KR102766038B1 - 아포지질단백질 제형을 위한 용량 용법 - Google Patents

아포지질단백질 제형을 위한 용량 용법 Download PDF

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Publication number
KR102766038B1
KR102766038B1 KR1020207009276A KR20207009276A KR102766038B1 KR 102766038 B1 KR102766038 B1 KR 102766038B1 KR 1020207009276 A KR1020207009276 A KR 1020207009276A KR 20207009276 A KR20207009276 A KR 20207009276A KR 102766038 B1 KR102766038 B1 KR 102766038B1
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South Korea
Prior art keywords
apolipoprotein
formulation
dose
fixed
rhdl
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KR1020207009276A
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Korean (ko)
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KR20200037879A (ko
Inventor
크레이그 레이너
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시에스엘 리미티드
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Priority claimed from AU2011905368A external-priority patent/AU2011905368A0/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020207009276A 2011-12-21 2012-11-02 아포지질단백질 제형을 위한 용량 용법 Active KR102766038B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2011905368A AU2011905368A0 (en) 2011-12-21 Dosing regime for apolipoprotein formulations
AU2011905368 2011-12-21
KR1020197019295A KR20190084334A (ko) 2011-12-21 2012-11-02 아포지질단백질 제형을 위한 용량 용법
PCT/AU2012/001345 WO2013090978A1 (en) 2011-12-21 2012-11-02 Dosage regime for apolipoprotein formulations

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020197019295A Division KR20190084334A (ko) 2011-12-21 2012-11-02 아포지질단백질 제형을 위한 용량 용법

Publications (2)

Publication Number Publication Date
KR20200037879A KR20200037879A (ko) 2020-04-09
KR102766038B1 true KR102766038B1 (ko) 2025-02-12

Family

ID=48667485

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1020207009276A Active KR102766038B1 (ko) 2011-12-21 2012-11-02 아포지질단백질 제형을 위한 용량 용법
KR1020147020291A Ceased KR20140107536A (ko) 2011-12-21 2012-11-02 아포지질단백질 제형을 위한 용량 용법
KR1020197019295A Ceased KR20190084334A (ko) 2011-12-21 2012-11-02 아포지질단백질 제형을 위한 용량 용법

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020147020291A Ceased KR20140107536A (ko) 2011-12-21 2012-11-02 아포지질단백질 제형을 위한 용량 용법
KR1020197019295A Ceased KR20190084334A (ko) 2011-12-21 2012-11-02 아포지질단백질 제형을 위한 용량 용법

Country Status (16)

Country Link
US (3) US20140378376A1 (enExample)
EP (1) EP2793913B1 (enExample)
JP (2) JP6144276B2 (enExample)
KR (3) KR102766038B1 (enExample)
CN (2) CN113398245A (enExample)
AU (1) AU2012310259C1 (enExample)
BR (1) BR112014014403A8 (enExample)
CA (1) CA2857968A1 (enExample)
DK (1) DK2793913T3 (enExample)
ES (1) ES2955110T3 (enExample)
IL (1) IL233236A0 (enExample)
MX (1) MX377093B (enExample)
PL (1) PL2793913T3 (enExample)
RU (1) RU2014129505A (enExample)
SG (1) SG11201402556RA (enExample)
WO (1) WO2013090978A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9645037B2 (en) 2011-09-28 2017-05-09 Hunter Engineering Company Method and apparatus for wheel assembly lateral force measurement
CA2857968A1 (en) * 2011-12-21 2013-06-27 Csl Limited Dosage regime for apolipoprotein formulations
SG11201903945XA (en) 2016-11-10 2019-05-30 Csl Ltd Reconstituted high density lipoprotein treatment of myocardial infarction

