KR102761870B1 - 인자 h 결합 단백질 변이체 및 이의 사용 방법 - Google Patents
인자 h 결합 단백질 변이체 및 이의 사용 방법 Download PDFInfo
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- KR102761870B1 KR102761870B1 KR1020237036853A KR20237036853A KR102761870B1 KR 102761870 B1 KR102761870 B1 KR 102761870B1 KR 1020237036853 A KR1020237036853 A KR 1020237036853A KR 20237036853 A KR20237036853 A KR 20237036853A KR 102761870 B1 KR102761870 B1 KR 102761870B1
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- 235000011088 sodium lactate Nutrition 0.000 description 1
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 description 1
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 description 1
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- 229940035044 sorbitan monolaurate Drugs 0.000 description 1
- 241000894007 species Species 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462028123P | 2014-07-23 | 2014-07-23 | |
| US62/028,123 | 2014-07-23 | ||
| PCT/US2015/041616 WO2016014719A1 (en) | 2014-07-23 | 2015-07-22 | Factor h binding protein variants and methods of use thereof |
| KR1020177004378A KR102752259B1 (ko) | 2014-07-23 | 2015-07-22 | 인자 h 결합 단백질 변이체 및 이의 사용 방법 |
Related Parent Applications (1)
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Publications (2)
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| KR20230155595A KR20230155595A (ko) | 2023-11-10 |
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| KR1020177004378A Active KR102752259B1 (ko) | 2014-07-23 | 2015-07-22 | 인자 h 결합 단백질 변이체 및 이의 사용 방법 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
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| KR1020177004378A Active KR102752259B1 (ko) | 2014-07-23 | 2015-07-22 | 인자 h 결합 단백질 변이체 및 이의 사용 방법 |
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| US (10) | US10266572B2 (https=) |
| EP (2) | EP4074726A3 (https=) |
| JP (4) | JP6796057B2 (https=) |
| KR (2) | KR102761870B1 (https=) |
| CN (3) | CN119613509A (https=) |
| AU (5) | AU2015292615B2 (https=) |
| BR (1) | BR112017001417B1 (https=) |
| CA (2) | CA3212723A1 (https=) |
| CO (1) | CO2017000558A2 (https=) |
| CR (1) | CR20170020A (https=) |
| ES (1) | ES2922554T3 (https=) |
| MX (3) | MX382409B (https=) |
| NZ (2) | NZ766005A (https=) |
| RU (1) | RU2714248C2 (https=) |
| WO (1) | WO2016014719A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR201802933T4 (tr) | 2010-03-30 | 2018-03-21 | Childrens Hospital & Res Center At Oakland | Özellikleri değiştirilmiş faktör h bağlama proteinleri (fhbp) ve bunların kullanım yöntemi. |
| KR102761870B1 (ko) | 2014-07-23 | 2025-02-05 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 인자 h 결합 단백질 변이체 및 이의 사용 방법 |
| GB201614687D0 (en) * | 2016-08-31 | 2016-10-12 | Univ Oxford Innovation Ltd | fHbp scaffold |
| KR101855139B1 (ko) | 2016-11-16 | 2018-05-08 | 주식회사 케이엠더블유 | Mimo 안테나에서의 캘리브레이션 |
| WO2018093176A2 (ko) | 2016-11-16 | 2018-05-24 | 주식회사 케이엠더블유 | 적층구조의 mimo 안테나 어셈블리 |
| KR102822764B1 (ko) * | 2017-12-04 | 2025-06-19 | 인트라백 비.브이. | 외막 소포의 생성을 위한 개선된 방법 |
| EP3607967A1 (en) * | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| GB202016604D0 (en) | 2020-10-20 | 2020-12-02 | Univ Of Oxford | Compositions and methods for inducing an immune response |
| US12053516B2 (en) | 2021-02-19 | 2024-08-06 | Sanofi Pasteur Inc. | Meningococcal B recombinant vaccine |
| TW202423477A (zh) | 2022-08-03 | 2024-06-16 | 美商賽諾菲巴斯德公司 | 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物 |
| WO2026072910A1 (en) | 2024-09-27 | 2026-04-02 | Sanofi Pasteur Inc. | Anti-meningococcal antibodies for in vitro immunoassay |
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| US20060171957A1 (en) | 2002-10-11 | 2006-08-03 | Chiron Spa | Polypeptide-vaccines for broad protetion against hypervirulent meningococcal lineages |
| US20110256180A1 (en) | 2010-03-30 | 2011-10-20 | Beernink Peter T | Factor H Binding Proteins (FHBP) with Altered Properties and Methods of Use Thereof |
| US20120107339A1 (en) | 2008-03-10 | 2012-05-03 | Granoff Dan M | Chimeric Factor H Binding Proteins (fHBP) Containing a Heterologous B Domain and Methods of Use |
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| EP3169357B1 (en) * | 2014-07-17 | 2018-11-07 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| KR102761870B1 (ko) * | 2014-07-23 | 2025-02-05 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 인자 h 결합 단백질 변이체 및 이의 사용 방법 |
| EP3607967A1 (en) * | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
-
2015
- 2015-07-22 KR KR1020237036853A patent/KR102761870B1/ko active Active
- 2015-07-22 MX MX2017001038A patent/MX382409B/es unknown
- 2015-07-22 WO PCT/US2015/041616 patent/WO2016014719A1/en not_active Ceased
- 2015-07-22 CN CN202411821930.3A patent/CN119613509A/zh active Pending
- 2015-07-22 NZ NZ766005A patent/NZ766005A/en unknown
- 2015-07-22 AU AU2015292615A patent/AU2015292615B2/en active Active
- 2015-07-22 RU RU2017104742A patent/RU2714248C2/ru active
- 2015-07-22 EP EP22174947.6A patent/EP4074726A3/en active Pending
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- 2015-07-22 US US15/327,346 patent/US10266572B2/en active Active
- 2015-07-22 CN CN201580043542.XA patent/CN106715464B/zh active Active
- 2015-07-22 NZ NZ729206A patent/NZ729206A/en unknown
- 2015-07-22 KR KR1020177004378A patent/KR102752259B1/ko active Active
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- 2015-07-22 EP EP15824545.6A patent/EP3172224B1/en active Active
- 2015-07-22 CR CR20170020A patent/CR20170020A/es unknown
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| US20060171957A1 (en) | 2002-10-11 | 2006-08-03 | Chiron Spa | Polypeptide-vaccines for broad protetion against hypervirulent meningococcal lineages |
| US20120107339A1 (en) | 2008-03-10 | 2012-05-03 | Granoff Dan M | Chimeric Factor H Binding Proteins (fHBP) Containing a Heterologous B Domain and Methods of Use |
| US20110256180A1 (en) | 2010-03-30 | 2011-10-20 | Beernink Peter T | Factor H Binding Proteins (FHBP) with Altered Properties and Methods of Use Thereof |
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