KR102797112B1 - 유전자 총 - Google Patents

유전자 총 Download PDF

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Publication number
KR102797112B1
KR102797112B1 KR1020227017574A KR20227017574A KR102797112B1 KR 102797112 B1 KR102797112 B1 KR 102797112B1 KR 1020227017574 A KR1020227017574 A KR 1020227017574A KR 20227017574 A KR20227017574 A KR 20227017574A KR 102797112 B1 KR102797112 B1 KR 102797112B1
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KR
South Korea
Prior art keywords
particular embodiment
accelerator module
particles
wave
detonation
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KR1020227017574A
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English (en)
Korean (ko)
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KR20220092914A (ko
Inventor
데이비드 마이클 포먼
Original Assignee
주식회사 다이셀
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Publication of KR20220092914A publication Critical patent/KR20220092914A/ko
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Publication of KR102797112B1 publication Critical patent/KR102797112B1/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/30Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2046Media being expelled from injector by gas generation, e.g. explosive charge
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/30Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M5/3007Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules with specially designed jet passages at the injector's distal end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/30Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M5/3015Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • CCHEMISTRY; METALLURGY
    • C06EXPLOSIVES; MATCHES
    • C06CDETONATING OR PRIMING DEVICES; FUSES; CHEMICAL LIGHTERS; PYROPHORIC COMPOSITIONS
    • C06C7/00Non-electric detonators; Blasting caps; Primers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/89Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
    • C12N15/895Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection using biolistic methods

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
KR1020227017574A 2019-10-30 2020-10-29 유전자 총 Active KR102797112B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962928280P 2019-10-30 2019-10-30
US62/928,280 2019-10-30
PCT/JP2020/040705 WO2021085564A1 (ja) 2019-10-30 2020-10-29 遺伝子銃

Publications (2)

Publication Number Publication Date
KR20220092914A KR20220092914A (ko) 2022-07-04
KR102797112B1 true KR102797112B1 (ko) 2025-04-18

Family

ID=75715193

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227017574A Active KR102797112B1 (ko) 2019-10-30 2020-10-29 유전자 총

Country Status (6)

Country Link
US (1) US20220362473A1 (https=)
EP (1) EP4052745A4 (https=)
JP (2) JP7704684B2 (https=)
KR (1) KR102797112B1 (https=)
CN (2) CN120242238A (https=)
WO (1) WO2021085564A1 (https=)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018991A1 (en) 1990-05-29 1991-12-12 E.I. Du Pont De Nemours And Company Improved method and apparatus for introducing biological substances into living cells
JP2000502036A (ja) 1995-12-20 2000-02-22 ニトロ・ノーベル・アクチエボラーグ 雷管のための火工品装薬
JP2001523328A (ja) 1997-04-09 2001-11-20 ジ・エンサイン−ビツクフオード・カンパニー 緩く充填された点火装薬を含む起爆装置及び集成方法
JP2004236657A (ja) 2003-02-03 2004-08-26 Bioware Technology Co Ltd 低圧ガス加速遺伝子銃
US20100198146A1 (en) 2009-02-05 2010-08-05 Gopalan Jagadeesh Apparatus and method for delivering biologically-active substances or micro-medical devices to a target
US20170216530A1 (en) 2014-08-02 2017-08-03 Peter Lell Needle-free injection device comprising a membrane
JP2017535033A (ja) 2014-10-22 2017-11-24 レル ピーター 火薬式駆動装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE462391B (sv) * 1984-08-23 1990-06-18 China Met Imp Exp Shougang Spraengkapsel och initieringselement innehaallande icke-primaerspraengaemne
EP1545593A1 (en) 2002-09-27 2005-06-29 PowderJect Research Limited Nucleic acid coated particles
US20040162517A1 (en) * 2002-12-04 2004-08-19 Otto Furst Needleless hydpodermic injection device with non-electric ignition means
DE10306716A1 (de) * 2003-02-17 2004-09-02 Lell, Peter, Dr.-Ing. Vorrichtung zum Injizieren eines staub-oder pulverförmigen Stoffs in ein Gewebe eines Körpers
EP2959931A1 (de) 2014-06-24 2015-12-30 LTS LOHMANN Therapie-Systeme AG Nadellose Injektionsvorrichtung

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018991A1 (en) 1990-05-29 1991-12-12 E.I. Du Pont De Nemours And Company Improved method and apparatus for introducing biological substances into living cells
JP2000502036A (ja) 1995-12-20 2000-02-22 ニトロ・ノーベル・アクチエボラーグ 雷管のための火工品装薬
JP2001523328A (ja) 1997-04-09 2001-11-20 ジ・エンサイン−ビツクフオード・カンパニー 緩く充填された点火装薬を含む起爆装置及び集成方法
JP2004236657A (ja) 2003-02-03 2004-08-26 Bioware Technology Co Ltd 低圧ガス加速遺伝子銃
US20100198146A1 (en) 2009-02-05 2010-08-05 Gopalan Jagadeesh Apparatus and method for delivering biologically-active substances or micro-medical devices to a target
US20170216530A1 (en) 2014-08-02 2017-08-03 Peter Lell Needle-free injection device comprising a membrane
JP2017535033A (ja) 2014-10-22 2017-11-24 レル ピーター 火薬式駆動装置

Also Published As

Publication number Publication date
EP4052745A1 (en) 2022-09-07
US20220362473A1 (en) 2022-11-17
KR20220092914A (ko) 2022-07-04
CN114641328A (zh) 2022-06-17
EP4052745A4 (en) 2023-11-01
JPWO2021085564A1 (https=) 2021-05-06
JP2025129249A (ja) 2025-09-04
CN114641328B (zh) 2025-04-01
CN120242238A (zh) 2025-07-04
WO2021085564A1 (ja) 2021-05-06
JP7704684B2 (ja) 2025-07-08

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