KR20040017051A - A process for producing a composition presenting an effect of moxacautery and pharmaceutically acceptable preparations using the same - Google Patents

Abstract

PURPOSE: Provided are a method for producing a composition of Artemisia vulgaris L. having moxibustion effect and pharmaceutically acceptable preparations using the same. The composition is used as a raw material of high functional foods or cosmetics. CONSTITUTION: A method for producing composition of Artemisia vulgaris L. having moxibustion effect comprises the steps of: cutting Artemisia vulgaris L. and/or medicinal herbs and pulverizing them; heating the powder at 700-1000 deg.C in a vessel until the temperature inside the vessel becomes 300-400 deg.C to give a solution; spraying 10-30 wt.% of vinegar to the solution then cooling them; adding the mixture of alcohol and water in a mixing ratio of 7:3 to the vinegar added solution; precipitating or centrifuging, and freeze-drying them to give extract powder; heating Artemisia vulgaris L. and/or medicinal herbs by until their color becomes yellow or brown; adding the mixture of alcohol and water in a mixing ratio of 7:3 to the roasting product; precipitating or centrifuging them, followed by freeze-drying to give extract powder; and mixing the extract powder prepared above together with pharmaceutically acceptable medicinal herb powder.

Description

A method for preparing moxa moth herbal composition having moxibustion effect and a pharmaceutically acceptable formulation using the same {A PROCESS FOR PRODUCING A COMPOSITION PRESENTING AN EFFECT OF MOXACAUTERY AND PHARMACEUTICALLY ACCEPTABLE PREPARATIONS USING THE SAME}

The present invention relates to a method for producing a moxa moxibustion herbal composition having a moxibustion effect and a pharmaceutically acceptable formulation using the same. More specifically, the moxibustion effect comprising the active ingredient extracted by heat processing mugwort or mugwort and herbal medicine It relates to a method for producing a moxa moth herbal composition having a and a patch, a sheet and a pressing agent using the composition.

Moxibustion, one of the representative treatments of oriental medicine, is a method of using heat generated by burning wormwood by burning wormwood.

Conventional moxibustion is a combination of mugwort or mugwort and herbal medicine, the efficacy of moxibustion does not depend solely on the stimulation caused by the heat generated during combustion, and the active ingredient released from mugwort or the compounded herbal medicine penetrates the affected or acupuncture skin It is a way to show the therapeutic effect.

However, despite its efficacy due to environmental pollution, burns, and scars caused by smoke generated from burning wormwood, they have been avoided by the general public.

In some advanced technologies related to such moxibustion, the moxibustion effect is applied to the skin by applying extracts or lotions containing active ingredients of mugwort and herbal medicine without heat processing and applying it to the skin and applying heat transfer. It was.

As moxibustion is a smoking effect only when burning cigarettes, the moxibustion is sedated by the chemical changes in heat and active ingredients produced by burning mugwort and herbal medicines.

Conventional moxibustion moxibustion moxibustion is avoided by the general public due to environmental pollution caused by smoke, burns and scars due to overheating, and despite its efficacy, it has been difficult to popularize. Extracts of wormwood and herbal medicines suggested as alternatives In addition, the present invention has been made to solve the weak effect.

The object of the present invention is to burn moxa and other herbs, heating on the skin to infiltrate the active ingredient into the skin to break away from the conventional method of treating diseases by heating the mugwort with a single ingredient or two or more herbs and active ingredients It is to provide a method for producing a moxa moth herbal composition having a moxibustion effect of extracting and the main component thereof.

In addition, an object of the present invention is to provide a form of a patch, a sheet or a pressing agent so that anyone can easily contact the excellent efficacy of moxibustion using moxibustion easily and safely.

1 is a cross-sectional view of a patch containing the mugwort moist herbal composition according to the present invention attached to the skin,

FIG. 2 is a plan view of the patch shown in FIG. 1,

3 is a cross-sectional view of the sheet agent containing the mugwort moist herbal composition according to the present invention attached to the skin,

4 is a plan view of a sheet made in FIG. 3,

Figure 5 is a plan view of another embodiment of the sheet containing the moxa moth herbal composition according to the invention,

Figure 6 is a cross-sectional view of the pressure-sensitive adhesive containing the mugwort moxa herbal composition according to the present invention attached to the skin,

Fig. 7 is a plan view of the push rod shown in Fig. 6.

