PE20210123A1 - Compuesto de anillo de metillactama y uso farmaceutico del mismo - Google Patents

Compuesto de anillo de metillactama y uso farmaceutico del mismo

Info

Publication number
PE20210123A1
PE20210123A1 PE2020001287A PE2020001287A PE20210123A1 PE 20210123 A1 PE20210123 A1 PE 20210123A1 PE 2020001287 A PE2020001287 A PE 2020001287A PE 2020001287 A PE2020001287 A PE 2020001287A PE 20210123 A1 PE20210123 A1 PE 20210123A1
Authority
PE
Peru
Prior art keywords
pharmaceutical use
methyllactam
same
ring compound
compound
Prior art date
Application number
PE2020001287A
Other languages
English (en)
Inventor
Tomoya Miura
Yoshinori Tamatani
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of PE20210123A1 publication Critical patent/PE20210123A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La presente invencion se refiere a un compuesto de Formula I que comprende un anillo de metillactama y que tiene una actividad inhibidora de SGLT1 o una sal farmaceuticamente aceptable del mismo, tambien esta referido a una composicion farmaceutica que lo comprende, y al uso farmaceutico del mismo. Este compuesto es util en el tratamiento de patologias diabeticas (aumento de glucosa en sangre)
PE2020001287A 2018-03-01 2019-02-28 Compuesto de anillo de metillactama y uso farmaceutico del mismo PE20210123A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018036307 2018-03-01
PCT/JP2019/007799 WO2019168096A1 (ja) 2018-03-01 2019-02-28 メチルラクタム環化合物及びその医薬用途

Publications (1)

Publication Number Publication Date
PE20210123A1 true PE20210123A1 (es) 2021-01-19

Family

ID=67806229

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2020001287A PE20210123A1 (es) 2018-03-01 2019-02-28 Compuesto de anillo de metillactama y uso farmaceutico del mismo

Country Status (19)

Country Link
US (2) US11014910B2 (es)
EP (1) EP3760624A4 (es)
JP (2) JP7206132B2 (es)
KR (1) KR20200128033A (es)
CN (1) CN111757877B (es)
AR (1) AR114418A1 (es)
AU (1) AU2019227770B2 (es)
BR (1) BR112020016788A2 (es)
CA (1) CA3087859A1 (es)
CL (1) CL2020002199A1 (es)
IL (1) IL276311B2 (es)
MA (1) MA52427A (es)
MX (1) MX2020009070A (es)
PE (1) PE20210123A1 (es)
PH (1) PH12020551340A1 (es)
SG (1) SG11202007120UA (es)
TW (1) TWI805699B (es)
WO (1) WO2019168096A1 (es)
ZA (1) ZA202004600B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019249560B2 (en) 2018-04-04 2023-10-05 Japan Tobacco Inc. Heteroaryl-substituted pyrazole compound and medicinal use thereof
AU2020341926A1 (en) * 2019-09-04 2022-03-17 Japan Tobacco Inc. Therapeutic or prophylactic method for diabetes using combination medicine
BR112022018396A2 (pt) 2020-03-19 2022-11-08 Japan Tobacco Inc Método de tratamento ou prevenção para insuficiência cardíaca crônica

