KR102790669B1 - 합성 드래그라인 거미 실크를 포함하는 복합체 - Google Patents

합성 드래그라인 거미 실크를 포함하는 복합체 Download PDF

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KR102790669B1
KR102790669B1 KR1020187025745A KR20187025745A KR102790669B1 KR 102790669 B1 KR102790669 B1 KR 102790669B1 KR 1020187025745 A KR1020187025745 A KR 1020187025745A KR 20187025745 A KR20187025745 A KR 20187025745A KR 102790669 B1 KR102790669 B1 KR 102790669B1
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proteins
fibers
mixture
polymer
protein
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KR20180107236A (ko
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쉬뮬릭 잇타
메니 시멜
엘라 스크란
드가닛 스테른
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시비스 머테리얼 사이언스 리미티드
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01DMECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00Formation of filaments, threads, or the like
    • D01D5/0007Electro-spinning
    • D01D5/0015Electro-spinning characterised by the initial state of the material
    • D01D5/003Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion
    • D01D5/0038Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion the fibre formed by solvent evaporation, i.e. dry electro-spinning
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F1/00General methods for the manufacture of artificial filaments or the like
    • D01F1/02Addition of substances to the spinning solution or to the melt
    • D01F1/10Other agents for modifying properties
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • D01F4/02Monocomponent artificial filaments or the like of proteins; Manufacture thereof from fibroin
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/88Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2211/00Protein-based fibres, e.g. animal fibres
    • D10B2211/01Natural animal fibres, e.g. keratin fibres
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2211/00Protein-based fibres, e.g. animal fibres
    • D10B2211/01Natural animal fibres, e.g. keratin fibres
    • D10B2211/04Silk
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2331/00Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2331/00Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products
    • D10B2331/02Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyamides
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2331/00Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products
    • D10B2331/04Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyesters, e.g. polyethylene terephthalate [PET]
    • D10B2331/041Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyesters, e.g. polyethylene terephthalate [PET] derived from hydroxy-carboxylic acids, e.g. lactones
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2331/00Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products
    • D10B2331/10Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyurethanes
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2401/00Physical properties
    • D10B2401/06Load-responsive characteristics
    • D10B2401/061Load-responsive characteristics elastic
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2401/00Physical properties
    • D10B2401/06Load-responsive characteristics
    • D10B2401/063Load-responsive characteristics high strength

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Textile Engineering (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Manufacturing & Machinery (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Artificial Filaments (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020187025745A 2016-02-11 2017-02-12 합성 드래그라인 거미 실크를 포함하는 복합체 Active KR102790669B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662293880P 2016-02-11 2016-02-11
US62/293,880 2016-02-11
US201662317572P 2016-04-03 2016-04-03
US62/317,572 2016-04-03
ILPCT/IL2016/050874 2016-08-10
PCT/IL2016/050874 WO2017025964A1 (en) 2015-08-10 2016-08-10 Compositions and methods for fabricating synthetic dragline spider silk
PCT/IL2017/050175 WO2017138002A1 (en) 2016-02-11 2017-02-12 Composite materials comprising synthetic dragline spider silk

Publications (2)

Publication Number Publication Date
KR20180107236A KR20180107236A (ko) 2018-10-01
KR102790669B1 true KR102790669B1 (ko) 2025-04-04

