成像剂
EP1934160B1 (en) * 2005-08-31 2014-07-23 GE Healthcare Limited Method for the use of [11c]carbon monoxide in labeling synthesis of 11c-labelled ketones by photo-induced free radical carbonylation
JPWO2008056481A1 (ja) * 2006-11-09 2010-02-25 日本メジフィジックス株式会社 放射性画像診断剤
GB0922023D0 (en) * 2009-12-17 2010-02-03 Ge Healthcare Ltd Preparation of n-monofluoroalkyl compounds
US9951324B2 (en) 2010-02-25 2018-04-24 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
CN107362376A (zh) * 2010-07-27 2017-11-21 通用电气健康护理有限公司 放射性药物组合物
CN108042811A (zh) * 2012-11-15 2018-05-18 恩多塞特公司 用于治疗由psma表达细胞引起的疾病的共轭物
AU2014216515A1 (en) * 2013-02-15 2015-10-08 Thomas Jefferson University Kit for tumor imaging
LT4095130T (lt) 2013-10-18 2024-04-25 Novartis Ag Žymėti prostatos specifinio membranos antigeno (psma) inhibitoriai, jų naudojimas kaip vizualizavimo medžiagų ir farmacinių medžiagų prostatos vėžiui gydyti
US20150375901A1 (en) * 2014-06-30 2015-12-31 Karen J. Orlich Reusable, eco-friendly container for storing and dispensing food and beverage
US10188759B2 (en) 2015-01-07 2019-01-29 Endocyte, Inc. Conjugates for imaging
RU2624237C1 (ru) * 2016-10-26 2017-07-03 Федеральное государственное бюджетное учреждение "Государственный научный центр Российской Федерации - Федеральный медицинский биофизический центр имени А.И. Бурназяна" Радиофармацевтическая композиция для радиосиновэктомии и способ ее получения
US10486160B2 (en) 2017-08-21 2019-11-26 Bliss Industries, Llc Method of replacing hammers and spacers
USD905136S1 (en) 2018-03-05 2020-12-15 Bliss Industries, Llc Hammermill hammer
US10610870B2 (en) 2017-08-21 2020-04-07 Bliss Industries, Llc Hot and cold forming hammer and method of assembly
US10207274B1 (en) 2017-08-21 2019-02-19 Roger Young Non-forged hammermill hammer
US10478824B2 (en) 2017-08-21 2019-11-19 Bliss Industries, Llc System and method for installing hammers
USD861048S1 (en) 2017-12-06 2019-09-24 Roger Young Swing hammer
USD840447S1 (en) 2017-12-06 2019-02-12 Roger Young Swing hammer
USD839934S1 (en) 2017-12-06 2019-02-05 Roger Young Swing hammer
WO2022156908A1 (en) * 2021-01-25 2022-07-28 Vrije Universiteit Brussel Method for preparing a lyophilized composition

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US4497744A (en) * 1978-03-31 1985-02-05 Mallinckrodt, Inc. Gentisic acid salts as radiographic scanning agent stabilizers
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Also Published As

Publication number Publication date
ZA200506728B (en) 2006-10-25
AU2004210191A1 (en) 2004-08-19
MXPA05008356A (es) 2006-03-13
ES2355100T3 (es) 2011-03-22
AU2004210191B2 (en) 2007-08-23
NO20053754D0 (no) 2005-08-05
CA2514307A1 (en) 2004-08-19
JP2011132258A (ja) 2011-07-07
EP1590007B1 (en) 2010-11-10
JP2006528205A (ja) 2006-12-14
ATE487498T1 (de) 2010-11-15
CN100548387C (zh) 2009-10-14
NO20053754L (no) 2005-10-05
CN1767859A (zh) 2006-05-03
EP1590007A1 (en) 2005-11-02
WO2004069285A1 (en) 2004-08-19
DE602004029983D1 (de) 2010-12-23
US20070020177A1 (en) 2007-01-25
KR20050103221A (ko) 2005-10-27
EP1444990A1 (en) 2004-08-11
RU2005123799A (ru) 2006-03-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.