<Description of Major Symbols in Drawing>

1 --- Mugwort Herbal Medicine Composition 1-1 --- Absorbent

2 --- skin 3 --- heating element pad

4 --- Adhesive Cloth 5 --- Porous Adhesive Cloth

6 --- Sheet 7 --- Insulating Film

8 --- Pressure

Hereinafter, the present invention will be described in detail.

The present invention is to cut or powder the mugwort and / or herbal medicine to a certain size into a non-ferrous metal container or pottery, cover the lid formed with a communication connection, and then slowly heated to 700 to 1000 ℃ while stirring, the internal temperature is about 300 to 400 When the temperature reaches 0 ° C, turn off the fire to obtain the herbal liquid supercarbonate, and then spray it with about 10 to 30% by weight of vinegar based on the total weight of the carbonaceous water, and then cool it. The mixed solvent was added about 5 times by weight to the carbonaceous material, and then precipitated by stirring, or centrifuged and lyophilized to prepare a carbonaceous herbal extract powder; After the mugwort and / or herbal medicines are heat-processed by the ultra-sulfur method or the ultra-ultraviolet method, the solvent mixed with alcohol and water at 7: 3 is added to the weight ratio of the medicine by stirring about 5 times and then precipitated or centrifuged. Freeze-dried powdered to prepare a sulfur / vinegar herbal extract powder; The method of producing a moxibustion herbal medicine composition having a moxibustion effect, characterized in that it is prepared by adding the above-described carbonaceous herbal medicine extract powder as a main component, and the sulfur / vinegar herbal medicine extract powder as an auxiliary component and adding a pharmaceutically acceptable herbal medicine powder. will be.

Hereinafter, the present invention will be described in more detail.

1. Preparation of main ingredients

The composition according to the present invention uses the mugwort as a single component or by combining the herbal medicine having a synergistic effect with mugwort and heat processing to use it as a main component.

Pharmacologically, mugwort is known to be used in a wide range of diseases, such as stomach, liver, heart, kidney and warm up the body to increase the history of the disease.

Herbal medicines that can be used with wormwood in the present invention, for example, garlic, preferably dried garlic, dried ginger is the health (乾薑). Garlic is a plant that has a warming property and is widely used for food and medicine, and is a representative food of the US Cancer Institute's anti-cancer food. In addition, health is a warming and detoxification, cold and cold limbs, abdominal colds, lung diseases, colds, etc. used to improve appetite, inhibit intestinal abnormal fermentation, promote gas excretion, cerebral cortex excitement, improve blood circulation, It is known to have an antiperspirant action.

In the present invention, when using mugwort and herbal medicine at the same time, the ratio of mugwort: dry garlic: health is preferably in a weight ratio of 7: 2: 1, but the amount used is mugwort as a main ingredient, but other ingredients may be arbitrarily added or subtracted. .

The mugwort or Chinese herbal medicine is used by heat processing, the materials are first cut into a suitable size or powdered into a non-ferrous metal container or pottery and covered with a lid formed in a portion connected to the communication and heated to 700 to 1000 ℃ while slowly stirring. When the internal temperature reaches about 300 to 400 ° C, a large amount of smoke that decomposes mugwort and medicinal hemicellulose, and a light yellowish brown smoke mixed with a large amount of moisture are generated. In order to increase the penetration and effect of the active ingredient in (iii), the vinegar is sprayed with about 10 to 30% by weight based on the total weight of the carbonaceous material and cooled.

The ingredients extracted and processed as described above are similar to those of high quality wood vinegar, and some active ingredients of mugwort and herbal medicines and acidic liquid main ingredients of pH 3 are fatty acids such as formic acid and propionic acid, and alcohols such as methanol and prophenol. It is composed of more than 200 ingredients such as acetone and formaldehyde, and it is an effective herbal medicine that corresponds to wood vinegar which cannot be synthesized artificially, such as blood or sea water.