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US (2) US11345727B2 (enExample)
EP (2) EP3414373B1 (enExample)
JP (2) JP7176736B2 (enExample)
KR (1) KR102790669B1 (enExample)
CN (1) CN109477252A (enExample)
AU (1) AU2017218794B2 (enExample)
BR (1) BR112018016472A2 (enExample)
CA (1) CA3014537A1 (enExample)
WO (1) WO2017138002A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109477252A (zh) 2016-02-11 2019-03-15 赛威克斯材料科学公司 包括合成拖丝蜘蛛丝的复合材料
WO2019054481A1 (ja) * 2017-09-14 2019-03-21 バンドー化学株式会社 ゴム組成物及びそれを用いた伝動ベルト
EP3808882B1 (en) * 2018-04-03 2025-04-30 Hasetora Spinning Co., Ltd. Blended yarn, knitted/woven body of same, and method for manufacturing said knitted/woven body
US12202864B2 (en) 2018-10-31 2025-01-21 University Of Massachusetts Silk nucleotides and proteins and methods of use
US20230201413A1 (en) * 2019-03-11 2023-06-29 Seevix Material Sciences Ltd. Compositions comprising dragline spider silk
AU2020299495A1 (en) * 2019-07-04 2022-01-20 Seevix Material Sciences Ltd. Prokaryotic expression system and methods of using the same
TW202144386A (zh) * 2020-02-12 2021-12-01 美商保爾特紡織品公司 重組絲固體及膜
TW202200225A (zh) * 2020-03-18 2022-01-01 美商千禧製藥公司 可植入細胞腔室裝置及其用途
JP2023522994A (ja) 2020-04-23 2023-06-01 シービックス マテリアル サイエンシーズ リミテッド 修飾されたスパイダーシルク繊維およびその使用
US11732238B2 (en) 2020-05-04 2023-08-22 University Of Connecticut Main-chain liquid crystalline hydrogels for cell culture
EP4161094A4 (en) * 2020-06-02 2024-07-03 Foster Electric Company, Limited ELECTRO-ACOUSTIC TRANSDUCER MEMBRANE
CN115996744A (zh) * 2020-07-05 2023-04-21 赛威克斯材料科学公司 高度多孔蛛丝纤维
US12024540B2 (en) * 2021-05-20 2024-07-02 Samsung Electronics Co., Ltd. Polypetide, photoresist composition including the same, and method of forming pattern using the same
CN113668142B (zh) * 2021-09-29 2022-11-04 广州市醒目医药科技有限公司 医疗卫生用抗菌无纺布及生产方法
KR20230083100A (ko) * 2021-12-02 2023-06-09 삼성전자주식회사 폴리펩티드, 이를 포함하는 포토레지스트 조성물 및 이를 이용한 패턴 형성 방법
WO2023167628A1 (en) * 2022-03-04 2023-09-07 Anna Rising Recombinant spider silk proteins
CN116376070A (zh) * 2023-01-10 2023-07-04 无锡祺杰科技有限公司 一种强度高弹性拉力大的pe缠绕膜生产方法
KR102640338B1 (ko) * 2023-04-19 2024-02-23 김홍수 균열 저항성이 우수한 마이크로 콘크리트 보수 모르타르 조성물 및 이를 이용한 콘크리트 구조물의 보수 시공방법

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008507260A (ja) * 2004-06-25 2008-03-13 テヒニシェ ウニヴェルズィテート ミュンヘン 天然起源のタンパク質およびそれから作られる材料
WO2011113592A1 (en) 2010-03-17 2011-09-22 Amsilk Gmbh Method for production of polymer containing fibres
US20120022005A1 (en) 2010-05-24 2012-01-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Synthetic Dragline Spider Silk-Like Proteins
JP2015532690A (ja) * 2012-09-06 2015-11-12 アーエムシルク ゲーエムベーハー 高靱性シルク繊維を作製する方法

