KR20040004445A - 프로테아제 억제제 - Google Patents

프로테아제 억제제 Download PDF

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Publication number
KR20040004445A
KR20040004445A KR10-2003-7006807A KR20037006807A KR20040004445A KR 20040004445 A KR20040004445 A KR 20040004445A KR 20037006807 A KR20037006807 A KR 20037006807A KR 20040004445 A KR20040004445 A KR 20040004445A
Authority
KR
South Korea
Prior art keywords
alkyl
substituted
methyl
group
benzofuran
Prior art date
Application number
KR10-2003-7006807A
Other languages
English (en)
Korean (ko)
Inventor
데니스 에스. 야마시따
다니엘 에프. 베버
로버트 더블유. 마르퀴스
Original Assignee
스미스클라인 비참 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스미스클라인 비참 코포레이션 filed Critical 스미스클라인 비참 코포레이션
Publication of KR20040004445A publication Critical patent/KR20040004445A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
KR10-2003-7006807A 2000-11-22 2001-11-19 프로테아제 억제제 KR20040004445A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25250800P 2000-11-22 2000-11-22
US60/252,508 2000-11-22
PCT/US2001/051647 WO2003053331A2 (en) 2000-11-22 2001-11-19 Protease inhibitors

Publications (1)

Publication Number Publication Date
KR20040004445A true KR20040004445A (ko) 2004-01-13

Family

ID=22956303

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2003-7006807A KR20040004445A (ko) 2000-11-22 2001-11-19 프로테아제 억제제

Country Status (17)

Country Link
EP (1) EP1392657A4 (es)
JP (1) JP2005513083A (es)
KR (1) KR20040004445A (es)
CN (1) CN1635903A (es)
AR (1) AR034278A1 (es)
AU (1) AU2001298052A1 (es)
BR (1) BR0115473A (es)
CA (1) CA2436850A1 (es)
CZ (1) CZ20031403A3 (es)
HU (1) HUP0301964A3 (es)
IL (1) IL155997A0 (es)
MX (1) MXPA03004542A (es)
NO (1) NO20032328L (es)
PL (1) PL366232A1 (es)
UY (1) UY27032A1 (es)
WO (1) WO2003053331A2 (es)
ZA (1) ZA200303848B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030144175A1 (en) 1998-12-23 2003-07-31 Smithkline Beecham Corporation Protease inhibitors
US7071184B2 (en) 2000-03-21 2006-07-04 Smithkline Beecham Corporation Protease inhibitors
AU2001268407A1 (en) * 2000-06-14 2001-12-24 Smithkline Beecham Corporation Protease inhibitors
JPWO2008149971A1 (ja) 2007-06-08 2010-08-26 日本ケミファ株式会社 脳動脈瘤の治療または予防薬
JPWO2009054454A1 (ja) 2007-10-24 2011-03-03 国立大学法人 東京医科歯科大学 カテプシン阻害剤を有効成分として含有するＴｏｌｌ様受容体のシグナル伝達の調整剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200101869T2 (tr) * 1998-12-23 2002-01-21 Smithkline Beecham Corporation Proteaz İnhibitörleri.
US7071184B2 (en) * 2000-03-21 2006-07-04 Smithkline Beecham Corporation Protease inhibitors
AU2001268407A1 (en) * 2000-06-14 2001-12-24 Smithkline Beecham Corporation Protease inhibitors

Also Published As

Publication number Publication date
AR034278A1 (es) 2004-02-18
UY27032A1 (es) 2002-07-31
CZ20031403A3 (cs) 2003-10-15
IL155997A0 (en) 2003-12-23
JP2005513083A (ja) 2005-05-12
MXPA03004542A (es) 2003-09-10
AU2001298052A1 (en) 2003-07-09
NO20032328L (no) 2003-07-02
PL366232A1 (en) 2005-01-24
WO2003053331A2 (en) 2003-07-03
ZA200303848B (en) 2004-06-28
NO20032328D0 (no) 2003-05-22
HUP0301964A2 (en) 2007-02-28
CN1635903A (zh) 2005-07-06
EP1392657A4 (en) 2004-03-10
HUP0301964A3 (en) 2007-09-28
EP1392657A2 (en) 2004-03-03
CA2436850A1 (en) 2003-07-03
WO2003053331A3 (en) 2003-11-13
BR0115473A (pt) 2004-09-28

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Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid