GEP20063856B - Organoleptically acceptable intraorally disintegrating compositions - Google Patents

Organoleptically acceptable intraorally disintegrating compositions

Info

Publication number
GEP20063856B
GEP20063856B GE5525A GEAP2002005525A GEP20063856B GE P20063856 B GEP20063856 B GE P20063856B GE 5525 A GE5525 A GE 5525A GE AP2002005525 A GEAP2002005525 A GE AP2002005525A GE P20063856 B GEP20063856 B GE P20063856B
Authority
GE
Georgia
Prior art keywords
organoleptically acceptable
organoleptically
disintegrating compositions
intraorally disintegrating
composition
Prior art date
Application number
GE5525A
Other languages
English (en)
Inventor
Trang T Le
Blake C Ludwig
Joseph P Reo
J Shah Uday
Ken Yamamoto
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of GEP20063856B publication Critical patent/GEP20063856B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GE5525A 2001-09-26 2002-09-23 Organoleptically acceptable intraorally disintegrating compositions GEP20063856B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32535601P 2001-09-26 2001-09-26

Publications (1)

Publication Number Publication Date
GEP20063856B true GEP20063856B (en) 2006-06-26

Family

ID=23267542

Family Applications (1)

Application Number Title Priority Date Filing Date
GE5525A GEP20063856B (en) 2001-09-26 2002-09-23 Organoleptically acceptable intraorally disintegrating compositions

Country Status (25)

Country Link
US (1) US20030181501A1 (enExample)
EP (2) EP1429736A2 (enExample)
JP (2) JP2005512964A (enExample)
KR (2) KR20040044990A (enExample)
CN (2) CN1703203A (enExample)
AP (2) AP2004002998A0 (enExample)
AR (1) AR037239A1 (enExample)
BR (2) BR0212861A (enExample)
CA (2) CA2461044A1 (enExample)
CO (2) CO5570684A2 (enExample)
EA (2) EA200400357A1 (enExample)
EC (1) ECSP045029A (enExample)
GE (1) GEP20063856B (enExample)
HK (1) HK1079988A1 (enExample)
IL (2) IL160855A0 (enExample)
IS (2) IS7177A (enExample)
MA (2) MA27682A1 (enExample)
MX (2) MXPA04002652A (enExample)
NO (2) NO20041258L (enExample)
OA (2) OA12707A (enExample)
PL (2) PL369298A1 (enExample)
TN (2) TNSN04045A1 (enExample)
WO (2) WO2003026623A1 (enExample)
YU (1) YU34804A (enExample)
ZA (2) ZA200401953B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005002557A1 (en) * 2003-07-03 2005-01-13 Warner-Lambert Company Llc Pharmaceutical compositions including an ether and selective cox-2 inhibitor and uses thereof
US20050186271A1 (en) * 2004-02-24 2005-08-25 Sheskey Paul J. Process for dispersing a fluid in a mass of solid particles
JP5551852B2 (ja) * 2004-08-10 2014-07-16 味の素株式会社 苦味の低減したナテグリニド含有製剤
CN101115469A (zh) * 2004-12-28 2008-01-30 卫材R&D管理有限公司 速崩片及其制造方法
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
CN101340899A (zh) * 2005-12-20 2009-01-07 卫材R&D管理有限公司 含有脂溶性药物的口腔内速崩片
US8865743B2 (en) * 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8202535B2 (en) 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US8252329B2 (en) 2007-01-05 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8535714B2 (en) 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US20090136570A1 (en) * 2006-01-20 2009-05-28 Bhagwant Rege Taste-Masked Tablets and Granules
US20070196494A1 (en) * 2006-02-17 2007-08-23 Arnaud Grenier Low-friability, patient-friendly orally disintegrating formulations
JP2009537554A (ja) * 2006-05-19 2009-10-29 ソマクソン ファーマシューティカルズ インコーポレイテッド 不眠症を治療するための、口腔内、舌下および急速融解製剤を含む、低用量ドキセピン製剤、ならびにその使用
CN101707930B (zh) * 2007-06-06 2013-10-30 巴斯夫欧洲公司 用于制备快速崩解的片剂的药物配制剂
EP2164461B1 (de) * 2007-06-06 2013-01-23 Basf Se Kau- und lutsch-tabletten
CN102083410B (zh) * 2007-06-06 2013-04-17 巴斯夫欧洲公司 用于制备迅速崩解的片剂的药物制剂
CN102046147B (zh) * 2007-06-06 2013-03-20 巴斯夫欧洲公司 用于制备快速崩解的片剂的药物配制剂
DK2604257T3 (en) * 2007-08-07 2017-08-28 Acelrx Pharmaceuticals Inc ORAL TRANSMUCOSAL DOSAGE FORMS INCLUDING SUFENTANIL AND TRIAZOLAM
US20110086070A1 (en) * 2008-03-24 2011-04-14 Munish Talwar Orally disintegrating compositions of rhein or diacerein
US8945592B2 (en) * 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
WO2010061846A1 (ja) * 2008-11-25 2010-06-03 田辺三菱製薬株式会社 口腔内速崩壊性錠及びその製造方法
EP2440210A4 (en) 2009-06-12 2014-01-29 Meritage Pharma Inc METHOD FOR THE TREATMENT OF STOMACH DARM DISEASES
US20110091544A1 (en) * 2009-10-16 2011-04-21 Acelrx Pharmaceuticals, Inc. Compositions and Methods for Mild Sedation, Anxiolysis and Analgesia in the Procedural Setting
FR2968995B1 (fr) * 2010-12-16 2013-03-22 Sanofi Aventis Composition pharmaceutioue pour une administration par voie orale destinee a eviter le mesusage
CN106822007B (zh) 2015-09-11 2021-12-31 西姆莱斯股份公司 口服制剂

