KR19990022712A - aPL 면역반응성 펩티드, 그것의 콘주게이트 및 aPL항체-매개병변의 치료방법 - Google Patents

aPL 면역반응성 펩티드, 그것의 콘주게이트 및 aPL항체-매개병변의 치료방법

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Publication number
KR19990022712A
KR19990022712A KR1019970709154A KR19970709154A KR19990022712A KR 19990022712 A KR19990022712 A KR 19990022712A KR 1019970709154 A KR1019970709154 A KR 1019970709154A KR 19970709154 A KR19970709154 A KR 19970709154A KR 19990022712 A KR19990022712 A KR 19990022712A
Authority
KR
South Korea
Prior art keywords
apl
phage
antibody
peptide
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019970709154A
Other languages
English (en)
Korean (ko)
Inventor
에드워드 제스 빅토리아
데이비드 매튜 마르퀴스
데이비드 에스 존스
린 유
Original Assignee
와이즈맨 앤드류
라 졸라 파마슈티칼 컴파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 와이즈맨 앤드류, 라 졸라 파마슈티칼 컴파니 filed Critical 와이즈맨 앤드류
Publication of KR19990022712A publication Critical patent/KR19990022712A/ko
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/12Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/64Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
    • A61K2039/645Dendrimers; Multiple antigen peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1019970709154A 1995-06-07 1996-06-06 aPL 면역반응성 펩티드, 그것의 콘주게이트 및 aPL항체-매개병변의 치료방법 Ceased KR19990022712A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8/482651 1995-06-07
US08/482,651 US5874409A (en) 1995-06-07 1995-06-07 APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies

Publications (1)

Publication Number Publication Date
KR19990022712A true KR19990022712A (ko) 1999-03-25

Family

ID=23916889

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019970709154A Ceased KR19990022712A (ko) 1995-06-07 1996-06-06 aPL 면역반응성 펩티드, 그것의 콘주게이트 및 aPL항체-매개병변의 치료방법

Country Status (8)

Country Link
US (2) US5874409A (https=)
EP (1) EP0833648A4 (https=)
JP (1) JPH11507822A (https=)
KR (1) KR19990022712A (https=)
CN (1) CN1326557C (https=)
AU (1) AU711192B2 (https=)
CA (1) CA2223687A1 (https=)
WO (1) WO1996040197A1 (https=)

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US6410775B1 (en) * 1995-06-07 2002-06-25 La Jolla Pharmaceutical Company APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies
US5874409A (en) 1995-06-07 1999-02-23 La Jolla Pharmaceutical Company APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies
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US20030114405A1 (en) * 2001-08-13 2003-06-19 Linnik Matthew D. Methods of treating systemic lupus erythematosus in individuals having significantly impaired renal function
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US20080118487A1 (en) * 2004-09-30 2008-05-22 Orico Limited Myostatin Isoform
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Also Published As

Publication number Publication date
AU6271096A (en) 1996-12-30
US6207160B1 (en) 2001-03-27
EP0833648A1 (en) 1998-04-08
EP0833648A4 (en) 1999-10-13
WO1996040197A1 (en) 1996-12-19
JPH11507822A (ja) 1999-07-13
CN1326557C (zh) 2007-07-18
CA2223687A1 (en) 1996-12-19
US5874409A (en) 1999-02-23
AU711192B2 (en) 1999-10-07
CN1192153A (zh) 1998-09-02

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