KR20000035893A - 분자 제제 광-활성화의 선택성 개선 방법 - Google Patents
분자 제제 광-활성화의 선택성 개선 방법 Download PDFInfo
- Publication number
- KR20000035893A KR20000035893A KR1019997001605A KR19997001605A KR20000035893A KR 20000035893 A KR20000035893 A KR 20000035893A KR 1019997001605 A KR1019997001605 A KR 1019997001605A KR 19997001605 A KR19997001605 A KR 19997001605A KR 20000035893 A KR20000035893 A KR 20000035893A
- Authority
- KR
- South Korea
- Prior art keywords
- coumarin
- photo
- tissue
- rhodamine
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/008—Two-Photon or Multi-Photon PDT, e.g. with upconverting dyes or photosensitisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00057—Light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8/739,801 | 1996-10-30 | ||
| US08/739,801 US5829448A (en) | 1996-10-30 | 1996-10-30 | Method for improved selectivity in photo-activation of molecular agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20000035893A true KR20000035893A (ko) | 2000-06-26 |
Family
ID=24973830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019997001605A Ceased KR20000035893A (ko) | 1996-10-30 | 1997-10-28 | 분자 제제 광-활성화의 선택성 개선 방법 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US5829448A (https=) |
| EP (1) | EP0977592A4 (https=) |
| JP (1) | JP2000511929A (https=) |
| KR (1) | KR20000035893A (https=) |
| CN (1) | CN1226148A (https=) |
| AU (1) | AU716507B2 (https=) |
| BR (1) | BR9712599A (https=) |
| CA (1) | CA2252783A1 (https=) |
| IL (1) | IL128355A (https=) |
| IN (1) | IN186854B (https=) |
| IS (1) | IS5006A (https=) |
| NO (1) | NO991492L (https=) |
| NZ (1) | NZ334190A (https=) |
| WO (1) | WO1998018399A1 (https=) |
Families Citing this family (138)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5912257A (en) | 1995-09-06 | 1999-06-15 | The Research Foundation Of State University Of New York | Two-photon upconverting dyes and applications |
| US7036516B1 (en) | 1996-10-30 | 2006-05-02 | Xantech Pharmaceuticals, Inc. | Treatment of pigmented tissues using optical energy |
| US7390668B2 (en) * | 1996-10-30 | 2008-06-24 | Provectus Pharmatech, Inc. | Intracorporeal medicaments for photodynamic treatment of disease |
| US6493570B1 (en) | 1998-11-02 | 2002-12-10 | Photogen, Inc. | Method for improved imaging and photodynamic therapy |
| US6331286B1 (en) * | 1998-12-21 | 2001-12-18 | Photogen, Inc. | Methods for high energy phototherapeutics |
| US6525862B2 (en) | 1996-10-30 | 2003-02-25 | Photogen, Inc. | Methods and apparatus for optical imaging |
| US20060095097A1 (en) * | 1996-10-30 | 2006-05-04 | Provectus Devicetech, Inc. | Treatment of pigmented tissue using optical energy |
| US7353829B1 (en) | 1996-10-30 | 2008-04-08 | Provectus Devicetech, Inc. | Methods and apparatus for multi-photon photo-activation of therapeutic agents |
| US5995867A (en) * | 1997-03-19 | 1999-11-30 | Lucid Inc | Cellular surgery utilizing confocal microscopy |
| US8974363B2 (en) | 1997-12-11 | 2015-03-10 | Provectus Pharmatech, Inc. | Topical medicaments and methods for photodynamic treatment of disease |
| WO1999054784A1 (en) | 1998-04-21 | 1999-10-28 | University Of Connecticut | Free-form nanofabrication using multi-photon excitation |
| US6223071B1 (en) | 1998-05-01 | 2001-04-24 | Dusa Pharmaceuticals Inc. | Illuminator for photodynamic therapy and diagnosis which produces substantially uniform intensity visible light |
