KR102794702B1 - 암의 치료를 위한 bcma 및 taci 항원에 특이적인 면역원성 펩타이드 - Google Patents

암의 치료를 위한 bcma 및 taci 항원에 특이적인 면역원성 펩타이드 Download PDF

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KR102794702B1
KR102794702B1 KR1020207009561A KR20207009561A KR102794702B1 KR 102794702 B1 KR102794702 B1 KR 102794702B1 KR 1020207009561 A KR1020207009561 A KR 1020207009561A KR 20207009561 A KR20207009561 A KR 20207009561A KR 102794702 B1 KR102794702 B1 KR 102794702B1
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peptide
cells
bcma
cancer
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KR20200047660A (ko
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주은 배
니킬 씨 문시
케네스 씨 앤더슨
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다나-파버 캔서 인스티튜트 인크.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
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    • A61K2039/55511—Organic adjuvants
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    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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    • A61K2039/6031—Proteins
    • A61K2039/605—MHC molecules or ligands thereof

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KR1020207009561A 2017-09-01 2018-08-31 암의 치료를 위한 bcma 및 taci 항원에 특이적인 면역원성 펩타이드 Active KR102794702B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762553669P 2017-09-01 2017-09-01
US62/553,669 2017-09-01
PCT/US2018/049260 WO2019046818A1 (en) 2017-09-01 2018-08-31 SPECIFIC IMMUNOGENIC PEPTIDES OF BCMA AND TACI ANTIGENS FOR THE TREATMENT OF CANCER

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KR20200047660A KR20200047660A (ko) 2020-05-07
KR102794702B1 true KR102794702B1 (ko) 2025-04-11

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KR1020207009561A Active KR102794702B1 (ko) 2017-09-01 2018-08-31 암의 치료를 위한 bcma 및 taci 항원에 특이적인 면역원성 펩타이드

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US (2) US11517591B2 (https=)
EP (1) EP3675897A1 (https=)
JP (2) JP7385556B2 (https=)
KR (1) KR102794702B1 (https=)
CN (1) CN111655280B (https=)
AU (2) AU2018326805B2 (https=)
CA (1) CA3070468A1 (https=)
WO (1) WO2019046818A1 (https=)

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