BR9809785A - Composto de ligação de receptor de calcitonina, reagente, agente de formação de imagem cintigráfica, composição, agente radio-terapêutico, complexo, kit para preparar uma preparação radio-farmacêutica, processos para rotular o reagente, para fabricar o reagente, e, uso do reagente - Google Patents

Composto de ligação de receptor de calcitonina, reagente, agente de formação de imagem cintigráfica, composição, agente radio-terapêutico, complexo, kit para preparar uma preparação radio-farmacêutica, processos para rotular o reagente, para fabricar o reagente, e, uso do reagente

Info

Publication number
BR9809785A
BR9809785A BR9809785-7A BR9809785A BR9809785A BR 9809785 A BR9809785 A BR 9809785A BR 9809785 A BR9809785 A BR 9809785A BR 9809785 A BR9809785 A BR 9809785A
Authority
BR
Brazil
Prior art keywords
reagent
radio
labeling
kit
processes
Prior art date
Application number
BR9809785-7A
Other languages
English (en)
Inventor
Richard T Dean
Larry R Bush
Daniel A Pearson
John Lister James
Original Assignee
Diatide Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diatide Inc filed Critical Diatide Inc
Publication of BR9809785A publication Critical patent/BR9809785A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"COMPOSTO DE LIGAçãO DE RECEPTOR DE CALCITONINA, REAGENTE, AGENTE DE FORMAçãO DE IMAGEM CINTIGRáFICA, COMPOSIçãO, AGENTE RADIO-TERAPêUTICO, KIT PARA PREPARAR UMA PREPARAçãO RADIO-FARMACêUTICA, PROCESSO PARA FABRICAR O REAGENTE, E, USO DO REAGENTE". Esta invenção refere-se a reagentes de ligação de receptor de calcitonina compreendendo compostos que são covalentemente ligados a um quelator radio-metal. A invenção é corporificada como derivados de peptídeo de ligação de receptor de calcitonina, de calcitonina, que podem ser radio-rotulados com um isótopo apropriado e usados como agentes radio-diagnósticos ou radio-terapêuticos. Os processos e kits para fabricar, radio-rotular e usar estes reagentes de modo diagnóstico e terapêutico em um corpo de mamífero são também providos.
BR9809785-7A 1997-05-01 1998-05-01 Composto de ligação de receptor de calcitonina, reagente, agente de formação de imagem cintigráfica, composição, agente radio-terapêutico, complexo, kit para preparar uma preparação radio-farmacêutica, processos para rotular o reagente, para fabricar o reagente, e, uso do reagente BR9809785A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/847,007 US6083480A (en) 1997-05-01 1997-05-01 Calcitonin receptor binding reagents
PCT/US1998/008864 WO1998049196A1 (en) 1997-05-01 1998-05-01 Calcitonin receptor-binding peptides

Publications (1)

Publication Number Publication Date
BR9809785A true BR9809785A (pt) 2000-06-20

Family

ID=25299537

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809785-7A BR9809785A (pt) 1997-05-01 1998-05-01 Composto de ligação de receptor de calcitonina, reagente, agente de formação de imagem cintigráfica, composição, agente radio-terapêutico, complexo, kit para preparar uma preparação radio-farmacêutica, processos para rotular o reagente, para fabricar o reagente, e, uso do reagente

Country Status (18)