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665898B1 (fr) 1990-08-20 1994-03-11 Sanofi Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
JPH04247081A (ja) 1991-02-01 1992-09-03 Takeda Chem Ind Ltd ５員複素環酸アミド類
FR2692575B1 (fr) 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
KR20050096956A (ko) 2003-02-07 2005-10-06 다이이찌 세이야꾸 가부시기가이샤 피라졸 유도체
AU2004200420A1 (en) 2003-03-11 2004-09-30 Astellas Pharma Inc. Inhibitor of cyclooxygenase
JP2006182648A (ja) 2003-04-08 2006-07-13 Dai Ichi Seiyaku Co Ltd ７員複素環誘導体
US20050075375A1 (en) 2003-05-14 2005-04-07 Anadys Pharmaceuticals, Inc. Heterocyclic compounds for treating hepatitis C virus
TW200526588A (en) 2003-11-17 2005-08-16 Smithkline Beecham Corp Chemical compounds
TW200526641A (en) 2003-12-26 2005-08-16 Daiichi Seiyaku Co Amidopyrazole derivatives
CA2572745A1 (en) 2004-07-07 2006-02-16 Teresa Beeson Pyrazole amide derivatives, compositions containing such compounds and methods of use
US9168278B2 (en) 2004-11-16 2015-10-27 Gw Pharma Limited Use for cannabinoid
JP2008007405A (ja) 2004-12-07 2008-01-17 Takeda Chem Ind Ltd カルボキサミド誘導体
JP4137956B2 (ja) * 2005-06-08 2008-08-20 日本たばこ産業株式会社 複素環化合物
CN101243074A (zh) * 2005-06-08 2008-08-13 日本烟草产业株式会社 杂环化合物
EP1889842A4 (en) 2005-06-08 2009-07-29 Japan Tobacco Inc HETEROCYCLIC CONNECTION
WO2007034279A2 (en) * 2005-09-19 2007-03-29 Pfizer Products Inc. C3a antagonists and pharmaceutical compositions thereof
JP2009523748A (ja) 2006-01-18 2009-06-25 シエナ ビオテク ソシエタ ペル アチオニ α７ニコチン性アセチルコリン受容体の調節物質およびそれらの治療への使用
EA200802132A1 (ru) * 2006-04-27 2009-06-30 Зольвай Фармасьютиклз Гмбх Фармацевтические композиции, содержащие модуляторы каннабиноидного рецептора cbи модуляторы калиевых каналов
US20080027014A1 (en) 2006-07-28 2008-01-31 Tanabe Seiyaku Co., Ltd. Novel SGLT inhibitors
CN102838532A (zh) 2006-11-24 2012-12-26 Ac免疫有限公司 用于治疗与淀粉样物质或淀粉样蛋白有关的疾病的吡唑胺和噻唑胺衍生物
US20100144793A1 (en) 2006-11-24 2010-06-10 Ac Immune Sa Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
TW200901974A (en) 2007-01-16 2009-01-16 Wyeth Corp Compounds, compositions, and methods of making and using them
US7838498B2 (en) * 2007-04-02 2010-11-23 Theracos, Inc. Benzylic glycoside derivatives and methods of use
US20090181952A1 (en) 2008-01-14 2009-07-16 Wyeth Compounds useful as alpha7 nicotinic acetylcholine receptor agonists
KR20110028661A (ko) 2008-07-15 2011-03-21 노파르티스 아게 Ｄｇａｔ１ 억제제로서의 헤테로아릴 유도체
AU2011238616B2 (en) 2010-03-30 2016-08-04 Verseon Corporation Multisubstituted aromatic compounds as inhibitors of thrombin
AR087701A1 (es) 2011-08-31 2014-04-09 Japan Tobacco Inc Derivados de pirazol con actividad inhibidora de sglt1
AU2019249560B2 (en) 2018-04-04 2023-10-05 Japan Tobacco Inc. Heteroaryl-substituted pyrazole compound and medicinal use thereof

Also Published As

Publication number Publication date
US20190352284A1 (en) 2019-11-21
CA3087859A1 (en) 2019-09-06
PH12020551340A1 (en) 2021-05-31
ZA202004600B (en) 2022-03-30
US20220064148A1 (en) 2022-03-03
JP7206132B2 (ja) 2023-01-17
AR114418A1 (es) 2020-09-02
IL276311B2 (en) 2023-10-01
AU2019227770A1 (en) 2020-07-09
WO2019168096A1 (ja) 2019-09-06
JP2023026566A (ja) 2023-02-24
JP2019151627A (ja) 2019-09-12
AU2019227770B2 (en) 2023-10-05
MX2020009070A (es) 2020-10-08
TW202000660A (zh) 2020-01-01
MA52427A (fr) 2021-01-06
KR20200128033A (ko) 2020-11-11
US11014910B2 (en) 2021-05-25
SG11202007120UA (en) 2020-08-28
EP3760624A1 (en) 2021-01-06
CL2020002199A1 (es) 2020-12-18
EP3760624A4 (en) 2021-11-03
IL276311B1 (en) 2023-06-01
BR112020016788A2 (pt) 2021-01-12
CN111757877A (zh) 2020-10-09
CN111757877B (zh) 2023-10-27
TWI805699B (zh) 2023-06-21
RU2020131756A (ru) 2022-03-28
IL276311A (en) 2020-09-30

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