| US8557298B2 (en) | 1998-08-06 | 2013-10-15 | Provectus Pharmatech, Inc. | Medicaments for chemotherapeutic treatment of disease |
| CN1132557C (zh) | 1998-08-06 | 2003-12-31 | 福托金公司 | 靶向局部治疗疾病的装置 |
| US20090117199A1 (en) * | 1998-08-06 | 2009-05-07 | Scott Timothy C | Method of treatment of cancer |
| US6986740B2 (en) * | 1998-11-02 | 2006-01-17 | Xantech Pharmaceuticals, Inc. | Ultrasound contrast using halogenated xanthenes |
| US9192780B2 (en) | 1998-11-30 | 2015-11-24 | L'oreal | Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders |
| US6283956B1 (en) * | 1998-11-30 | 2001-09-04 | David H. McDaniels | Reduction, elimination, or stimulation of hair growth |
| US20060212025A1 (en) | 1998-11-30 | 2006-09-21 | Light Bioscience, Llc | Method and apparatus for acne treatment |
| US6936044B2 (en) * | 1998-11-30 | 2005-08-30 | Light Bioscience, Llc | Method and apparatus for the stimulation of hair growth |
| US6887260B1 (en) | 1998-11-30 | 2005-05-03 | Light Bioscience, Llc | Method and apparatus for acne treatment |
| US8470296B2 (en) * | 1998-12-21 | 2013-06-25 | Provectus Pharmatech, Inc. | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
| US20020001567A1 (en) * | 1998-12-21 | 2002-01-03 | Photogen, Inc. | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
| US7384623B1 (en) | 1998-12-21 | 2008-06-10 | Provectus Pharmatech, Inc. | High energy phototherapeutic agents |
| US6454789B1 (en) | 1999-01-15 | 2002-09-24 | Light Science Corporation | Patient portable device for photodynamic therapy |
| JP2002534483A (ja) * | 1999-01-15 | 2002-10-15 | ライト サイエンシーズ コーポレイション | 代謝性骨障害または骨転移のための治療的組成物 |
| JP2002534218A (ja) * | 1999-01-15 | 2002-10-15 | ライト サイエンシーズ コーポレイション | 非侵襲性の脈管療法 |
| US6602274B1 (en) | 1999-01-15 | 2003-08-05 | Light Sciences Corporation | Targeted transcutaneous cancer therapy |
| EP1161924B1 (en) * | 1999-02-12 | 2006-12-20 | Alexei Ivanovich Trushin | Method for diagnosing proliferation regions and device for realising the same |
| WO2001006505A1 (en) * | 1999-07-15 | 2001-01-25 | Trid Store Ip, L.L.C. | Multilayer fluorescent optical disc with photosensitive fluorescent material |
| AU775373B2 (en) | 1999-10-01 | 2004-07-29 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| US7167615B1 (en) | 1999-11-05 | 2007-01-23 | Board Of Regents, The University Of Texas System | Resonant waveguide-grating filters and sensors and methods for making and using same |
| US6319273B1 (en) * | 1999-12-16 | 2001-11-20 | Light Sciences Corporation | Illuminating device for treating eye disease |
| US7897140B2 (en) | 1999-12-23 | 2011-03-01 | Health Research, Inc. | Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents |
| EP1267935A2 (en) * | 2000-01-12 | 2003-01-02 | Light Sciences Corporation | Novel treatment for eye disease |
| US7331350B2 (en) | 2000-02-11 | 2008-02-19 | The General Hospital Corporation | Photochemical tissue bonding |
| US7073510B2 (en) * | 2000-02-11 | 2006-07-11 | The General Hospital Corporation | Photochemical tissue bonding |
| US8215314B2 (en) * | 2000-02-11 | 2012-07-10 | The General Hospital Corporation | Photochemical tissue bonding |
| US7193706B2 (en) | 2000-08-02 | 2007-03-20 | Arizona Board Of Regents, Acting On Behalf Of Arizona State University | Computer interfaced scanning fluorescence lifetime microscope applied to directed evolution |
| JP4659300B2 (ja) * | 2000-09-13 | 2011-03-30 | 浜松ホトニクス株式会社 | レーザ加工方法及び半導体チップの製造方法 |
