KR20040044990A - 구강내 붕해성 발데콕시브 조성물 - Google Patents

구강내 붕해성 발데콕시브 조성물 Download PDF

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Publication number
KR20040044990A
KR20040044990A KR10-2004-7004373A KR20047004373A KR20040044990A KR 20040044990 A KR20040044990 A KR 20040044990A KR 20047004373 A KR20047004373 A KR 20047004373A KR 20040044990 A KR20040044990 A KR 20040044990A
Authority
KR
South Korea
Prior art keywords
valdecoxib
pharmaceutically acceptable
composition
mouth
saccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR10-2004-7004373A
Other languages
English (en)
Korean (ko)
Inventor
트랑 티 레
블레이크 씨 루드윅
조셉 피 레오
우데이 제이 샤
겐 야마모토
Original Assignee
파마시아 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 파마시아 코포레이션 filed Critical 파마시아 코포레이션
Publication of KR20040044990A publication Critical patent/KR20040044990A/ko
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR10-2004-7004373A 2001-09-26 2002-09-23 구강내 붕해성 발데콕시브 조성물 Ceased KR20040044990A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32535601P 2001-09-26 2001-09-26
US60/325,356 2001-09-26
PCT/US2002/030161 WO2003026623A1 (en) 2001-09-26 2002-09-23 Intraorally disintegrating valdecoxib compositions

Publications (1)

Publication Number Publication Date
KR20040044990A true KR20040044990A (ko) 2004-05-31

Family

ID=23267542

Family Applications (2)

Application Number Title Priority Date Filing Date
KR10-2004-7004373A Ceased KR20040044990A (ko) 2001-09-26 2002-09-23 구강내 붕해성 발데콕시브 조성물
KR10-2004-7004334A Ceased KR20040058189A (ko) 2001-09-26 2002-09-23 관능상 허용가능한 경구내 붕해 조성물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR10-2004-7004334A Ceased KR20040058189A (ko) 2001-09-26 2002-09-23 관능상 허용가능한 경구내 붕해 조성물

Country Status (25)

Country Link
US (1) US20030181501A1 (enExample)
EP (2) EP1429736A2 (enExample)
JP (2) JP2005506987A (enExample)
KR (2) KR20040044990A (enExample)
CN (2) CN1633281A (enExample)
AP (2) AP2004002998A0 (enExample)
AR (1) AR037239A1 (enExample)
BR (2) BR0212778A (enExample)
CA (2) CA2461044A1 (enExample)
CO (2) CO5570684A2 (enExample)
EA (2) EA200400357A1 (enExample)
EC (1) ECSP045029A (enExample)
GE (1) GEP20063856B (enExample)
HK (1) HK1079988A1 (enExample)
IL (2) IL160855A0 (enExample)
IS (2) IS7178A (enExample)
MA (2) MA27682A1 (enExample)
MX (2) MXPA04002652A (enExample)
NO (2) NO20041258L (enExample)
OA (2) OA13060A (enExample)
PL (2) PL369297A1 (enExample)
TN (2) TNSN04045A1 (enExample)
WO (2) WO2003026697A2 (enExample)
YU (1) YU34804A (enExample)
ZA (2) ZA200401953B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005002557A1 (en) * 2003-07-03 2005-01-13 Warner-Lambert Company Llc Pharmaceutical compositions including an ether and selective cox-2 inhibitor and uses thereof
US20050186271A1 (en) * 2004-02-24 2005-08-25 Sheskey Paul J. Process for dispersing a fluid in a mass of solid particles
WO2006016602A1 (ja) * 2004-08-10 2006-02-16 Ajinomoto Co., Inc. 苦味の低減したナテグリニド含有製剤
WO2006070845A1 (ja) * 2004-12-28 2006-07-06 Eisai R & D Management Co., Ltd. 速崩壊性錠剤及びその製造方法
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
KR20080080318A (ko) * 2005-12-20 2008-09-03 에자이 알앤드디 매니지먼트 가부시키가이샤 지용성 약물을 함유하는 구강내 속붕정
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8535714B2 (en) 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8252329B2 (en) 2007-01-05 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8202535B2 (en) * 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US20090136570A1 (en) * 2006-01-20 2009-05-28 Bhagwant Rege Taste-Masked Tablets and Granules
US20070196494A1 (en) * 2006-02-17 2007-08-23 Arnaud Grenier Low-friability, patient-friendly orally disintegrating formulations
WO2007142811A2 (en) * 2006-05-19 2007-12-13 Somaxon Pharmaceuticals, Inc. Low dose doxepin formulations, including buccal, sublingual and fastmelt formulations, and uses of the same to treat insomnia
KR20100033400A (ko) * 2007-06-06 2010-03-29 바스프 에스이 급속 붕해 정제의 제조를 위한 제약 제제
EP2164460B1 (de) * 2007-06-06 2017-08-09 Basf Se Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten
EP2164461B1 (de) * 2007-06-06 2013-01-23 Basf Se Kau- und lutsch-tabletten
EP2164462B1 (de) * 2007-06-06 2017-05-31 Basf Se Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten
ES2534433T3 (es) * 2007-08-07 2015-04-22 Acelrx Pharmaceuticals, Inc. Composiciones que comprenden sufentanilo y triazolam para sedación y analgesia operatorias utilizando formas farmacéuticas transmucosas orales
US20110086070A1 (en) * 2008-03-24 2011-04-14 Munish Talwar Orally disintegrating compositions of rhein or diacerein
US8945592B2 (en) * 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
EP2368544A4 (en) * 2008-11-25 2012-08-15 Mitsubishi Tanabe Pharma Corp RASCH IN MOUTH DAMAGING TABLET AND METHOD FOR THEIR MANUFACTURE
CA2765033C (en) 2009-06-12 2020-07-14 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
US20110091544A1 (en) * 2009-10-16 2011-04-21 Acelrx Pharmaceuticals, Inc. Compositions and Methods for Mild Sedation, Anxiolysis and Analgesia in the Procedural Setting
FR2968995B1 (fr) * 2010-12-16 2013-03-22 Sanofi Aventis Composition pharmaceutioue pour une administration par voie orale destinee a eviter le mesusage
CN106822007B (zh) 2015-09-11 2021-12-31 西姆莱斯股份公司 口服制剂

