KR20040094833A - 비-항균성 테트라사이클린 동족체의 용도 및 박테리아외독소의 치료를 위한 이의 제형 - Google Patents

비-항균성 테트라사이클린 동족체의 용도 및 박테리아외독소의 치료를 위한 이의 제형 Download PDF

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Publication number
KR20040094833A
KR20040094833A KR10-2004-7014877A KR20047014877A KR20040094833A KR 20040094833 A KR20040094833 A KR 20040094833A KR 20047014877 A KR20047014877 A KR 20047014877A KR 20040094833 A KR20040094833 A KR 20040094833A
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KR
South Korea
Prior art keywords
tetracycline
cmt
exotoxin
pharmaceutically acceptable
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR10-2004-7014877A
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English (en)
Korean (ko)
Inventor
론 엠. 골럽
스티븐 지. 워커
Original Assignee
더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕 filed Critical 더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕
Publication of KR20040094833A publication Critical patent/KR20040094833A/ko
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR10-2004-7014877A 2002-03-29 2003-03-27 비-항균성 테트라사이클린 동족체의 용도 및 박테리아외독소의 치료를 위한 이의 제형 Ceased KR20040094833A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36847802P 2002-03-29 2002-03-29
US60/368,478 2002-03-29
PCT/US2003/009570 WO2003082011A1 (en) 2002-03-29 2003-03-27 Use of non-antibacterial tetracycline analogs and formulations thereof for the treatment of bacterial exotoxins

Publications (1)

Publication Number Publication Date
KR20040094833A true KR20040094833A (ko) 2004-11-10

Family

ID=28675499

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2004-7014877A Ceased KR20040094833A (ko) 2002-03-29 2003-03-27 비-항균성 테트라사이클린 동족체의 용도 및 박테리아외독소의 치료를 위한 이의 제형

Country Status (11)

Country Link
US (2) US20040014731A1 (https=)
EP (2) EP2250887B1 (https=)
JP (1) JP2005521701A (https=)
KR (1) KR20040094833A (https=)
AT (1) ATE489081T1 (https=)
AU (1) AU2003226112B9 (https=)
CA (1) CA2475202A1 (https=)
DE (1) DE60335093D1 (https=)
ES (1) ES2359346T3 (https=)
NZ (1) NZ534950A (https=)
WO (1) WO2003082011A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004091483A2 (en) * 2003-04-07 2004-10-28 Shire Laboratories, Inc. Once daily formulations of tetracyclines
US20060252731A1 (en) * 2005-05-06 2006-11-09 Pfeiffer David F Methods of treating recurrent aphthous stomatitis
US20070015738A1 (en) * 2005-07-15 2007-01-18 Walker Stephen G Use of non-antibacterial tetracycline formulations for inhibiting bacterial spores from becoming infectious vegetative cells
WO2007011699A2 (en) * 2005-07-15 2007-01-25 Research Foundation Of State University Of New York Use of non-antibacterial tetracycline formulations for inhibiting bacterial spores
US8440646B1 (en) * 2006-10-11 2013-05-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of Bacillus anthracis infections
AU2016235151A1 (en) 2015-03-24 2017-10-12 Paratek Pharmaceuticals, Inc. Minocycline compounds for biodefense
US20250177318A1 (en) * 2022-01-04 2025-06-05 The Research Foundation For The State University Of New York Cmt-3 formulations and methods of using the same

