KR102795351B1 - 메틸락탐환 화합물 및 그의 의약 용도 - Google Patents

메틸락탐환 화합물 및 그의 의약 용도 Download PDF

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KR102795351B1
KR102795351B1 KR1020207025856A KR20207025856A KR102795351B1 KR 102795351 B1 KR102795351 B1 KR 102795351B1 KR 1020207025856 A KR1020207025856 A KR 1020207025856A KR 20207025856 A KR20207025856 A KR 20207025856A KR 102795351 B1 KR102795351 B1 KR 102795351B1
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KR20200128033A (ko
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도모야 미우라
요시노리 다마타니
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니뽄 다바코 산교 가부시키가이샤
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020207025856A 2018-03-01 2019-02-28 메틸락탐환 화합물 및 그의 의약 용도 Active KR102795351B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018036307 2018-03-01
JPJP-P-2018-036307 2018-03-01
PCT/JP2019/007799 WO2019168096A1 (ja) 2018-03-01 2019-02-28 メチルラクタム環化合物及びその医薬用途

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Publication Number Publication Date
KR20200128033A KR20200128033A (ko) 2020-11-11
KR102795351B1 true KR102795351B1 (ko) 2025-04-16

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Country Status (21)

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US (3) US11014910B2 (https=)
EP (1) EP3760624A4 (https=)
JP (3) JP7206132B2 (https=)
KR (1) KR102795351B1 (https=)
CN (1) CN111757877B (https=)
AR (1) AR114418A1 (https=)
AU (1) AU2019227770B2 (https=)
BR (1) BR112020016788A2 (https=)
CA (1) CA3087859A1 (https=)
CL (1) CL2020002199A1 (https=)
IL (1) IL276311B2 (https=)
MA (1) MA52427A (https=)
MX (1) MX2020009070A (https=)
MY (1) MY205197A (https=)
PE (1) PE20210123A1 (https=)
PH (1) PH12020551340A1 (https=)
SA (1) SA520420037B1 (https=)
SG (1) SG11202007120UA (https=)
TW (1) TWI805699B (https=)
WO (1) WO2019168096A1 (https=)
ZA (1) ZA202004600B (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI805699B (zh) * 2018-03-01 2023-06-21 日商日本煙草產業股份有限公司 甲基內醯胺環化合物及其用途
EP3778593A4 (en) 2018-04-04 2021-12-22 Japan Tobacco Inc. HETEROARYL-SUBSTITUTED PYRAZOLE COMPOUND AND ITS MEDICAL USE
JP7760370B2 (ja) * 2019-09-04 2025-10-27 日本たばこ産業株式会社 慢性腎臓病の治療又は予防方法
US20230119894A1 (en) * 2019-09-04 2023-04-20 Japan Tobacco Inc. Therapeutic or prophylactic method for diabetes using combination medicine
CA3175131A1 (en) 2020-03-19 2021-09-23 Chihiro Okuma Treatment or prevention method for chronic heart failure

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WO2007034279A2 (en) 2005-09-19 2007-03-29 Pfizer Products Inc. C3a antagonists and pharmaceutical compositions thereof
JP2007332034A (ja) 2005-06-08 2007-12-27 Japan Tobacco Inc 複素環化合物
JP2009534439A (ja) 2006-04-27 2009-09-24 ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｂｘカンナビノイド受容体モジュレータ及びカリウムチャンネルモジュレータを含む医薬組成物
JP2010523583A (ja) 2007-04-02 2010-07-15 セラコス・インコーポレイテッド ベンジルグルコシド誘導体およびその用途
WO2013031922A1 (ja) 2011-08-31 2013-03-07 日本たばこ産業株式会社 ピラゾール化合物及びその医薬用途