Country Link
US (4) US6083480A (pt)
EP (1) EP0975669A1 (pt)
JP (1) JP3774238B2 (pt)
KR (1) KR20010020406A (pt)
CN (1) CN1254346A (pt)
AU (1) AU7470498A (pt)
BR (1) BR9809785A (pt)
CA (1) CA2289019A1 (pt)
HU (1) HUP0001477A3 (pt)
IL (1) IL132454A0 (pt)
NO (1) NO995299D0 (pt)
NZ (1) NZ500568A (pt)
PL (1) PL336761A1 (pt)
RO (1) RO120711B1 (pt)
RU (1) RU2205187C2 (pt)
SK (1) SK146499A3 (pt)
TW (1) TW553743B (pt)
WO (1) WO1998049196A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083480A (en) * 1997-05-01 2000-07-04 Diatide, Inc. Calcitonin receptor binding reagents
EP1390077B1 (en) 2001-05-02 2014-07-16 Purdue Research Foundation Treatment and diagnosis of macrophage mediated disease
US8043603B2 (en) 2002-02-07 2011-10-25 Endocyte, Inc. Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
US8043602B2 (en) 2002-02-07 2011-10-25 Endocyte, Inc. Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
PT2260875E (pt) 2002-05-06 2014-06-25 Endocyte Inc Agentes de imagiologia direcionados para recetor de folato
ATE534664T1 (de) * 2004-05-24 2011-12-15 Inst Cardiologie Montreal Markierte adrenomedullinderivate und deren verwendung zur bilddarstellung und therapie
EP1904183B1 (en) 2005-07-05 2014-10-15 Purdue Research Foundation Pharmaceutical composition for the treatment of osteoarthritis
EP1940473A2 (en) 2005-09-23 2008-07-09 Purdue Research Foundation Multiphoton in vivo flow cytometry method and device
US8685752B2 (en) 2006-11-03 2014-04-01 Purdue Research Foundation Ex vivo flow cytometry method and device
EP2567711A3 (en) 2007-02-07 2013-05-01 Purdue Research Foundation Positron emission tomography imaging method
CA2688308A1 (en) 2007-05-25 2008-12-04 Purdue Research Foundation Method of imaging localized infections
DK2389388T3 (en) * 2009-01-22 2017-05-01 Keybioscience Ag TREATMENT FOR Obesity
EP2588866A4 (en) * 2010-07-02 2014-01-22 Welcome Receptor Antibodies Pty Ltd DIAGNOSIS AND TREATMENT OF BRAIN TUMORS
EP3334466B1 (en) 2015-08-14 2020-05-13 Endocyte, Inc. Method of imaging with a chelating compound

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Publication number Priority date Publication date Assignee Title
JPS51128993A (en) * 1975-05-01 1976-11-10 Tanpakushitsu Kenkyu Shiyoureikai Process for preparing new polypeptides
JPS5850213B2 (ja) * 1977-06-20 1983-11-09 株式会社第一ラジオアイソト−プ研究所 カルチトニンの定量法
US4663309A (en) * 1983-06-29 1987-05-05 University Patents, Inc. Novel peptide hormones with calcitonin-like activity
JPS61112099A (ja) * 1984-11-06 1986-05-30 Mitsubishi Petrochem Co Ltd 新規ポリペプチド及びその製造法
US4764589A (en) * 1987-05-26 1988-08-16 Rorer Pharmaceutical Corporation [N-alpha-acyl,8-glycine, des-19-leucine]-calcitonin
GB2218102B (en) * 1988-04-08 1992-09-16 Sandoz Ltd Calcitonin peptide derivatives
US4988496A (en) * 1988-05-31 1991-01-29 Neorx Corporation Metal radionuclide chelating compounds for improved chelation kinetics
AU629552B2 (en) * 1988-06-16 1992-10-08 Teijin Limited S-sulfonated calcitonin derivatives
DE68912090T2 (de) * 1988-11-24 1994-06-16 Mitsubishi Petrochemical Co Calcitonin-Derivate und deren Salze.
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
US7238340B1 (en) * 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
JP4143118B2 (ja) * 1993-02-23 2008-09-03 ブリガム・アンド・ウイミンズ・ホスピタル・インコーポレイテッド カルシウム受容体活性化分子およびその関連物
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
US5698521A (en) * 1995-04-04 1997-12-16 Zymogenetics, Inc. Native calcitonin mimetics
US6083480A (en) * 1997-05-01 2000-07-04 Diatide, Inc. Calcitonin receptor binding reagents

Also Published As

Publication number Publication date
SK146499A3 (en) 2000-08-14
IL132454A0 (en) 2001-03-19
US6509001B1 (en) 2003-01-21
JP3774238B2 (ja) 2006-05-10
WO1998049196A1 (en) 1998-11-05
CA2289019A1 (en) 1998-11-05
US6083480A (en) 2000-07-04
PL336761A1 (en) 2000-07-17
US6086850A (en) 2000-07-11
NO995299L (no) 1999-10-29
NO995299D0 (no) 1999-10-29
JP2001523257A (ja) 2001-11-20
TW553743B (en) 2003-09-21
NZ500568A (en) 2001-04-27
KR20010020406A (ko) 2001-03-15
EP0975669A1 (en) 2000-02-02
CN1254346A (zh) 2000-05-24
RU2205187C2 (ru) 2003-05-27
US6479032B1 (en) 2002-11-12
RO120711B1 (ro) 2006-06-30
AU7470498A (en) 1998-11-24
HUP0001477A2 (hu) 2000-09-28
HUP0001477A3 (en) 2001-10-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A,9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1942 DE 25 - 03 - 2008.