KR20030060771A - 국소용 마취제/아편양약물 제제 및 이들의 용도 - Google Patents
국소용 마취제/아편양약물 제제 및 이들의 용도 Download PDFInfo
- Publication number
- KR20030060771A KR20030060771A KR1020027014500A KR20027014500A KR20030060771A KR 20030060771 A KR20030060771 A KR 20030060771A KR 1020027014500 A KR1020027014500 A KR 1020027014500A KR 20027014500 A KR20027014500 A KR 20027014500A KR 20030060771 A KR20030060771 A KR 20030060771A
- Authority
- KR
- South Korea
- Prior art keywords
- morphine
- administered
- topical
- pharmaceutical composition
- dosage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20043700P | 2000-04-28 | 2000-04-28 | |
| US60/200,437 | 2000-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20030060771A true KR20030060771A (ko) | 2003-07-16 |
Family
ID=22741721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020027014500A Ceased KR20030060771A (ko) | 2000-04-28 | 2001-04-27 | 국소용 마취제/아편양약물 제제 및 이들의 용도 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6825203B2 (enExample) |
| EP (1) | EP1276475A2 (enExample) |
| JP (1) | JP2004512260A (enExample) |
| KR (1) | KR20030060771A (enExample) |
| AU (1) | AU2001257326A1 (enExample) |
| CA (1) | CA2407683C (enExample) |
| IL (1) | IL152473A0 (enExample) |
| WO (1) | WO2001082914A2 (enExample) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1309562A (zh) * | 1998-07-16 | 2001-08-22 | 纪念斯隆-凯特林癌症中心 | 包括一种阿片样物质镇痛剂和一种nmda拮抗剂的局部给药组合物 |
| EP2359688B1 (en) | 1999-03-23 | 2015-05-27 | Hibernation Therapeutics, a KF LLC | Organ arrest, protection and preservation |
| ATE491474T1 (de) * | 2001-06-07 | 2011-01-15 | Sang Christine Dr | Behandlung von neuropathischen schmerzen mittels eines n-methyl-d-aspartate (nmda)-rezeptor- antagonists |
| DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| GB0121980D0 (en) | 2001-09-11 | 2001-10-31 | Cathnet Science Holding As | Expandable stent |
| JP2003081872A (ja) * | 2001-09-13 | 2003-03-19 | Nippon Oruganon Kk | 掻痒治療薬 |
| US7351255B2 (en) | 2001-12-03 | 2008-04-01 | Xtent, Inc. | Stent delivery apparatus and method |
| US7137993B2 (en) | 2001-12-03 | 2006-11-21 | Xtent, Inc. | Apparatus and methods for delivery of multiple distributed stents |
| US7309350B2 (en) | 2001-12-03 | 2007-12-18 | Xtent, Inc. | Apparatus and methods for deployment of vascular prostheses |
| US7182779B2 (en) | 2001-12-03 | 2007-02-27 | Xtent, Inc. | Apparatus and methods for positioning prostheses for deployment from a catheter |
| US7294146B2 (en) | 2001-12-03 | 2007-11-13 | Xtent, Inc. | Apparatus and methods for delivery of variable length stents |
| US20040186551A1 (en) | 2003-01-17 | 2004-09-23 | Xtent, Inc. | Multiple independent nested stent structures and methods for their preparation and deployment |
| US20030135266A1 (en) | 2001-12-03 | 2003-07-17 | Xtent, Inc. | Apparatus and methods for delivery of multiple distributed stents |
| US7892273B2 (en) | 2001-12-03 | 2011-02-22 | Xtent, Inc. | Custom length stent apparatus |
| US7147656B2 (en) | 2001-12-03 | 2006-12-12 | Xtent, Inc. | Apparatus and methods for delivery of braided prostheses |
| ES2397574T3 (es) | 2002-07-30 | 2013-03-08 | Omeros Corporation | Procedimiento y soluciones de irrigación oftalmológica |
| US7273889B2 (en) * | 2002-09-25 | 2007-09-25 | Innovative Drug Delivery Systems, Inc. | NMDA receptor antagonist formulation with reduced neurotoxicity |
| US20060034941A1 (en) * | 2002-12-23 | 2006-02-16 | Global Cardiac Solutions Pty Ltd | Organ preconditioning, arrest, protection, preservation and recovery |
| US7241308B2 (en) | 2003-06-09 | 2007-07-10 | Xtent, Inc. | Stent deployment systems and methods |