| AU2002245345A1 (en) | 2001-01-30 | 2002-08-12 | Board Of Trustees Operating Michigan State University | Control system and apparatus for use with laser excitation or ionization |
| US7567596B2 (en) * | 2001-01-30 | 2009-07-28 | Board Of Trustees Of Michigan State University | Control system and apparatus for use with ultra-fast laser |
| US7583710B2 (en) * | 2001-01-30 | 2009-09-01 | Board Of Trustees Operating Michigan State University | Laser and environmental monitoring system |
| US8208505B2 (en) * | 2001-01-30 | 2012-06-26 | Board Of Trustees Of Michigan State University | Laser system employing harmonic generation |
| US7609731B2 (en) * | 2001-01-30 | 2009-10-27 | Board Of Trustees Operating Michigan State University | Laser system using ultra-short laser pulses |
| US7973936B2 (en) * | 2001-01-30 | 2011-07-05 | Board Of Trustees Of Michigan State University | Control system and apparatus for use with ultra-fast laser |
| US7450618B2 (en) * | 2001-01-30 | 2008-11-11 | Board Of Trustees Operating Michigan State University | Laser system using ultrashort laser pulses |
| US6894161B2 (en) * | 2001-03-27 | 2005-05-17 | The University Of British Columbia | Methods and compositions for photo-cross linking photoactive compounds to target tissue |
| EP1372552B1 (de) * | 2001-03-27 | 2017-03-01 | WaveLight GmbH | Vorrichtung zur bearbeitung und diagnose von augengewebe |
| WO2002084271A2 (en) * | 2001-04-16 | 2002-10-24 | The Regents Of The University Of California | Methods and sensors for luminescent and optoelectronic detection and analysis of polynucleotides |
| US20030103995A1 (en) * | 2001-06-04 | 2003-06-05 | Hamblin Michael R. | Detection and therapy of vulnerable plaque with photodynamic compounds |
| EP1312353A1 (en) * | 2001-11-16 | 2003-05-21 | Ecole Polytechnique Federale De Lausanne (Epfl) | Method for hair removal |
| US7494502B2 (en) | 2002-02-11 | 2009-02-24 | Keraderm, Llc | Alteration of the skin and nail for the prevention and treatment of skin and nail infections |
| US6960201B2 (en) * | 2002-02-11 | 2005-11-01 | Quanticum, Llc | Method for the prevention and treatment of skin and nail infections |
| US20030191458A1 (en) * | 2002-04-03 | 2003-10-09 | Cornelius Diamond | Light-activated drug delivery method and device |
| EP1517684B1 (en) | 2002-06-27 | 2009-07-22 | Health Research, Inc. | Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy |
| WO2004005289A2 (en) | 2002-07-02 | 2004-01-15 | Health Research, Inc. | Efficient synthesis of pyropheophorbide a and its derivatives |
| US20040156743A1 (en) * | 2002-08-28 | 2004-08-12 | Eric Bornstein | Near infrared microbial elimination laser system |
| US8506979B2 (en) * | 2002-08-28 | 2013-08-13 | Nomir Medical Technologies, Inc. | Near-infrared electromagnetic modification of cellular steady-state membrane potentials |
| US20080131968A1 (en) * | 2002-08-28 | 2008-06-05 | Nomir Medical Technologies, Inc. | Near-infrared electromagnetic modification of cellular steady-state membrane potentials |
| US7713294B2 (en) | 2002-08-28 | 2010-05-11 | Nomir Medical Technologies, Inc. | Near infrared microbial elimination laser systems (NIMEL) |
| WO2004029690A1 (en) * | 2002-09-27 | 2004-04-08 | Saloma Caesar A | Two-color (two-photon) excitation with focused excitation beams and a raman shifter |
| EP2221810B1 (en) * | 2002-10-10 | 2014-09-24 | Landauer, Inc. | Method of erasing information stored on a luminescent data storage medium comprising aluminium oxide base material |
