KR20010074429A - 섬유 교체 단백질을 함유하는 변형된 아데노바이러스 - Google Patents
섬유 교체 단백질을 함유하는 변형된 아데노바이러스 Download PDFInfo
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- KR20010074429A KR20010074429A KR1020007008959A KR20007008959A KR20010074429A KR 20010074429 A KR20010074429 A KR 20010074429A KR 1020007008959 A KR1020007008959 A KR 1020007008959A KR 20007008959 A KR20007008959 A KR 20007008959A KR 20010074429 A KR20010074429 A KR 20010074429A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
- C12N2810/859—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from immunoglobulins
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Applications Claiming Priority (3)
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| US7484498P | 1998-02-17 | 1998-02-17 | |
| US60/074,844 | 1998-02-17 | ||
| PCT/US1999/003233 WO1999041359A1 (en) | 1998-02-17 | 1999-02-16 | Modified adenovirus containing a fiber replacement protein |
Publications (1)
| Publication Number | Publication Date |
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| KR20010074429A true KR20010074429A (ko) | 2001-08-04 |
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| KR1020007008959A Withdrawn KR20010074429A (ko) | 1998-02-17 | 1999-02-16 | 섬유 교체 단백질을 함유하는 변형된 아데노바이러스 |
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| US (1) | US6210946B1 (https=) |
| EP (1) | EP1070118B1 (https=) |
| JP (1) | JP2002503459A (https=) |
| KR (1) | KR20010074429A (https=) |
| CN (1) | CN1297479A (https=) |
| AT (1) | ATE342350T1 (https=) |
| AU (1) | AU751542B2 (https=) |
| BR (1) | BR9908018A (https=) |
| CA (1) | CA2321135A1 (https=) |
| DE (1) | DE69933550T2 (https=) |
| IL (1) | IL137730A0 (https=) |
| NO (1) | NO20004563L (https=) |
| NZ (1) | NZ506451A (https=) |
| WO (1) | WO1999041359A1 (https=) |
| ZA (1) | ZA200004208B (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US6815200B1 (en) * | 1998-02-17 | 2004-11-09 | The Uab Research Foundation | Modified adenovirus containing a fiber replacement protein |
| US20050095231A1 (en) * | 1998-02-17 | 2005-05-05 | Curiel David T. | Modified adenovirus containing a fiber replacement protein |
| AU4070499A (en) | 1998-04-30 | 1999-11-16 | Cornell Research Foundation Inc. | Adenoviral vectors with tandem fiber proteins |
| EP1112372A1 (en) | 1998-09-11 | 2001-07-04 | Genvec, Inc. | Alternatively targeted adenovirus |
| US6649396B1 (en) * | 1999-02-05 | 2003-11-18 | Uab Research Foundation | Fiber receptor-independent system for the propagation of adenoviral vectors |
| CA2378324A1 (en) * | 1999-07-06 | 2001-01-11 | Leif Lindholm | Recombinant adenovirus |
| AU2001252766A1 (en) * | 2000-04-26 | 2001-11-07 | Crucell Holland B.V. | Adenovirus vectors with knobless fibers, and their uses |
| US7332337B2 (en) * | 2000-05-16 | 2008-02-19 | Galapagos Nv | Viral vectors having tissue tropism for T-lymphocytes, B- and mast cells |
| JP3635462B2 (ja) * | 2000-05-31 | 2005-04-06 | 国立医薬品食品衛生研究所長 | アデノウイルスベクター |
| JP2003534805A (ja) | 2000-05-31 | 2003-11-25 | ユニバーシティ オブ サスカチュワン | 変化した親和性を有する改変ウシアデノウイルス |
| GB0017720D0 (en) | 2000-07-19 | 2000-09-06 | Got A Gene Ab | Modified virus |
| ES2375557T3 (es) | 2001-06-22 | 2012-03-02 | The Trustees Of The University Of Pennsylvania | Adenovirus recombinantes que comprenden prote�?nas de adenovirus de simios y usos de los mismos. |
| US6905678B2 (en) * | 2001-07-07 | 2005-06-14 | Crucell Holland B.V. | Gene delivery vectors with cell type specificity for mesenchymal stem cells |
| WO2003062400A2 (en) * | 2002-01-24 | 2003-07-31 | The Scripps Research Institute | Fiber shaft modifications for efficient targeting |
| US20050003548A1 (en) * | 2002-07-22 | 2005-01-06 | Nikolay Korokhov | Targeted adenoviral vector displaying immunoglobulin-binding domain and uses thereof |
| AU2003252118A1 (en) * | 2002-07-22 | 2004-02-09 | Emd Lexigen Research Center | Targeted adenoviral vector displaying immunoglobulin-binding domain and uses thereof |
| AU2003259199A1 (en) * | 2002-07-22 | 2004-02-09 | Vectorlogics, Inc. | Adenoviral vector incorporating zipper peptide-modified fiber protein and uses thereof |
| US7611868B2 (en) | 2003-05-14 | 2009-11-03 | Instituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Recombinant modified adenovirus fiber protein |