| US7326236B2 (en) | 2003-12-23 | 2008-02-05 | Xtent, Inc. | Devices and methods for controlling and indicating the length of an interventional element |
| US7323006B2 (en) | 2004-03-30 | 2008-01-29 | Xtent, Inc. | Rapid exchange interventional devices and methods |
| US20050265219A1 (en) * | 2004-05-11 | 2005-12-01 | Texas Instruments Incorporated | Orthogonal frequency division multiplex (OFDM) packet detect unit, method of detecting an OFDM packet and OFDM receiver employing the same |
| EP1595541A1 (en) * | 2004-05-12 | 2005-11-16 | Alcasynn Pharmaceuticals Gmbh | Use of opioid receptor antagonist compounds for the prevention and/or treatment of diseases associated with the target calcineurin |
| US7666914B2 (en) | 2004-06-03 | 2010-02-23 | Richlin David M | Topical preparation and method for transdermal delivery and localization of therapeutic agents |
| US8317859B2 (en) | 2004-06-28 | 2012-11-27 | J.W. Medical Systems Ltd. | Devices and methods for controlling expandable prostheses during deployment |
| US20050288766A1 (en) | 2004-06-28 | 2005-12-29 | Xtent, Inc. | Devices and methods for controlling expandable prostheses during deployment |
| AU2005319578A1 (en) * | 2004-11-24 | 2006-06-29 | Neopro Labs, Llc | Methods and compositions for treating conditions |
| EP1702627A1 (en) * | 2005-03-18 | 2006-09-20 | Laboratorios Del Dr. Esteve, S.A. | Analgesic combination of sodium channel blockers with opioid antagonists |
| WO2007025249A2 (en) * | 2005-08-26 | 2007-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for treatment of headaches by administration of oxytocin |
| US20070093517A1 (en) * | 2005-10-24 | 2007-04-26 | Gary Newton | Local anesthetic compositions |
| US7695733B2 (en) | 2006-02-17 | 2010-04-13 | Zasler Nathan D | Application of topical anesthetics for modulation of neurogenic tremor |
| CA2646885A1 (en) | 2006-03-20 | 2007-09-27 | Xtent, Inc. | Apparatus and methods for deployment of linked prosthetic segments |
| JP2009538834A (ja) | 2006-05-29 | 2009-11-12 | ハイバーネイション セラピューティクス リミテッド | 組織維持の改善 |
| CA2692256C (en) | 2006-07-25 | 2017-01-10 | Hibernation Therapeutics Limited | Trauma therapy |
| TW200815004A (en) * | 2006-09-19 | 2008-04-01 | Chi Mei Foundation Hospital | Local anesthetic composition containing dextrorotatory morphinan derivative or pharmaceutically acceptable salts thereof |
| US20080220062A1 (en) * | 2006-10-23 | 2008-09-11 | Psivida, Inc. | Sustained release of agents for localized pain management |
| EP2117521B1 (en) | 2006-11-03 | 2012-06-27 | Durect Corporation | Transdermal delivery systems comprising bupivacaine |
| US20080199510A1 (en) | 2007-02-20 | 2008-08-21 | Xtent, Inc. | Thermo-mechanically controlled implants and methods of use |
| CA2717162A1 (en) | 2007-03-02 | 2008-09-12 | Hibernation Therapeutics Limited | Transplants |
| US8486132B2 (en) | 2007-03-22 | 2013-07-16 | J.W. Medical Systems Ltd. | Devices and methods for controlling expandable prostheses during deployment |
| EP2152725A1 (en) | 2007-05-17 | 2010-02-17 | Neopro Labs, LLC | Crystalline and amorphous forms of peptide |
| US20090036541A1 (en) * | 2007-08-02 | 2009-02-05 | Donald David Mardis | Applicator and chemical combination for better topical anesthesia |
| JP5392089B2 (ja) * | 2007-11-14 | 2014-01-22 | 三菱瓦斯化学株式会社 | 皮膚の乾癬予防または改善剤 |
| US9101503B2 (en) | 2008-03-06 | 2015-08-11 | J.W. Medical Systems Ltd. | Apparatus having variable strut length and methods of use |
| GB0808751D0 (en) * | 2008-05-14 | 2008-06-18 | Serentis Ltd | Topical compositions of opioid compound for use in wound healing |
