KR20020041348A - The production of Bio-Hormone Power advanced immunity - Google Patents

Abstract

PURPOSE: A process of preparing a bioregulator(referred to as biohormone power) by mixing an extract of green tea with natural material such as colostrum milk, pomegranate, silk amino acid and the like is provided which has low risk of side effects, improves immune function, and promotes blood circulation and metabolism of a human body. CONSTITUTION: A mixture of 20% by weight of a pomegranate extract, 15% by weight of colostrum milk, 10% by weight of a silk amino acid, 10% by weight of a green tea extract, 5% by weight of evergreen palmberry, 3% by weight of taurine, 2% by weight of octacosanol, 33% by weight of dried yeast, 0.97% by weight of fermented calcium lactate, 1% by weight of magnesium stearate and 0.03% by weight of vitamin A is uniformly blended in a mixer and then formed in the shape of a tablet.

Description

Production of Bio-Holmon Power with Enhanced Immune Function {The production of Bio-Hormone Power advanced immunity}

The present invention extracts the catechin component from carefully selected green tea leaves, and mixes natural substances such as colostrum, pomegranate, silk amino acid, evergreen palm barley, taurine, amino compound, and octacosanol in a certain ratio to greatly help the growth and maintenance of body tissue. It relates to a method for producing bio-holmon power, which enhances the metabolism and stamina by strengthening the immune system, as well as promoting the secretion of hormones and preventing the aging phenomenon.

Medically, immunity means the ability to overcome the germs that cause inflammation, injury, and disease, which means finding and neutralizing or eliminating a foreign object. The body continues to strive for homeostasis by interfering with harmful stimuli to the body. Immune defenses function in a variety of human reactions, such as producing specific antibodies against these stimulants. It fights against microbial invasion, provides resistance against infectious and infectious diseases, and also removes debris from the body.

Humans have a self-defense immune system, but as they age, their immune function weakens, leading to metabolic abnormalities and eventually disease. In addition, in modern times, physical and physical stress and fatigue are increased due to irregular lifestyles and rapidly changing environmental factors, which decreases immunity to the body and increases the probability of developing various infectious diseases.

Health supplements are extracted as is or food. It is a product manufactured by the method of purification and mixing. It is manufactured for the purpose of improving physical control functions to compensate for nutritional deficiencies and imbalances and to overcome the stimulus against external environmental factors.

ㆍ Since medicines and treatment methods are mainly developed for the treatment after the occurrence of a disease, food is developed and used to prevent disease. In order to prevent the deterioration of immunity and to enhance immunity, it is not enough to consume daily meals.

At present, there are various kinds of health foods related to immunity promotion, but they do not solve the side effects and fundamental problems, and the reliability of the products is falling.

Recently, health foods containing pomegranate and colostrum included in the present invention in the United States, Europe, Japan, etc. have been getting a good response to enhance immunity. In addition to pomegranate and colostrum, catechin, silk amino acid, evergreen palmvarie, taurine, octacosanol, aminocomplex and the like are contained, and the functional and effective aspects of each component of the present invention are described as follows.

Colostrum reported that all inflammation is orally invading the human body or parasitic on the mucosal surface, according to researchers at the University of Veterinary Pharmacy in the United States. It is known that immune factors, which play an important role in colostrum in the 1980s, do not enter the intestine and the intestinal wall, bronchus, etc., but are present there. It can help to boost immunity of all ages from elderly to elderly.

Pomegranate is a plant and contains sex hormones that act on human life and has been widely used to maintain health, prevent aging, and alleviate symptoms such as disease and wounds. It is also an fruit that can be used for anemia, recovery from illness, nutritional support for healthy people, and physical fitness enhancement.

Catechin, a green tea extract, has an antioxidant action to remove heavy metals and remove free radicals. Antioxidant effect is to inhibit the mutation of the cells, incapacitate carcinogens and can prevent the cancer and various detoxification effects. In addition, catechin is a component that helps to boost immunity, decrease blood cholesterol, and high blood pressure.

Silk amino acid helps fatigue, improve stamina, improve immunity, and hangover. It is effective in preventing arteriosclerosis and hypertension by inhibiting blood cholesterol, and it can help to improve dependent diabetes and suppress blood sugar rise. .

Octacosanol is effective in improving durability, energy and stamina, improves resistance to the effects of stress, and promotes sex hormone secretion.

Taurine prevents hypertension, keeps blood pressure normal, and is effective in lowering cholesterol. It is also found in breast milk and is an essential nutrient for children's growth. It is necessary for the development of children's nerves and brain.

Therefore, the present invention does not use any chemical synthetic raw materials and has been studied to enhance immune function without the risk of side effects. By adding unique functional raw materials such as colostrum, pomegranate, green tea extract, silk amino acid, etc. It is to provide supplementary health supplement foods.

The present invention also provides natural products and extracts containing the bioactive components. It is made from raw materials such as natural-derived ingredients, and it will be useful to those who want to receive relief from intake, help to improve immunity, prevent aging, and improve physical strength.