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5576014A (en) * 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
US5633272A (en) * 1995-02-13 1997-05-27 Talley; John J. Substituted isoxazoles for the treatment of inflammation
PE10898A1 (es) * 1995-06-13 1998-03-20 American Home Prod Formulaciones orales de etodolac s (+)-
ES2176489T3 (es) * 1995-10-20 2002-12-01 Upjohn Co Envase tipo blister.
KR100373622B1 (ko) * 1996-05-17 2003-07-12 머크 앤드 캄파니 인코포레이티드 사이클로옥시게나제-2로매개된질환의1일1회치료용조성물
EP0863134A1 (en) * 1997-03-07 1998-09-09 Merck Frosst Canada Inc. 2-(3,5-difluorophenyl)-3-(4-(methyl-sulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cyclooxygenase-2
US6465009B1 (en) * 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
CN1203852C (zh) * 1999-12-08 2005-06-01 法马西亚公司 维得克西组合物
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
US6800297B2 (en) * 2000-06-15 2004-10-05 Acusphere, Inc. Porous COX-2 inhibitor matrices and methods of manufacture thereof
CN1638739A (zh) * 2000-08-18 2005-07-13 法玛西雅厄普约翰美国公司 治疗成瘾性障碍的化合物
AU2001285011A1 (en) * 2000-08-18 2002-03-04 Pharmacia Corporation Rapidly disintegrating oral formulation of a cyclooxygenase-2 inhibitor

Also Published As

Publication number Publication date
AP2004002998A0 (en) 2004-03-31
EP1429736A2 (en) 2004-06-23
MXPA04002798A (es) 2004-07-05
PL369298A1 (en) 2005-04-18
EP1490035A1 (en) 2004-12-29
WO2003026697A3 (en) 2003-07-03
CO5570659A2 (es) 2005-10-31
BR0212861A (pt) 2004-10-05
AR037239A1 (es) 2004-11-03
BR0212778A (pt) 2004-12-07
IL160848A0 (en) 2004-08-31
TNSN04047A1 (fr) 2006-06-01
EA200400357A1 (ru) 2004-08-26
NO20041532L (no) 2004-04-15
ZA200401953B (en) 2005-05-09
IS7178A (is) 2004-03-11
JP2005512964A (ja) 2005-05-12
ECSP045029A (es) 2004-04-28
OA13060A (en) 2006-11-10
WO2003026623A1 (en) 2003-04-03
AP2004002999A0 (en) 2004-03-31
PL369297A1 (en) 2005-04-18
CO5570684A2 (es) 2005-10-31
YU34804A (sh) 2006-08-17
TNSN04045A1 (fr) 2006-06-01
IS7177A (is) 2004-03-11
OA12707A (en) 2006-06-26
ZA200402364B (en) 2005-01-13
CN1703203A (zh) 2005-11-30
CN1633281A (zh) 2005-06-29
MA27542A1 (fr) 2005-10-03
WO2003026623A8 (en) 2004-09-30
NO20041258L (no) 2003-03-27
US20030181501A1 (en) 2003-09-25
HK1079988A1 (zh) 2006-04-21
CA2461044A1 (en) 2003-04-03
WO2003026697A2 (en) 2003-04-03
IL160855A0 (en) 2004-08-31
CA2461630A1 (en) 2003-04-03
JP2005506987A (ja) 2005-03-10
KR20040058189A (ko) 2004-07-03
EA200400352A1 (ru) 2004-12-30
KR20040044990A (ko) 2004-05-31
MA27682A1 (fr) 2006-01-02
MXPA04002652A (es) 2004-06-07

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