Next, in order to extract the water-soluble component and the fat-soluble component to the maximum, about 5 times the weight ratio of the supercarbon water was mixed with the solvent obtained by mixing alcohol: water (7: 3) with the herbal liquid supercarbon water prepared above. Precipitate, or centrifuge to freeze-dry powder to use as the main ingredient of the product for moxibustion. It is preferable to use ethanol for alcohol for extraction of super carbon water.

In addition, the moisture and smoke generated until the coal briquettes contain the scents of essential oils and various active ingredients, thereby cooling the smoke discharged through the communication connected to the lid to recover the extract.

In the above-described process, the herbal herbal supercarb is recovered in an amount of 2 to 3% by weight of the injected material, and the herbal herbal extract freeze-dried powder obtained by extracting the herbal herb is extracted in a weight ratio with respect to the herbal herbal supercarb.

The freeze-dried powder and extract of the obtained carbonaceous herb extract is used as a main component of the mugwort moist herbal composition according to the present invention.

2. Preparation of auxiliary ingredients

In order to improve the function of nutrition and weakness of the product according to the present invention, the above-mentioned ingredients, namely, mugwort, garlic, health, etc., are subjected to the sulfur and vinegar methods using the herbal medicine of the herbal medicine to extract the active ingredient and as an auxiliary ingredient Mix and process moxibustion products.

1) ultra-sulfur method (炒 黃 法): a weak fire, that is, a method of roasting yellowing by heating to 450 to 600 ℃, the weakness of the change is small, but the active ingredient is easily eluted and the penetration is enhanced, the drug efficacy is enhanced. The purpose of the emulsification method is to enhance the therapeutic effect of the medicinal herbs, to reduce the weakness and to reduce the toxicity, and to destroy the enzyme components can sustain the preservation of the components. Herbal remedy is reduced by about 20%.

2) Ultra-choco (약 法): Method of heating the medicine to medium fire, that is, from 600 to 700 ℃ until the surface turns black, the intermediate between the sulfur and peat that changes the weakness of some components and preserves the internal components Form. The purpose of performing the edgy method is to facilitate weak elution, increase penetration, reduce weakness, reduce toxicity, and facilitate preservation. Herbal medicines reduce about 40% of essential oils and change the composition, for example:

-Hydrolysis of alkaloids

-Inhibition of Glycosides by Heating Law

-Activation of essential oil's therapeutic action

-Convergence, detoxification

-Destruction of organic acid and enhanced water solubility

-Solubility in water and bioactivity increases due to changes in fat content, resin, and protein decomposition

The medicinal herbs subjected to the above-mentioned sulfuric acid method or ultra-ultraviolet method are obtained by extracting an aqueous alcohol solution mixed at a ratio of 7: 3 by weight with a solvent to make an extract concentrated to 10% by volume and then freeze-dried powder.

3. heating agent

In order to apply the heat effect of moxibustion such as when burning wormwood, the heating element is made in the form of a sheet and manufactured and packaged in a double structure on the patch or sheet.

One example of a heating composition usable in the present invention is described below;

ingredient Content (for 100% by weight of total weight)

40 to 45 weight percent iron

Sodium chloride 6-10 wt%

4-5 wt% sodium peroxide

Silica gel 30-40 wt%

Licorice 5 to 10% by weight

In addition, another example of a heater composition usable in the present invention is described below;

ingredient Content (for 100% by weight of total weight)

50 to 60 wt% iron

Sodium chloride 3-5 weight%

Activated carbon granules 10-15% by weight

20-30% by weight of water

In the above heating composition, the activated carbon granules are less polluted than the fine powder, and the heat can be maintained at 40 to 60 ° C. for 6 to 8 hours by infiltrating water into the heat generating fabric during use.

