ZA200308906B - Universal multi-variant detection system. - Google Patents
Universal multi-variant detection system. Download PDFInfo
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- ZA200308906B ZA200308906B ZA200308906A ZA200308906A ZA200308906B ZA 200308906 B ZA200308906 B ZA 200308906B ZA 200308906 A ZA200308906 A ZA 200308906A ZA 200308906 A ZA200308906 A ZA 200308906A ZA 200308906 B ZA200308906 B ZA 200308906B
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- South Africa
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- nucleic acid
- reverse primer
- forward primer
- sequence
- probe
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Classifications
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
- C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
Landscapes
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
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Applications Claiming Priority (1)
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| US28433401P | 2001-04-17 | 2001-04-17 |
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| EP (1) | EP1390544B1 (enExample) |
| JP (1) | JP4271944B2 (enExample) |
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| AU2002307359B2 (en) * | 2001-04-17 | 2007-09-13 | The New York Blood Center, Inc. | Universal multi-variant detection system |
| EP2251441B1 (en) * | 2004-02-10 | 2013-05-08 | F. Hoffmann-La Roche AG | Detection of parvovirus B19 |
| AU2011253599B2 (en) * | 2004-09-30 | 2013-12-12 | Gen-Probe Incorporated | Assay for detecting and quantifying HIV-1 |
| CA2929741A1 (en) | 2004-09-30 | 2006-04-13 | Gen-Probe Incorporated | Assay for detecting and quantifying hiv-1 |
| US7833716B2 (en) * | 2006-06-06 | 2010-11-16 | Gen-Probe Incorporated | Tagged oligonucleotides and their use in nucleic acid amplification methods |
| WO2008080029A2 (en) | 2006-12-21 | 2008-07-03 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| WO2010105275A2 (en) | 2009-03-13 | 2010-09-16 | Cornell University | Method to assess human allograft status from microrna expression levels |
| EP2449132B1 (en) | 2009-07-01 | 2015-05-13 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| US9746479B2 (en) | 2010-03-09 | 2017-08-29 | Cornell University | Methods and compositions to predict and detect acute rejection |
| WO2014018885A2 (en) | 2012-07-27 | 2014-01-30 | Gen-Probe Incorporated | Dual reference calibration method and system for quantifying polynucleotides |
| KR101377824B1 (ko) * | 2012-11-19 | 2014-04-01 | 가톨릭대학교 산학협력단 | 수인성 바이러스 검출용 프라이머 및 이를 포함하는 검출 키트 |
| CN103901000B (zh) * | 2012-12-26 | 2016-09-28 | 江南大学 | 一种基于荧光共振能量转移检测伏马菌毒素b1的方法 |
| US9758828B2 (en) | 2013-01-31 | 2017-09-12 | Cornell University | Methods to detect, treat and prevent acute cellular rejection in kidney allografts |
| US9982301B2 (en) | 2014-01-07 | 2018-05-29 | Cornell University | Urine mRNA profile and acute dysfunction of kidney allograft |
| EP4560026A3 (en) | 2014-04-10 | 2025-08-27 | The Trustees of the University of Pennsylvania | Use of micro-ribonucleic acid (mirna) to diagnose transplant rejection and tolerance of immunosuppression therapy |
| US11339436B2 (en) | 2015-02-03 | 2022-05-24 | The Trustees Of The University Of Pennsylvania | Methods for early identification of bone healing ability in injured patients |
| US10370731B2 (en) | 2016-06-10 | 2019-08-06 | Roche Molecular Systems, Inc. | Compositions and methods for detection of hepatitis C virus genotype 3 |
| CN110699353A (zh) * | 2019-07-26 | 2020-01-17 | 安徽大学 | 一种靶向端粒的核酸探针 |
| CN120265769A (zh) * | 2023-10-08 | 2025-07-04 | 迈克生物股份有限公司 | 引物探针组合物、核酸检测方法及应用 |
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| US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US6007983A (en) * | 1995-12-22 | 1999-12-28 | Visible Genetics Inc. | Method and kit for evaluation of HIV mutations |
| DE69738687D1 (de) * | 1996-04-12 | 2008-06-26 | Phri Properties Inc | Sonden, kits und assays |
| US6117635A (en) | 1996-07-16 | 2000-09-12 | Intergen Company | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
| US6037130A (en) * | 1998-07-28 | 2000-03-14 | The Public Health Institute Of The City Of New York, Inc. | Wavelength-shifting probes and primers and their use in assays and kits |
| AU3438999A (en) | 1999-05-07 | 2000-11-21 | Nationales Zentrum Fur Retroviren | Detection system for human immunodeficiency virus based on nucleic acid amplification |
| US6759193B2 (en) * | 1999-07-28 | 2004-07-06 | The Government Of The Republic Of Singapore | Detection of human hepatitis B virus surface antigen mutants by specific amplification and its application on gene chip |
| AU2002307359B2 (en) * | 2001-04-17 | 2007-09-13 | The New York Blood Center, Inc. | Universal multi-variant detection system |
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2002
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- 2002-04-17 CN CNB028102681A patent/CN1279182C/zh not_active Expired - Fee Related
- 2002-04-17 ES ES02762133T patent/ES2278043T3/es not_active Expired - Lifetime
- 2002-04-17 AT AT02762133T patent/ATE346958T1/de not_active IP Right Cessation
- 2002-04-17 US US10/399,843 patent/US7348164B2/en not_active Expired - Lifetime
- 2002-04-17 JP JP2002582264A patent/JP4271944B2/ja not_active Expired - Fee Related
- 2002-04-17 CA CA002444174A patent/CA2444174A1/en not_active Abandoned
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- 2002-04-17 EP EP02762133A patent/EP1390544B1/en not_active Expired - Lifetime
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2012
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2013
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Also Published As
| Publication number | Publication date |
|---|---|
| US7348164B2 (en) | 2008-03-25 |
| CN1279182C (zh) | 2006-10-11 |
| CN1509338A (zh) | 2004-06-30 |
| JP2004532027A (ja) | 2004-10-21 |
| ATE346958T1 (de) | 2006-12-15 |
| US20120258446A1 (en) | 2012-10-11 |
| ES2278043T3 (es) | 2007-08-01 |
| US8192939B2 (en) | 2012-06-05 |
| EP1390544A2 (en) | 2004-02-25 |
| CA2444174A1 (en) | 2002-10-24 |
| US20130288231A1 (en) | 2013-10-31 |
| US20110053138A1 (en) | 2011-03-03 |
| JP4271944B2 (ja) | 2009-06-03 |
| DE60216445T2 (de) | 2007-10-31 |
| DE60216445D1 (de) | 2007-01-11 |
| EP1390544A4 (en) | 2004-07-14 |
| HK1065825A1 (zh) | 2005-03-04 |
| EP1390544B1 (en) | 2006-11-29 |
| AU2002307359B2 (en) | 2007-09-13 |
| KR20040018354A (ko) | 2004-03-03 |
| WO2002083927A3 (en) | 2003-03-20 |
| US20040053284A1 (en) | 2004-03-18 |
| WO2002083927A2 (en) | 2002-10-24 |
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