| KR20060041161A (ko) | 2003-04-10 | 2006-05-11 | 라이트 바이오사이언스, 엘엘씨 | 세포 증식 및 유전자 발현의 조절을 위한 광조절 방법 및광조절 장치 |
| AU2003292591A1 (en) * | 2003-06-20 | 2005-01-04 | Keio University | Photodynamic therapy apparatus, method for controlling photodynamic therapy apparatus, and photodynamic therapy method |
| EP1648385B1 (en) * | 2003-07-31 | 2016-05-04 | Gentlewaves Llc | System and method for the photodynamic treatment of skin |
| WO2005019800A2 (en) * | 2003-08-19 | 2005-03-03 | Cedars-Sinai Medical Center | Method for fluorescence lifetime imaging microscopy and spectroscopy |
| US20050053895A1 (en) | 2003-09-09 | 2005-03-10 | The Procter & Gamble Company Attention: Chief Patent Counsel | Illuminated electric toothbrushes emitting high luminous intensity toothbrush |
| US20050085455A1 (en) * | 2003-10-16 | 2005-04-21 | Light Sciences Corporation | Photodynamic therapy for local adipocyte reduction |
| WO2006015493A1 (en) * | 2004-08-13 | 2006-02-16 | Derma Laser Inc | Method for the treatment of mammalian skin tissues via pulse irradiation in the presence of a photoactive compound |
| JPWO2006049132A1 (ja) * | 2004-11-02 | 2008-05-29 | 学校法人慶應義塾 | 光線力学的治療装置 |
| CA2526327C (en) * | 2004-11-09 | 2014-01-07 | Institut National D'optique | Device for transmitting multiple optically-encoded stimulation signals to multiple cell locations |
| US7280078B2 (en) | 2004-11-20 | 2007-10-09 | Scenterra, Inc. | Sensor for detecting high frequency signals |
| EP1825560A4 (en) * | 2004-11-20 | 2010-09-15 | Kenneth E Salsman | DEVICE FOR EMISSION OF HIGH FREQUENCY SIGNALS |
| EP1851532A1 (en) * | 2005-02-14 | 2007-11-07 | Board of Trustees of Michigan State University | Ultra-fast laser system |
| WO2006128442A1 (de) * | 2005-05-31 | 2006-12-07 | W.O.M. World Of Medicine Ag | Verfahren und vorrichtung zur optischen charakterisierung von gewebe |
| CA2615799A1 (en) * | 2005-07-21 | 2007-02-01 | Nomir Medical Technologies, Inc. | Near infrared microbial elimination laser system (nimels) |
| US8618470B2 (en) | 2005-11-30 | 2013-12-31 | Board Of Trustees Of Michigan State University | Laser based identification of molecular characteristics |
| RU2314023C2 (ru) * | 2006-01-30 | 2008-01-10 | Михаил Витальевич Мошнин | Способ определения момента появления псораленов в коже пациента |
| US9018562B2 (en) * | 2006-04-10 | 2015-04-28 | Board Of Trustees Of Michigan State University | Laser material processing system |
| WO2007123518A1 (en) * | 2006-04-21 | 2007-11-01 | Cedars-Sinai Medical Center | Multiple imaging and/or spectroscopic modality probe |
| US20080275432A1 (en) * | 2006-05-11 | 2008-11-06 | Ceramoptec Industries, Inc. | Photodynamic foam composition and sclerosis treatment |
| CA2670711A1 (en) * | 2006-12-12 | 2008-06-19 | Nomir Medical Technologies, Inc. | Near-infrared electromagnetic modification of cellular steady-state membrane potentials |
| US20080208295A1 (en) * | 2007-02-28 | 2008-08-28 | Cumbie William E | Phototherapy Treatment and Device to Improve the Appearance of Nails and skin |
| US8951561B2 (en) * | 2007-08-06 | 2015-02-10 | Duke University | Methods and systems for treating cell proliferation disorders using plasmonics enhanced photospectral therapy (PEPST) and exciton-plasmon enhanced phototherapy (EPEP) |
| US8376013B2 (en) | 2008-03-11 | 2013-02-19 | Duke University | Plasmonic assisted systems and methods for interior energy-activation from an exterior source |
