KR20050062575A - 신규한 1,4-디아자바이사이클로알칸 유도체, 이의 제법 및용도 - Google Patents

신규한 1,4-디아자바이사이클로알칸 유도체, 이의 제법 및용도 Download PDF

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Publication number
KR20050062575A
KR20050062575A KR1020057005508A KR20057005508A KR20050062575A KR 20050062575 A KR20050062575 A KR 20050062575A KR 1020057005508 A KR1020057005508 A KR 1020057005508A KR 20057005508 A KR20057005508 A KR 20057005508A KR 20050062575 A KR20050062575 A KR 20050062575A
Authority
KR
South Korea
Prior art keywords
diazabicyclo
nonane
oxadiazol
thiadiazol
methyl
Prior art date
Application number
KR1020057005508A
Other languages
English (en)
Korean (ko)
Inventor
단 페터스
군나르 엠 올센
엘제베트 외스테르가아트 닐센
티노 다이링 외르겐센
필립 케이 아링
Original Assignee
뉴로서치 에이/에스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 뉴로서치 에이/에스 filed Critical 뉴로서치 에이/에스
Publication of KR20050062575A publication Critical patent/KR20050062575A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1020057005508A 2002-09-30 2003-09-29 신규한 1,4-디아자바이사이클로알칸 유도체, 이의 제법 및용도 KR20050062575A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200201456 2002-09-30
DKPA200201456 2002-09-30
DKPA200201738 2002-11-11
DKPA200201738 2002-11-11

Publications (1)

Publication Number Publication Date
KR20050062575A true KR20050062575A (ko) 2005-06-23

Family

ID=34828377

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057005508A KR20050062575A (ko) 2002-09-30 2003-09-29 신규한 1,4-디아자바이사이클로알칸 유도체, 이의 제법 및용도

Country Status (12)

Country Link
JP (1) JP4711391B2 (de)
KR (1) KR20050062575A (de)
CN (1) CN1326857C (de)
BR (1) BR0314183A (de)
HK (1) HK1081954A1 (de)
IL (1) IL166821A (de)
IS (1) IS7829A (de)
MX (1) MXPA05003344A (de)
NO (1) NO20052124L (de)
PT (1) PT1551835E (de)
RU (1) RU2323218C2 (de)
SI (1) SI1551835T1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3019B1 (ar) * 2006-04-19 2016-09-05 Janssen Pharmaceutica Nv ثلاثي مستبدل 4،2،1-ثلاثي زولات
DK2032574T3 (da) * 2006-05-30 2010-09-20 Neurosearch As Hidtil ukendt 1,4-diaza-bicyclo[3.2.2]nonyloxadiazolyl-derivater og medicinsk anvendelse deraf
US8492378B2 (en) 2006-08-03 2013-07-23 Takeda Pharmaceutical Company Limited GSK-3β inhibitor
JP2010519193A (ja) * 2007-02-15 2010-06-03 アージェンタ ディスカバリー リミテッド Ｍ３ムスカリン受容体としての複素環式誘導体
JP6083818B2 (ja) 2011-11-18 2017-02-22 ヘプタレス セラピューティクス リミテッドＨｅｐｔａｒｅｓ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ ムスカリンｍ１受容体アゴニスト
GB201513743D0 (en) 2015-08-03 2015-09-16 Heptares Therapeutics Ltd Muscarinic agonists
DK3386511T3 (da) * 2015-12-10 2021-07-05 Ptc Therapeutics Inc Fremgangsmåder til behandling af huntingtons sygdom
CN108727293B (zh) * 2016-09-18 2021-05-11 广西师范大学 1，2，8-氧代二氮杂环壬-9-酮衍生物及其合成方法
GB201617454D0 (en) 2016-10-14 2016-11-30 Heptares Therapeutics Limited Pharmaceutical compounds
GB201810239D0 (en) 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819960D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB202020191D0 (en) 2020-12-18 2021-02-03 Heptares Therapeutics Ltd Pharmaceutical compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ226000A (en) * 1987-09-10 1991-06-25 Merck Sharp & Dohme Oxadiazolyl-azabicycloheptanes and pharmaceutical compositions
US5478939A (en) * 1994-07-20 1995-12-26 American Cyanamid Company (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives
FR2786770B1 (fr) * 1998-12-04 2001-01-19 Synthelabo Derives de 1,4-diazabicyclo[3.2.2.]nonane, leur preparation et leur application en therapeutique
CA2379149A1 (en) * 1999-07-09 2001-01-18 Ortho-Mcneil Pharmaceutical, Inc. Neurotrophic pyrrolidines and piperidines, and related compositions and methods
FR2804430B1 (fr) * 2000-01-28 2002-03-22 Sanofi Synthelabo Derives de 4-heteroaryl-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique
FR2809732B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo DERIVES DE 4(-2-PHENYLTHIAZOL-5-yl)-1,4-DIAZABICYCLO-[3.2.2] NONANE, LEUR PREPARATION ET LEUR APPLICATION ENTHERAPEUTIQUE
FR2809731B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique
US20020086871A1 (en) * 2000-12-29 2002-07-04 O'neill Brian Thomas Pharmaceutical composition for the treatment of CNS and other disorders
FR2832713B1 (fr) * 2001-11-23 2004-02-13 Sanofi Synthelabo Derives de 4-(1,3,4-thiadiazol-2-yl)-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
CN1684965A (zh) 2005-10-19
IL166821A (en) 2009-06-15
JP4711391B2 (ja) 2011-06-29
MXPA05003344A (es) 2005-11-23
NO20052124D0 (no) 2005-04-29
IL166821A0 (en) 2006-01-15
JP2006503062A (ja) 2006-01-26
PT1551835E (pt) 2007-03-30
SI1551835T1 (sl) 2007-06-30
BR0314183A (pt) 2005-08-09
HK1081954A1 (en) 2006-05-26
CN1326857C (zh) 2007-07-18
IS7829A (is) 2005-04-28
RU2005105048A (ru) 2005-11-20
NO20052124L (no) 2005-06-29
RU2323218C2 (ru) 2008-04-27

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