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (https=) * 1960-05-23 1966-05-25
GB1034934A (en) * 1962-10-29 1966-07-06 American Cyanamid Co New tetracycline compounds and manufacture thereof
DE2011281A1 (en) * 1970-03-10 1971-09-16 Leningradskij Nautschno-Issledowatelskij Institut Antibiotikow, Leningrad (Sowjetunion) Polyantibiotic with antimicrobial activity
US4935412A (en) 1983-12-29 1990-06-19 The Research Foundation Of State University Of New York Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same
US4925833A (en) 1983-12-29 1990-05-15 The Research Foundation Of State University Of New York Use of tetracycline to enhance bone protein synthesis and/or treatment of osteoporosis
US4704383A (en) * 1983-12-29 1987-11-03 The Research Foundation Of State University Of New York Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same
US4666897A (en) 1983-12-29 1987-05-19 Research Foundation Of State University Inhibition of mammalian collagenolytic enzymes by tetracyclines
EP0256713A3 (en) * 1986-08-06 1989-02-15 Merck & Co. Inc. Therapeutic human antipseudomonas aeruginosa antibodies
US5308839A (en) * 1989-12-04 1994-05-03 The Research Foundation Of State University Of New York Composition comprising non-steroidal anti-inflammatory agent tenidap and effectively non-antibacterial tetracycline
US5045538A (en) 1990-06-28 1991-09-03 The Research Foundation Of State University Of New York Inhibition of wasting and protein degradation of mammalian muscle by tetracyclines
DK0599397T3 (da) 1992-11-17 1996-09-16 Univ New York State Res Found Tetracycliner, herunder non-mikrobielle, kemisk-modificerede tetracycliner, inhiberer overdreven collagentværbinding ved diabetes
US5523297A (en) 1993-03-02 1996-06-04 The Research Foundation Of State University Of New York Inhibition of excessive phospholipase A2 activity and/or production by non-antimicrobial tetracyclines
US6043231A (en) 1993-03-02 2000-03-28 The Research Foundation Of State Univ. Of New York Inhibition of excessive phospholipase A2 activity and/or production by non-antimicrobial tetracyclines
EP0736302A3 (en) * 1995-03-23 1997-06-04 Stichting Rega V Z W Protease inhibitors, DNA construction for protease expression and a method for measuring proteases and / or protease inhibitors
US5744453A (en) * 1996-01-05 1998-04-28 Mintz; Clifford S. Polyamine conjugates for treatment of infection
US6245735B1 (en) * 1996-07-29 2001-06-12 The Brigham And Women's Hospital, Inc. Methods and products for treating pseudomonas infection
US5789395A (en) * 1996-08-30 1998-08-04 The Research Foundation Of State University Of New York Method of using tetracycline compounds for inhibition of endogenous nitric oxide production
US6063775A (en) * 1997-04-29 2000-05-16 Berman; Charles L. Retardation of metalloproteinase incidental to HIV and/or AIDS
US6277061B1 (en) * 1998-03-31 2001-08-21 The Research Foundation Of State University Of New York Method of inhibiting membrane-type matrix metalloproteinase
US6015804A (en) * 1998-09-11 2000-01-18 The Research Foundation Of State University Of New York Method of using tetracycline compounds to enhance interleukin-10 production
US6384081B2 (en) * 1998-10-09 2002-05-07 Charles L. Berman Treatment of diseases of the eye characterized by the formation of metalloproteinase
DE69932846T2 (de) * 1998-11-18 2007-03-15 Collagenex Pharmaceuticals, Inc. Neue 4-dedimethylaminotetracyclinderivate
US6506740B1 (en) * 1998-11-18 2003-01-14 Robert A. Ashley 4-dedimethylaminotetracycline derivatives
US6172040B1 (en) * 1999-05-28 2001-01-09 A. Satyanarayan Naidu Immobilized lactoferrin antimicrobial agents and the use thereof

Also Published As

Publication number Publication date
ES2359346T3 (es) 2011-05-20
JP2005521701A (ja) 2005-07-21
AU2003226112B9 (en) 2008-06-05
AU2003226112B2 (en) 2008-05-01
DE60335093D1 (de) 2011-01-05
NZ534950A (en) 2006-04-28
WO2003082011A1 (en) 2003-10-09
EP1496742A1 (en) 2005-01-19
ATE489081T1 (de) 2010-12-15
EP1496742B1 (en) 2010-11-24
EP2250887B1 (en) 2013-04-24
EP2250887A2 (en) 2010-11-17
AU2003226112A1 (en) 2003-10-13
CA2475202A1 (en) 2003-10-09
US20080233151A1 (en) 2008-09-25
EP1496742A4 (en) 2007-04-11
US20040014731A1 (en) 2004-01-22
EP2250887A3 (en) 2010-11-24

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