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755560A (en) 1971-06-30 1973-08-28 Dow Chemical Co Nongreasy cosmetic lotions
US4421769A (en) 1981-09-29 1983-12-20 The Procter & Gamble Company Skin conditioning composition
US5011681A (en) 1989-10-11 1991-04-30 Richardson-Vicks, Inc. Facial cleansing compositions
CA2459777A1 (en) 2001-08-29 2003-03-13 University Of Wyoming Spider silk protein encoding nucleic acids, polypeptides, antibodies and method of use thereof
US7057023B2 (en) 2002-01-11 2006-06-06 Nexia Biotechnologies Inc. Methods and apparatus for spinning spider silk protein
WO2003060099A2 (en) * 2002-01-11 2003-07-24 Nexia Biotechnologies, Inc. Methods and apparatus for spinning spider silk protein
EP3351376B1 (en) 2002-06-24 2023-04-12 Tufts University Silk biomaterials and methods of use thereof
US8030024B2 (en) 2004-06-25 2011-10-04 Amsilk Gmbh Synthesis of spider dragline and/or flagelliform proteins
WO2006002843A1 (en) 2004-06-29 2006-01-12 Corus Staal Bv Steel sheet with hot dip galvanized zinc alloy coating and process to produce it
EP1773875B1 (en) 2004-07-22 2014-09-10 Amsilk GmbH Recombinant spider silk proteins
RU2421463C2 (ru) 2005-08-29 2011-06-20 АЭмЗильк ГмбХ Способ модификации белка шелка пауков, модифицированный белок шелка пауков, кодирующая его последовательность нуклеиновой кислоты, вектор и клетка-хозяин для его экспрессии
CA2635660C (en) 2005-12-30 2016-02-23 Spiber Technologies Ab Spider silk proteins and methods for producing spider silk proteins
KR100894265B1 (ko) 2007-06-05 2009-04-21 재단법인서울대학교산학협력재단 골형성 촉진 펩타이드를 함유하는 주입형 골재생재
US11890371B2 (en) 2007-12-26 2024-02-06 Petvivo Holdings, Inc. Biocompatible protein-based particles and methods thereof
WO2010123947A2 (en) 2009-04-20 2010-10-28 Allergan, Inc. Silk fibroin hydrogels and uses thereof
US20110189292A1 (en) 2009-04-20 2011-08-04 Allergan, Inc. Dermal fillers comprising silk fibroin hydrogels and uses thereof
EP2506837B1 (en) 2009-11-30 2020-07-01 Amsilk GmbH Spider silk particles for controlled and sustained delivery of compounds
EP3495381A1 (en) 2009-12-08 2019-06-12 AMSilk GmbH Silk protein coatings
JP5691052B2 (ja) 2010-09-10 2015-04-01 岡本株式会社 組換え生物及び組換え生物により作られるタンパク質
CN102475909A (zh) 2010-11-22 2012-05-30 大连创达技术交易市场有限公司 一种组织工程用多孔支架材料
RU2451023C1 (ru) 2010-11-25 2012-05-20 Владимир Григорьевич Богуш Способ получения рекомбинантного белка паутины, слитый белок, рекомбинантная днк, вектор экспрессии, клетка-хозяин и штаммы-продуценты
PT2681280T (pt) 2011-02-28 2019-07-10 The Royal Institution For The Advancement Of Learning / Mcgill Univ Biomaterial, método para preparar o biomaterial e utilizações do mesmo
DE102011105372A1 (de) 2011-06-20 2012-12-20 Carl Freudenberg Kg Stabile, wässrige Protein-Lösung oder Protein-Dispersion, Verfahren zur Herstellung der stabilen, wässrigen Lösung oder Dispersion und Verfahren zur Herstellung von Form-oder Flächengebilden, Imprägnierungen oder Beschichtungen aus der stabilen, wässrigen Protein-Lösung oder Protein-Dispersion sowie deren Verwendung
BR112014011188B1 (pt) 2011-11-09 2020-05-19 Trustees Of Tufts College composição injetável para utilização na reparação ou aumento de tecido em indivíduo e dispositivo de entrega compreendendo a referida composição
NL1039495C2 (nl) 2012-03-27 2013-09-30 Jalila Essaidi Werkwijze ter vervaardiging van een huidsubstituut op basis van spinnenzijde alsmede draagstructuur vervaardigd onder toepassing van deze werkwijze en draagstructuur met doorgroeiende levende huid.
