KR20040018354A - 범용 다수-변이체 검출 시스템 - Google Patents

범용 다수-변이체 검출 시스템 Download PDF

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Publication number
KR20040018354A
KR20040018354A KR10-2003-7013577A KR20037013577A KR20040018354A KR 20040018354 A KR20040018354 A KR 20040018354A KR 20037013577 A KR20037013577 A KR 20037013577A KR 20040018354 A KR20040018354 A KR 20040018354A
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KR
South Korea
Prior art keywords
nucleic acid
reverse primer
sequence
forward primer
primer
Prior art date
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Abandoned
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KR10-2003-7013577A
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English (en)
Korean (ko)
Inventor
린다 앤드루스
카멘 니콜라 니콜스
Original Assignee
더 뉴욕 블러드 센터, 인코포레이티드
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Application filed by 더 뉴욕 블러드 센터, 인코포레이티드 filed Critical 더 뉴욕 블러드 센터, 인코포레이티드
Publication of KR20040018354A publication Critical patent/KR20040018354A/ko
Abandoned legal-status Critical Current

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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis
    • C12Q1/707Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6818Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
  • Small-Scale Networks (AREA)
KR10-2003-7013577A 2001-04-17 2002-04-17 범용 다수-변이체 검출 시스템 Abandoned KR20040018354A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28433401P 2001-04-17 2001-04-17
US60/284,334 2001-04-17
PCT/US2002/012035 WO2002083927A2 (en) 2001-04-17 2002-04-17 Universal multi-variant detection system

Publications (1)

Publication Number Publication Date
KR20040018354A true KR20040018354A (ko) 2004-03-03

Family

ID=23089805

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2003-7013577A Abandoned KR20040018354A (ko) 2001-04-17 2002-04-17 범용 다수-변이체 검출 시스템

Country Status (12)

Country Link
US (4) US7348164B2 (enExample)
EP (1) EP1390544B1 (enExample)
JP (1) JP4271944B2 (enExample)
KR (1) KR20040018354A (enExample)
CN (1) CN1279182C (enExample)
AT (1) ATE346958T1 (enExample)
AU (1) AU2002307359B2 (enExample)
CA (1) CA2444174A1 (enExample)
DE (1) DE60216445T2 (enExample)
ES (1) ES2278043T3 (enExample)
WO (1) WO2002083927A2 (enExample)
ZA (1) ZA200308906B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4271944B2 (ja) * 2001-04-17 2009-06-03 ニューヨーク・ブラッド・センター・インコーポレーテッド ユニバーサルマルチ変異体検出システム
WO2005075686A1 (en) * 2004-02-10 2005-08-18 Roche Diagnostics Gmbh New primers and probes for the detection of parvovirus b19
ES2759991T3 (es) 2004-09-30 2020-05-12 Gen Probe Inc Ensayo para detectar y cuantificar el VIH-1
AU2011253599B2 (en) * 2004-09-30 2013-12-12 Gen-Probe Incorporated Assay for detecting and quantifying HIV-1
US7833716B2 (en) 2006-06-06 2010-11-16 Gen-Probe Incorporated Tagged oligonucleotides and their use in nucleic acid amplification methods
US8198027B2 (en) 2006-12-21 2012-06-12 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
CN103003442B (zh) 2009-03-13 2018-10-09 康奈尔大学 一种通过微小rna表达水平评估人同种异体移植物状况的方法
EP2449132B1 (en) 2009-07-01 2015-05-13 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
US9746479B2 (en) 2010-03-09 2017-08-29 Cornell University Methods and compositions to predict and detect acute rejection
US9932628B2 (en) 2012-07-27 2018-04-03 Gen-Probe Incorporated Dual reference calibration method and system for quantifying polynucleotides
KR101377824B1 (ko) * 2012-11-19 2014-04-01 가톨릭대학교 산학협력단 수인성 바이러스 검출용 프라이머 및 이를 포함하는 검출 키트
CN103901000B (zh) * 2012-12-26 2016-09-28 江南大学 一种基于荧光共振能量转移检测伏马菌毒素b1的方法
US9758828B2 (en) 2013-01-31 2017-09-12 Cornell University Methods to detect, treat and prevent acute cellular rejection in kidney allografts
US9982301B2 (en) 2014-01-07 2018-05-29 Cornell University Urine mRNA profile and acute dysfunction of kidney allograft
WO2015157678A2 (en) 2014-04-10 2015-10-15 The Trustees Of The University Of Pennsylvania Use of micro-ribonucleic acid (mirna) to diagnose transplant rejection and tolerance of immunosuppression therapy
EP3253886A4 (en) 2015-02-03 2018-10-24 The Trustees of the University of Pennsylvania Novel methods for early identification of bone healing ability in injured patients
WO2017212023A1 (en) * 2016-06-10 2017-12-14 Roche Diagnostics Gmbh Compositions and methods for detection of hepatitis c virus genotype 3
CN110699353A (zh) * 2019-07-26 2020-01-17 安徽大学 一种靶向端粒的核酸探针
CN120265769A (zh) * 2023-10-08 2025-07-04 迈克生物股份有限公司 引物探针组合物、核酸检测方法及应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US6007983A (en) * 1995-12-22 1999-12-28 Visible Genetics Inc. Method and kit for evaluation of HIV mutations
WO1997039008A1 (en) * 1996-04-12 1997-10-23 The Public Health Research Institute Of The City Of New York, Inc. Detection probes, kits and assays
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits
AU3438999A (en) * 1999-05-07 2000-11-21 Nationales Zentrum Fur Retroviren Detection system for human immunodeficiency virus based on nucleic acid amplification
US6759193B2 (en) 1999-07-28 2004-07-06 The Government Of The Republic Of Singapore Detection of human hepatitis B virus surface antigen mutants by specific amplification and its application on gene chip
JP4271944B2 (ja) * 2001-04-17 2009-06-03 ニューヨーク・ブラッド・センター・インコーポレーテッド ユニバーサルマルチ変異体検出システム

Also Published As

Publication number Publication date
WO2002083927A2 (en) 2002-10-24
CN1509338A (zh) 2004-06-30
DE60216445D1 (de) 2007-01-11
CN1279182C (zh) 2006-10-11
ES2278043T3 (es) 2007-08-01
ATE346958T1 (de) 2006-12-15
EP1390544A2 (en) 2004-02-25
WO2002083927A3 (en) 2003-03-20
HK1065825A1 (zh) 2005-03-04
AU2002307359B2 (en) 2007-09-13
JP4271944B2 (ja) 2009-06-03
US20130288231A1 (en) 2013-10-31
EP1390544A4 (en) 2004-07-14
CA2444174A1 (en) 2002-10-24
US8192939B2 (en) 2012-06-05
US20120258446A1 (en) 2012-10-11
DE60216445T2 (de) 2007-10-31
ZA200308906B (en) 2004-11-23
US20110053138A1 (en) 2011-03-03
US7348164B2 (en) 2008-03-25
EP1390544B1 (en) 2006-11-29
JP2004532027A (ja) 2004-10-21
US20040053284A1 (en) 2004-03-18

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