KR20040070343A - 시험관내 미세기관 및 이에 관련된 용도 - Google Patents

시험관내 미세기관 및 이에 관련된 용도 Download PDF

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Publication number
KR20040070343A
KR20040070343A KR10-2004-7006068A KR20047006068A KR20040070343A KR 20040070343 A KR20040070343 A KR 20040070343A KR 20047006068 A KR20047006068 A KR 20047006068A KR 20040070343 A KR20040070343 A KR 20040070343A
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KR
South Korea
Prior art keywords
organ
micro
explant
cell
cells
Prior art date
Application number
KR10-2004-7006068A
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English (en)
Korean (ko)
Inventor
에두아르도엔. 미트라니
Original Assignee
이슘 리서치 디벨롭먼트 컴퍼니 오브 더 히브루 유니버시티 오브 예루살렘
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이슘 리서치 디벨롭먼트 컴퍼니 오브 더 히브루 유니버시티 오브 예루살렘 filed Critical 이슘 리서치 디벨롭먼트 컴퍼니 오브 더 히브루 유니버시티 오브 예루살렘
Priority claimed from PCT/IL2001/000976 external-priority patent/WO2003035851A1/fr
Publication of KR20040070343A publication Critical patent/KR20040070343A/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR10-2004-7006068A 2001-10-23 2001-10-23 시험관내 미세기관 및 이에 관련된 용도 KR20040070343A (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IL2001/000976 WO2003035851A1 (fr) 2001-10-23 2001-10-23 Micro-organes in vitro, et utilisations correspondantes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020097010888A Division KR100970195B1 (ko) 2001-10-23 2001-10-23 시험관내 미세기관 및 이에 관련된 용도

Publications (1)

Publication Number Publication Date
KR20040070343A true KR20040070343A (ko) 2004-08-07

Family

ID=32676735

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020097010888A KR100970195B1 (ko) 2001-10-23 2001-10-23 시험관내 미세기관 및 이에 관련된 용도
KR10-2004-7006068A KR20040070343A (ko) 2001-10-23 2001-10-23 시험관내 미세기관 및 이에 관련된 용도

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020097010888A KR100970195B1 (ko) 2001-10-23 2001-10-23 시험관내 미세기관 및 이에 관련된 용도

Country Status (5)

Country Link
JP (1) JP2005506084A (fr)
KR (2) KR100970195B1 (fr)
CN (1) CN1582330A (fr)
CA (1) CA2464460A1 (fr)
IL (1) IL161472A0 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8501396B2 (en) 2001-11-05 2013-08-06 Medgenics Medical Israel Ltd. Dermal micro-organs, methods and apparatuses for producing and using the same
US8088568B2 (en) 2001-11-05 2012-01-03 Medgentics, Inc. Dermal micro-organs, methods and apparatuses for producing and using the same
US7468242B2 (en) 2001-11-05 2008-12-23 Medgenics, Inc. Dermal micro organs, methods and apparatuses for producing and using the same
EP2377403A1 (fr) 2003-05-01 2011-10-19 Medgenics, Inc. Micro-organe dermique génétiquement modifié exprimant le facteur VIII
KR101449587B1 (ko) 2006-09-14 2014-10-10 메드제닉스 메디칼 이스라엘 리미티드 장기 지속형 약물 제형
US8454948B2 (en) 2006-09-14 2013-06-04 Medgenics Medical Israel Ltd. Long lasting drug formulations
US8771930B2 (en) * 2007-05-18 2014-07-08 Lifeline Scientific, Inc. Ex vivo methods for testing toxicity of substances using donated human organs or tissues
JP2013532152A (ja) * 2010-06-15 2013-08-15 メドジェニクス・メディカル・イスラエル・リミテッド 長期持続性の医薬製剤
US9951313B2 (en) * 2011-06-02 2018-04-24 President And Fellows Of Harvard College Methods and uses for ex vivo tissue culture systems
WO2013096741A2 (fr) * 2011-12-23 2013-06-27 Anthrogenesis Corporation Organoïdes comprenant un échafaudage vasculaire placentaire repeuplé et décellularisé
CN105334196B (zh) * 2015-09-24 2018-08-24 华东师范大学 一种检测3D类器官中P-gp介导的Rh123转运的方法及应用
RU2631005C1 (ru) * 2016-10-06 2017-09-15 Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет им. Н.И. Пирогова" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России) Способ культивирования клеток слюнной железы человека
CN109082402B (zh) * 2018-08-06 2021-08-17 复旦大学 一种aav-dj型腺相关病毒体外高效感染类器官的用途
CN113774018B (zh) * 2021-08-30 2023-09-05 吉林大学 一种大鼠心肌细胞和心肌成纤维细胞分离和培养的方法

Also Published As

Publication number Publication date
KR100970195B1 (ko) 2010-07-14
CN1582330A (zh) 2005-02-16
IL161472A0 (en) 2004-09-27
CA2464460A1 (fr) 2003-05-01
KR20090060381A (ko) 2009-06-11
JP2005506084A (ja) 2005-03-03

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