Porous breathable packaging materials such as cotton cloth, paper cloth, and non-woven fabrics, in which both sides are packed in an appropriate amount and size, or a vinyl or resin film containing aluminum powder or copper powder is used for one side to increase thermal insulation.

4. Absorbent

When the dried moxibustion herb composition having the moxibustion effect of the present invention is completely dried, the powder is removed, and the powder is removed to a non-woven fabric and adhered closely to the affected area or acupuncture points. In this case, the absorption detoxifying agent absorbs the substance accompanying the congestion or inflammatory state with water to decompose and detoxify it.

Absorbent compositions usable in the present invention are described below;

ingredient Content (for 100% by weight of total weight)

Wormwood vinegar powder 20 wt%

Licorice powder 10% by weight

20% by weight

Ocher 25% by weight

Dextrin 20 wt%

Salt 5 wt%

Moxa moth herbal composition having a moxibustion effect according to the present invention can be prepared in the form of a patch by mixing the warning agent, it can be prepared in the form of a sheet containing the absorbent detoxifying agent component, or can be prepared in a pressure-sensitive formulation by mold pressing. .

Hereinafter, with reference to the accompanying drawings will be described a pharmaceutically acceptable formulation containing the moxa moth herbal composition having a moxibustion effect according to the present invention.

As shown in Figure 1 and Figure 2, the composition and the warning agent (1) prepared in accordance with the present invention on a cotton cloth, non-woven fabric or a synthetic film to a thickness of 2 to 3 mm after drying the bottom surface to facilitate separation The coated release paper can be pasted, and a heat generating pad 3 containing a heating agent can be attached to the back side, and then a patch can be prepared by attaching an adhesive cloth 4 and / or a porous adhesive cloth 5. The patch prepared as described above has a heating effect because iron is oxidized by air introduced through the adhesive cloth 4 or the porous adhesive cloth 5 when attached to the skin 2 to produce heat. 1) will promote penetration into the skin.

In addition, as shown in Figures 3 to 5, the sheet agent is used to mix the wormwood herb solution composition (1) and the absorbent detoxifying agent (1-1), respectively, or combine them separately. As shown in FIG. 4, the moxa moth herbal composition (1) and the absorbent detoxifying agent (1-1) are mixed and injected into a bag made of cotton cloth, paper cloth, nonwoven fabric, etc., sealed or coated, and separately include a heating agent. The heat generating pad 3 is attached to the rear surface thereof, and then put into a sheet to prepare a sheet material.

Figure 5 shows another embodiment of the sheet according to the present invention, in order to increase the moxibustion effect by injecting the moxibustion herb solution composition (1) in the center of the three quartered side by dividing the side of the sheet in three parts and absorbed on both sides Inject and seal the antidote (1-1). A heating pad 3 coated with a heating agent is attached to the back side of the absorbent detoxifying agent 1-1, that is, the surface which does not touch the skin, and the insulating film 7 is attached to the back of the heating pad 3, and then the adhesive cloth ( 4) is pasted and put into the sheet 6 and packaged to produce a sheet. Thus prepared sheet according to the present invention can be obtained at the same time the effect of detoxification and moxibustion because the iron of the heating agent is oxidized by the moisture containing the waste material emitted from the skin to generate the heat of oxidation to show the heating effect. The sheet agent according to the present invention can be arbitrarily prepared in the shape of a circle, an oval, a rectangle, or the like.

Figures 6 and 7 shows a pushpin according to the present invention, the mugwort moth herbal composition (1) prepared above was put into a mold and pressurized to produce a tack (건조) form and then dried, in the shape of a pushpin It is prepared by attaching a release paper to the push bar (8) surface with a pointed needle and attaching an adhesive cloth (4) to the bottom surface without a needle. In use, remove the release paper from the pressing agent and attach the adhesive cloth 4 to the affected area or acupuncture points so that the pressing rod presses the skin 2 so that the pointed tip presses the skin to give a stimulus like saliva. It can be released, dissolved in 3 to 4 hours by water gradually absorbed from the skin, the active ingredient is eluted, at the same time absorbed into the skin by osmotic pressure can exhibit the same efficacy as moxibustion without actually burning.