| US8828071B2 (en) | 2008-09-25 | 2014-09-09 | Advanced Bifurcation Systems, Inc. | Methods and systems for ostial stenting of a bifurcation |
| US12076258B2 (en) | 2008-09-25 | 2024-09-03 | Advanced Bifurcation Systems Inc. | Selective stent crimping |
| CA2739007C (en) | 2008-09-25 | 2017-10-31 | Advanced Bifurcation Systems Inc. | Partially crimped stent |
| US11298252B2 (en) | 2008-09-25 | 2022-04-12 | Advanced Bifurcation Systems Inc. | Stent alignment during treatment of a bifurcation |
| US8821562B2 (en) | 2008-09-25 | 2014-09-02 | Advanced Bifurcation Systems, Inc. | Partially crimped stent |
| US12324756B2 (en) | 2008-09-25 | 2025-06-10 | Advanced Bifurcation Systems Inc. | System and methods for treating a bifurcation |
| US8808347B2 (en) | 2008-09-25 | 2014-08-19 | Advanced Bifurcation Systems, Inc. | Stent alignment during treatment of a bifurcation |
| AU2011232362B2 (en) | 2010-03-24 | 2015-12-10 | Advanced Bifurcation Systems Inc. | System and methods for treating a bifurcation |
| WO2011119882A1 (en) | 2010-03-24 | 2011-09-29 | Advanced Bifurcation Systems, Inc | Methods and systems for treating a bifurcation with provisional side branch stenting |
| CA2826760A1 (en) | 2011-02-08 | 2012-08-16 | Advanced Bifurcation Systems, Inc. | Multi-stent and multi-balloon apparatus for treating bifurcations and methods of use |
| EP3777780B1 (en) | 2011-02-08 | 2024-04-24 | Advanced Bifurcation Systems Inc. | System for treating a bifurcation with a fully crimped stent |
| SMT201700010T1 (it) | 2011-04-29 | 2017-03-08 | Moberg Pharma Ab | Composizioni farmaceutiche comprendenti un anestetico locale come bupivacaina per somministrazione locale alla bocca o alla gola |
| US11786455B2 (en) | 2011-05-10 | 2023-10-17 | Itochu Chemical Frontier Corporation | Non-aqueous patch |
| ES3034911T3 (en) | 2011-05-10 | 2025-08-26 | Itochu Chemical Frontier Corp | Non-aqueous patch |
| MX368747B (es) | 2011-05-10 | 2019-10-14 | Itochu Chemical Frontier Corp | Parche no acuoso de lidocaína y un agente de disolución que comprende un ácido orgánico y un polialcohol que están contenidos en un emplaste para usarse en el tratamiento de dolor muscular a través de la piel. |
| HUE039266T2 (hu) | 2011-09-27 | 2018-12-28 | Itochu Chemical Frontier Corp | Nem-vizes tapasz |
| AU2013201465B2 (en) | 2012-10-24 | 2016-03-03 | Rayner Intraocular Lenses Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
| BR112016000804A2 (pt) | 2013-07-17 | 2017-08-22 | Hibernation Therapeuitics A Kf Llc | Método para tratar hemorragia, choque e lesão cerebral |
| TWI705812B (zh) | 2014-12-01 | 2020-10-01 | 奥默羅斯公司 | 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液 |
| SG11201705591PA (en) | 2015-01-07 | 2017-08-30 | Trigemina Inc | Magnesium-containing oxytocin formulations and methods of use |
| HRP20250215T1 (hr) | 2016-04-12 | 2025-06-20 | Tonix Pharma Limited | Formulacije oksitocina koje sadrže magnezij i postupci upotrebe |
| US11160799B2 (en) | 2019-10-22 | 2021-11-02 | Cessatech A/S | Pediatric combination |
| JP2023511370A (ja) | 2020-01-22 | 2023-03-17 | シーロス セラピューティクス, インコーポレイテッド | Nmda拮抗薬の副作用の低減 |
| CN114373519A (zh) * | 2021-12-31 | 2022-04-19 | 苏州佩德生物医药有限公司 | 一种trpv3抑制剂的虚拟筛选方法、药物先导化合物及应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4446140A (en) | 1981-12-10 | 1984-05-01 | Nelson Research & Development Company | Method and composition for treating mouth pain |
| US4626539A (en) | 1984-08-10 | 1986-12-02 | E. I. Dupont De Nemours And Company | Trandermal delivery of opioids |