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5576014A (en) * 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
US5633272A (en) * 1995-02-13 1997-05-27 Talley; John J. Substituted isoxazoles for the treatment of inflammation
SK74396A3 (en) * 1995-06-13 1997-04-09 American Home Prod Organoleptically acceptable oral pharmaceutical compositions
DK0855988T3 (da) * 1995-10-20 2002-08-19 Upjohn Co Blisterpakning
CZ291463B6 (cs) * 1996-05-17 2003-03-12 Merck And Co., Inc. Farmaceutický prostředek
EP0863134A1 (en) * 1997-03-07 1998-09-09 Merck Frosst Canada Inc. 2-(3,5-difluorophenyl)-3-(4-(methyl-sulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cyclooxygenase-2
US6465009B1 (en) * 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
WO2001041761A2 (en) * 1999-12-08 2001-06-14 Pharmacia Corporation Valdecoxib compositions
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
US6800297B2 (en) * 2000-06-15 2004-10-05 Acusphere, Inc. Porous COX-2 inhibitor matrices and methods of manufacture thereof
DE60120710T2 (de) * 2000-08-18 2007-06-14 Pharmacia Corp. Schnell zerfallende orale arzneizubereitung enthaltend valdecoxib
CN1638739A (zh) * 2000-08-18 2005-07-13 法玛西雅厄普约翰美国公司 治疗成瘾性障碍的化合物

Also Published As

Publication number Publication date
ZA200402364B (en) 2005-01-13
YU34804A (sh) 2006-08-17
BR0212778A (pt) 2004-12-07
CA2461630A1 (en) 2003-04-03
CO5570684A2 (es) 2005-10-31
PL369298A1 (en) 2005-04-18
WO2003026697A3 (en) 2003-07-03
JP2005506987A (ja) 2005-03-10
KR20040058189A (ko) 2004-07-03
WO2003026697A2 (en) 2003-04-03
MA27682A1 (fr) 2006-01-02
AR037239A1 (es) 2004-11-03
AP2004002998A0 (en) 2004-03-31
EP1429736A2 (en) 2004-06-23
MA27542A1 (fr) 2005-10-03
GEP20063856B (en) 2006-06-26
JP2005512964A (ja) 2005-05-12
AP2004002999A0 (en) 2004-03-31
WO2003026623A8 (en) 2004-09-30
HK1079988A1 (zh) 2006-04-21
OA12707A (en) 2006-06-26
US20030181501A1 (en) 2003-09-25
CN1633281A (zh) 2005-06-29
NO20041258L (no) 2003-03-27
EA200400357A1 (ru) 2004-08-26
CO5570659A2 (es) 2005-10-31
IL160855A0 (en) 2004-08-31
EA200400352A1 (ru) 2004-12-30
ECSP045029A (es) 2004-04-28
BR0212861A (pt) 2004-10-05
IS7178A (is) 2004-03-11
OA13060A (en) 2006-11-10
IS7177A (is) 2004-03-11
TNSN04045A1 (fr) 2006-06-01
CA2461044A1 (en) 2003-04-03
MXPA04002798A (es) 2004-07-05
WO2003026623A1 (en) 2003-04-03
CN1703203A (zh) 2005-11-30
IL160848A0 (en) 2004-08-31
TNSN04047A1 (fr) 2006-06-01
PL369297A1 (en) 2005-04-18
MXPA04002652A (es) 2004-06-07
NO20041532L (no) 2004-04-15
EP1490035A1 (en) 2004-12-29
ZA200401953B (en) 2005-05-09

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Legal Events

Date Code Title Description
A201 Request for examination
PA0105 International application

Patent event date: 20040325

Patent event code: PA01051R01D

Comment text: International Patent Application

PA0201 Request for examination
PG1501 Laying open of application
E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20051027

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20060405

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20051027

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I