Hereinafter, the present invention will be described in more detail with reference to the following Examples.

Example 1 Preparation of Patch

A warning mixture consisting of 20 g of zinc oxide, 25 g of castor oil, 100 g of pineapple and / or 20 g of beeswax and a small amount of vegetable oil was heated and agitated, and then liquefied evenly. After thoroughly mixing the total weight of the following medicines and the warning agent in a ratio of 1: 9 by weight, it was applied to a cotton cloth, nonwoven fabric or synthetic resin film with a thickness of 2 to 3 mm and dried. After drying, the front side was attached to a release paper treated with a base for easy separation, and the rear side was attached to a heat generating sheet containing a heating agent composition, and then airtightly wrapped with a porous adhesive cloth to absorb the air to oxidize iron.

ingredient Content (weight, g)

Colostrum Herbal Extract Powder10

Herbal / Herbal Herb Extract Powder10

Garlic Powder10

Health powder 5

Liquorice Powder 5

Ginseng Powder 5

Chili Powder 5

Gastric Acid Powder10

Sulfur 5

Mint Brain 5

Dragon Brain 5

* The powder in the above means a freeze-dried powder or dry powder.

Components of the Heater Composition Content (weight, g)

Iron 45

Sodium Chloride 10

Sodium peroxide 5

Silica Gel 30

Licorice 10

Example 2 Preparation of Patch

Except that the heating agent composition was used as follows, a patch containing a mugwort moxa herb composition having a moxa effect was prepared in the same manner as in Example 1.

ingredient Content (weight, g)

Iron 60

Sodium chloride 5

Activated Carbon Granules 15

Water 20

Example 3 Production of Sheet

Raw material A and raw material B were prepared by mixing each of the following, and raw material A and raw material B were respectively injected into the bag made of nonwoven fabric, and the injection port was sealed to prepare raw material A bag and raw material B bag. A sheet material was prepared by adding and packing a raw material A bag, a raw material B bag, and a heating pad containing the heating agent according to Example 1 having a heat insulating film formed on the back in a separately prepared sheet. The prepared sheet was used by attaching the surface with the raw material A to the skin and attaching the adhesive cloth on the back.

Raw material ingredient for moxibustion effect (raw material A) Content (weight, g)

Colostrum Herbal Extract Powder10

Herbal / Herbal Herb Extract Powder10

Garlic Powder10

Health powder 5

Gardenia Powder 5

Safflower powder 5

Ginseng Powder 5

Chili Powder 3

Bamboo salt 5

Peppermint 1

Dragon Brain 1

Dextrin 10

Miso Powder25

* The powder in the above means a freeze-dried powder or dry powder.

Absorption detoxifier ingredient (raw material B) Content (weight, g)

Wormwood Pellets Powder 20

Licorice Powder 10

Confession 20

Ocher 25

Dextrin 20

Saline 5

The material absorbs about 50% by weight in the weight ratio of the absorbing detoxifying agent after 6-8 hours after attaching to the menstrual blood or the affected area with strong absorption power, and the absorption rate is very high in the normal site, not the affected area such as bleeding, inflammation or congestion of the sole of the foot. Found to be low.

Example 4 Preparation of Press Release

As described below, each component was mixed, introduced into a mold, pressurized, manufactured in a tack form, and dried. The obtained tack-like mixture was attached to the adhesive cloth, and the back surface adhered to the skin was then attached with release paper, cut into appropriate sizes, and hermetically wrapped in a plastic bag or the like.

ingredient Content (weight, g)

Colostrum Herbal Extract Powder10

Supercarb herbal extract 30

Herbal / Herbal Herb Extract Powder10

Chili Powder 5

Gardenia Powder 5

Safflower powder 5

Bamboo salt 5

Citric Acid 5

Dextrin 25

The present invention is easy and convenient to use the mugwort moxa herbal composition with a moxibustion effect of the active ingredient by heating the mugwort as a single ingredient or two or more herbal medicines and the main ingredient as a patch, sheet or pressing agent You can safely take advantage of the excellent efficacy of moxibustion.