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FR2665898B1 (fr) 1990-08-20 1994-03-11 Sanofi Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
JPH04247081A (ja) 1991-02-01 1992-09-03 Takeda Chem Ind Ltd ５員複素環酸アミド類
FR2692575B1 (fr) 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
US7622471B2 (en) 2003-02-07 2009-11-24 Daiichi Pharmaceutical Co., Ltd. Pyrazole derivatives having a pyridazine and pyridine functionality
AU2004200420A1 (en) 2003-03-11 2004-09-30 Astellas Pharma Inc. Inhibitor of cyclooxygenase
JP2006182648A (ja) 2003-04-08 2006-07-13 Dai Ichi Seiyaku Co Ltd ７員複素環誘導体
WO2004110351A2 (en) 2003-05-14 2004-12-23 Anadys Pharmaceuticals, Inc. Heterocyclic compounds for treating hepatitis c virus
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TW200526641A (en) 2003-12-26 2005-08-16 Daiichi Seiyaku Co Amidopyrazole derivatives
CN1980665A (zh) 2004-07-07 2007-06-13 默克公司 吡唑酰胺衍生物，包含这些化合物的组合物和使用方法
AU2005305675B2 (en) 2004-11-16 2012-12-13 Jazz Pharmaceuticals Operations Uk Limited New use for cannabinoid
JP2008007405A (ja) 2004-12-07 2008-01-17 Takeda Chem Ind Ltd カルボキサミド誘導体
KR100970294B1 (ko) 2005-06-08 2010-07-15 니뽄 다바코 산교 가부시키가이샤 복소환 화합물
ZA200800142B (en) * 2005-06-08 2009-05-27 Japan Tobacco Inc Heterocyclic compound
WO2007098826A2 (en) 2006-01-18 2007-09-07 Siena Biotech S.P.A. Modulators of alpha7 nicotinic acetylcholine receptors and therapeutic uses thereof
US20080027014A1 (en) 2006-07-28 2008-01-31 Tanabe Seiyaku Co., Ltd. Novel SGLT inhibitors
KR101450356B1 (ko) 2006-11-24 2014-10-15 에이씨 이뮨 에스.에이. 알츠하이머와 같은 아밀로이드 또는 아밀로이드-유사 단백질과 관련된 질환의 치료를 위한 ｎ-(메틸)-1ｈ-피라졸-3-아민, ｎ-(메틸)-피리딘-2-아민 및 ｎ-(메틸)-티아졸-2-아민 유도체
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TW200901974A (en) 2007-01-16 2009-01-16 Wyeth Corp Compounds, compositions, and methods of making and using them
WO2009091813A1 (en) 2008-01-14 2009-07-23 Wyeth Compounds useful as alpha7 nicotinic acetylcholine receptor agonists
EP2349484A2 (en) 2008-07-15 2011-08-03 Novartis AG Heteroaryl derivatives as dgat1 inhibitors
CN102918034B (zh) 2010-03-30 2015-06-03 维颂公司 多取代芳族化合物作为凝血酶的抑制剂
KR102727059B1 (ko) * 2015-02-16 2024-11-05 더 유니버서티 어브 퀸슬랜드 설포닐우레아와 관련 화합물 및 그 용도
CN109071454B (zh) * 2016-02-16 2023-02-17 昆士兰大学 磺酰脲和相关化合物及其用途
TWI805699B (zh) * 2018-03-01 2023-06-21 日商日本煙草產業股份有限公司 甲基內醯胺環化合物及其用途
EP3778593A4 (en) 2018-04-04 2021-12-22 Japan Tobacco Inc. HETEROARYL-SUBSTITUTED PYRAZOLE COMPOUND AND ITS MEDICAL USE

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007332034A (ja) 2005-06-08 2007-12-27 Japan Tobacco Inc 複素環化合物
WO2007034279A2 (en) 2005-09-19 2007-03-29 Pfizer Products Inc. C3a antagonists and pharmaceutical compositions thereof
JP2009534439A (ja) 2006-04-27 2009-09-24 ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｂｘカンナビノイド受容体モジュレータ及びカリウムチャンネルモジュレータを含む医薬組成物
JP2010523583A (ja) 2007-04-02 2010-07-15 セラコス・インコーポレイテッド ベンジルグルコシド誘導体およびその用途
WO2013031922A1 (ja) 2011-08-31 2013-03-07 日本たばこ産業株式会社 ピラゾール化合物及びその医薬用途

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CL2020002199A1 (es) 2020-12-18
JP2023026566A (ja) 2023-02-24
MA52427A (fr) 2021-01-06
SA520420037B1 (ar) 2024-07-28
TWI805699B (zh) 2023-06-21
CN111757877A (zh) 2020-10-09
EP3760624A4 (en) 2021-11-03
PH12020551340A1 (en) 2021-05-31
US20190352284A1 (en) 2019-11-21
WO2019168096A1 (ja) 2019-09-06
MY205197A (en) 2024-10-07
US11014910B2 (en) 2021-05-25
CA3087859A1 (en) 2019-09-06
AU2019227770A1 (en) 2020-07-09
RU2020131756A (ru) 2022-03-28
TW202000660A (zh) 2020-01-01
BR112020016788A2 (pt) 2021-01-12
AR114418A1 (es) 2020-09-02
ZA202004600B (en) 2022-03-30
JP2019151627A (ja) 2019-09-12
IL276311A (en) 2020-09-30
JP2025026615A (ja) 2025-02-21
MX2020009070A (es) 2020-10-08
IL276311B2 (en) 2023-10-01
IL276311B1 (en) 2023-06-01
US20240174646A1 (en) 2024-05-30
EP3760624A1 (en) 2021-01-06
CN111757877B (zh) 2023-10-27
JP7206132B2 (ja) 2023-01-17
SG11202007120UA (en) 2020-08-28
KR20200128033A (ko) 2020-11-11
PE20210123A1 (es) 2021-01-19
US20220064148A1 (en) 2022-03-03
AU2019227770B2 (en) 2023-10-05

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