| AU2016210665B2 (en) * | 2007-04-08 | 2017-12-07 | Immunolight, Llc | Methods and systems for treating cell proliferation disorders |
| US9358292B2 (en) | 2007-04-08 | 2016-06-07 | Immunolight, Llc | Methods and systems for treating cell proliferation disorders |
| WO2015195896A1 (en) | 2014-06-19 | 2015-12-23 | Immunolight, Llc | Methods and systems for treating cell proliferation disorders with psoralen derivatives |
| US20140324138A1 (en) * | 2007-05-09 | 2014-10-30 | Massachusetts Institute Of Technology | Wirelessly-powered illumination of biological tissue |
| US20090104212A1 (en) * | 2007-08-06 | 2009-04-23 | Immunolight | Methods and systems for treating cell proliferation disorders using two-photon simultaneous absorption |
| WO2009038791A1 (en) | 2007-09-18 | 2009-03-26 | Applied Biosystems Inc. | Methods, systems and apparatus for light concentrating mechanisms |
| US20090156881A1 (en) * | 2007-10-15 | 2009-06-18 | Stokes John P | Convergent well irradiating plaque for choroidal melanoma |
| US8684898B2 (en) * | 2007-10-18 | 2014-04-01 | The Invention Science Fund I Llc | Ionizing-radiation-responsive compositions, methods, and systems |
| US9557635B2 (en) * | 2007-10-18 | 2017-01-31 | Gearbox, Llc | Ionizing-radiation-responsive compositions, methods, and systems |
| US8529426B2 (en) | 2007-10-18 | 2013-09-10 | The Invention Science Fund I Llc | Ionizing-radiation-responsive compositions, methods, and systems |
| US8168958B2 (en) * | 2007-10-18 | 2012-05-01 | The Invention Science Fund I, Llc | Ionizing-radiation-responsive compositions, methods, and systems |
| US20090104113A1 (en) * | 2007-10-18 | 2009-04-23 | Searete Llc | Ionizing-radiation-responsive compositions, methods, and systems |
| US8164074B2 (en) * | 2007-10-18 | 2012-04-24 | The Invention Science Fund I, Llc | Ionizing-radiation-responsive compositions, methods, and systems |
| US8227204B2 (en) * | 2007-10-18 | 2012-07-24 | The Invention Science Fund I, Llc | Ionizing-radiation-responsive compositions, methods, and systems |
| US9439897B2 (en) | 2007-11-06 | 2016-09-13 | Immunolight, Llc | Use of psoralen derivatives and combination therapy for treatment of cell proliferation disorders |
| US8311069B2 (en) | 2007-12-21 | 2012-11-13 | Board Of Trustees Of Michigan State University | Direct ultrashort laser system |
| DE102008011811B3 (de) * | 2008-02-29 | 2009-10-15 | Anton Dr. Kasenbacher | Dentales Laserbearbeitungsgerät zur Bearbeitung von Zahnmaterial |
| US9907976B2 (en) | 2011-07-08 | 2018-03-06 | Immunolight, Llc | Phosphors and scintillators for light stimulation within a medium |
| EP2268311A4 (en) | 2008-04-04 | 2014-08-27 | Immunolight Llc | NON-INVASIVE SYSTEMS AND IN SITU PHOTOBIOMODULATION METHODS |
| US8770203B2 (en) | 2008-07-14 | 2014-07-08 | Immunolight, Llc. | Advanced methods and systems for treating cell proliferation disorders |
| DE102009005194B4 (de) * | 2009-01-20 | 2016-09-08 | Anton Kasenbacher | Laserbearbeitungsgerät zur Bearbeitung eines Materials |
| EP2211430A3 (en) * | 2009-01-23 | 2015-05-27 | Board of Trustees of Michigan State University | Laser autocorrelation system |
| US8861075B2 (en) | 2009-03-05 | 2014-10-14 | Board Of Trustees Of Michigan State University | Laser amplification system |
| TWI511756B (zh) | 2009-04-21 | 2015-12-11 | 伊穆諾萊特公司 | 用以修飾介導生物活性或與生物活性有關之標靶結構之醫藥組合物或套組 |
| US20110054305A1 (en) * | 2009-08-30 | 2011-03-03 | Stephen Eliot Zweig | Photon upconverting implantable medical devices |