The patch, sheet or pressurizing agent containing the moxa moth herbal composition having the moxibustion effect prepared in the method of the present invention is a double structure including a heating element pad using an oxidative heat of iron and a push rod capable of applying stimulation such as saliva. By allowing the active ingredient to penetrate and heat the affected skin and heating at the same time, anyone can easily and safely get the moxibustion effect.

The present invention is to popularize our global traditional moxibustion therapy as well as globalization, the moxa moth herbal composition prepared according to the method of the present invention can be used as a raw material of high functional food or cosmetics.

Claims (8)

After cutting or powdering mugwort and / or herbal medicines to a certain size and placing them in a non-ferrous metal container or pottery, the lid is formed with a communication connection, and then heated to 700 to 1000 ° C. with gentle stirring, and the internal temperature reaches about 300 to 400 ° C. Turn off the fire to obtain a herbal liquor supercarbonate, spray about 10-30% by weight of vinegar to the total weight of the supercarbonate, and then cool and mix the alcohol: water in this herbal liquor at 7: 3. About 5 times the weight of the solvent was added to the carbonaceous material, and then precipitated by stirring or centrifuged, and then freeze-dried powdered to prepare the carbonaceous herbal extract powder; After the mugwort and / or herbal medicines are heat-processed by the ultra-sulfur method or the ultra-ultraviolet method, the solvent mixed with alcohol and water at 7: 3 is added to the weight ratio of the medicine by stirring about 5 times and then precipitated or centrifuged. Freeze-dried powdered to prepare a sulfur / vinegar herbal extract powder; A method of producing a moxibustion herbal medicine composition having a moxibustion effect, characterized in that it is prepared by adding the above-described carbonaceous herb extract powder as a main ingredient, and adding sulfuric acid / chocho herb extract powder as an auxiliary ingredient and a pharmaceutically acceptable herbal medicine powder. The method of claim 1, wherein the herbal medicine is dried garlic and / or dried ginger method of producing a moxa moth herbal composition having a moxa effect. According to claim 1, The main ingredient is moxa moxa herbal composition having a moxibustion effect, characterized in that the extract made by cooling the smoke discharged through the communication connected to the lid of the container of the carbonaceous herbal liquid extract powder and the coal charcoal Manufacturing method. The method of producing a mugwort herb solution composition according to any one of claims 1 to 3, wherein the use ratio of mugwort: dried garlic: health is 7: 2: 1 by weight. Release paper coated with a bottom surface for easy separation after applying the dried moxa moth herbal composition prepared according to any one of claims 1 to 4 on a cotton cloth, nonwoven fabric or synthetic film with a thickness of 2 to 3 mm. On the back, a heating agent composed of 40 to 45% by weight of iron, 6 to 10% by weight of sodium chloride, 4 to 5% by weight of sodium peroxide, 30 to 40% by weight of silica gel, and 5 to 10% by weight of licorice, based on the total weight of the heating agent. The patch is prepared by attaching a heating element pad containing a sticking adhesive. The patch according to claim 5, wherein the heating agent comprises 50 to 60% by weight of iron, 3 to 5% by weight of sodium chloride, 10 to 15% by weight of activated carbon granules, and 20 to 30% by weight of water, based on the total weight of the heating agent. My. The mugwort herb solution composition according to any one of claims 1 to 4 is mixed with or separated from the absorption detoxifying agent component as described below, or the mixture is injected into a sheet, or a double surface of the mugwort herbal medicine composition is prepared. A sheet agent, which is prepared by injecting and sealing by injecting the following absorption detoxifying agent component into the rear surface. Absorption antidote ingredients Content (for 100% by weight of total weight) Wormwood Pellets Powder20 Licorice Powder10 Confessions 20 Yellow soil 25 Dextrin 20 Saline 5 The mugwort moth herbal composition prepared according to any one of claims 1 to 4 is put into a mold, pressurized, prepared in the form of a tack and dried, and the paste is prepared by attaching a release paper. Absorbent.