| JP2007531507A (ja) * | 2003-06-11 | 2007-11-08 | ザ スクリップス リサーチ インスティテュート | 効率的な受容体結合のための修飾型線維タンパク質 |
| US7291498B2 (en) | 2003-06-20 | 2007-11-06 | The Trustees Of The University Of Pennsylvania | Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses |
| KR20180122043A (ko) | 2010-06-10 | 2018-11-09 | 유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 | 데스모글레인 2(디에스쥐2)와 아데노바이러스의 상호작용을 위한 방법 및 시스템 |
| AU2014236207B2 (en) | 2013-03-14 | 2019-05-23 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
| EP3132038A4 (en) | 2014-04-18 | 2017-11-29 | Washington University | Adenoviral targeting, compositions and methods therefor |
| KR20250081944A (ko) | 2014-09-24 | 2025-06-05 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양 살상 바이러스 및 이의 사용방법 |
| JP7264592B2 (ja) * | 2015-01-26 | 2023-04-25 | ザ ユニバーシティー オブ シカゴ | ＩＬ１３Ｒα２結合剤及び癌治療におけるその使用 |
| EP4155411A1 (en) | 2016-02-23 | 2023-03-29 | Salk Institute for Biological Studies | Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics |
| WO2017147265A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| EP3532082A4 (en) | 2016-12-12 | 2020-08-26 | Salk Institute for Biological Studies | SYNTHETIC ADENOVIRUS TUMOR TARGETING AND THEIR USES |
| EP3565578A1 (en) | 2016-12-21 | 2019-11-13 | Memgen LLC | Armed replication-competent oncolytic adenoviruses |
| MX2020010499A (es) | 2018-04-09 | 2020-10-28 | Salk Inst For Biological Studi | Composiciones de adenovirus oncoliticas con propiedades aumentadas de replicacion. |
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| GB9223084D0 (en) * | 1992-11-04 | 1992-12-16 | Imp Cancer Res Tech | Compounds to target cells |
| US5543328A (en) * | 1993-08-13 | 1996-08-06 | Genetic Therapy, Inc. | Adenoviruses having modified fiber proteins |
| US5559099A (en) * | 1994-09-08 | 1996-09-24 | Genvec, Inc. | Penton base protein and methods of using same |
| US5846782A (en) * | 1995-11-28 | 1998-12-08 | Genvec, Inc. | Targeting adenovirus with use of constrained peptide motifs |
| US5770442A (en) * | 1995-02-21 | 1998-06-23 | Cornell Research Foundation, Inc. | Chimeric adenoviral fiber protein and methods of using same |
| EP0866721A4 (en) * | 1995-12-08 | 2003-06-04 | Univ Alabama Birmingham Res Fo | TARGET ADENOVIRAL VECTORS |
| US5877011A (en) * | 1996-11-20 | 1999-03-02 | Genzyme Corporation | Chimeric adenoviral vectors |
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1999
- 1999-02-16 IL IL13773098A patent/IL137730A0/xx unknown
- 1999-02-16 AT AT99932506T patent/ATE342350T1/de not_active IP Right Cessation
- 1999-02-16 WO PCT/US1999/003233 patent/WO1999041359A1/en not_active Ceased
- 1999-02-16 EP EP99932506A patent/EP1070118B1/en not_active Expired - Lifetime
- 1999-02-16 BR BR9908018-4A patent/BR9908018A/pt not_active IP Right Cessation
- 1999-02-16 DE DE69933550T patent/DE69933550T2/de not_active Expired - Lifetime
- 1999-02-16 CA CA002321135A patent/CA2321135A1/en not_active Abandoned
- 1999-02-16 US US09/250,580 patent/US6210946B1/en not_active Expired - Lifetime
- 1999-02-16 JP JP2000531540A patent/JP2002503459A/ja active Pending
- 1999-02-16 KR KR1020007008959A patent/KR20010074429A/ko not_active Withdrawn
- 1999-02-16 CN CN99805041A patent/CN1297479A/zh active Pending
- 1999-02-16 NZ NZ506451A patent/NZ506451A/xx unknown
- 1999-02-16 AU AU32940/99A patent/AU751542B2/en not_active Ceased
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2000
- 2000-08-17 ZA ZA200004208A patent/ZA200004208B/en unknown
- 2000-09-13 NO NO20004563A patent/NO20004563L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL137730A0 (en) | 2001-10-31 |
| ZA200004208B (en) | 2002-01-30 |
| US6210946B1 (en) | 2001-04-03 |
| NZ506451A (en) | 2003-06-30 |
| AU3294099A (en) | 1999-08-30 |
| NO20004563D0 (no) | 2000-09-13 |
| DE69933550D1 (de) | 2006-11-23 |
| EP1070118B1 (en) | 2006-10-11 |
| ATE342350T1 (de) | 2006-11-15 |
| EP1070118A1 (en) | 2001-01-24 |
| CN1297479A (zh) | 2001-05-30 |
| JP2002503459A (ja) | 2002-02-05 |
| BR9908018A (pt) | 2000-10-24 |
| AU751542B2 (en) | 2002-08-22 |
| EP1070118A4 (en) | 2003-05-02 |
| DE69933550T2 (de) | 2007-06-28 |
| CA2321135A1 (en) | 1999-08-19 |
| NO20004563L (no) | 2000-09-13 |
| WO1999041359A1 (en) | 1999-08-19 |
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