| US20110275686A1 (en) * | 2009-12-11 | 2011-11-10 | Biolitec, Inc. | Nanoparticle carrier systems based on poly(dl-lactic-co-glycolic acid) (plga) for photodynamic therapy (pdt) |
| US8630322B2 (en) * | 2010-03-01 | 2014-01-14 | Board Of Trustees Of Michigan State University | Laser system for output manipulation |
| US9642687B2 (en) | 2010-06-15 | 2017-05-09 | The Procter & Gamble Company | Methods for whitening teeth |
| US9095414B2 (en) * | 2011-06-24 | 2015-08-04 | The Regents Of The University Of California | Nonlinear optical photodynamic therapy (NLO-PDT) of the cornea |
| US9257206B2 (en) * | 2011-12-02 | 2016-02-09 | The Charles Stark Draper Laboratory, Inc. | Adiabatic rapid passage atomic beamsplitter using frequency-swept coherent laser beam pairs |
| US10549112B2 (en) | 2012-07-20 | 2020-02-04 | The General Hospital Corporation | Apparatus for tissue irradiation and methods and kits utilizing the same |
| WO2014015274A1 (en) | 2012-07-20 | 2014-01-23 | The General Hospital Corporation | Methods for tissue passivation |
| US20140140959A1 (en) | 2012-10-05 | 2014-05-22 | Aladar A. Szalay | Energy Absorbing-Based Diagnostic and Therapeutic Methods Employing Nucleic Acid Molecules Encoding Chromophore-Producing Enzymes |
| WO2014168734A1 (en) | 2013-03-15 | 2014-10-16 | Cedars-Sinai Medical Center | Time-resolved laser-induced fluorescence spectroscopy systems and uses thereof |
| EP2988693B1 (en) * | 2013-04-25 | 2019-06-12 | Koninklijke Philips N.V. | Non-invasive device for treatment of the skin using laser light |
| AU2014290513B2 (en) | 2013-07-18 | 2017-07-27 | The General Hospital Corporation | Vessel treatment systems, methods, and kits |
| WO2015108991A2 (en) | 2014-01-17 | 2015-07-23 | Imra America, Inc. | Laser-based modification of transparent materials |
| CA2947392C (en) | 2014-04-29 | 2022-11-01 | Theralase Technologies, Inc. | Apparatus and method for multiwavelength photodynamic therapy |
| US11534622B2 (en) | 2014-08-18 | 2022-12-27 | Immunolight, Llc | Non-invasive systems and methods for selective activation of photoreactive responses |
| EP3200575A1 (en) * | 2014-09-29 | 2017-08-09 | King Abdullah University Of Science And Technology | Laser-based agriculture system |
| US9897448B2 (en) | 2014-10-31 | 2018-02-20 | The Charles Stark Draper Laboratory, Inc. | Systems and methods for multiple species atom interferometry |
| US10331087B2 (en) | 2014-12-03 | 2019-06-25 | The Charles Stark Draper Laboratory, Inc. | Atom interferometry in dynamic environments |
| US11123366B1 (en) | 2014-12-15 | 2021-09-21 | Children's Hospital Of Orange County | Methods, materials, and systems for treating injuries to the central nervous system using light emitting nanoparticles |
| US20190022221A1 (en) | 2015-01-14 | 2019-01-24 | Immunolight, Llc. | Non-invasive systems and methods for treatment of a host carrying a virus with photoactivatable drugs |
| WO2017173315A1 (en) | 2016-04-01 | 2017-10-05 | Black Light Surgical, Inc. | Systems, devices, and methods for time-resolved fluorescent spectroscopy |
| CA3083789A1 (en) | 2017-11-29 | 2019-06-06 | The Rockefeller University | Combination of local and systemic therapies for enhanced treatment of dermatologic conditions |
| EP3773548B1 (en) | 2018-05-16 | 2023-08-09 | Provectus Pharmatech, Inc. | In vitro and xenograft anti-tumor activity of a halogenated-xanthene against refractory pediatric solid tumors |