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003096983A2 (en) * 2002-05-17 2003-11-27 Esperion Therapeutics, Inc. Method of treating dyslipidemic disorders
WO2004010939A2 (en) 2002-07-30 2004-02-05 Esperion Therapeutics, Inc. Methods of using non-human animal apoliprotein a-i protein
WO2005041866A2 (en) * 2003-10-20 2005-05-12 Esperion Therapeutics, Inc. Pharmaceutical formulations, methods and dosing regimens for the treatment and prevention of acute coronary syndromes
WO2007023476A2 (en) 2005-08-26 2007-03-01 Cerenis Therapeutics Holding Sa Compositions and methods for producing apolipoprotein gene products in lactic acid bacteria

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61152632A (ja) * 1984-12-26 1986-07-11 Dai Ichi Seiyaku Co Ltd 抗動脈硬化剤
US5652339A (en) 1993-12-31 1997-07-29 Rotkreuzstiftung Zentrallaboratorium Method of producing reconstituted lipoproteins
EP1335938B1 (en) * 2000-11-10 2010-09-22 F. Hoffmann-La Roche Ltd. Apolipoprotein construct
CA2460787A1 (en) * 2001-09-28 2003-04-03 Esperion Therapeutics, Inc. Prevention and treatment of restenosis by local administration of drug
AP2006003578A0 (en) * 2003-10-20 2006-04-30 Esperion Therapeutics Inc Pharmaceutical formulations, methods and dosing regimens for the treatment and prevention of acute coronary syndromes.
US20090297577A1 (en) * 2008-06-02 2009-12-03 Medtronic Vascular, Inc. Local Delivery of Apolipoproteins and Their Derivatives
CA2857968A1 (en) * 2011-12-21 2013-06-27 Csl Limited Dosage regime for apolipoprotein formulations

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003096983A2 (en) * 2002-05-17 2003-11-27 Esperion Therapeutics, Inc. Method of treating dyslipidemic disorders
WO2004010939A2 (en) 2002-07-30 2004-02-05 Esperion Therapeutics, Inc. Methods of using non-human animal apoliprotein a-i protein
WO2005041866A2 (en) * 2003-10-20 2005-05-12 Esperion Therapeutics, Inc. Pharmaceutical formulations, methods and dosing regimens for the treatment and prevention of acute coronary syndromes
WO2007023476A2 (en) 2005-08-26 2007-03-01 Cerenis Therapeutics Holding Sa Compositions and methods for producing apolipoprotein gene products in lactic acid bacteria

Also Published As

Publication number Publication date
CA2857968A1 (en) 2013-06-27
MX2014006589A (es) 2014-10-17
US20160175392A1 (en) 2016-06-23
US20240216467A1 (en) 2024-07-04
KR20140107536A (ko) 2014-09-04
AU2012310259C1 (en) 2016-07-14
JP6144276B2 (ja) 2017-06-07
EP2793913B1 (en) 2023-06-21
BR112014014403A2 (pt) 2017-06-13
KR20200037879A (ko) 2020-04-09
IL233236A0 (en) 2014-08-31
RU2017129700A3 (enExample) 2021-02-26
CN104010646A (zh) 2014-08-27
AU2012310259A1 (en) 2013-07-11
JP2017128586A (ja) 2017-07-27
SG11201402556RA (en) 2014-10-30
DK2793913T3 (da) 2023-08-21
HK1199813A1 (en) 2015-07-24
US20140378376A1 (en) 2014-12-25
RU2017129700A (ru) 2019-02-04
BR112014014403A8 (pt) 2021-03-09
JP2015500840A (ja) 2015-01-08
NZ624558A (en) 2015-08-28
WO2013090978A1 (en) 2013-06-27
CN113398245A (zh) 2021-09-17
ES2955110T3 (es) 2023-11-28
AU2012310259B2 (en) 2015-07-30
PL2793913T3 (pl) 2023-11-06
MX377093B (es) 2025-03-07
EP2793913A4 (en) 2015-06-10
RU2014129505A (ru) 2016-02-10
KR20190084334A (ko) 2019-07-16
EP2793913A1 (en) 2014-10-29

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