Figure 1 is a block diagram showing the manufacturing process of the present invention, immune-promoting food.

Figure 2 is a graph of the degree of nitric oxide production by silk amino acids (acid hydrolysates).

Confirmation experiments for enhancing the immunity of silk amino acids added to the present invention will be described in detail below.

Exploration of Macrophage Enhancing Active Peptides from Silk Amino Acids

[Research Method]

① Culture of Mouse Intraperitoneal Macrophage

4 ml of 1% thioglycollate was injected intraperitoneally into the Balb / c mice, and after 4 days, the mice were sacrificed by cervical dislocation, and 10 ml of RPMI 1640 medium was injected into the abdominal cavity. Inner macrophage cells were collected. The intraperitoneal cells were suspended in RPMI 1640 with 10% fetal calf serum and 200 on 96-well plate. Each was busy. The number of cells per well is 2 10 ⁵ was incubated at 37 ° C. in 5% CO ₂ . After 2 hours, the cells that did not adhere to the plate were removed and the attached macrophages continued to be cultured. Acid hydrolyzate samples were filtered sterilized and then added at various concentrations. Interferon- after about 12-16 hours Activated macrophages by adding, and after about 24 hours, a portion of the culture was taken to measure the amount of nitric oxide generated during the culture. Positive control group lipolysaccharide (LPS) 1 Treated at a concentration of

② production measurement of reactive nitrogen species

The amount of reactive nitrogen species generated in macrophage was determined by quantifying the amount of nitrite accumulated in activated macrophage culture. The nitric oxide produced by the activation of macrophage is oxidized to nitrogen dioxide, which is then further oxidized to nitrite and nitrate and accumulates in the culture.

Nitrite occupies most of the accumulated oxides and is easily quantified by pink color reaction with Griess reagent (0.05% naphthylethyenediamine dihydrochloride, 0.5% sulfanilamide, 2.5% H ₃ PO ₄ ). 50 μl of the macrophage culture supernatant was transferred to another 96-well plate and mixed with the same amount of Griess reagent. After 10 minutes, the absorbance at 550 nm was measured using an ELISA reader. Sodium nitrite was used as a standard.

[Results]

The hydrolysis of fibroin acid and each enzymatic hydrolyzate at 1 mg / ml and 5 mg / ml in the macrophage culture resulted in very high nitric oxide production in the case of acid hydrolyzate. Although nitric oxide production was promoted, it was much less than acid hydrolyzate. When the acid hydrolyzate was treated in a more specific concentration range, it was found that the amount of nitric oxide increased clearly with the treatment concentration (Fig. 2).

In order to achieve the above object, the following describes the preparation method of tablets containing functional materials, such as pomegranate, colostrum, catechin, silk amino acid, evergreen palm barrier, taurine, octacosanol, aminocomplex and the like.

First step: raw material inspection

Check that the raw materials used in the product meet the specifications. (Moisture measurement, appearance, heavy metal, E. coli test)

Second Process: Raw Material Blending

Only raw materials that meet the specifications are carefully selected and weighed and blended according to the ingredients and blending ratios in Table 1.

Third process: mixing

Use a mixer to ensure that each raw material is mixed evenly.

4th process: molding

The raw material uniformly mixed through the delivery nozzle is compressed into a molding machine. At this time, the weight of tableting shall be 400 mg.

5th Process: Packing

Packing standard (400mg 120 tablets, 400 mg 300 tablets).

6th Process: Product Inspection

Inspect the product to ensure it is manufactured to specifications and free of contamination during the manufacturing process.

TABLE 1 Ingredients and Blending Ratio (Unit Weight%)

In addition, the daily intake of the present invention is ingested in drinking water on an empty stomach in the morning and evening, two tablets of 400mg each.

Humans have a self-defense immune system, but as they age, their immune function weakens, leading to metabolic abnormalities and eventually disease.

The present invention extracts physiologically functional ingredients from natural products without using chemical synthetic raw materials to reduce the risk of side effects, improves immune function and protects the human body from various harmful enzymes, which is effective for promoting metabolism and nutritional supply of the human body. There is.

In addition, the present invention can help a lot of middle-aged people who want to maintain health, strengthen stamina, improve stamina, prevent disease and aging, and also for growth and brain rotation, growth and maintenance of children and adolescent students It works. It is also rich in female hormone estrogen, which is effective in preventing osteoporosis and treating menopausal disorders in menopausal women.

Therefore, the present invention, first, to enhance or activate the immune function of the human body to facilitate metabolism, and second, to promote the hormone secretion has the function to prevent and reverse the aging phenomenon. Third, it strengthens physical strength and strengthens eyesight and memory.

Claims (1)

20% pomegranate extract, colostrum 15%, silk amino acid 10%, green tea extract 10%, evergreen palm bari 5%, taurine 3%, octacosanol 2%, dry yeast 33%, fermented calcium lactate 0.97%, magnesium stearate 1%, Method for producing bio-holmon power with enhanced immune function, characterized in that 0.03% of vitamin A is weighed and uniformly mixed in a mixer, and then molded into a tablet form of 400 mg weight.