| US11419844B2 (en) | 2019-11-19 | 2022-08-23 | Provectus Pharmatech, Inc. | Halogenated xanthene composition and method for treating hematologic cancers |
| US12064507B2 (en) | 2019-11-19 | 2024-08-20 | Provectus Pharmatech, Inc. | Composition and method for oral treatment of leukemia |
| US11938182B2 (en) | 2020-03-26 | 2024-03-26 | Provectus Pharmatech, Inc. | Halogenated xanthenes as vaccine adjuvants |
| MX2022011765A (es) | 2020-03-26 | 2022-11-09 | Provectus Pharmatech Inc | Usos novedosos de xantenos halogenados en oncologia y virologia. |
| CN111592920A (zh) * | 2020-05-21 | 2020-08-28 | 新沂百川畅银新能源有限公司 | 一种沼气脱硫净化工艺 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4578079A (en) * | 1982-08-04 | 1986-03-25 | La Jolla Cancer Research Foundation | Tetrapeptide |
| US4589881A (en) * | 1982-08-04 | 1986-05-20 | La Jolla Cancer Research Foundation | Polypeptide |
| JPS63111886A (ja) * | 1986-10-29 | 1988-05-17 | 呉羽化学工業株式会社 | 光ダイオ−ドを用いた癌治療装置 |
| US5053006A (en) * | 1988-04-19 | 1991-10-01 | Watson Brant D | Method for the permanent occlusion of arteries |
| US4925736A (en) * | 1988-07-06 | 1990-05-15 | Long Island Jewish Medical Center | Topical hematoporphyrin |
| US5654267A (en) * | 1988-12-20 | 1997-08-05 | La Jolla Cancer Research Center | Cooperative combinations of ligands contained within a matrix |
| US5498694A (en) * | 1989-05-25 | 1996-03-12 | La Jolla Cancer Research Foundation | Peptides of the cytoplasmic domain of integrin |
| US4973848A (en) * | 1989-07-28 | 1990-11-27 | J. Mccaughan | Laser apparatus for concurrent analysis and treatment |
| US5121398A (en) * | 1989-09-26 | 1992-06-09 | Excel Technology, Inc. | Broadly tunable, high repetition rate solid state lasers and uses thereof |
| US5034613A (en) * | 1989-11-14 | 1991-07-23 | Cornell Research Foundation, Inc. | Two-photon laser microscopy |
| EP0505355A4 (en) * | 1989-12-11 | 1992-12-30 | Lasb Laser, Corp. | Laser therapeutic apparatus and method |
| US5629291A (en) * | 1992-01-31 | 1997-05-13 | La Jolla Cancer Research Foundation | Methods of modulating fibronectin extracellular matrix assembly |
| US5627263A (en) * | 1993-11-24 | 1997-05-06 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
| US5558666A (en) * | 1994-01-14 | 1996-09-24 | Coherent, Inc. | Handpiece for producing highly collimated laser beam for dermatological procedures |
| US5586981A (en) * | 1994-08-25 | 1996-12-24 | Xin-Hua Hu | Treatment of cutaneous vascular and pigmented lesions |
| US5643334A (en) * | 1995-02-07 | 1997-07-01 | Esc Medical Systems Ltd. | Method and apparatus for the diagnostic and composite pulsed heating and photodynamic therapy treatment |
| US5576013A (en) * | 1995-03-21 | 1996-11-19 | Eastern Virginia Medical School | Treating vascular and neoplastic tissues |
| US5912257A (en) * | 1995-09-06 | 1999-06-15 | The Research Foundation Of State University Of New York | Two-photon upconverting dyes and applications |
| US5622699A (en) * | 1995-09-11 | 1997-04-22 | La Jolla Cancer Research Foundation | Method of identifying molecules that home to a selected organ in vivo |
| US5759767A (en) * | 1996-10-11 | 1998-06-02 | Joseph R. Lakowicz | Two-photon and multi-photon measurement of analytes in animal and human tissues and fluids |
| US5832931A (en) * | 1996-10-30 | 1998-11-10 | Photogen, Inc. | Method for improved selectivity in photo-activation and detection of molecular diagnostic agents |
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