WO2013152265A1 (en) 2012-04-06 2013-10-10 Trustees Of Tufts College Methods of producing and using silk microfibers
AU2013255815B2 (en) 2012-05-02 2018-03-29 Spiber Technologies Ab Spider silk fusion protein structures without repetitive fragment for binding to an organic target
WO2014011644A1 (en) 2012-07-09 2014-01-16 Trustees Of Tufts College High molecular weight silk fibroin and uses thereof
EP2970411B1 (en) 2013-03-15 2018-05-09 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
GB201416089D0 (en) 2014-09-11 2014-10-29 Univ Nottingham Modified spider silk
US9714273B2 (en) 2014-10-08 2017-07-25 Utah State University Expression systems and associated methods
US20160298265A1 (en) * 2015-04-10 2016-10-13 Utah State University Spider silk and synthetic polymer fiber blends
WO2017025964A1 (en) 2015-08-10 2017-02-16 Seevix Material Sciences Ltd. Compositions and methods for fabricating synthetic dragline spider silk
CN109477252A (zh) 2016-02-11 2019-03-15 赛威克斯材料科学公司 包括合成拖丝蜘蛛丝的复合材料
JP7113429B2 (ja) 2016-11-29 2022-08-05 Spiber株式会社 タンパク質組成物、その製造方法及び熱安定性向上方法
US20200306163A1 (en) 2017-09-27 2020-10-01 Evolved By Nature, Inc. Materials comprising recombinant silk and methods of preparing the same
CN107595661B (zh) 2017-11-08 2020-09-15 海南蛛王生物科技有限公司 一种包含蜘蛛丝水解物的化妆品及其制备方法
US20200270316A1 (en) 2017-11-10 2020-08-27 Givaudan Sa Silk Alcohol Formulations
US20210138071A1 (en) 2017-11-10 2021-05-13 Cocoon Biotech Inc. Silk-based products and methods of use
US20230201413A1 (en) 2019-03-11 2023-06-29 Seevix Material Sciences Ltd. Compositions comprising dragline spider silk
WO2020184697A1 (ja) 2019-03-13 2020-09-17 国立研究開発法人農業・食品産業技術総合研究機構 繊維強化複合材料及びその製造方法
US20220177530A1 (en) 2019-03-27 2022-06-09 Evolved By Nature, Inc. Recombinant silk based products and methods of preparing the same
JP7007008B2 (ja) 2019-05-29 2022-02-10 Spiber株式会社 構造タンパク質微小体及びその製造方法、ナノファイバーの製造方法、並びにタンパク質構造体の製造方法
AU2020299495A1 (en) 2019-07-04 2022-01-20 Seevix Material Sciences Ltd. Prokaryotic expression system and methods of using the same
AU2020315308A1 (en) 2019-07-12 2022-02-17 Bolt Threads, Inc. Recombinant spider silk extrudate formulations
JP2021054819A (ja) 2019-09-30 2021-04-08 Spiber株式会社 人工構造タンパク質繊維及びその製造方法
WO2021121647A1 (en) 2019-12-18 2021-06-24 Ramirez Rios Liliana Patricia Metal complexes of macrocycles and/or isoprenoids and/or linear tetrapyrroles by mechanochemistry (grinding or milling), preparation method thereof, sunscreen/concealer/uv absorber thereof, self-assembled coating material thereof, superamphiphilic material or surfaces thereof, hair dyeing thereof and other uses thereof
CN111214385B (zh) 2020-03-13 2022-05-17 珀莱雅化妆品股份有限公司 一种负载皮肤营养剂的纳米粒乳液及其制备方法
JP7508248B2 (ja) 2020-03-27 2024-07-01 株式会社コーセー 繊維含有化粧料
CN116406246A (zh) 2020-07-23 2023-07-07 保尔特纺织品公司 重组丝组合物及其制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008507260A (ja) * 2004-06-25 2008-03-13 テヒニシェ ウニヴェルズィテート ミュンヘン 天然起源のタンパク質およびそれから作られる材料
WO2011113592A1 (en) 2010-03-17 2011-09-22 Amsilk Gmbh Method for production of polymer containing fibres
US20120022005A1 (en) 2010-05-24 2012-01-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Synthetic Dragline Spider Silk-Like Proteins
JP2015532690A (ja) * 2012-09-06 2015-11-12 アーエムシルク ゲーエムベーハー 高靱性シルク繊維を作製する方法

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