| DE4223004A1 (de) | 1992-07-13 | 1994-01-20 | Liedtke Pharmed Gmbh | Einzeldosierte halbfeste topische Arzneiform zur Transdermaltherapie |
| WO1994014427A2 (en) | 1992-12-23 | 1994-07-07 | Zymogenetics, Inc. | Use of skyrin and analogues for the treatment of diabetes mellitus and process for their preparation |
| US5321012A (en) | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
| US5523323A (en) | 1993-09-14 | 1996-06-04 | Maccecchini; Maria-Luisa | Use of partial agonists of the NMDA receptor to reduce opiate induced tolerance and dependence |
| US5635204A (en) | 1994-03-04 | 1997-06-03 | Montefiore Medical Center | Method for transdermal induction of anesthesia, analgesia or sedation |
| US5589480A (en) | 1994-08-17 | 1996-12-31 | Elkhoury; George F. | Topical application of opioid analgesic drugs such as morphine |
| KR960019204A (ko) | 1994-11-01 | 1996-06-17 | 이헌조 | 씨디-롬, 플로피디스크겸용 드라이브 및 구동방법 |
| US5866143A (en) | 1995-03-24 | 1999-02-02 | El Khoury And Stein, Ltd. | Topical application of opioid drugs such as morphine for relief of itching and skin disease |
| US5948389A (en) * | 1995-06-07 | 1999-09-07 | El Khoury & Stein, Ltd. | Method of enhancing the analgesic efficacy of locally and topically administered opioids and other local anesthetics |
| US5840731A (en) | 1995-08-02 | 1998-11-24 | Virginia Commonwealth University | Pain-alleviating drug composition and method for alleviating pain |
| US6197830B1 (en) | 1995-09-22 | 2001-03-06 | Bruce M. Frome | Method for achieving relief from sympathetically mediated pain |
| CA2266556C (en) | 1996-09-30 | 2007-11-06 | Hoechst Marion Roussel, Inc. | Nmda (n-methyl-d-aspartate) antagonists |
| JP2001506652A (ja) | 1996-12-16 | 2001-05-22 | アルコン ラボラトリーズ,インコーポレイテッド | 眼の痛みを治療するためのκオピオイド・アゴニストの局所使用 |
| EP1003494B1 (en) | 1997-01-22 | 2007-03-21 | Cornell Research Foundation, Inc. | (d)-METHADONE, A NONOPIOID ANALGESIC |
| US5834480A (en) | 1997-06-13 | 1998-11-10 | Elkhoury; George F. | Topical application of opioids for treatment of acne and sebaceous gland disorders |
| CN1309562A (zh) * | 1998-07-16 | 2001-08-22 | 纪念斯隆-凯特林癌症中心 | 包括一种阿片样物质镇痛剂和一种nmda拮抗剂的局部给药组合物 |
| JP2000169378A (ja) * | 1998-12-10 | 2000-06-20 | Taisho Pharmaceut Co Ltd | 咽頭疾患用組成物 |
| US6383511B1 (en) * | 1999-10-25 | 2002-05-07 | Epicept Corporation | Local prevention or amelioration of pain from surgically closed wounds |
-
2001
- 2001-04-27 US US09/844,111 patent/US6825203B2/en not_active Expired - Lifetime
- 2001-04-27 EP EP01930827A patent/EP1276475A2/en not_active Withdrawn
- 2001-04-27 CA CA2407683A patent/CA2407683C/en not_active Expired - Fee Related
- 2001-04-27 JP JP2001579789A patent/JP2004512260A/ja not_active Abandoned
- 2001-04-27 KR KR1020027014500A patent/KR20030060771A/ko not_active Ceased
- 2001-04-27 IL IL15247301A patent/IL152473A0/xx unknown
- 2001-04-27 WO PCT/US2001/013546 patent/WO2001082914A2/en not_active Ceased
- 2001-04-27 AU AU2001257326A patent/AU2001257326A1/en not_active Abandoned
- 2001-10-11 US US09/975,812 patent/US6790855B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2407683A1 (en) | 2001-11-08 |
| US6790855B2 (en) | 2004-09-14 |
| AU2001257326A1 (en) | 2001-11-12 |
| US20020052319A1 (en) | 2002-05-02 |
| US20020004484A1 (en) | 2002-01-10 |
| WO2001082914A2 (en) | 2001-11-08 |
| EP1276475A2 (en) | 2003-01-22 |
| CA2407683C (en) | 2010-04-13 |
| IL152473A0 (en) | 2003-05-29 |
| JP2004512260A (ja) | 2004-04-22 |
| US6825203B2 (en) | 2004-11-30 |
| WO2001082914A3 (en) | 2002-08-01 |
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