KR102754133B1 - 전환 성장 인자-β1에 높은 친화성, 결합력 및 특이성으로 결합하는 ｓｃＦｖ-Ｆｃ 이량체 - Google Patents

전환 성장 인자-β1에 높은 친화성, 결합력 및 특이성으로 결합하는 ｓｃＦｖ-Ｆｃ 이량체 Download PDF

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KR102754133B1
KR102754133B1 KR1020237037758A KR20237037758A KR102754133B1 KR 102754133 B1 KR102754133 B1 KR 102754133B1 KR 1020237037758 A KR1020237037758 A KR 1020237037758A KR 20237037758 A KR20237037758 A KR 20237037758A KR 102754133 B1 KR102754133 B1 KR 102754133B1
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화웨이 추
클라크 팬
줄리 버드
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젠자임 코포레이션
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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KR1020237037758A 2015-03-04 2016-03-03 전환 성장 인자-β1에 높은 친화성, 결합력 및 특이성으로 결합하는 ｓｃＦｖ-Ｆｃ 이량체 Active KR102754133B1 (ko)

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KR1020257000711A KR20250009587A (ko) 2015-03-04 2016-03-03 전환 성장 인자-β1에 높은 친화성, 결합력 및 특이성으로 결합하는 ｓｃＦｖ-Ｆｃ 이량체

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US201562128133P 2015-03-04 2015-03-04
US62/128,133 2015-03-04
PCT/US2016/020779 WO2016141244A1 (en) 2015-03-04 2016-03-03 scFv-Fc DIMERS THAT BIND TRASFORMING GROWTH FACTOR-β1 WITH HIGH AFFINITY, AVIDITY AND SPECIFICITY
KR1020177027371A KR102598790B1 (ko) 2015-03-04 2016-03-03 전환 성장 인자-β1에 높은 친화성, 결합력 및 특이성으로 결합하는 ｓｃＦｖ-Ｆｃ 이량체

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KR102754133B1 true KR102754133B1 (ko) 2025-01-15

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KR1020237037758A Active KR102754133B1 (ko) 2015-03-04 2016-03-03 전환 성장 인자-β1에 높은 친화성, 결합력 및 특이성으로 결합하는 ｓｃＦｖ-Ｆｃ 이량체
KR1020257000711A Pending KR20250009587A (ko) 2015-03-04 2016-03-03 전환 성장 인자-β1에 높은 친화성, 결합력 및 특이성으로 결합하는 ｓｃＦｖ-Ｆｃ 이량체
KR1020177027371A Active KR102598790B1 (ko) 2015-03-04 2016-03-03 전환 성장 인자-β1에 높은 친화성, 결합력 및 특이성으로 결합하는 ｓｃＦｖ-Ｆｃ 이량체

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KR1020177027371A Active KR102598790B1 (ko) 2015-03-04 2016-03-03 전환 성장 인자-β1에 높은 친화성, 결합력 및 특이성으로 결합하는 ｓｃＦｖ-Ｆｃ 이량체

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US (4) US10508146B2 (enExample)
EP (2) EP3265484B1 (enExample)
JP (1) JP6845802B2 (enExample)
KR (3) KR102754133B1 (enExample)
CN (1) CN107889491B (enExample)
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BR (1) BR112017018767A2 (enExample)
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TWI726870B (zh) 2015-03-04 2021-05-11 美商健臻公司 具有高親和性、結合性及專一性之結合轉形生長因子-β１的ｓｃＦｖ-Ｆｃ二聚體
TWI733661B (zh) 2015-03-04 2021-07-21 美商健臻公司 以高親合性、結合性及特異性結合轉化生長因子－β１的經修飾ＩｇＧ抗體
EP3448987A4 (en) 2016-04-29 2020-05-27 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
EP3448874A4 (en) 2016-04-29 2020-04-22 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
US20220119513A1 (en) * 2020-06-08 2022-04-21 Zoetis Services Llc Anti-tgfb antibodies and therapeutic uses thereof
CN112500491B (zh) * 2020-12-18 2022-04-08 深圳市迈加瑞生物技术有限公司 一种特异性中和辅助性T细胞TGF-β信号的双特异性抗体、其药物组合及其用途
CN116179493A (zh) * 2021-09-29 2023-05-30 成都美杰赛尔生物科技有限公司 敲除两种免疫检测点基因的免疫细胞及其制备方法与应用

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